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The map label for this gene is uppS [H]

Identifier: 93006536

GI number: 93006536

Start: 2119667

End: 2120425

Strand: Reverse

Name: uppS [H]

Synonym: Pcryo_1712

Alternate gene names: 93006536

Gene position: 2120425-2119667 (Counterclockwise)

Preceding gene: 93006537

Following gene: 93006535

Centisome position: 69.3

GC content: 46.25

Gene sequence:

>759_bases
ATGTCTATGTCAGAGAATTTAGCTCCAGCCCTTCTTCCACGCCATATCGCTGTTATTATGGACGGCAATAACCGCTATGG
TAAAGTCCATAATTTAGGCAAAGGTCAGGGGCATATCGCTGGCAAAGATGCGCTAGACCCTATTGTTGAGTATTGCGTCA
GTACAGGTATTGAGGTTTTGACCGTCTTTGCCTTTTCCAGTGAGAATTGGCAGCGCCCACCGACTGAAGTGGCATTGCTG
ATGCATTTGCTGAGCTTAACCATCAATGAGCAGATGCCTCGTATGGTTAAGTACCGTATTCGTTTGCGTTTTATCGGCGA
TCGCAGTCAGCTTAGTGATGATTTGCAATTATTGATGGCAGATGCTGAAGCAAAAACGGCTGATTTTGATGCTATGACAT
TGGTCATCGCCATCAGTTACGGTGGACAGTGGGATATCGCTCATGCAGCAAAGCAGCTATTACAGCAAGTGCAGGCAGGT
CAGTTATCAATCGATGATATTGATAAGGAAAAACTTGGAGAGTATGTGCAATTGGCAGATGCACCAGAAGTAGACATGCT
GATACGTACTGGCGGCGAGTACCGTCTCTCCAACTTCTTATTGTGGCAGTCAGCCTATGCAGAGCTGTTCTTTACCCCAA
CATTGTGGCCAGATTTTAGCGTCGATGAGCTAGCAGCAATGCTAGAGGATTTTGCTCAACGTCAACGCCGCTTTGGCAAA
ACCAGCGAACAAATAGTGACGGCTCAGCAAATATCTTAG

Upstream 100 bases:

>100_bases
CACTTTATATGAATCTTTTTATATAAATTATGAGTTAGGGTTTTTATAAAGTATGGCGCGCGTTATGATTATTTTACCTA
AACAACAAGCAAGTTAGCCT

Downstream 100 bases:

>100_bases
AGGTCATGTTAAGAGCATTAGACGACTTTTGTCAATTTGGAGCACTTTCAATAGCGTGCGTCACTATCAATACGCTATTA
TAGTCAGCAGCTGGCTATGA

Product: undecaprenyl diphosphate synthase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSMSENLAPALLPRHIAVIMDGNNRYGKVHNLGKGQGHIAGKDALDPIVEYCVSTGIEVLTVFAFSSENWQRPPTEVALL
MHLLSLTINEQMPRMVKYRIRLRFIGDRSQLSDDLQLLMADAEAKTADFDAMTLVIAISYGGQWDIAHAAKQLLQQVQAG
QLSIDDIDKEKLGEYVQLADAPEVDMLIRTGGEYRLSNFLLWQSAYAELFFTPTLWPDFSVDELAAMLEDFAQRQRRFGK
TSEQIVTAQQIS

Sequences:

>Translated_252_residues
MSMSENLAPALLPRHIAVIMDGNNRYGKVHNLGKGQGHIAGKDALDPIVEYCVSTGIEVLTVFAFSSENWQRPPTEVALL
MHLLSLTINEQMPRMVKYRIRLRFIGDRSQLSDDLQLLMADAEAKTADFDAMTLVIAISYGGQWDIAHAAKQLLQQVQAG
QLSIDDIDKEKLGEYVQLADAPEVDMLIRTGGEYRLSNFLLWQSAYAELFFTPTLWPDFSVDELAAMLEDFAQRQRRFGK
TSEQIVTAQQIS
>Mature_251_residues
SMSENLAPALLPRHIAVIMDGNNRYGKVHNLGKGQGHIAGKDALDPIVEYCVSTGIEVLTVFAFSSENWQRPPTEVALLM
HLLSLTINEQMPRMVKYRIRLRFIGDRSQLSDDLQLLMADAEAKTADFDAMTLVIAISYGGQWDIAHAAKQLLQQVQAGQ
LSIDDIDKEKLGEYVQLADAPEVDMLIRTGGEYRLSNFLLWQSAYAELFFTPTLWPDFSVDELAAMLEDFAQRQRRFGKT
SEQIVTAQQIS

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=212, Percent_Identity=36.3207547169811, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI45580742, Length=212, Percent_Identity=36.3207547169811, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1786371, Length=239, Percent_Identity=46.4435146443515, Blast_Score=227, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI71993029, Length=251, Percent_Identity=32.6693227091633, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319474, Length=230, Percent_Identity=35.6521739130435, Blast_Score=125, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6323748, Length=223, Percent_Identity=32.2869955156951, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI18857969, Length=220, Percent_Identity=33.1818181818182, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28294; Mature: 28163

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSENLAPALLPRHIAVIMDGNNRYGKVHNLGKGQGHIAGKDALDPIVEYCVSTGIEVL
CCCCCCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEE
TVFAFSSENWQRPPTEVALLMHLLSLTINEQMPRMVKYRIRLRFIGDRSQLSDDLQLLMA
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHH
DAEAKTADFDAMTLVIAISYGGQWDIAHAAKQLLQQVQAGQLSIDDIDKEKLGEYVQLAD
CCCCCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
APEVDMLIRTGGEYRLSNFLLWQSAYAELFFTPTLWPDFSVDELAAMLEDFAQRQRRFGK
CCCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
TSEQIVTAQQIS
CHHHHHHHHCCC
>Mature Secondary Structure 
SMSENLAPALLPRHIAVIMDGNNRYGKVHNLGKGQGHIAGKDALDPIVEYCVSTGIEVL
CCCCCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEE
TVFAFSSENWQRPPTEVALLMHLLSLTINEQMPRMVKYRIRLRFIGDRSQLSDDLQLLMA
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHH
DAEAKTADFDAMTLVIAISYGGQWDIAHAAKQLLQQVQAGQLSIDDIDKEKLGEYVQLAD
CCCCCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
APEVDMLIRTGGEYRLSNFLLWQSAYAELFFTPTLWPDFSVDELAAMLEDFAQRQRRFGK
CCCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
TSEQIVTAQQIS
CHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA