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The map label for this gene is trxC [C]

Identifier: 93006890

GI number: 93006890

Start: 2534040

End: 2534474

Strand: Reverse

Name: trxC [C]

Synonym: Pcryo_2066

Alternate gene names: 93006890

Gene position: 2534474-2534040 (Counterclockwise)

Preceding gene: 93006891

Following gene: 93006885

Centisome position: 82.83

GC content: 44.6

Gene sequence:

>435_bases
ATGAGTGAAAAAAATGCTCATGTAGTATGCCCACATTGCCAAGCAACGAATCGTGTACCAGATTCCAAACTCAGTGCTGC
ACCAAACTGCGGTAAATGTGCGAAGCCTTTACTGACTGCAACGCCGCATGAGTTAAATGCCCAAACGGTGAGTAAAGTCA
TTCAAAAAAATGAAGTGCTGACCATCGTAGACTTCTGGGCCAGTTGGTGTCAACCTTGTCTTATGATGGCACCGGAGTTC
AAGATAGCTGCCAGCCAGTTGCCACAAATCGTGTTTGCTAAAATACAAACCGATAAATATGAGCAAGCAGCGGCGCCTTA
TAATATTCGCAGTTTACCAACGATGGTAGCATTTAAAAATGGTAAAGAGATAGCACGGCAGTCGGGAGCGTTACCAAGCC
ATCAAATCGTGCAATGGGTACAAAGCTTAAAGTAG

Upstream 100 bases:

>100_bases
TGGGGAATAAACACCGTGTTAGTACAGTGCTGTTTCATCCAACTCATCCATGTCTTTTTATGATAATTTCATATTTATGA
TAATTTAACGGAGTCTTATT

Downstream 100 bases:

>100_bases
TTGTTATTGCAATAAATGCTGTCTCATAAGTCTGACTTTATTGAATTCAACAAAAAGCCAATACGTGTATCGCGTATTGG
CTTTTTTATTATGCTGGATG

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSEKNAHVVCPHCQATNRVPDSKLSAAPNCGKCAKPLLTATPHELNAQTVSKVIQKNEVLTIVDFWASWCQPCLMMAPEF
KIAASQLPQIVFAKIQTDKYEQAAAPYNIRSLPTMVAFKNGKEIARQSGALPSHQIVQWVQSLK

Sequences:

>Translated_144_residues
MSEKNAHVVCPHCQATNRVPDSKLSAAPNCGKCAKPLLTATPHELNAQTVSKVIQKNEVLTIVDFWASWCQPCLMMAPEF
KIAASQLPQIVFAKIQTDKYEQAAAPYNIRSLPTMVAFKNGKEIARQSGALPSHQIVQWVQSLK
>Mature_143_residues
SEKNAHVVCPHCQATNRVPDSKLSAAPNCGKCAKPLLTATPHELNAQTVSKVIQKNEVLTIVDFWASWCQPCLMMAPEFK
IAASQLPQIVFAKIQTDKYEQAAAPYNIRSLPTMVAFKNGKEIARQSGALPSHQIVQWVQSLK

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=136, Percent_Identity=33.8235294117647, Blast_Score=108, Evalue=1e-25,
Organism=Escherichia coli, GI87082331, Length=99, Percent_Identity=34.3434343434343, Blast_Score=70, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI212646193, Length=94, Percent_Identity=39.3617021276596, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71998175, Length=79, Percent_Identity=40.5063291139241, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71980565, Length=75, Percent_Identity=36, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71980562, Length=79, Percent_Identity=34.1772151898734, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=74, Percent_Identity=41.8918918918919, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321648, Length=88, Percent_Identity=34.0909090909091, Blast_Score=68, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24658597, Length=71, Percent_Identity=38.0281690140845, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 15872; Mature: 15740

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKNAHVVCPHCQATNRVPDSKLSAAPNCGKCAKPLLTATPHELNAQTVSKVIQKNEVL
CCCCCCEEECCCCCCCCCCCCCHHCCCCCCCHHHCCHHCCCCCCCCHHHHHHHHHCCCCH
TIVDFWASWCQPCLMMAPEFKIAASQLPQIVFAKIQTDKYEQAAAPYNIRSLPTMVAFKN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHCCC
GKEIARQSGALPSHQIVQWVQSLK
CHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SEKNAHVVCPHCQATNRVPDSKLSAAPNCGKCAKPLLTATPHELNAQTVSKVIQKNEVL
CCCCCEEECCCCCCCCCCCCCHHCCCCCCCHHHCCHHCCCCCCCCHHHHHHHHHCCCCH
TIVDFWASWCQPCLMMAPEFKIAASQLPQIVFAKIQTDKYEQAAAPYNIRSLPTMVAFKN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHCCC
GKEIARQSGALPSHQIVQWVQSLK
CHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8652661 [H]