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The map label for this gene is dtd

Identifier: 93007041

GI number: 93007041

Start: 2721880

End: 2722335

Strand: Reverse

Name: dtd

Synonym: Pcryo_2217

Alternate gene names: 93007041

Gene position: 2722335-2721880 (Counterclockwise)

Preceding gene: 93007048

Following gene: 93007040

Centisome position: 88.97

GC content: 43.64

Gene sequence:

>456_bases
ATGAGATCTCTTATTCAGCGAGTCAAATATGCCAGTGTCAGCGTTGATGGGCAGGAGGTCGGTGCTATTGAGCAAGGTGT
GCTGGCATATATCGGCTTGGGACACGATGATAACCTACAAAGTGCGCAGCGGATGATTGATAAAATCCTCACCTATCGTA
TTTTTGACAATGATGATGATCCAGCCAAATACGGCAAAGTCGATAAAAATGTCCAGCAAGTCGGTGGTGGGCTATTATTG
GTCTCACAATTTACTCTGATGGCAAAGACGGATAAAGGTCGCCGCCCTGAATTTGGTAGCGCAATGGCACCTGATATGGC
TCAAGCTTTATTTGCACAATTGGTTGATTATGCAAAGACGCAGTATTTAACGGTTGCAACGGGTCAGTTTGGCGCTGATA
TGCAAGTATTGAGTGTCAATGATGGACCATTAAACTTTTTATTAGAAGTGCATTAA

Upstream 100 bases:

>100_bases
ATTTATTTATAAACATAATCATAAGTACATACACAGATAATTGTATTTTATCATGGTCCGCAGCAGACTGTATGACCATA
ATCGTTAAAGGAAGTAAGCA

Downstream 100 bases:

>100_bases
GTCATTAGCATGGCTACTAAGTATTATAAATTTAAGAGTAAATGTCATTAAGCTGTCATAATTAAGCCCTTTAATGAAGA
AACGCTTATTTGCGTTTGTT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MRSLIQRVKYASVSVDGQEVGAIEQGVLAYIGLGHDDNLQSAQRMIDKILTYRIFDNDDDPAKYGKVDKNVQQVGGGLLL
VSQFTLMAKTDKGRRPEFGSAMAPDMAQALFAQLVDYAKTQYLTVATGQFGADMQVLSVNDGPLNFLLEVH

Sequences:

>Translated_151_residues
MRSLIQRVKYASVSVDGQEVGAIEQGVLAYIGLGHDDNLQSAQRMIDKILTYRIFDNDDDPAKYGKVDKNVQQVGGGLLL
VSQFTLMAKTDKGRRPEFGSAMAPDMAQALFAQLVDYAKTQYLTVATGQFGADMQVLSVNDGPLNFLLEVH
>Mature_151_residues
MRSLIQRVKYASVSVDGQEVGAIEQGVLAYIGLGHDDNLQSAQRMIDKILTYRIFDNDDDPAKYGKVDKNVQQVGGGLLL
VSQFTLMAKTDKGRRPEFGSAMAPDMAQALFAQLVDYAKTQYLTVATGQFGADMQVLSVNDGPLNFLLEVH

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=151, Percent_Identity=34.4370860927152, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1790320, Length=150, Percent_Identity=46.6666666666667, Blast_Score=139, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=36.4864864864865, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=151, Percent_Identity=33.7748344370861, Blast_Score=95, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=36.4238410596026, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_PSYCK (Q1Q8K9)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_581478.1
- ProteinModelPortal:   Q1Q8K9
- SMR:   Q1Q8K9
- STRING:   Q1Q8K9
- GeneID:   4033830
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_2217
- NMPDR:   fig|335284.3.peg.2197
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q1Q8K9
- ProtClustDB:   PRK05273
- BioCyc:   PCRY335284:PCRYO_2217-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16544; Mature: 16544

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: ACT_SITE 85-85

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLIQRVKYASVSVDGQEVGAIEQGVLAYIGLGHDDNLQSAQRMIDKILTYRIFDNDDD
CHHHHHHHHHHHCCCCCHHHCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCC
PAKYGKVDKNVQQVGGGLLLVSQFTLMAKTDKGRRPEFGSAMAPDMAQALFAQLVDYAKT
CHHHCCCHHHHHHHCCCEEEEHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QYLTVATGQFGADMQVLSVNDGPLNFLLEVH
CEEEEECCCCCCCEEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MRSLIQRVKYASVSVDGQEVGAIEQGVLAYIGLGHDDNLQSAQRMIDKILTYRIFDNDDD
CHHHHHHHHHHHCCCCCHHHCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCC
PAKYGKVDKNVQQVGGGLLLVSQFTLMAKTDKGRRPEFGSAMAPDMAQALFAQLVDYAKT
CHHHCCCHHHHHHHCCCEEEEHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QYLTVATGQFGADMQVLSVNDGPLNFLLEVH
CEEEEECCCCCCCEEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA