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The map label for this gene is katA [H]

Identifier: 93006823

GI number: 93006823

Start: 2459203

End: 2460747

Strand: Reverse

Name: katA [H]

Synonym: Pcryo_1999

Alternate gene names: 93006823

Gene position: 2460747-2459203 (Counterclockwise)

Preceding gene: 93006824

Following gene: 93006822

Centisome position: 80.42

GC content: 46.54

Gene sequence:

>1545_bases
ATGAGCGACAACAACAGTAATAATAGCAGCGATAAAAAATGTCCTTACGCCCCGACCCAATTGACGATGAGCAACGGCGC
ACCAGTTGCAGACAATCAAAACAGTCTCACTGCAGGCAAGCGTGGTCCATTATTAGCACAAGATATCTGGCTAAACGAGA
AGCTAGGCAACTTTGCCCGTGAAGTGATTCCAGAGCGCCGCATGCACGCTAAAGGCTCAGGCGCATTTGGTACTTTTACC
GTGACCAATGACATCACTAAATATACCCGTGCGGATATTTTTAGCGAAGTGGGTAAGCAAACGGAAATGTTTGCGCGCTT
TAGTACCGTCGCAGGTGAGCGCGGCGCGGCTGATGCCGAACGCGATATTCGTGGCTTTGCTTTGAAATTCTACACCGAAG
AAGGTAATTGGGACATGGTGGGTAATAATACGCCTGTGTTCTTCTTACGTGATCCGCGCAAATTCCCAGATTTAAACAAA
GCCGTCAAACGTGATCCACGTACCAATATGCGTTCGGCGACCAACAATTGGGACTTTTGGACTTTATTACCTGAAGCATT
ACATCAAGTCACCATCGTTATGAGTGATCGCGGTCTGCCAGCCTCGTACAGAAATATGCATGGTTTTGGCTCGCACACGT
ATAGTTTTTGGAATGAAGCCAAAGAACGTTTCTGGGTCAAATTCCATTTCCGCACGCAACAAGGCATCAAGAACTTGACC
GATGCAGAAGCGGCAGAGGTGGTTGGTTCGGATCGTGAAAGTCATCAAAAAGACTTGTACGATGCCATCGAAAATCGTCA
TTTCCCAAAATGGAAAATGTATGTGCAAATCATGCCAGAAGCTGAGGCGGATACCGTTCCTTATCATCCGTTTGACTTGA
CCAAAGTATGGCCAAAAGGGGATTACCCACTGATCGAAGTGGGTGAGTTTGAATTAAACAAAAACTCTGACAACTACTTT
GTCGATGTGGAACAAGCAGCATTTGCCCCAAGTAATTTAGTACCGGGTATCAGCGTTTCACCGGATAAAATGCTACAAAA
TCGCTTGGTTAACTATGCCGATGCTCAGCGTTATCGTGTTGGTGTCAATCATCAGCAAATTCCGGTGAATAAGCCGCGTT
GCCCTGTGATGAGCAATCATCGTGATGGTCAAGGACGTGTCGATGATAACTATGGCAGTCGCCCGCATTATGAACCAAAC
AGCTTTAGCCAGTGGCAAGAGCAGCCTGATTATGCTGAGCCACCATTAAAAATTGACGGCTATGCGGCGCATTATGATTT
CCGTGAAGACGATAGCGATTATTTCAGTCAACCGAGAGCGTTGTTTAATTTGATGAGTGCTGAGCAACAACAAGTGCTAT
TTGAAAACACAGCGAACAATATGGCGGGTGTGCCGGACTTTATTCAGTATCGCCACATTCGCAACTGTAACTGGTGTGAT
GCTGCTTATGGCGAAGGCGTTGCCAAAGCATTAGGTTTAACGGTTGAAGATGCAATGGCAGCCCGTGATTCGGATCCTGC
TCGTCATTTGCCTAGCTGCTTATAG

Upstream 100 bases:

>100_bases
TTTTTCAGAAACATTTACAACTATTCTGGATATGTTATTAGAGGCTTATTCAGAATAGGTTTTGTACTTTCATCCATTTG
CTATCCAAAGGAATATGATT

Downstream 100 bases:

>100_bases
CTGATAGGTTTATCTAAAAACGTATTACTAAATATACTTGCTAAATCTATTATCATTACAATGACACCGCCTCAGGAAAC
TAGAGCGGTGTTTTTTATTG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MSDNNSNNSSDKKCPYAPTQLTMSNGAPVADNQNSLTAGKRGPLLAQDIWLNEKLGNFAREVIPERRMHAKGSGAFGTFT
VTNDITKYTRADIFSEVGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFFLRDPRKFPDLNK
AVKRDPRTNMRSATNNWDFWTLLPEALHQVTIVMSDRGLPASYRNMHGFGSHTYSFWNEAKERFWVKFHFRTQQGIKNLT
DAEAAEVVGSDRESHQKDLYDAIENRHFPKWKMYVQIMPEAEADTVPYHPFDLTKVWPKGDYPLIEVGEFELNKNSDNYF
VDVEQAAFAPSNLVPGISVSPDKMLQNRLVNYADAQRYRVGVNHQQIPVNKPRCPVMSNHRDGQGRVDDNYGSRPHYEPN
SFSQWQEQPDYAEPPLKIDGYAAHYDFREDDSDYFSQPRALFNLMSAEQQQVLFENTANNMAGVPDFIQYRHIRNCNWCD
AAYGEGVAKALGLTVEDAMAARDSDPARHLPSCL

Sequences:

>Translated_514_residues
MSDNNSNNSSDKKCPYAPTQLTMSNGAPVADNQNSLTAGKRGPLLAQDIWLNEKLGNFAREVIPERRMHAKGSGAFGTFT
VTNDITKYTRADIFSEVGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFFLRDPRKFPDLNK
AVKRDPRTNMRSATNNWDFWTLLPEALHQVTIVMSDRGLPASYRNMHGFGSHTYSFWNEAKERFWVKFHFRTQQGIKNLT
DAEAAEVVGSDRESHQKDLYDAIENRHFPKWKMYVQIMPEAEADTVPYHPFDLTKVWPKGDYPLIEVGEFELNKNSDNYF
VDVEQAAFAPSNLVPGISVSPDKMLQNRLVNYADAQRYRVGVNHQQIPVNKPRCPVMSNHRDGQGRVDDNYGSRPHYEPN
SFSQWQEQPDYAEPPLKIDGYAAHYDFREDDSDYFSQPRALFNLMSAEQQQVLFENTANNMAGVPDFIQYRHIRNCNWCD
AAYGEGVAKALGLTVEDAMAARDSDPARHLPSCL
>Mature_513_residues
SDNNSNNSSDKKCPYAPTQLTMSNGAPVADNQNSLTAGKRGPLLAQDIWLNEKLGNFAREVIPERRMHAKGSGAFGTFTV
TNDITKYTRADIFSEVGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFFLRDPRKFPDLNKA
VKRDPRTNMRSATNNWDFWTLLPEALHQVTIVMSDRGLPASYRNMHGFGSHTYSFWNEAKERFWVKFHFRTQQGIKNLTD
AEAAEVVGSDRESHQKDLYDAIENRHFPKWKMYVQIMPEAEADTVPYHPFDLTKVWPKGDYPLIEVGEFELNKNSDNYFV
DVEQAAFAPSNLVPGISVSPDKMLQNRLVNYADAQRYRVGVNHQQIPVNKPRCPVMSNHRDGQGRVDDNYGSRPHYEPNS
FSQWQEQPDYAEPPLKIDGYAAHYDFREDDSDYFSQPRALFNLMSAEQQQVLFENTANNMAGVPDFIQYRHIRNCNWCDA
AYGEGVAKALGLTVEDAMAARDSDPARHLPSCL

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=473, Percent_Identity=47.9915433403806, Blast_Score=462, Evalue=1e-130,
Organism=Escherichia coli, GI48994891, Length=495, Percent_Identity=39.5959595959596, Blast_Score=340, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI25151141, Length=476, Percent_Identity=46.4285714285714, Blast_Score=444, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI25147792, Length=476, Percent_Identity=46.0084033613445, Blast_Score=443, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI71998444, Length=453, Percent_Identity=47.9028697571744, Blast_Score=440, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6320462, Length=483, Percent_Identity=45.5486542443064, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321525, Length=362, Percent_Identity=42.5414364640884, Blast_Score=294, Evalue=3e-80,
Organism=Drosophila melanogaster, GI17981717, Length=481, Percent_Identity=44.9064449064449, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI19920968, Length=478, Percent_Identity=43.0962343096234, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 58536; Mature: 58404

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNNSNNSSDKKCPYAPTQLTMSNGAPVADNQNSLTAGKRGPLLAQDIWLNEKLGNFAR
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EVIPERRMHAKGSGAFGTFTVTNDITKYTRADIFSEVGKQTEMFARFSTVAGERGAADAE
HHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
RDIRGFALKFYTEEGNWDMVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMRSATNNWDFW
HCCCEEEEEEEEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCCHH
TLLPEALHQVTIVMSDRGLPASYRNMHGFGSHTYSFWNEAKERFWVKFHFRTQQGIKNLT
HHHHHHHCEEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHEEEEEEEEECHHHHHHHH
DAEAAEVVGSDRESHQKDLYDAIENRHFPKWKMYVQIMPEAEADTVPYHPFDLTKVWPKG
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECCCC
DYPLIEVGEFELNKNSDNYFVDVEQAAFAPSNLVPGISVSPDKMLQNRLVNYADAQRYRV
CCCEEEECEEEECCCCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHCCHHEEE
GVNHQQIPVNKPRCPVMSNHRDGQGRVDDNYGSRPHYEPNSFSQWQEQPDYAEPPLKIDG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEECC
YAAHYDFREDDSDYFSQPRALFNLMSAEQQQVLFENTANNMAGVPDFIQYRHIRNCNWCD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC
AAYGEGVAKALGLTVEDAMAARDSDPARHLPSCL
HHHHHHHHHHHCCCHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
SDNNSNNSSDKKCPYAPTQLTMSNGAPVADNQNSLTAGKRGPLLAQDIWLNEKLGNFAR
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EVIPERRMHAKGSGAFGTFTVTNDITKYTRADIFSEVGKQTEMFARFSTVAGERGAADAE
HHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
RDIRGFALKFYTEEGNWDMVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMRSATNNWDFW
HCCCEEEEEEEEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCCHH
TLLPEALHQVTIVMSDRGLPASYRNMHGFGSHTYSFWNEAKERFWVKFHFRTQQGIKNLT
HHHHHHHCEEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHEEEEEEEEECHHHHHHHH
DAEAAEVVGSDRESHQKDLYDAIENRHFPKWKMYVQIMPEAEADTVPYHPFDLTKVWPKG
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECCCC
DYPLIEVGEFELNKNSDNYFVDVEQAAFAPSNLVPGISVSPDKMLQNRLVNYADAQRYRV
CCCEEEECEEEECCCCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHCCHHEEE
GVNHQQIPVNKPRCPVMSNHRDGQGRVDDNYGSRPHYEPNSFSQWQEQPDYAEPPLKIDG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEECC
YAAHYDFREDDSDYFSQPRALFNLMSAEQQQVLFENTANNMAGVPDFIQYRHIRNCNWCD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC
AAYGEGVAKALGLTVEDAMAARDSDPARHLPSCL
HHHHHHHHHHHCCCHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8188593; 7542800 [H]