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The map label for this gene is obgE [H]

Identifier: 93006507

GI number: 93006507

Start: 2071242

End: 2072459

Strand: Reverse

Name: obgE [H]

Synonym: Pcryo_1683

Alternate gene names: 93006507

Gene position: 2072459-2071242 (Counterclockwise)

Preceding gene: 93006508

Following gene: 93006506

Centisome position: 67.73

GC content: 46.72

Gene sequence:

>1218_bases
ATGCGATTTATTGATGAAGCCGTCGTAACGGTAAAAGCAGGTGACGGTGGTAACGGAATCGCCAGTTTTCGCCGAGAAAA
ATATGTCCCGCGCGGTGGTCCTGATGGTGGTGATGGTGGCAAGGGCGGCGATGTTTATGTCATTGCAGAGGATAATACCA
ACACCTTAGTTGACTATCGTTATACCCGTCGCCACGACGCTATGCGTGCTGAGAACGGTCATAGTAGAAACTGTTCAGGC
AAAGGCTCTGATGACCTTTTCTTACCAGTGCCTATTGGTACGACGGTCGTTGATACCGAGACAGATGAAGTATTGGGTGA
TTTGATTGAAATTGGTCAGACTTTACTGATTGCCAAAGGTGGCGATGGTGGTTTGGGTAATACCCATTTCAAAAGCTCTA
CCAACCAAGCGCCGCGTAAAGCGACGTCAGGTTTTGAAGGTGAGCTAAAAGTTCTTAAGTTTGAGCTAAAAGTAGTGGCT
GATGTTGGCTTAATTGGTTTACCTAACGCAGGAAAATCGACCTTTATCCGCCAAGTCTCTGCTGCTAGACCAAAAGTAGC
TGACTATCCATTTACCACGCTGGTTCCTAATCTGGGTGTGGTTGATATTGGTCGTCATCGCTCTTTTGTTATGGCCGATA
TTCCAGGTTTGATTGAAGGTGCCTCAGAAGGTGCTGGACTTGGTATTCGCTTTTTAAAGCATGTCGCTCGTACGCGTCGT
CTGTTACACTTGGTTGATATCAAGCCTATCGATGGCAGCGACCCGGTCGAAAACGCTCGCGTTATCTTAAATGAGCTTGA
GCGTTTTTCACCTGAATTGGCCAATTTGCCACAGATTTTGGTATTAAACAAAATCGATCAGGTGCCTGAAGAAGAGTTAA
ATGAGCTTTGTACCCATATTGTGGCAGAGCTTGGCTGGACAGGTATTGTTTTCCGTACCGCCACCTTAACAGGTGAGGGT
GTTGATGCTATCAAGTACCACTTGATGAATGAGATTGAGCGTGAACGCGAACGTGAAATCGAAGATCCTATCTTTGCTGA
TGCACAAAAAGCACGATTTGAGCGTTTAGAGGCAGAAGTTCGTCTAAACACTGAAGCCCAGCGTGAAGCGTATCGTGCTG
CTCGTAAAGCGGCGCGTGAAGGTACGGATTTGTCGGATGACGATTTTGATGATAGCGATGACGATGATGATGGCGTCGAA
GTGGTTTACGCCCCTTAA

Upstream 100 bases:

>100_bases
CGAAAGTCTGCCATTTTTTTAAAAGATAACTATAGGCAAAAGAAGCAGTCTATGACTGTCATTAAGCTTATAAACTAGAG
TGTAAATAAAGGAAAGTAAG

Downstream 100 bases:

>100_bases
TCTGATTGGTCTTTGCACATATTTTTTAGATGTATCCCCATGATTAATTTACCATAGCAACAGGAGTTTATATGGCAGTT
GGCATAGAGAACACGATAGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRFIDEAVVTVKAGDGGNGIASFRREKYVPRGGPDGGDGGKGGDVYVIAEDNTNTLVDYRYTRRHDAMRAENGHSRNCSG
KGSDDLFLPVPIGTTVVDTETDEVLGDLIEIGQTLLIAKGGDGGLGNTHFKSSTNQAPRKATSGFEGELKVLKFELKVVA
DVGLIGLPNAGKSTFIRQVSAARPKVADYPFTTLVPNLGVVDIGRHRSFVMADIPGLIEGASEGAGLGIRFLKHVARTRR
LLHLVDIKPIDGSDPVENARVILNELERFSPELANLPQILVLNKIDQVPEEELNELCTHIVAELGWTGIVFRTATLTGEG
VDAIKYHLMNEIEREREREIEDPIFADAQKARFERLEAEVRLNTEAQREAYRAARKAAREGTDLSDDDFDDSDDDDDGVE
VVYAP

Sequences:

