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The map label for this gene is frr [H]

Identifier: 93006537

GI number: 93006537

Start: 2120684

End: 2121238

Strand: Reverse

Name: frr [H]

Synonym: Pcryo_1713

Alternate gene names: 93006537

Gene position: 2121238-2120684 (Counterclockwise)

Preceding gene: 93006538

Following gene: 93006536

Centisome position: 69.32

GC content: 43.96

Gene sequence:

>555_bases
ATGATTCAAGAAATTAAGCAAGACGGCGAAGCGCGCATGCAAAAAACCTTGGAAGCGCTTGAAAGCACCTTTAGTAAAGT
TCGTACGGGTCGCGCGCATCCAGGTATGTTGACAGGCGTGATGGTCAGCTACTATGGTTCGCCTACGCCTTTAAATCAAG
TAGCGAGTGTTAACGTTGAAGATTCGCGTACGCTACTGGTACAGCCATTTGACCGTACCATGGTGCAAGCGATTGATAAA
GCTATCCGCGAAGCAGATTTGGGTCTTAATCCAATGACTGCTGATGTGATTCGTGTTCCCATGCCAGCATTGACAGAAGA
AACTCGAAAAGATATGCAAAAATTGGCACGTGGCGAAGCAGAAAACAGCCGTGTTTCTATTCGTAATATCCGCCGTGATA
TGATGAATGACATCAAAGAGTTAGCAAAAGAAAAAGAGATTTCTGAAGACGACGAGCGCCGCGCCAGTGATGACATTCAA
AAAATCACTGACAAATATATTGAAACAATCGATAGCCGCTTAAGCAAAAAAGAAACCGATTTGATGGCAGTATAA

Upstream 100 bases:

>100_bases
ATAGGCAGAAGTAAGACAGCTGCTTATCTGTGAAAACACCTGAATAGTTTTTATAATAAACAATAAATGATTTGTCGGTA
GCGATAAATAAGGATACCTC

Downstream 100 bases:

>100_bases
GTACATTTTTCTGCTGTCAAAAATGATGCGCTATCAATATTTTATATAACAAGTCGCTAAAAACAAACAGCCAATATCAA
AGTGCTATTGGCTGTTTGTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIQEIKQDGEARMQKTLEALESTFSKVRTGRAHPGMLTGVMVSYYGSPTPLNQVASVNVEDSRTLLVQPFDRTMVQAIDK
AIREADLGLNPMTADVIRVPMPALTEETRKDMQKLARGEAENSRVSIRNIRRDMMNDIKELAKEKEISEDDERRASDDIQ
KITDKYIETIDSRLSKKETDLMAV

Sequences:

>Translated_184_residues
MIQEIKQDGEARMQKTLEALESTFSKVRTGRAHPGMLTGVMVSYYGSPTPLNQVASVNVEDSRTLLVQPFDRTMVQAIDK
AIREADLGLNPMTADVIRVPMPALTEETRKDMQKLARGEAENSRVSIRNIRRDMMNDIKELAKEKEISEDDERRASDDIQ
KITDKYIETIDSRLSKKETDLMAV
>Mature_184_residues
MIQEIKQDGEARMQKTLEALESTFSKVRTGRAHPGMLTGVMVSYYGSPTPLNQVASVNVEDSRTLLVQPFDRTMVQAIDK
AIREADLGLNPMTADVIRVPMPALTEETRKDMQKLARGEAENSRVSIRNIRRDMMNDIKELAKEKEISEDDERRASDDIQ
KITDKYIETIDSRLSKKETDLMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=8e-16,
Organism=Homo sapiens, GI291042689, Length=136, Percent_Identity=31.6176470588235, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=56.8306010928962, Blast_Score=217, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24661488, Length=180, Percent_Identity=25.5555555555556, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20859; Mature: 20859

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQEIKQDGEARMQKTLEALESTFSKVRTGRAHPGMLTGVMVSYYGSPTPLNQVASVNVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCC
DSRTLLVQPFDRTMVQAIDKAIREADLGLNPMTADVIRVPMPALTEETRKDMQKLARGEA
CCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
ENSRVSIRNIRRDMMNDIKELAKEKEISEDDERRASDDIQKITDKYIETIDSRLSKKETD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAV
HHCC
>Mature Secondary Structure
MIQEIKQDGEARMQKTLEALESTFSKVRTGRAHPGMLTGVMVSYYGSPTPLNQVASVNVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCC
DSRTLLVQPFDRTMVQAIDKAIREADLGLNPMTADVIRVPMPALTEETRKDMQKLARGEA
CCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
ENSRVSIRNIRRDMMNDIKELAKEKEISEDDERRASDDIQKITDKYIETIDSRLSKKETD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA