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The map label for this gene is ccmA [H]

Identifier: 93006937

GI number: 93006937

Start: 2586715

End: 2587356

Strand: Reverse

Name: ccmA [H]

Synonym: Pcryo_2113

Alternate gene names: 93006937

Gene position: 2587356-2586715 (Counterclockwise)

Preceding gene: 93006941

Following gene: 93006936

Centisome position: 84.56

GC content: 47.2

Gene sequence:

>642_bases
ATGAGAGGTTGTATGACGGCTCTGAATACCGCCTTACTTGCGCTTGATGAGCTGACCGTTCAGCGTGGTGAAATCCCTCT
ATGTGAAGGGGTGTCACTCAAGTTGTCTGCAGGCAGCATTTGCCATCTAATTGGTGCCAATGGTACCGGCAAGACCACGT
TACTTATGCAACTGGCTGGATTATTGCCAGTGCTAACAGGTGAGACTTATTATCAAGGGGCAGTTAGCTTACCGATTCAG
CCTTTGTATGTATCGCATCAATTGGGCATTCATCCCAATCTCACTGTTGCTCAAAATCTCACCTTTTTGCTGAATTTATA
TGGTATCACACCAAGCGCTGCTGATATTGATGACGCCCTCACTTGGGTAGGATTACAAGGGTTTGAAACCATAAGCTCAA
GTCATTTATCCGCGGGTCAAACTCGAAGAATTACCCTTGCGCGGTTATACTTACTGACGCCTGAAGTGACGCCATTATGG
TTGCTTGATGAGCCATTCACCGCACTCGATGTTGATATGGTAGCCCGCATGGAAGACCGATTACGCGATTTTGCTCATGA
AGGCGGGGCGATATTAATGACCAGTCACCAGGCAGTCGACGTTGCCAATCAAGTGCTCGATTTGTCCGATTACATGGTAT
GA

Upstream 100 bases:

>100_bases
AATCGACAATTTGTTATACTGTATGGTTATGGGGCATAAAGTATTATGCCACGAACATCGTCTTGGTTTGTGATGAATAT
TGACTGCGGGTCAATAAATA

Downstream 100 bases:

>100_bases
ATACTATCAATATCAGTGCGATAAGCATCAGTGGAAGAGTGTATAAATGATAGAAACAGACAGTTCATTATCAATCATAA
ATGCTCATACAGCTGATGTG

Product: heme exporter protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRGCMTALNTALLALDELTVQRGEIPLCEGVSLKLSAGSICHLIGANGTGKTTLLMQLAGLLPVLTGETYYQGAVSLPIQ
PLYVSHQLGIHPNLTVAQNLTFLLNLYGITPSAADIDDALTWVGLQGFETISSSHLSAGQTRRITLARLYLLTPEVTPLW
LLDEPFTALDVDMVARMEDRLRDFAHEGGAILMTSHQAVDVANQVLDLSDYMV

Sequences:

>Translated_213_residues
MRGCMTALNTALLALDELTVQRGEIPLCEGVSLKLSAGSICHLIGANGTGKTTLLMQLAGLLPVLTGETYYQGAVSLPIQ
PLYVSHQLGIHPNLTVAQNLTFLLNLYGITPSAADIDDALTWVGLQGFETISSSHLSAGQTRRITLARLYLLTPEVTPLW
LLDEPFTALDVDMVARMEDRLRDFAHEGGAILMTSHQAVDVANQVLDLSDYMV
>Mature_213_residues
MRGCMTALNTALLALDELTVQRGEIPLCEGVSLKLSAGSICHLIGANGTGKTTLLMQLAGLLPVLTGETYYQGAVSLPIQ
PLYVSHQLGIHPNLTVAQNLTFLLNLYGITPSAADIDDALTWVGLQGFETISSSHLSAGQTRRITLARLYLLTPEVTPLW
LLDEPFTALDVDMVARMEDRLRDFAHEGGAILMTSHQAVDVANQVLDLSDYMV

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=203, Percent_Identity=28.0788177339901, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI171184400, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082064, Length=199, Percent_Identity=40.2010050251256, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87081709, Length=191, Percent_Identity=29.8429319371728, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081791, Length=196, Percent_Identity=32.6530612244898, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788225, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786563, Length=212, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787370, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788002, Length=180, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786872, Length=177, Percent_Identity=29.3785310734463, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787712, Length=216, Percent_Identity=26.8518518518519, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1786319, Length=182, Percent_Identity=27.4725274725275, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1788450, Length=150, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1788761, Length=202, Percent_Identity=29.2079207920792, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1790467, Length=212, Percent_Identity=25.4716981132075, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787029, Length=198, Percent_Identity=25.7575757575758, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI48994943, Length=172, Percent_Identity=31.3953488372093, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI87081782, Length=190, Percent_Identity=27.8947368421053, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788165, Length=188, Percent_Identity=31.3829787234043, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789751, Length=193, Percent_Identity=29.0155440414508, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI87082268, Length=220, Percent_Identity=25.9090909090909, Blast_Score=60, Evalue=8e-11,
Organism=Escherichia coli, GI1789991, Length=218, Percent_Identity=28.4403669724771, Blast_Score=60, Evalue=9e-11,
Organism=Escherichia coli, GI1789032, Length=183, Percent_Identity=27.8688524590164, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 23004; Mature: 23004

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGCMTALNTALLALDELTVQRGEIPLCEGVSLKLSAGSICHLIGANGTGKTTLLMQLAG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHH
LLPVLTGETYYQGAVSLPIQPLYVSHQLGIHPNLTVAQNLTFLLNLYGITPSAADIDDAL
HHHHHCCCCHHCCEECCCCCEEEEEEECCCCCCCHHHHHHEEEEEEECCCCCCCCHHHHH
TWVGLQGFETISSSHLSAGQTRRITLARLYLLTPEVTPLWLLDEPFTALDVDMVARMEDR
HHHCCCHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHH
LRDFAHEGGAILMTSHQAVDVANQVLDLSDYMV
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGCMTALNTALLALDELTVQRGEIPLCEGVSLKLSAGSICHLIGANGTGKTTLLMQLAG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHH
LLPVLTGETYYQGAVSLPIQPLYVSHQLGIHPNLTVAQNLTFLLNLYGITPSAADIDDAL
HHHHHCCCCHHCCEECCCCCEEEEEEECCCCCCCHHHHHHEEEEEEECCCCCCCCHHHHH
TWVGLQGFETISSSHLSAGQTRRITLARLYLLTPEVTPLWLLDEPFTALDVDMVARMEDR
HHHCCCHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHH
LRDFAHEGGAILMTSHQAVDVANQVLDLSDYMV
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA