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The map label for this gene is silP [H]

Identifier: 93006601

GI number: 93006601

Start: 2197752

End: 2200196

Strand: Reverse

Name: silP [H]

Synonym: Pcryo_1777

Alternate gene names: 93006601

Gene position: 2200196-2197752 (Counterclockwise)

Preceding gene: 93006602

Following gene: 93006600

Centisome position: 71.9

GC content: 48.71

Gene sequence:

>2445_bases
ATGAATCCTAATAATAGCGATAAAAAGAATGGCCATAGTGGTTTAGAGTCAAACAATACTAACCAAGCCCATACTACCTT
CAAAGAGTATAACCAAGTGCCAGCTGATTATAATGGCGCCGTTTATACCTGTCCGATGCATCCCGAAGTGAGAGATGTTG
AAAAAAGCGACTGCCCAATATGTGGTATGTTCCTCAAACCTGAAGACGAGGTTACAGATGAAGACAGTCATTCACATTGT
CATGGCAAAGATACTGACCGTACTAAGGTAAAATCTGTCAAAGGCGGCAAATACGACAAAGTGCCAGCTGATTATAGCGG
TACAGTCTATATTTGTCCGATGCATTCAGAAGTCAGAGATGTGAAGAATAGCGGCTGTCCGATATGCGGCATGACGCTTG
AACCAGAGATGGCTACTATTGGTGAGGAGGACACCTCAGAGCTCGACGATATGACACGCCGTTTCTGGATTTGTACGGTG
CTTACCATACCGCTATTTCTGTATGCTATGAGTGACATGGTAGGTCTAAGCTTAGACAACCTTGGACAAGGTGATATCTC
TGGACAGATCGCTCAGTGGATTCAGCTAGCGCTTGCAACACCAGTGGTGTTATGGGGAGGCGCACCATTCTTCGTCCGTG
GCTGGCAATCAATAAAAAGCCGAAACCTGAACATGTTCACTTTGATTGCAGTTGGTGTAGGTGCAGCCTTTGGTTTCAGT
CTGGTAGCAACCTTCCTTCCGGATGTTTTTCCAGACAGCTTCAGGGACGCCACTGGCCAAGTAGGGGTGTACTACGAAGC
GGCAGCGGTCATTGTGACCTTAGTGCTATTGGGTCAAGTGTTAGAGCTCAAAGCCAGAAGTCAGACCTCAGGAGCAATCC
GTGCGTTACTAGAGCTGGCACCACCAACGGCAAGACGTGTGGATGAGAACGATGTCGAGACCGAAGTATCACTTGACGAA
GTGATCAGCGGCGACAGATTGCGAGTCAAGCCAGGAGAAAAGCTTCCTGTAGACGGCACGGTACTTGATGGTAGTAGTAG
CATTGATGAATCGATGGTGACTGGTGAACCCATCCCAGTGTTAAAGGCACAAGGGGATACGGTCACCGGCGGCACAGTCA
ACGGTACTGGGACACTACTGATCAAAGCAGTTAACGTTGGTGATGATACCGTATTGTCCAAGATCGTCAAGATGGTTGCT
GAAGCCCAGCGCAGTCGCGCGCCAATACAGAAACTGGTTGATAAGGTAGCTGGATGGTTCGTGCCCATCGTACTTATTTG
CTCTGTCATTACCTTTATTGTCTGGGCGATATTTGGGCCTACGCCTGCAATGGCTTTTGCGCTGGTCAATGCTATCGCTG
TATTAATCATTGCCTGCCCTTGTGCGTTAGGGCTCGCCACACCGATGTCGATTATGGTGGGTACTGGTAAAGGAGCACAA
AATGGCGTGCTTATCAAGAATGCTGAAGCGTTAGAAAGTATGGAAAAAGTCGACACCATCGTTGTCGATAAAACCGGAAC
GCTGACAGCAGGCAAACCAGAGCTTACCGCTATCGAAGCGCTTGGCGGCTTAGACGAGGATGAGATGCTTATACTTGTCG
CAGCGGTAGAGACTGCCAGCGAACATCCTCTGGCAGAAGCTATTGTCAATGCAGCAAAGGCAAAATCTCTCGATATGGTT
AAGGCAAGCGATTTTAGTTCAACTACCGGTGAAGGCGCGCAGGCGCTGGTCAATGGCAAGCAAGTCGCCGTAGGCAACTC
AAAATTCATGCAACGCCTCAATAGTTTTGATAGTACGCTTTTAGAACGCGCCGACAAACGCAGGAAGGACGGTGAAACTG
TTATGTTTGTCGCAGTAGATGGGCAAGCTGCTGGTCTCATATCGGTCGCTGATCCGATCAAGCCGAGTACCAGTGAGGCA
ATATCGCTATTACACAAAGCTGGACTGCGGGTAGTCATGCTGACAGGTGATAATGAGATAACGGCTAGAGCGGTTGCTAG
TAAGTTAAAGATTGATGAGGTACATGCTGACGTCTCTCCAGAAGACAAAAACCGTATCATCAAAGAGTTGCAAAGTAGTG
GCAAGGTTGTGGCTATGGCGGGTGACGGTATTAACGATGCTCCCGCTCTTGCCCAAGCAGATGTCGGCATCGCTATGGGC
ACAGGAACAGATGTGGCCATGGAGAGTGCTGGCATTACGCTAGTGAAGGGTGACCTGATGGGGATTGTAAGAGCCCATAA
ACTGAGCCATTCTACGATGCGCAATATCAGACAAAACCTGTTCTTTGCATTTATATACAACGCCCTTGGTGTACCAATTG
CGGCAGGTGTGCTGTATCCGTTCTTCGGGATTTTACTCAGTCCAATGATAGCGGCGGCGGCTATGAGTCTCTCGTCAGTA
TCTGTTATTGGTAACGCGCTGCGGTTGCGCCGTTTGAAGCTGTAA

Upstream 100 bases:

>100_bases
AAAATTAAGATTTTATCAAATAGTAATCATGATAACGGGCATCTCTTAACCATTGAATTAGAGCGCAATCTTTACTCAAT
ATAAGTGAAGGAGTTATCTG

Downstream 100 bases:

>100_bases
TTTTGGTACGGTGAAGAGGGTTTTAAAGCACACATACACATACTGGTCTTATCAAGGCCTAAGATATAAGGATACCGTTA
TGGGCAGTTTTTCTATTACA

Product: heavy metal translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 814; Mature: 814

Protein sequence:

>814_residues
MNPNNSDKKNGHSGLESNNTNQAHTTFKEYNQVPADYNGAVYTCPMHPEVRDVEKSDCPICGMFLKPEDEVTDEDSHSHC
HGKDTDRTKVKSVKGGKYDKVPADYSGTVYICPMHSEVRDVKNSGCPICGMTLEPEMATIGEEDTSELDDMTRRFWICTV
LTIPLFLYAMSDMVGLSLDNLGQGDISGQIAQWIQLALATPVVLWGGAPFFVRGWQSIKSRNLNMFTLIAVGVGAAFGFS
LVATFLPDVFPDSFRDATGQVGVYYEAAAVIVTLVLLGQVLELKARSQTSGAIRALLELAPPTARRVDENDVETEVSLDE
VISGDRLRVKPGEKLPVDGTVLDGSSSIDESMVTGEPIPVLKAQGDTVTGGTVNGTGTLLIKAVNVGDDTVLSKIVKMVA
EAQRSRAPIQKLVDKVAGWFVPIVLICSVITFIVWAIFGPTPAMAFALVNAIAVLIIACPCALGLATPMSIMVGTGKGAQ
NGVLIKNAEALESMEKVDTIVVDKTGTLTAGKPELTAIEALGGLDEDEMLILVAAVETASEHPLAEAIVNAAKAKSLDMV
KASDFSSTTGEGAQALVNGKQVAVGNSKFMQRLNSFDSTLLERADKRRKDGETVMFVAVDGQAAGLISVADPIKPSTSEA
ISLLHKAGLRVVMLTGDNEITARAVASKLKIDEVHADVSPEDKNRIIKELQSSGKVVAMAGDGINDAPALAQADVGIAMG
TGTDVAMESAGITLVKGDLMGIVRAHKLSHSTMRNIRQNLFFAFIYNALGVPIAAGVLYPFFGILLSPMIAAAAMSLSSV
SVIGNALRLRRLKL

Sequences:

>Translated_814_residues
MNPNNSDKKNGHSGLESNNTNQAHTTFKEYNQVPADYNGAVYTCPMHPEVRDVEKSDCPICGMFLKPEDEVTDEDSHSHC
HGKDTDRTKVKSVKGGKYDKVPADYSGTVYICPMHSEVRDVKNSGCPICGMTLEPEMATIGEEDTSELDDMTRRFWICTV
LTIPLFLYAMSDMVGLSLDNLGQGDISGQIAQWIQLALATPVVLWGGAPFFVRGWQSIKSRNLNMFTLIAVGVGAAFGFS
LVATFLPDVFPDSFRDATGQVGVYYEAAAVIVTLVLLGQVLELKARSQTSGAIRALLELAPPTARRVDENDVETEVSLDE
VISGDRLRVKPGEKLPVDGTVLDGSSSIDESMVTGEPIPVLKAQGDTVTGGTVNGTGTLLIKAVNVGDDTVLSKIVKMVA
EAQRSRAPIQKLVDKVAGWFVPIVLICSVITFIVWAIFGPTPAMAFALVNAIAVLIIACPCALGLATPMSIMVGTGKGAQ
NGVLIKNAEALESMEKVDTIVVDKTGTLTAGKPELTAIEALGGLDEDEMLILVAAVETASEHPLAEAIVNAAKAKSLDMV
KASDFSSTTGEGAQALVNGKQVAVGNSKFMQRLNSFDSTLLERADKRRKDGETVMFVAVDGQAAGLISVADPIKPSTSEA
ISLLHKAGLRVVMLTGDNEITARAVASKLKIDEVHADVSPEDKNRIIKELQSSGKVVAMAGDGINDAPALAQADVGIAMG
TGTDVAMESAGITLVKGDLMGIVRAHKLSHSTMRNIRQNLFFAFIYNALGVPIAAGVLYPFFGILLSPMIAAAAMSLSSV
SVIGNALRLRRLKL
>Mature_814_residues
MNPNNSDKKNGHSGLESNNTNQAHTTFKEYNQVPADYNGAVYTCPMHPEVRDVEKSDCPICGMFLKPEDEVTDEDSHSHC
HGKDTDRTKVKSVKGGKYDKVPADYSGTVYICPMHSEVRDVKNSGCPICGMTLEPEMATIGEEDTSELDDMTRRFWICTV
LTIPLFLYAMSDMVGLSLDNLGQGDISGQIAQWIQLALATPVVLWGGAPFFVRGWQSIKSRNLNMFTLIAVGVGAAFGFS
LVATFLPDVFPDSFRDATGQVGVYYEAAAVIVTLVLLGQVLELKARSQTSGAIRALLELAPPTARRVDENDVETEVSLDE
VISGDRLRVKPGEKLPVDGTVLDGSSSIDESMVTGEPIPVLKAQGDTVTGGTVNGTGTLLIKAVNVGDDTVLSKIVKMVA
EAQRSRAPIQKLVDKVAGWFVPIVLICSVITFIVWAIFGPTPAMAFALVNAIAVLIIACPCALGLATPMSIMVGTGKGAQ
NGVLIKNAEALESMEKVDTIVVDKTGTLTAGKPELTAIEALGGLDEDEMLILVAAVETASEHPLAEAIVNAAKAKSLDMV
KASDFSSTTGEGAQALVNGKQVAVGNSKFMQRLNSFDSTLLERADKRRKDGETVMFVAVDGQAAGLISVADPIKPSTSEA
ISLLHKAGLRVVMLTGDNEITARAVASKLKIDEVHADVSPEDKNRIIKELQSSGKVVAMAGDGINDAPALAQADVGIAMG
TGTDVAMESAGITLVKGDLMGIVRAHKLSHSTMRNIRQNLFFAFIYNALGVPIAAGVLYPFFGILLSPMIAAAAMSLSSV
SVIGNALRLRRLKL

