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The map label for this gene is crt [H]

Identifier: 94309025

GI number: 94309025

Start: 86899

End: 87726

Strand: Reverse

Name: crt [H]

Synonym: Rmet_0080

Alternate gene names: 94309025

Gene position: 87726-86899 (Counterclockwise)

Preceding gene: 94309026

Following gene: 94309024

Centisome position: 2.23

GC content: 65.94

Gene sequence:

>828_bases
ATGACCACTTCCGACGCCAATACCCTGCCCCCGCGCCTTGCGCGCTATCGCGCCCTGACCCTGCGCCGCCACGGCCCCAT
CCTTGAGGTGATCATGGGCGCGGCCCAATCGGCCAACCAGAAACTGGCCACCGCCGACGCCTCCATGCACCGCGAACTGG
CCGAGATCTGGCGTGATATTTCGGCGGAACCCGAAATCCGCGTGGCGCTGATCCGTGGCGAAGGCAAGGGCTTCTCGGCC
GGCGGCGACCTCGGACTGGTCGAGGAGATGGCCAACGATTTCGAGACGCGCACCCGCGTCTGGCATGAGGCACGCGACCT
GGTCTACAACGTCATCAACTGCGACAAGCCGATCGTCTCCGCGATGCATGGCCCGGCCGTTGGCGCGGGGCTGGTAGCCG
GGCTGCTGGCCGATATCTCGATCGCGGCAAAGACCGCGCGCATCGTGGATGGCCATACCCGGCTGGGTGTGGCCGCCGGC
GATCATGCCGCCATCGTCTGGCCGTTGCTGTGCGGAATGGCCAAGGCCAAGTACTATCTGATGCTGTGCGAGTCGGTCAG
CGGCGAGGAAGCCGAGCGGATCGGCCTGGTATCGCTGGCGGTGGAAGAAGACGAACTGGTCGCGAAAGCGTTCGAGGTGG
CCAACCGGCTTGCTGCCGGATCGCAGACCGCCATCCGCTGGACCAAGTACGCGCTCAACAACTGGCTGCGCATGGCCGGC
CCCGCGTTCGATACCTCGCTGGCGCTCGAATTCATGGGCTTTGCCGGCCCCGACGTGCACGAAGGCATGGCGAGCCTGCG
TCAGAAGCGGCCGCCCGAATTCAAGTAA

Upstream 100 bases:

>100_bases
ATTCGACGCGTCTTCCTTGCGTCCCTTCGCGCTCCTTCGCCTCTTTCGGACATCCAGTTCCCCTGCCCGGCGGCCCGAAA
CTTCTTCGATACCCGCCCAA

Downstream 100 bases:

>100_bases
CCGGTCGTCCTGCTCACGTTTCGGGACGACCATGTCAGACGGAGTTGCGCGACCATGTTCGGACAGTTACCCGATTTCAC
CAACAGCTACGAGTTCCTTC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTTSDANTLPPRLARYRALTLRRHGPILEVIMGAAQSANQKLATADASMHRELAEIWRDISAEPEIRVALIRGEGKGFSA
GGDLGLVEEMANDFETRTRVWHEARDLVYNVINCDKPIVSAMHGPAVGAGLVAGLLADISIAAKTARIVDGHTRLGVAAG
DHAAIVWPLLCGMAKAKYYLMLCESVSGEEAERIGLVSLAVEEDELVAKAFEVANRLAAGSQTAIRWTKYALNNWLRMAG
PAFDTSLALEFMGFAGPDVHEGMASLRQKRPPEFK

Sequences:

>Translated_275_residues
MTTSDANTLPPRLARYRALTLRRHGPILEVIMGAAQSANQKLATADASMHRELAEIWRDISAEPEIRVALIRGEGKGFSA
GGDLGLVEEMANDFETRTRVWHEARDLVYNVINCDKPIVSAMHGPAVGAGLVAGLLADISIAAKTARIVDGHTRLGVAAG
DHAAIVWPLLCGMAKAKYYLMLCESVSGEEAERIGLVSLAVEEDELVAKAFEVANRLAAGSQTAIRWTKYALNNWLRMAG
PAFDTSLALEFMGFAGPDVHEGMASLRQKRPPEFK
>Mature_274_residues
TTSDANTLPPRLARYRALTLRRHGPILEVIMGAAQSANQKLATADASMHRELAEIWRDISAEPEIRVALIRGEGKGFSAG
GDLGLVEEMANDFETRTRVWHEARDLVYNVINCDKPIVSAMHGPAVGAGLVAGLLADISIAAKTARIVDGHTRLGVAAGD
HAAIVWPLLCGMAKAKYYLMLCESVSGEEAERIGLVSLAVEEDELVAKAFEVANRLAAGSQTAIRWTKYALNNWLRMAGP
AFDTSLALEFMGFAGPDVHEGMASLRQKRPPEFK

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=230, Percent_Identity=24.3478260869565, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4502327, Length=225, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20127408, Length=169, Percent_Identity=28.9940828402367, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787659, Length=222, Percent_Identity=30.6306306306306, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI221142681, Length=218, Percent_Identity=29.3577981651376, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=28.8, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788597, Length=226, Percent_Identity=24.3362831858407, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=231, Percent_Identity=25.974025974026, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=240, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=232, Percent_Identity=25.4310344827586, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=183, Percent_Identity=25.6830601092896, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=203, Percent_Identity=24.1379310344828, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20129971, Length=234, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653477, Length=234, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922422, Length=212, Percent_Identity=27.3584905660377, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24653139, Length=240, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24654903, Length=193, Percent_Identity=22.7979274611399, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 29735; Mature: 29603

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSDANTLPPRLARYRALTLRRHGPILEVIMGAAQSANQKLATADASMHRELAEIWRDI
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
SAEPEIRVALIRGEGKGFSAGGDLGLVEEMANDFETRTRVWHEARDLVYNVINCDKPIVS
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AMHGPAVGAGLVAGLLADISIAAKTARIVDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
MLCESVSGEEAERIGLVSLAVEEDELVAKAFEVANRLAAGSQTAIRWTKYALNNWLRMAG
HHHCCCCCCHHHHHEEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PAFDTSLALEFMGFAGPDVHEGMASLRQKRPPEFK
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTSDANTLPPRLARYRALTLRRHGPILEVIMGAAQSANQKLATADASMHRELAEIWRDI
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
SAEPEIRVALIRGEGKGFSAGGDLGLVEEMANDFETRTRVWHEARDLVYNVINCDKPIVS
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AMHGPAVGAGLVAGLLADISIAAKTARIVDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
MLCESVSGEEAERIGLVSLAVEEDELVAKAFEVANRLAAGSQTAIRWTKYALNNWLRMAG
HHHCCCCCCHHHHHEEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PAFDTSLALEFMGFAGPDVHEGMASLRQKRPPEFK
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]