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The map label for this gene is htpG

Identifier: 93006822

GI number: 93006822

Start: 2456944

End: 2458944

Strand: Reverse

Name: htpG

Synonym: Pcryo_1998

Alternate gene names: 93006822

Gene position: 2458944-2456944 (Counterclockwise)

Preceding gene: 93006823

Following gene: 93006821

Centisome position: 80.36

GC content: 43.68

Gene sequence:

>2001_bases
ATGAGTGAACTGAACCCAGTTGATAATCAAAAAGTTGATAGCATCAATGTTGATAAAAGCAGCCCAGAATTAAAAAAACA
TACCTTTGAAGCAGAAGTAGCTCAATTATTGCACTTAGTGACGCACTCGCTATATTCTAATTCCGATATTTTTGTCCGTG
AGCTGGTTTCAAACGCCTCTGATGCCTGTGATAAATTGCGCTTTGAAGCGACCAATGATGACAGCCTTTATGAAGACGAT
GGCGAGCTAAAAATTCGCATTGCCGTCGATGAAGACGCTAAAACCATCACCTTTACCGACAACGGTATCGGGATGAACGA
AGCTGATGCCATCGAAAACTTAGGCACAATTGCCAAATCTGGCACTAAAGCATTTTTAGACAAGCTGTCTGAATCACAAA
AGCAAGATGGTCAGTTGATTGGTCAATTCGGGGTTGGCTTTTATTCGGGCTTTATCGTTGCCGATACGATCAGTGTTGAA
ACCCGCAAAGCTGGCGAACCTGCGGATAAAGGCGTACGCTGGGTATCAGATGGTACGGGTAGCTTTACCGTTGAGCCTAT
CACTAAAGAAACTCGTGGCACCGCCATTACTTTGCATTTAAAAGAGCAATATAGTGAGGGTGAAGAAAGCTATTTAGACC
GTGGCAAAATTAAGCAGTTGGTTAATAAATACTCAGACCATATCAGCTTGCCGATTCAGATGCGTAAAGAAGTTTGGCAA
GAAGATGAGGTTGAAGAAGGAAGCGACACGCCTGCCAATGGTCAAATGGTCTTAACAGACGAATGGGAAACTATCAATAA
AGCCAGTGCCTTATGGACACGTTCAGCCTCTGAGATTGAAGATGAAGAGTATATCGATTTTTATAAAAATATCACCTATG
ACATGGACGCGCCACTAGCATGGACGCATAACCGTGTCGAAGGTCGTGTTCAGTATACTCAGCTATTGTATATTCCTAAA
AAAGCCCCTGTAGATTTGTACACTCGTGAGCAGCAGCATGGTCTAAAGCTTTATGTTAAGCGCGTCTTTATTATGGACGA
GGCAGAGCAGCTGTTGCCAATGTACCTGCGTTTCGTCAAAGGTGTCATCGATTCAGCAGACTTGCCATTGAACGTCAGCC
GCGAGCTATTACAAGAGTCGCGTGATGTGAAGTCTATCCGCGATGGTAACGCGCGTCGTATTTTGACTTTGCTAGCCAGT
CTAGCCAACAGTGAAGACAGTGATAAGCAAGAAAAATTTGCGCAGTTCTACGCTGAATTTGGTGATGTTATCAAAGAAGG
CGTTGGCGAAGACATGGGCAATCAAGAACGTATTGCCAAATTGCTGCGTTATGCAACCAGTACTCAGGATAGTGTGACGA
CCAGCTTTGAAGACTATAAAGCACGTATGAAAGAGGGTCAAAAAGCCATCTATTATCTCACGGCTGACAATCTAGCGGCT
GCTAAAAATAGCCCACAATTAGAGCTATTCAAAAAGAAAGGCATCGAAGTTATCTTGATGACTAGCCGTGTTGATGAGTG
GGCGATGAATTTCTTGACCTCATTTGATGAGACACCGCTACAAAACATCGCTAAAGGTGCCGTTGATTTGGGCGACTTGC
AAGACGAAGCCGAAAAAGCTGAAGCTGAAAAAGCGCAAGAAACCATGAAGCCTATCGTTGATAAGCTAAAAACGGCGTTA
GGCGAACGTGCCAAAGACGTTAAAGTATCGACGCGTTTGGTTGATAGTCCTGCCTGCTTAGTCGTTGGTGAAGGTGAGTT
ATCACCACAAATGATTCAGATGCTTAAGCAAATGGGTCAAGATGTGCCAGAAAGCAAGCCGACGCTTGAGGTTAACCCTG
ATCATCCATTGATTAAAAAGCTTGAAAGTAGCGAGCAGTCAGCCGAAGATTTTGATAAATTGGCGCAAGTTATTTTCGAC
CAAGCATTACTAGCAGATGGCGGTCAGTTAGATGATCCAGCCGCTTATCTCAGACGTGTTAATGAGTTATTAATGAGATA
A

Upstream 100 bases:

>100_bases
CAGTGTTCAAAACGTAAGCTCTCTAATATTCATTGAGTAAGTTTCGTTTGAGGACTGCTATCTTATAATAAGTTTTTAAC
ATAAATTGAAGGAGTTTTTT

Downstream 100 bases:

>100_bases
TGTTCAAGGTTTGATAGAAGGTTTTGATAAAAAAGGAGGTCTTAAGTTTAAGACCTCCTTTTTTGATGGGTTTTTAAGCG
AATTTTACAATTCAGCCTTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MSELNPVDNQKVDSINVDKSSPELKKHTFEAEVAQLLHLVTHSLYSNSDIFVRELVSNASDACDKLRFEATNDDSLYEDD
GELKIRIAVDEDAKTITFTDNGIGMNEADAIENLGTIAKSGTKAFLDKLSESQKQDGQLIGQFGVGFYSGFIVADTISVE
TRKAGEPADKGVRWVSDGTGSFTVEPITKETRGTAITLHLKEQYSEGEESYLDRGKIKQLVNKYSDHISLPIQMRKEVWQ
EDEVEEGSDTPANGQMVLTDEWETINKASALWTRSASEIEDEEYIDFYKNITYDMDAPLAWTHNRVEGRVQYTQLLYIPK
KAPVDLYTREQQHGLKLYVKRVFIMDEAEQLLPMYLRFVKGVIDSADLPLNVSRELLQESRDVKSIRDGNARRILTLLAS
LANSEDSDKQEKFAQFYAEFGDVIKEGVGEDMGNQERIAKLLRYATSTQDSVTTSFEDYKARMKEGQKAIYYLTADNLAA
AKNSPQLELFKKKGIEVILMTSRVDEWAMNFLTSFDETPLQNIAKGAVDLGDLQDEAEKAEAEKAQETMKPIVDKLKTAL
GERAKDVKVSTRLVDSPACLVVGEGELSPQMIQMLKQMGQDVPESKPTLEVNPDHPLIKKLESSEQSAEDFDKLAQVIFD
QALLADGGQLDDPAAYLRRVNELLMR

Sequences:

>Translated_666_residues
MSELNPVDNQKVDSINVDKSSPELKKHTFEAEVAQLLHLVTHSLYSNSDIFVRELVSNASDACDKLRFEATNDDSLYEDD
GELKIRIAVDEDAKTITFTDNGIGMNEADAIENLGTIAKSGTKAFLDKLSESQKQDGQLIGQFGVGFYSGFIVADTISVE
TRKAGEPADKGVRWVSDGTGSFTVEPITKETRGTAITLHLKEQYSEGEESYLDRGKIKQLVNKYSDHISLPIQMRKEVWQ
EDEVEEGSDTPANGQMVLTDEWETINKASALWTRSASEIEDEEYIDFYKNITYDMDAPLAWTHNRVEGRVQYTQLLYIPK
KAPVDLYTREQQHGLKLYVKRVFIMDEAEQLLPMYLRFVKGVIDSADLPLNVSRELLQESRDVKSIRDGNARRILTLLAS
LANSEDSDKQEKFAQFYAEFGDVIKEGVGEDMGNQERIAKLLRYATSTQDSVTTSFEDYKARMKEGQKAIYYLTADNLAA
AKNSPQLELFKKKGIEVILMTSRVDEWAMNFLTSFDETPLQNIAKGAVDLGDLQDEAEKAEAEKAQETMKPIVDKLKTAL
GERAKDVKVSTRLVDSPACLVVGEGELSPQMIQMLKQMGQDVPESKPTLEVNPDHPLIKKLESSEQSAEDFDKLAQVIFD
QALLADGGQLDDPAAYLRRVNELLMR
>Mature_665_residues
SELNPVDNQKVDSINVDKSSPELKKHTFEAEVAQLLHLVTHSLYSNSDIFVRELVSNASDACDKLRFEATNDDSLYEDDG
ELKIRIAVDEDAKTITFTDNGIGMNEADAIENLGTIAKSGTKAFLDKLSESQKQDGQLIGQFGVGFYSGFIVADTISVET
RKAGEPADKGVRWVSDGTGSFTVEPITKETRGTAITLHLKEQYSEGEESYLDRGKIKQLVNKYSDHISLPIQMRKEVWQE
DEVEEGSDTPANGQMVLTDEWETINKASALWTRSASEIEDEEYIDFYKNITYDMDAPLAWTHNRVEGRVQYTQLLYIPKK
APVDLYTREQQHGLKLYVKRVFIMDEAEQLLPMYLRFVKGVIDSADLPLNVSRELLQESRDVKSIRDGNARRILTLLASL
ANSEDSDKQEKFAQFYAEFGDVIKEGVGEDMGNQERIAKLLRYATSTQDSVTTSFEDYKARMKEGQKAIYYLTADNLAAA
KNSPQLELFKKKGIEVILMTSRVDEWAMNFLTSFDETPLQNIAKGAVDLGDLQDEAEKAEAEKAQETMKPIVDKLKTALG
ERAKDVKVSTRLVDSPACLVVGEGELSPQMIQMLKQMGQDVPESKPTLEVNPDHPLIKKLESSEQSAEDFDKLAQVIFDQ
ALLADGGQLDDPAAYLRRVNELLMR

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=695, Percent_Identity=37.6978417266187, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI4507677, Length=693, Percent_Identity=37.5180375180375, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI155722983, Length=656, Percent_Identity=34.6036585365854, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=36.231884057971, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=36.231884057971, Blast_Score=261, Evalue=1e-69,
Organism=Escherichia coli, GI1786679, Length=639, Percent_Identity=52.8951486697966, Blast_Score=696, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=674, Percent_Identity=37.3887240356083, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17542208, Length=708, Percent_Identity=37.1468926553672, Blast_Score=400, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=669, Percent_Identity=34.5291479820628, Blast_Score=325, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI115535167, Length=451, Percent_Identity=37.2505543237251, Blast_Score=258, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=678, Percent_Identity=39.0855457227139, Blast_Score=432, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6325016, Length=682, Percent_Identity=38.7096774193548, Blast_Score=430, Evalue=1e-121,
Organism=Drosophila melanogaster, GI17647529, Length=691, Percent_Identity=36.4688856729378, Blast_Score=431, Evalue=1e-120,
Organism=Drosophila melanogaster, GI21357739, Length=688, Percent_Identity=37.3546511627907, Blast_Score=404, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24586016, Length=669, Percent_Identity=34.2301943198804, Blast_Score=345, Evalue=6e-95,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_PSYCK (Q1Q978)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_581259.1
- ProteinModelPortal:   Q1Q978
- STRING:   Q1Q978
- GeneID:   4034983
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_1998
- NMPDR:   fig|335284.3.peg.1714
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q1Q978
- ProtClustDB:   PRK05218
- BioCyc:   PCRY335284:PCRYO_1998-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 74748; Mature: 74616

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELNPVDNQKVDSINVDKSSPELKKHTFEAEVAQLLHLVTHSLYSNSDIFVRELVSNAS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DACDKLRFEATNDDSLYEDDGELKIRIAVDEDAKTITFTDNGIGMNEADAIENLGTIAKS
HHHHHCEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
GTKAFLDKLSESQKQDGQLIGQFGVGFYSGFIVADTISVETRKAGEPADKGVRWVSDGTG
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHCCEEEECCCC
SFTVEPITKETRGTAITLHLKEQYSEGEESYLDRGKIKQLVNKYSDHISLPIQMRKEVWQ
CEEECCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
EDEVEEGSDTPANGQMVLTDEWETINKASALWTRSASEIEDEEYIDFYKNITYDMDAPLA
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCCCCCCCE
WTHNRVEGRVQYTQLLYIPKKAPVDLYTREQQHGLKLYVKRVFIMDEAEQLLPMYLRFVK
ECCCCCCCEEEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIDSADLPLNVSRELLQESRDVKSIRDGNARRILTLLASLANSEDSDKQEKFAQFYAEF
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GDVIKEGVGEDMGNQERIAKLLRYATSTQDSVTTSFEDYKARMKEGQKAIYYLTADNLAA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCHHH
AKNSPQLELFKKKGIEVILMTSRVDEWAMNFLTSFDETPLQNIAKGAVDLGDLQDEAEKA
CCCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHH
EAEKAQETMKPIVDKLKTALGERAKDVKVSTRLVDSPACLVVGEGELSPQMIQMLKQMGQ
HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHEEECCCCEEEEECCCCCHHHHHHHHHHCC
DVPESKPTLEVNPDHPLIKKLESSEQSAEDFDKLAQVIFDQALLADGGQLDDPAAYLRRV
CCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
NELLMR
HHHHCC
>Mature Secondary Structure 
SELNPVDNQKVDSINVDKSSPELKKHTFEAEVAQLLHLVTHSLYSNSDIFVRELVSNAS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DACDKLRFEATNDDSLYEDDGELKIRIAVDEDAKTITFTDNGIGMNEADAIENLGTIAKS
HHHHHCEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
GTKAFLDKLSESQKQDGQLIGQFGVGFYSGFIVADTISVETRKAGEPADKGVRWVSDGTG
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHCCEEEECCCC
SFTVEPITKETRGTAITLHLKEQYSEGEESYLDRGKIKQLVNKYSDHISLPIQMRKEVWQ
CEEECCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
EDEVEEGSDTPANGQMVLTDEWETINKASALWTRSASEIEDEEYIDFYKNITYDMDAPLA
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCCCCCCCE
WTHNRVEGRVQYTQLLYIPKKAPVDLYTREQQHGLKLYVKRVFIMDEAEQLLPMYLRFVK
ECCCCCCCEEEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIDSADLPLNVSRELLQESRDVKSIRDGNARRILTLLASLANSEDSDKQEKFAQFYAEF
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GDVIKEGVGEDMGNQERIAKLLRYATSTQDSVTTSFEDYKARMKEGQKAIYYLTADNLAA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCHHH
AKNSPQLELFKKKGIEVILMTSRVDEWAMNFLTSFDETPLQNIAKGAVDLGDLQDEAEKA
CCCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHH
EAEKAQETMKPIVDKLKTALGERAKDVKVSTRLVDSPACLVVGEGELSPQMIQMLKQMGQ
HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHEEECCCCEEEEECCCCCHHHHHHHHHHCC
DVPESKPTLEVNPDHPLIKKLESSEQSAEDFDKLAQVIFDQALLADGGQLDDPAAYLRRV
CCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
NELLMR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA