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The map label for this gene is folB

Identifier: 94309128

GI number: 94309128

Start: 189891

End: 190289

Strand: Direct

Name: folB

Synonym: Rmet_0183

Alternate gene names: NA

Gene position: 189891-190289 (Clockwise)

Preceding gene: 94309127

Following gene: 94309129

Centisome position: 4.83

GC content: 61.4

Gene sequence:

>399_bases
ATGACCTTTGCCGCCCTTTCCCATCCCAGCCTGCAAAACTGCCGTCGCATGTTCCTGCGCAACTATGAAGTGCAGATCAA
CATTGGCGTGCACGAATTCGAGAAGAAGGGCGAACAGCGCGTGCTCGTCAATATCGACCTGTTCGTGTCGCTGGCCGAGA
CCACGCCGCAGGCCGACAAGCTCGAGGAAGTGGTCGACTACGACTTCATGCGCAACACCGTGGCCGAGCGCATGGCGCGT
GGCCATATCCACCTGCAGGAAACGCTGTGCGACGACGTGGCGCGTGCCATGCTGCAGCATCCGAAGGTGCGCGCCGTGCG
CGTGTCGACCGAAAAACCGGACGTCTACCCGGATTGCGATGCCGTCGGCGTGGAAGTGTTCCACGTCAAGCCCGCCTGA

Upstream 100 bases:

>100_bases
TACCGGCACCACGTTGTACGTCGACGGAGGCCAGCACCTGATGCCGCTGGCCCGCGACGTGATGTTCCTTACTGAATAAG
CTGTTTCTGATTTGCCAGCC

Downstream 100 bases:

>100_bases
TCTGGCCGCTCTGCCCGAGCGGGACCGCGCAGCGCCGGGCGGTGGGCTCCAGTAGAATGTTGGCCCGTTGAAACCGGGCC
ATTGTTCAGCGCCCGTACTG

Product: dihydroneopterin aldolase

Products: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; glycolaldehyde

Alternate protein names: Dihydroneopterin Aldolase Family Protein; Dihydroneopterin Aldolase Protein

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MTFAALSHPSLQNCRRMFLRNYEVQINIGVHEFEKKGEQRVLVNIDLFVSLAETTPQADKLEEVVDYDFMRNTVAERMAR
GHIHLQETLCDDVARAMLQHPKVRAVRVSTEKPDVYPDCDAVGVEVFHVKPA

Sequences:

>Translated_132_residues
MTFAALSHPSLQNCRRMFLRNYEVQINIGVHEFEKKGEQRVLVNIDLFVSLAETTPQADKLEEVVDYDFMRNTVAERMAR
GHIHLQETLCDDVARAMLQHPKVRAVRVSTEKPDVYPDCDAVGVEVFHVKPA
>Mature_131_residues
TFAALSHPSLQNCRRMFLRNYEVQINIGVHEFEKKGEQRVLVNIDLFVSLAETTPQADKLEEVVDYDFMRNTVAERMARG
HIHLQETLCDDVARAMLQHPKVRAVRVSTEKPDVYPDCDAVGVEVFHVKPA

Specific function: Unknown

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.25

Molecular weight: Translated: 15123; Mature: 14991

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAALSHPSLQNCRRMFLRNYEVQINIGVHEFEKKGEQRVLVNIDLFVSLAETTPQADK
CCCCCCCCCCHHHHHHHHHCCCEEEEEECHHHHHCCCCCEEEEEEHHEEEECCCCCCHHH
LEEVVDYDFMRNTVAERMARGHIHLQETLCDDVARAMLQHPKVRAVRVSTEKPDVYPDCD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
AVGVEVFHVKPA
CCCEEEEEECCC
>Mature Secondary Structure 
TFAALSHPSLQNCRRMFLRNYEVQINIGVHEFEKKGEQRVLVNIDLFVSLAETTPQADK
CCCCCCCCCHHHHHHHHHCCCEEEEEECHHHHHCCCCCEEEEEEHHEEEECCCCCCHHH
LEEVVDYDFMRNTVAERMARGHIHLQETLCDDVARAMLQHPKVRAVRVSTEKPDVYPDCD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
AVGVEVFHVKPA
CCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-; $dihydropteridine

Specific reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8- $dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA