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The map label for this gene is pyrH [H]

Identifier: 93006538

GI number: 93006538

Start: 2121365

End: 2122090

Strand: Reverse

Name: pyrH [H]

Synonym: Pcryo_1714

Alternate gene names: 93006538

Gene position: 2122090-2121365 (Counterclockwise)

Preceding gene: 93006539

Following gene: 93006537

Centisome position: 69.35

GC content: 45.59

Gene sequence:

>726_bases
ATGTCTGACAAAAACCCGCGTTATTCTCGTATCTTGCTAAAACTTTCTGGTGAAGCCTTAGCGGGTACGAAAGATATGGG
TATTGATACCGAAGTGCTCGATAAGATGAGCTTATCTATCGCCCATTTGCGCGGGCTTGGTGTCCAAGTGGGTATCGTGG
TCGGTGGTGGTAACTTATATCGCGGCGCTCAATTACAAAAAGAGGGTTTGGTCGGCCGCGTCACTGGCGATCAAATGGGC
ATGCTTGCAACCGTCATGAATGGCCTTGCAATGCGTGATGCTCTTGAGCGCCGCAATATCAAAACGCGCCTAATGTCAGC
CCTGCCGATTGGTGAAGTCACTGAAAGTTATAGCAGCCGTAATGCGATTCGTTATCTTAAAAATGGCGAAGTATGTATCT
TTGTCGCGGGTACGGGCAACCCTTTCTTTACTACTGATACGGCTGCTTGCTTACGTGGTATTGAAATCGAAGCAGGCTTG
ATTCTAAAAGCGACCAAAGTAGATGGTGTTTATGATAAAGACCCAAGCCTACATAGCGATGCAGTAAAATATGATGGTCT
GACCTTTGATGAGGTGTTAGAGCAAAAGCTTGGAGTTATGGACTTGACTGCCATCGCATTATGTCGTGAGCACGATGTGC
CATTACAAGTCTTTGATATGAATAAGCCTAATGCTTTATTAAATGTTGTGATGGGCGAGAATGAAGGCACACGCGTCTAT
CATTAA

Upstream 100 bases:

>100_bases
CTTATCCTTAAGTTGGGCAATGCCGTCAAGTCTCAAAGTAAACTCTATTTGTATATTACCGATAACTTTAATTATAATTC
AATACTGACAAGGTGACCTC

Downstream 100 bases:

>100_bases
TATCGTACCCAAAAATATGATAAAAGATAGGCAGAAGTAAGACAGCTGCTTATCTGTGAAAACACCTGAATAGTTTTTAT
AATAAACAATAAATGATTTG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSDKNPRYSRILLKLSGEALAGTKDMGIDTEVLDKMSLSIAHLRGLGVQVGIVVGGGNLYRGAQLQKEGLVGRVTGDQMG
MLATVMNGLAMRDALERRNIKTRLMSALPIGEVTESYSSRNAIRYLKNGEVCIFVAGTGNPFFTTDTAACLRGIEIEAGL
ILKATKVDGVYDKDPSLHSDAVKYDGLTFDEVLEQKLGVMDLTAIALCREHDVPLQVFDMNKPNALLNVVMGENEGTRVY
H

Sequences:

>Translated_241_residues
MSDKNPRYSRILLKLSGEALAGTKDMGIDTEVLDKMSLSIAHLRGLGVQVGIVVGGGNLYRGAQLQKEGLVGRVTGDQMG
MLATVMNGLAMRDALERRNIKTRLMSALPIGEVTESYSSRNAIRYLKNGEVCIFVAGTGNPFFTTDTAACLRGIEIEAGL
ILKATKVDGVYDKDPSLHSDAVKYDGLTFDEVLEQKLGVMDLTAIALCREHDVPLQVFDMNKPNALLNVVMGENEGTRVY
H
>Mature_240_residues
SDKNPRYSRILLKLSGEALAGTKDMGIDTEVLDKMSLSIAHLRGLGVQVGIVVGGGNLYRGAQLQKEGLVGRVTGDQMGM
LATVMNGLAMRDALERRNIKTRLMSALPIGEVTESYSSRNAIRYLKNGEVCIFVAGTGNPFFTTDTAACLRGIEIEAGLI
LKATKVDGVYDKDPSLHSDAVKYDGLTFDEVLEQKLGVMDLTAIALCREHDVPLQVFDMNKPNALLNVVMGENEGTRVYH

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=238, Percent_Identity=60.9243697478992, Blast_Score=291, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26164; Mature: 26032

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKNPRYSRILLKLSGEALAGTKDMGIDTEVLDKMSLSIAHLRGLGVQVGIVVGGGNLY
CCCCCCCCEEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
RGAQLQKEGLVGRVTGDQMGMLATVMNGLAMRDALERRNIKTRLMSALPIGEVTESYSSR
CCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
NAIRYLKNGEVCIFVAGTGNPFFTTDTAACLRGIEIEAGLILKATKVDGVYDKDPSLHSD
CCEEEECCCCEEEEEEECCCCEEECCHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCC
AVKYDGLTFDEVLEQKLGVMDLTAIALCREHDVPLQVFDMNKPNALLNVVMGENEGTRVY
CEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCC
H
C
>Mature Secondary Structure 
SDKNPRYSRILLKLSGEALAGTKDMGIDTEVLDKMSLSIAHLRGLGVQVGIVVGGGNLY
CCCCCCCEEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
RGAQLQKEGLVGRVTGDQMGMLATVMNGLAMRDALERRNIKTRLMSALPIGEVTESYSSR
CCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
NAIRYLKNGEVCIFVAGTGNPFFTTDTAACLRGIEIEAGLILKATKVDGVYDKDPSLHSD
CCEEEECCCCEEEEEEECCCCEEECCHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCC
AVKYDGLTFDEVLEQKLGVMDLTAIALCREHDVPLQVFDMNKPNALLNVVMGENEGTRVY
CEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA