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The map label for this gene is blh [H]

Identifier: 93006602

GI number: 93006602

Start: 2200856

End: 2201605

Strand: Reverse

Name: blh [H]

Synonym: Pcryo_1778

Alternate gene names: 93006602

Gene position: 2201605-2200856 (Counterclockwise)

Preceding gene: 93006603

Following gene: 93006601

Centisome position: 71.95

GC content: 48.8

Gene sequence:

>750_bases
ATGATATTTCGTCAATTGTACGAACCCCTTTCGAGCACTTATACCTATCTGTTAGGGGATGAGGATACAGGTCAAGCTAT
CCTGATTGATCCGGTCATAGCGACTATGGATCGTGACTTGGCTGAAATCCATAGATTGGGACTGGATTTGGTCTACACAG
TTGACACGCATATCCACGCAGATCACATTACTGCAGCACTAGAGATGAAGCGTGCCGTCGGTAGCAAGATCGCAGCGCCT
GCCTTTGACCGTCTACCATGTGTGGATGTCGGGCTGGAAGAAGGAACACCTTTGCAGGTTGCTGGTATTACCCTGCACCC
ATTGCATACGCCGGGACACACCGATGGTCATTTTGCGTATCTCTTTAATGAGCGGGTATTCACTGGCGATGCTTTACTTA
TCGATGGATGTGGCCGGACCGACTTCCAGAATGGCGATGCCGATGCGCTGTATAAATCTGTGCGGCAGAAACTTTTTTCT
TTACCAGACGACACGCTGGTCTATCCTGCGCACGACTACAAGGAGCGCTTTGTTTCTTCAATCGCGCAGGAAAAAAAGCG
CAATCCACGGCTTGGCGGGGACATAACACTCGAAGAATTCAAGGTCATCATGAGCAACCTAAATCTATCATATCCGAAAT
TCATTGATTATGCTGTCCCTGGCAACCAGCAGTGTGGCGTCTGCCCAGAGGATTTACCAGAAAATTTAGCCACTTACTGT
CGCCAGATGATGCAGAGCCCTCAAGGATAA

Upstream 100 bases:

>100_bases
AATGCTTTATGAATACACTATATTAGAACATAATATATAAAAAATAGGTGCAATAACCAGTGTGTTGGGCATCACCCCTT
ACCTTAGACAAGGAATAATC

Downstream 100 bases:

>100_bases
CGTTACTGATTTTAAAAGAGTCGACGTTTAACGATGGTTAATTTATCGGCTCTGATCTTGAAGAGATGTAATTAATGAGC
ATTTGATATTCCCATGCTTA

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MIFRQLYEPLSSTYTYLLGDEDTGQAILIDPVIATMDRDLAEIHRLGLDLVYTVDTHIHADHITAALEMKRAVGSKIAAP
AFDRLPCVDVGLEEGTPLQVAGITLHPLHTPGHTDGHFAYLFNERVFTGDALLIDGCGRTDFQNGDADALYKSVRQKLFS
LPDDTLVYPAHDYKERFVSSIAQEKKRNPRLGGDITLEEFKVIMSNLNLSYPKFIDYAVPGNQQCGVCPEDLPENLATYC
RQMMQSPQG

Sequences:

>Translated_249_residues
MIFRQLYEPLSSTYTYLLGDEDTGQAILIDPVIATMDRDLAEIHRLGLDLVYTVDTHIHADHITAALEMKRAVGSKIAAP
AFDRLPCVDVGLEEGTPLQVAGITLHPLHTPGHTDGHFAYLFNERVFTGDALLIDGCGRTDFQNGDADALYKSVRQKLFS
LPDDTLVYPAHDYKERFVSSIAQEKKRNPRLGGDITLEEFKVIMSNLNLSYPKFIDYAVPGNQQCGVCPEDLPENLATYC
RQMMQSPQG
>Mature_249_residues
MIFRQLYEPLSSTYTYLLGDEDTGQAILIDPVIATMDRDLAEIHRLGLDLVYTVDTHIHADHITAALEMKRAVGSKIAAP
AFDRLPCVDVGLEEGTPLQVAGITLHPLHTPGHTDGHFAYLFNERVFTGDALLIDGCGRTDFQNGDADALYKSVRQKLFS
LPDDTLVYPAHDYKERFVSSIAQEKKRNPRLGGDITLEEFKVIMSNLNLSYPKFIDYAVPGNQQCGVCPEDLPENLATYC
RQMMQSPQG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=235, Percent_Identity=45.9574468085106, Blast_Score=208, Evalue=3e-54,
Organism=Homo sapiens, GI94538320, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI94538322, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI21703352, Length=174, Percent_Identity=32.183908045977, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI116642887, Length=174, Percent_Identity=32.183908045977, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI46361987, Length=171, Percent_Identity=32.1637426900585, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI14150041, Length=171, Percent_Identity=32.1637426900585, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787158, Length=203, Percent_Identity=32.0197044334975, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786406, Length=82, Percent_Identity=42.6829268292683, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538952, Length=227, Percent_Identity=43.6123348017621, Blast_Score=187, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17536925, Length=183, Percent_Identity=26.775956284153, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221330176, Length=238, Percent_Identity=47.0588235294118, Blast_Score=208, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21356335, Length=172, Percent_Identity=30.2325581395349, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667711, Length=172, Percent_Identity=30.2325581395349, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667703, Length=172, Percent_Identity=30.2325581395349, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 27732; Mature: 27732

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFRQLYEPLSSTYTYLLGDEDTGQAILIDPVIATMDRDLAEIHRLGLDLVYTVDTHIHA
CCHHHHHHHHHHCEEEEECCCCCCCEEEECHHHHHHCHHHHHHHHCCCEEEEEECCEEEH
DHITAALEMKRAVGSKIAAPAFDRLPCVDVGLEEGTPLQVAGITLHPLHTPGHTDGHFAY
HHHHHHHHHHHHHCCHHCCCCCCCCCCEECCCCCCCCEEEECEEEEECCCCCCCCCEEEE
LFNERVFTGDALLIDGCGRTDFQNGDADALYKSVRQKLFSLPDDTLVYPAHDYKERFVSS
EECCEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHH
IAQEKKRNPRLGGDITLEEFKVIMSNLNLSYPKFIDYAVPGNQQCGVCPEDLPENLATYC
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCHHHHHHHHHHHH
RQMMQSPQG
HHHHHCCCC
>Mature Secondary Structure
MIFRQLYEPLSSTYTYLLGDEDTGQAILIDPVIATMDRDLAEIHRLGLDLVYTVDTHIHA
CCHHHHHHHHHHCEEEEECCCCCCCEEEECHHHHHHCHHHHHHHHCCCEEEEEECCEEEH
DHITAALEMKRAVGSKIAAPAFDRLPCVDVGLEEGTPLQVAGITLHPLHTPGHTDGHFAY
HHHHHHHHHHHHHCCHHCCCCCCCCCCEECCCCCCCCEEEECEEEEECCCCCCCCCEEEE
LFNERVFTGDALLIDGCGRTDFQNGDADALYKSVRQKLFSLPDDTLVYPAHDYKERFVSS
EECCEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHH
IAQEKKRNPRLGGDITLEEFKVIMSNLNLSYPKFIDYAVPGNQQCGVCPEDLPENLATYC
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCHHHHHHHHHHHH
RQMMQSPQG
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]