Specific function: Component of the sil cation-efflux system that confers resistance to silver [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=665, Percent_Identity=38.3458646616541, Blast_Score=427, Evalue=1e-119,
Organism=Homo sapiens, GI115529486, Length=683, Percent_Identity=37.3352855051244, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI55743073, Length=549, Percent_Identity=38.615664845173, Blast_Score=346, Evalue=7e-95,
Organism=Homo sapiens, GI28373109, Length=174, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI28373107, Length=174, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI28373113, Length=174, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI28373103, Length=174, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI28373115, Length=174, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI28373111, Length=174, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI28373105, Length=174, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI48762685, Length=182, Percent_Identity=37.9120879120879, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI48762689, Length=182, Percent_Identity=37.9120879120879, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI48762687, Length=182, Percent_Identity=37.9120879120879, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI48762691, Length=182, Percent_Identity=37.9120879120879, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI209413709, Length=216, Percent_Identity=29.1666666666667, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI24638454, Length=216, Percent_Identity=29.1666666666667, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI4502285, Length=216, Percent_Identity=29.1666666666667, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI10835220, Length=192, Percent_Identity=31.7708333333333, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI27886529, Length=192, Percent_Identity=31.7708333333333, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI118498343, Length=166, Percent_Identity=37.9518072289157, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI310128958, Length=186, Percent_Identity=32.258064516129, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI153946397, Length=240, Percent_Identity=27.9166666666667, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI297374799, Length=237, Percent_Identity=26.5822784810127, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI83700225, Length=237, Percent_Identity=26.5822784810127, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI51944966, Length=263, Percent_Identity=24.7148288973384, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI22748667, Length=256, Percent_Identity=23.046875, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI4502271, Length=256, Percent_Identity=22.65625, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI21361181, Length=256, Percent_Identity=23.046875, Blast_Score=67, Evalue=9e-11,
Organism=Homo sapiens, GI237681109, Length=256, Percent_Identity=23.046875, Blast_Score=67, Evalue=1e-10,
Organism=Escherichia coli, GI1786691, Length=668, Percent_Identity=43.7125748502994, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1789879, Length=559, Percent_Identity=35.2415026833631, Blast_Score=284, Evalue=2e-77,
Organism=Escherichia coli, GI1786914, Length=437, Percent_Identity=30.8924485125858, Blast_Score=173, Evalue=5e-44,
Organism=Escherichia coli, GI2367363, Length=630, Percent_Identity=24.2857142857143, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17556548, Length=692, Percent_Identity=39.4508670520231, Blast_Score=407, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17554158, Length=192, Percent_Identity=30.2083333333333, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71988506, Length=192, Percent_Identity=30.2083333333333, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193210130, Length=192, Percent_Identity=30.2083333333333, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71997262, Length=204, Percent_Identity=30.8823529411765, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997275, Length=204, Percent_Identity=30.8823529411765, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559224, Length=242, Percent_Identity=27.6859504132231, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71997269, Length=186, Percent_Identity=31.7204301075269, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17541776, Length=213, Percent_Identity=31.4553990610329, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17557486, Length=217, Percent_Identity=29.9539170506912, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25152707, Length=198, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999438, Length=198, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71999440, Length=198, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17557770, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32566766, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531459, Length=124, Percent_Identity=37.0967741935484, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320475, Length=659, Percent_Identity=37.4810318664643, Blast_Score=379, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6319772, Length=677, Percent_Identity=30.1329394387001, Blast_Score=297, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6325221, Length=563, Percent_Identity=24.1563055062167, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321430, Length=522, Percent_Identity=25.8620689655172, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321271, Length=627, Percent_Identity=24.2424242424242, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321432, Length=180, Percent_Identity=35.5555555555556, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320243, Length=217, Percent_Identity=30.8755760368664, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320244, Length=217, Percent_Identity=30.8755760368664, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221329854, Length=522, Percent_Identity=34.8659003831418, Blast_Score=256, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24668708, Length=167, Percent_Identity=37.7245508982036, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24668704, Length=167, Percent_Identity=37.7245508982036, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281366617, Length=167, Percent_Identity=37.7245508982036, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI161085803, Length=169, Percent_Identity=37.2781065088757, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24668696, Length=169, Percent_Identity=37.2781065088757, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136664, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24762455, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24762453, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24762447, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24762457, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24762449, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24762445, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24762451, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648582, Length=216, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553435, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553439, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362164, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553437, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553441, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648580, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648578, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648576, Length=197, Percent_Identity=26.9035532994924, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281366676, Length=267, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR007029 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase; PF04945 YHS [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 86436; Mature: 86436

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNNSDKKNGHSGLESNNTNQAHTTFKEYNQVPADYNGAVYTCPMHPEVRDVEKSDCPI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCHHCCCCCCCCE
CGMFLKPEDEVTDEDSHSHCHGKDTDRTKVKSVKGGKYDKVPADYSGTVYICPMHSEVRD
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHH
VKNSGCPICGMTLEPEMATIGEEDTSELDDMTRRFWICTVLTIPLFLYAMSDMVGLSLDN
HHCCCCCEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LGQGDISGQIAQWIQLALATPVVLWGGAPFFVRGWQSIKSRNLNMFTLIAVGVGAAFGFS
CCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
LVATFLPDVFPDSFRDATGQVGVYYEAAAVIVTLVLLGQVLELKARSQTSGAIRALLELA
HHHHHHHHCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PPTARRVDENDVETEVSLDEVISGDRLRVKPGEKLPVDGTVLDGSSSIDESMVTGEPIPV
CCHHHCCCCCCCHHHCCHHHHHCCCEEEECCCCCCCCCCEEECCCCCCCHHHHCCCCCCE
LKAQGDTVTGGTVNGTGTLLIKAVNVGDDTVLSKIVKMVAEAQRSRAPIQKLVDKVAGWF
EECCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPIVLICSVITFIVWAIFGPTPAMAFALVNAIAVLIIACPCALGLATPMSIMVGTGKGAQ
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
NGVLIKNAEALESMEKVDTIVVDKTGTLTAGKPELTAIEALGGLDEDEMLILVAAVETAS
CCEEEECHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCC
EHPLAEAIVNAAKAKSLDMVKASDFSSTTGEGAQALVNGKQVAVGNSKFMQRLNSFDSTL
CCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHH
LERADKRRKDGETVMFVAVDGQAAGLISVADPIKPSTSEAISLLHKAGLRVVMLTGDNEI
HHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCH
TARAVASKLKIDEVHADVSPEDKNRIIKELQSSGKVVAMAGDGINDAPALAQADVGIAMG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCEEEC
TGTDVAMESAGITLVKGDLMGIVRAHKLSHSTMRNIRQNLFFAFIYNALGVPIAAGVLYP
CCCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
FFGILLSPMIAAAAMSLSSVSVIGNALRLRRLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPNNSDKKNGHSGLESNNTNQAHTTFKEYNQVPADYNGAVYTCPMHPEVRDVEKSDCPI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCHHCCCCCCCCE
CGMFLKPEDEVTDEDSHSHCHGKDTDRTKVKSVKGGKYDKVPADYSGTVYICPMHSEVRD
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHH
VKNSGCPICGMTLEPEMATIGEEDTSELDDMTRRFWICTVLTIPLFLYAMSDMVGLSLDN
HHCCCCCEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LGQGDISGQIAQWIQLALATPVVLWGGAPFFVRGWQSIKSRNLNMFTLIAVGVGAAFGFS
CCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
LVATFLPDVFPDSFRDATGQVGVYYEAAAVIVTLVLLGQVLELKARSQTSGAIRALLELA
HHHHHHHHCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PPTARRVDENDVETEVSLDEVISGDRLRVKPGEKLPVDGTVLDGSSSIDESMVTGEPIPV
CCHHHCCCCCCCHHHCCHHHHHCCCEEEECCCCCCCCCCEEECCCCCCCHHHHCCCCCCE
LKAQGDTVTGGTVNGTGTLLIKAVNVGDDTVLSKIVKMVAEAQRSRAPIQKLVDKVAGWF
EECCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPIVLICSVITFIVWAIFGPTPAMAFALVNAIAVLIIACPCALGLATPMSIMVGTGKGAQ
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
NGVLIKNAEALESMEKVDTIVVDKTGTLTAGKPELTAIEALGGLDEDEMLILVAAVETAS
CCEEEECHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCC
EHPLAEAIVNAAKAKSLDMVKASDFSSTTGEGAQALVNGKQVAVGNSKFMQRLNSFDSTL
CCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHH
LERADKRRKDGETVMFVAVDGQAAGLISVADPIKPSTSEAISLLHKAGLRVVMLTGDNEI
HHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCH
TARAVASKLKIDEVHADVSPEDKNRIIKELQSSGKVVAMAGDGINDAPALAQADVGIAMG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCEEEC
TGTDVAMESAGITLVKGDLMGIVRAHKLSHSTMRNIRQNLFFAFIYNALGVPIAAGVLYP
CCCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
FFGILLSPMIAAAAMSLSSVSVIGNALRLRRLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]