>Translated_405_residues
MRFIDEAVVTVKAGDGGNGIASFRREKYVPRGGPDGGDGGKGGDVYVIAEDNTNTLVDYRYTRRHDAMRAENGHSRNCSG
KGSDDLFLPVPIGTTVVDTETDEVLGDLIEIGQTLLIAKGGDGGLGNTHFKSSTNQAPRKATSGFEGELKVLKFELKVVA
DVGLIGLPNAGKSTFIRQVSAARPKVADYPFTTLVPNLGVVDIGRHRSFVMADIPGLIEGASEGAGLGIRFLKHVARTRR
LLHLVDIKPIDGSDPVENARVILNELERFSPELANLPQILVLNKIDQVPEEELNELCTHIVAELGWTGIVFRTATLTGEG
VDAIKYHLMNEIEREREREIEDPIFADAQKARFERLEAEVRLNTEAQREAYRAARKAAREGTDLSDDDFDDSDDDDDGVE
VVYAP
>Mature_405_residues
MRFIDEAVVTVKAGDGGNGIASFRREKYVPRGGPDGGDGGKGGDVYVIAEDNTNTLVDYRYTRRHDAMRAENGHSRNCSG
KGSDDLFLPVPIGTTVVDTETDEVLGDLIEIGQTLLIAKGGDGGLGNTHFKSSTNQAPRKATSGFEGELKVLKFELKVVA
DVGLIGLPNAGKSTFIRQVSAARPKVADYPFTTLVPNLGVVDIGRHRSFVMADIPGLIEGASEGAGLGIRFLKHVARTRR
LLHLVDIKPIDGSDPVENARVILNELERFSPELANLPQILVLNKIDQVPEEELNELCTHIVAELGWTGIVFRTATLTGEG
VDAIKYHLMNEIEREREREIEDPIFADAQKARFERLEAEVRLNTEAQREAYRAARKAAREGTDLSDDDFDDSDDDDDGVE
VVYAP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=326, Percent_Identity=40.1840490797546, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI111955139, Length=340, Percent_Identity=33.8235294117647, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI111955063, Length=207, Percent_Identity=34.2995169082126, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4758796, Length=155, Percent_Identity=34.8387096774194, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=32.5581395348837, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789574, Length=357, Percent_Identity=55.4621848739496, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=33.59375, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=302, Percent_Identity=41.0596026490066, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=30.5194805194805, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=36.71875, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=155, Percent_Identity=32.258064516129, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=164, Percent_Identity=38.4146341463415, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=35.15625, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24585318, Length=311, Percent_Identity=33.7620578778135, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI20129375, Length=220, Percent_Identity=40.4545454545455, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=33.59375, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=33.59375, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=33.59375, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17981711, Length=153, Percent_Identity=32.6797385620915, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 44222; Mature: 44222

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIDEAVVTVKAGDGGNGIASFRREKYVPRGGPDGGDGGKGGDVYVIAEDNTNTLVDYR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEE
YTRRHDAMRAENGHSRNCSGKGSDDLFLPVPIGTTVVDTETDEVLGDLIEIGQTLLIAKG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHCCCEEEEEEC
GDGGLGNTHFKSSTNQAPRKATSGFEGELKVLKFELKVVADVGLIGLPNAGKSTFIRQVS
CCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEHCCCCEEECCCCCHHHHHHHHH
AARPKVADYPFTTLVPNLGVVDIGRHRSFVMADIPGLIEGASEGAGLGIRFLKHVARTRR
HCCCCCCCCCHHHHCCCCCEEEECCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHLVDIKPIDGSDPVENARVILNELERFSPELANLPQILVLNKIDQVPEEELNELCTHI
HHHHEEEECCCCCCCHHHHHHHHHHHHHHCHHHHCCCCEEEHHHHHCCCHHHHHHHHHHH
VAELGWTGIVFRTATLTGEGVDAIKYHLMNEIEREREREIEDPIFADAQKARFERLEAEV
HHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHE
RLNTEAQREAYRAARKAAREGTDLSDDDFDDSDDDDDGVEVVYAP
EECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MRFIDEAVVTVKAGDGGNGIASFRREKYVPRGGPDGGDGGKGGDVYVIAEDNTNTLVDYR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEE
YTRRHDAMRAENGHSRNCSGKGSDDLFLPVPIGTTVVDTETDEVLGDLIEIGQTLLIAKG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHCCCEEEEEEC
GDGGLGNTHFKSSTNQAPRKATSGFEGELKVLKFELKVVADVGLIGLPNAGKSTFIRQVS
CCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEHCCCCEEECCCCCHHHHHHHHH
AARPKVADYPFTTLVPNLGVVDIGRHRSFVMADIPGLIEGASEGAGLGIRFLKHVARTRR
HCCCCCCCCCHHHHCCCCCEEEECCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHLVDIKPIDGSDPVENARVILNELERFSPELANLPQILVLNKIDQVPEEELNELCTHI
HHHHEEEECCCCCCCHHHHHHHHHHHHHHCHHHHCCCCEEEHHHHHCCCHHHHHHHHHHH
VAELGWTGIVFRTATLTGEGVDAIKYHLMNEIEREREREIEDPIFADAQKARFERLEAEV
HHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHE
RLNTEAQREAYRAARKAAREGTDLSDDDFDDSDDDDDGVEVVYAP
EECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA