Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 93007244

GI number: 93007244

Start: 2990944

End: 2993256

Strand: Direct

Name: rnr [H]

Synonym: Pcryo_2420

Alternate gene names: 93007244

Gene position: 2990944-2993256 (Clockwise)

Preceding gene: 93007243

Following gene: 93007248

Centisome position: 97.75

GC content: 43.58

Gene sequence:

>2313_bases
ATGAGTTGGAATGATCCAAACGCCTCAAGTGAGGCACAAAAATATGATAACCCGATTCCTAGTCGCGAGCTTATATTAAG
CACGATTAATGAACACGGTGAAATCACCCATCAGCAATTGGCAAAAGCCTTTAATATTGCTGATCCCGATCAGTTTGACG
CTTTAGGCAACCGCCTAAAAGCGATGACACGCGATGGACAAGTCAATCGTGACGGTCGCCCTTATCGCTATCGTACGGTC
ACTCAGCACGACATCGTCACCGGTACAGTAACAGCCCATCCAAAGGGCTTTGGCTTTGTATTATTAAGTGATATGCCTGA
CCTATTCTTGCATGAAAAACAAATGCGTTGGGTCTTTAATGGCGATACAGTAGAAGCCGTTGGCACGTCAACAGACAACC
GCGGTCGTACTGAAGGTCGTATCGTTGATGTCGTTGAGCGTCGTCAAAATCATTTTATCGGTACGCTGGCTCATGATGAA
GACGGTTACTGCGTTGAGCTTGGTAGCCCAAATAACCATCAGCCGATTACCGTTACAGAAGACAATGTACAGGCTTTCAA
TGCTAAGCAAGGCTCGCCGGTAAAAGTTGATATTATTGATTGGCCAAATCAGCATGAATTTGCCACGGGCAAAATCACTG
AAGTCTTATCTGATGACAATGATCGCGAACTGATCATTGAGACTACGTTACTTAATTATGATATTCCATCAGAGTTCAGT
GAAGCGGCGCTCAATCAAGCAAATGATTATAAAGAGCCGACTGAAAAAGATCTAAAAGGTCGTGTCGACTTACGTGAGTT
GCCATTAGTGACGATCGATGGTGAAGATGCTCGTGACTTTGATGATGCTGTGTTTGCAGAAAAGCGTTCTGGTGGTAATT
ATCGCGTCTTGGTAGCGATTGCGGATGTCAGTTATTATGTGACACCGAACTCGCCACTTGATCAAAATGCCTACGAGCGT
GGTACGTCAGTATATTTCCCGCATCAAGTGATTCCTATGTTGCCTGAAGTACTGTCTAATGGTCTCTGTTCGCTGAACCC
TAATCTTGATCGCCTCTGTATGGTTGCTGATATTAAGATATCACGTGCTGGTAAAATCACCAGTTATGAGTTTTATCCTG
GCGTCATGCACTCGCAAGCGCGCTTGACTTACAATCAAGTGAACGCTTATCTTGAGAATCCAAAAGACAGTAGCGTTCCA
AAATCGTTGACAGAAAATAAAGAGGTCAAAAAATCTGTCGATACCTTACATCAACTGTATGAGCTACTCCTCAAAAAGCG
TGAAGAGCGTCATGCGATGGAGTTTGAGACCGTTGAAACTTATATTAAGTTCAATGAAAAAGGTGGTATCGAAGCCATCT
TGCCTCGTACGCGCGGTGATGCGCAAAAGCTTATCGAAGAGTGCATGTTGCTTGCCAATACCTGTGCAGCAAACTTTGCG
CTAAAAAATGAGCTGCCTGTGTTATATCGTAATCATGATAAGCCTGATGGCGAAAAGTCGATGCGTATCCATGAATATGC
CAAAAACTTTGGTCTAAGCTTCCCAGAAGAAAATCCTACTCAAGCAGATTATCAGCGTATCATTGAAGCAACTAAAGAGC
GACCGGATGCGATTAGCATTCATAGCATGCTGCTTCGTTCGATGATGCAAGCGAACTATTCACCTGACAATATCGGTCAC
TTTGGTTTGGCTTACGATGAGTATAGTCATTTTACCTCGCCGATTCGTCGTTATCCTGACTTAATGTTGCATCGTGCGAT
CAAGGCGAAAGTGACAAATGCCAAACAGCCTGTGATGGATTTTTCATTAGAAGGTGCTGGCATGCAAACCTCAGATACTG
AGCGCCGTGCTGAAAAGGCTTCACGCTACGTAGAATCATGGCTCAAATGTCATTATATGAAAGATCATGTCGGCGAAGAG
TTCGATGGTGTCGTAACTACCGTCACAAACTTTGGTTTATTTATTACTCTGACGGATTTGTATATCGATGGTTTGGTGCA
TATCTCAAACGTTGGTGACGATTTCTTTGTTTATGATGAGCAGCAGCAACAGCTTATCGGTAAAGATAGAGGCACAGTGT
TTGGGCTGGGCGATTTGGTTAAAGTTAAAGTAGCTGGCGTTAATATGGATCTGCTACAAATTGACTTTGGTTTACAAGCA
AAGCTGCAATCTAGTAAAATGAATCAAACTAAGAAAGATCATTCAAACTCTAGTCAGCCAAACCGCAGCTCCACAAGCAA
AGATCAGCCAAAGAAATCACCTGCGAAGAGAAGCGGCAGTCGTGGTGGTAGAGGCAGTAGTAAAAAGAGCTAA

Upstream 100 bases:

>100_bases
TCGCTATCAAATACAGATAAGACAATTGACCTAAGATATTGGGACGTTGTTCGTGTTAAGATAGTCATTATTAATAATTT
AAAAATAGATACGGTAATTT

Downstream 100 bases:

>100_bases
ACTAGCTTGAATCTATAAGTATTAAAAAAGGCTAACGTTATCGTTAGCCTTTTTTGTGTCTTCAGTTTTCTAATAACAGA
TCTATCACTGCTCCGCAGGA

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MSWNDPNASSEAQKYDNPIPSRELILSTINEHGEITHQQLAKAFNIADPDQFDALGNRLKAMTRDGQVNRDGRPYRYRTV
TQHDIVTGTVTAHPKGFGFVLLSDMPDLFLHEKQMRWVFNGDTVEAVGTSTDNRGRTEGRIVDVVERRQNHFIGTLAHDE
DGYCVELGSPNNHQPITVTEDNVQAFNAKQGSPVKVDIIDWPNQHEFATGKITEVLSDDNDRELIIETTLLNYDIPSEFS
EAALNQANDYKEPTEKDLKGRVDLRELPLVTIDGEDARDFDDAVFAEKRSGGNYRVLVAIADVSYYVTPNSPLDQNAYER
GTSVYFPHQVIPMLPEVLSNGLCSLNPNLDRLCMVADIKISRAGKITSYEFYPGVMHSQARLTYNQVNAYLENPKDSSVP
KSLTENKEVKKSVDTLHQLYELLLKKREERHAMEFETVETYIKFNEKGGIEAILPRTRGDAQKLIEECMLLANTCAANFA
LKNELPVLYRNHDKPDGEKSMRIHEYAKNFGLSFPEENPTQADYQRIIEATKERPDAISIHSMLLRSMMQANYSPDNIGH
FGLAYDEYSHFTSPIRRYPDLMLHRAIKAKVTNAKQPVMDFSLEGAGMQTSDTERRAEKASRYVESWLKCHYMKDHVGEE
FDGVVTTVTNFGLFITLTDLYIDGLVHISNVGDDFFVYDEQQQQLIGKDRGTVFGLGDLVKVKVAGVNMDLLQIDFGLQA
KLQSSKMNQTKKDHSNSSQPNRSSTSKDQPKKSPAKRSGSRGGRGSSKKS

Sequences:

>Translated_770_residues
MSWNDPNASSEAQKYDNPIPSRELILSTINEHGEITHQQLAKAFNIADPDQFDALGNRLKAMTRDGQVNRDGRPYRYRTV
TQHDIVTGTVTAHPKGFGFVLLSDMPDLFLHEKQMRWVFNGDTVEAVGTSTDNRGRTEGRIVDVVERRQNHFIGTLAHDE
DGYCVELGSPNNHQPITVTEDNVQAFNAKQGSPVKVDIIDWPNQHEFATGKITEVLSDDNDRELIIETTLLNYDIPSEFS
EAALNQANDYKEPTEKDLKGRVDLRELPLVTIDGEDARDFDDAVFAEKRSGGNYRVLVAIADVSYYVTPNSPLDQNAYER
GTSVYFPHQVIPMLPEVLSNGLCSLNPNLDRLCMVADIKISRAGKITSYEFYPGVMHSQARLTYNQVNAYLENPKDSSVP
KSLTENKEVKKSVDTLHQLYELLLKKREERHAMEFETVETYIKFNEKGGIEAILPRTRGDAQKLIEECMLLANTCAANFA
LKNELPVLYRNHDKPDGEKSMRIHEYAKNFGLSFPEENPTQADYQRIIEATKERPDAISIHSMLLRSMMQANYSPDNIGH
FGLAYDEYSHFTSPIRRYPDLMLHRAIKAKVTNAKQPVMDFSLEGAGMQTSDTERRAEKASRYVESWLKCHYMKDHVGEE
FDGVVTTVTNFGLFITLTDLYIDGLVHISNVGDDFFVYDEQQQQLIGKDRGTVFGLGDLVKVKVAGVNMDLLQIDFGLQA
KLQSSKMNQTKKDHSNSSQPNRSSTSKDQPKKSPAKRSGSRGGRGSSKKS
>Mature_769_residues
SWNDPNASSEAQKYDNPIPSRELILSTINEHGEITHQQLAKAFNIADPDQFDALGNRLKAMTRDGQVNRDGRPYRYRTVT
QHDIVTGTVTAHPKGFGFVLLSDMPDLFLHEKQMRWVFNGDTVEAVGTSTDNRGRTEGRIVDVVERRQNHFIGTLAHDED
GYCVELGSPNNHQPITVTEDNVQAFNAKQGSPVKVDIIDWPNQHEFATGKITEVLSDDNDRELIIETTLLNYDIPSEFSE
AALNQANDYKEPTEKDLKGRVDLRELPLVTIDGEDARDFDDAVFAEKRSGGNYRVLVAIADVSYYVTPNSPLDQNAYERG
TSVYFPHQVIPMLPEVLSNGLCSLNPNLDRLCMVADIKISRAGKITSYEFYPGVMHSQARLTYNQVNAYLENPKDSSVPK
SLTENKEVKKSVDTLHQLYELLLKKREERHAMEFETVETYIKFNEKGGIEAILPRTRGDAQKLIEECMLLANTCAANFAL
KNELPVLYRNHDKPDGEKSMRIHEYAKNFGLSFPEENPTQADYQRIIEATKERPDAISIHSMLLRSMMQANYSPDNIGHF
GLAYDEYSHFTSPIRRYPDLMLHRAIKAKVTNAKQPVMDFSLEGAGMQTSDTERRAEKASRYVESWLKCHYMKDHVGEEF
DGVVTTVTNFGLFITLTDLYIDGLVHISNVGDDFFVYDEQQQQLIGKDRGTVFGLGDLVKVKVAGVNMDLLQIDFGLQAK
LQSSKMNQTKKDHSNSSQPNRSSTSKDQPKKSPAKRSGSRGGRGSSKKS

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=470, Percent_Identity=29.7872340425532, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI190014623, Length=470, Percent_Identity=29.7872340425532, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI134288890, Length=513, Percent_Identity=28.6549707602339, Blast_Score=170, Evalue=5e-42,
Organism=Homo sapiens, GI19115966, Length=613, Percent_Identity=26.7536704730832, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI219521928, Length=613, Percent_Identity=26.7536704730832, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI156105695, Length=295, Percent_Identity=24.7457627118644, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI156105693, Length=297, Percent_Identity=25.2525252525253, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082383, Length=735, Percent_Identity=44.6258503401361, Blast_Score=586, Evalue=1e-168,
Organism=Escherichia coli, GI1787542, Length=642, Percent_Identity=27.1028037383178, Blast_Score=179, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17553506, Length=456, Percent_Identity=29.8245614035088, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI212645896, Length=473, Percent_Identity=29.3868921775898, Blast_Score=159, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=515, Percent_Identity=27.1844660194175, Blast_Score=167, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6323943, Length=441, Percent_Identity=24.7165532879819, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649634, Length=479, Percent_Identity=28.1837160751566, Blast_Score=166, Evalue=8e-41,
Organism=Drosophila melanogaster, GI19922976, Length=382, Percent_Identity=29.0575916230367, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24654597, Length=382, Percent_Identity=29.0575916230367, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24654592, Length=382, Percent_Identity=29.0575916230367, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 86856; Mature: 86725

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWNDPNASSEAQKYDNPIPSRELILSTINEHGEITHQQLAKAFNIADPDQFDALGNRLK
CCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
AMTRDGQVNRDGRPYRYRTVTQHDIVTGTVTAHPKGFGFVLLSDMPDLFLHEKQMRWVFN
HHHCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHEEEEC
GDTVEAVGTSTDNRGRTEGRIVDVVERRQNHFIGTLAHDEDGYCVELGSPNNHQPITVTE
CCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCEEEEC
DNVQAFNAKQGSPVKVDIIDWPNQHEFATGKITEVLSDDNDRELIIETTLLNYDIPSEFS
CCCCEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCEEEEEEEEECCCCCHHHH
EAALNQANDYKEPTEKDLKGRVDLRELPLVTIDGEDARDFDDAVFAEKRSGGNYRVLVAI
HHHHHHCCCCCCCCHHHHCCCCCHHHCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEE
ADVSYYVTPNSPLDQNAYERGTSVYFPHQVIPMLPEVLSNGLCSLNPNLDRLCMVADIKI
EEEEEEECCCCCCCCHHHHCCCEEECCHHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEE
SRAGKITSYEFYPGVMHSQARLTYNQVNAYLENPKDSSVPKSLTENKEVKKSVDTLHQLY
ECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
ELLLKKREERHAMEFETVETYIKFNEKGGIEAILPRTRGDAQKLIEECMLLANTCAANFA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCEE
LKNELPVLYRNHDKPDGEKSMRIHEYAKNFGLSFPEENPTQADYQRIIEATKERPDAISI
ECCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
HSMLLRSMMQANYSPDNIGHFGLAYDEYSHFTSPIRRYPDLMLHRAIKAKVTNAKQPVMD
HHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
FSLEGAGMQTSDTERRAEKASRYVESWLKCHYMKDHVGEEFDGVVTTVTNFGLFITLTDL
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHCCEEEEEHHH
YIDGLVHISNVGDDFFVYDEQQQQLIGKDRGTVFGLGDLVKVKVAGVNMDLLQIDFGLQA
HHCCEEEEECCCCCEEEECHHHHHHHCCCCCCEEECCCEEEEEEECCCEEEEEECCCCHH
KLQSSKMNQTKKDHSNSSQPNRSSTSKDQPKKSPAKRSGSRGGRGSSKKS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SWNDPNASSEAQKYDNPIPSRELILSTINEHGEITHQQLAKAFNIADPDQFDALGNRLK
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
AMTRDGQVNRDGRPYRYRTVTQHDIVTGTVTAHPKGFGFVLLSDMPDLFLHEKQMRWVFN
HHHCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHEEEEC
GDTVEAVGTSTDNRGRTEGRIVDVVERRQNHFIGTLAHDEDGYCVELGSPNNHQPITVTE
CCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCEEEEC
DNVQAFNAKQGSPVKVDIIDWPNQHEFATGKITEVLSDDNDRELIIETTLLNYDIPSEFS
CCCCEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCEEEEEEEEECCCCCHHHH
EAALNQANDYKEPTEKDLKGRVDLRELPLVTIDGEDARDFDDAVFAEKRSGGNYRVLVAI
HHHHHHCCCCCCCCHHHHCCCCCHHHCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEE
ADVSYYVTPNSPLDQNAYERGTSVYFPHQVIPMLPEVLSNGLCSLNPNLDRLCMVADIKI
EEEEEEECCCCCCCCHHHHCCCEEECCHHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEE
SRAGKITSYEFYPGVMHSQARLTYNQVNAYLENPKDSSVPKSLTENKEVKKSVDTLHQLY
ECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
ELLLKKREERHAMEFETVETYIKFNEKGGIEAILPRTRGDAQKLIEECMLLANTCAANFA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCEE
LKNELPVLYRNHDKPDGEKSMRIHEYAKNFGLSFPEENPTQADYQRIIEATKERPDAISI
ECCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
HSMLLRSMMQANYSPDNIGHFGLAYDEYSHFTSPIRRYPDLMLHRAIKAKVTNAKQPVMD
HHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
FSLEGAGMQTSDTERRAEKASRYVESWLKCHYMKDHVGEEFDGVVTTVTNFGLFITLTDL
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHCCEEEEEHHH
YIDGLVHISNVGDDFFVYDEQQQQLIGKDRGTVFGLGDLVKVKVAGVNMDLLQIDFGLQA
HHCCEEEEECCCCCEEEECHHHHHHHCCCCCCEEECCCEEEEEEECCCEEEEEECCCCHH
KLQSSKMNQTKKDHSNSSQPNRSSTSKDQPKKSPAKRSGSRGGRGSSKKS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]