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The map label for this gene is kdpE [H]

Identifier: 94308987

GI number: 94308987

Start: 47311

End: 48006

Strand: Direct

Name: kdpE [H]

Synonym: Rmet_0042

Alternate gene names: 94308987

Gene position: 47311-48006 (Clockwise)

Preceding gene: 94308986

Following gene: 94308988

Centisome position: 1.2

GC content: 66.38

Gene sequence:

>696_bases
ATGCCTTTTGATTATTCGCCGACCGTGTTGCTGGTCGAGGACGAACCCCACATCCGCCGCTTCGTGCGTGAATCGCTGCA
GTCCGAGGGCTGCACGGTGCACGAGGCCGATACGCTCAAGCGCGGCCTGATTGACGCCGGCACGCGCCAGCCGGATGTGG
TGATCCTGGACCTTGGCCTGCCTGATGGCGATGGCATGACACTGATCCGCGAGATGCGCACCTGGACCGAGGTGCCTGTG
CTGGTGCTATCGGCACGCACTGGCGAAGCCGACAAGATCGCCGCGCTCGATGCGGGCGCGGACGACTACCTGACCAAGCC
GTTCGGCGTCGGTGAACTGGTGGCGCGCGTGCGCGTGCTGCTGCGCCGGCACGCCAAGGCGAATCCACAAGGCACGCCCC
AGATCACGTTCGGCGACGTGCGCGTGGACCTGGCCAACCGGCTCGTCACGCGCGGCGAAGATCAGGTGCATCTGACGCCG
ATCGAATACCGCCTGCTGGCCGTGCTGATCGCCAATCGTGGCAAGGTCATGACGCACCGGGAACTGCTGCGCGAGGTCTG
GGGCCCCTCGCACTCGGAGAGCAGCCACTACCTGCGGGTCTATATGGGCCACCTGCGCCACAAGCTCGAGGTCGATCCGG
CCCAGCCCGCGCATCTGCTGACAGAGGTGGGCGTCGGATACCGGTTCGCCGGCTGA

Upstream 100 bases:

>100_bases
CACCCACATGGTTCGCGATTCACGCTGGCGCTGCCGCGCGGCAATCCACCGGCTATCGAGCCAGAGTCGCTGGACGAACC
CATTCCGGATCATCACTGAC

Downstream 100 bases:

>100_bases
GCCAGATTATAAGAATGACGAATAATAACGAAGAATAATTTGAGTCGATAATCTGTTATCGACATATAAGTTCCCACGGA
TCGCCCACTACACTGAATCA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPFDYSPTVLLVEDEPHIRRFVRESLQSEGCTVHEADTLKRGLIDAGTRQPDVVILDLGLPDGDGMTLIREMRTWTEVPV
LVLSARTGEADKIAALDAGADDYLTKPFGVGELVARVRVLLRRHAKANPQGTPQITFGDVRVDLANRLVTRGEDQVHLTP
IEYRLLAVLIANRGKVMTHRELLREVWGPSHSESSHYLRVYMGHLRHKLEVDPAQPAHLLTEVGVGYRFAG

Sequences:

>Translated_231_residues
MPFDYSPTVLLVEDEPHIRRFVRESLQSEGCTVHEADTLKRGLIDAGTRQPDVVILDLGLPDGDGMTLIREMRTWTEVPV
LVLSARTGEADKIAALDAGADDYLTKPFGVGELVARVRVLLRRHAKANPQGTPQITFGDVRVDLANRLVTRGEDQVHLTP
IEYRLLAVLIANRGKVMTHRELLREVWGPSHSESSHYLRVYMGHLRHKLEVDPAQPAHLLTEVGVGYRFAG
>Mature_230_residues
PFDYSPTVLLVEDEPHIRRFVRESLQSEGCTVHEADTLKRGLIDAGTRQPDVVILDLGLPDGDGMTLIREMRTWTEVPVL
VLSARTGEADKIAALDAGADDYLTKPFGVGELVARVRVLLRRHAKANPQGTPQITFGDVRVDLANRLVTRGEDQVHLTPI
EYRLLAVLIANRGKVMTHRELLREVWGPSHSESSHYLRVYMGHLRHKLEVDPAQPAHLLTEVGVGYRFAG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=64.8648648648649, Blast_Score=303, Evalue=6e-84,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=37.219730941704, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=36.6515837104072, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=35, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=31.390134529148, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.7391304347826, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=31.0344827586207, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=35.5263157894737, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=32.15859030837, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=33.1818181818182, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=31.4655172413793, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=30.5676855895196, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=29.1866028708134, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=28.936170212766, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.9622641509434, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25794; Mature: 25663

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDYSPTVLLVEDEPHIRRFVRESLQSEGCTVHEADTLKRGLIDAGTRQPDVVILDLGL
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCCEEEEECCC
PDGDGMTLIREMRTWTEVPVLVLSARTGEADKIAALDAGADDYLTKPFGVGELVARVRVL
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHH
LRRHAKANPQGTPQITFGDVRVDLANRLVTRGEDQVHLTPIEYRLLAVLIANRGKVMTHR
HHHHHCCCCCCCCEEEECCEEHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCHHHH
ELLREVWGPSHSESSHYLRVYMGHLRHKLEVDPAQPAHLLTEVGVGYRFAG
HHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHCCCEEECC
>Mature Secondary Structure 
PFDYSPTVLLVEDEPHIRRFVRESLQSEGCTVHEADTLKRGLIDAGTRQPDVVILDLGL
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCCEEEEECCC
PDGDGMTLIREMRTWTEVPVLVLSARTGEADKIAALDAGADDYLTKPFGVGELVARVRVL
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHH
LRRHAKANPQGTPQITFGDVRVDLANRLVTRGEDQVHLTPIEYRLLAVLIANRGKVMTHR
HHHHHCCCCCCCCEEEECCEEHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCHHHH
ELLREVWGPSHSESSHYLRVYMGHLRHKLEVDPAQPAHLLTEVGVGYRFAG
HHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]