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The map label for this gene is ppiD [H]

Identifier: 93006476

GI number: 93006476

Start: 2035541

End: 2037415

Strand: Reverse

Name: ppiD [H]

Synonym: Pcryo_1652

Alternate gene names: 93006476

Gene position: 2037415-2035541 (Counterclockwise)

Preceding gene: 93006477

Following gene: 93006469

Centisome position: 66.58

GC content: 44.0

Gene sequence:

>1875_bases
ATGGATAAATTGCGCGATTTCTTAAAAAGCTGGCCGGGTCGCATTTTATTGATTTTATGCCTATCGCCGCTCGCTCTATT
GGGCGTCGAAAGTTACTTTGGGGGTAATGTCGATCCCAATCAGATCGCTCAGGTAGGGGAAGCGAGTATCGGCCTATCAG
AGTATCAAACGGCAGTAAACAATCGCCGTACTGAGCTTTTAGACCAAGTTGATGATGCCAGTTTATTAAATGAAGATGTG
CTACATGAGCAAGTGTTAAAAGGTCTGATTGACCGCACCTTGCTAGAGCAGCAGGCTGGCAAGCTTGGTATGACCGTCTC
TGATGACACCATCAATCGTCTGTTGCGTCAAGAAGAGATCTTTAAAGGTGCAGATGGCGAGTTTTCAAATGATCAGTTTG
CAAGCTTTTTACGTCAACGCAATATGACAAAAAATCAGCTGTTTGATGAGTTCCGCAATCAGTTGAGCTTAGATCAGCTG
AATGCTAGTATCGTTGGTACTGCTGCCTATCCGATGAAAGCAGTCAGTCAACTGATTAATTTGCAGCTAGAGGCACGCAA
TATTTGGCTACATCGTTTTAACTGGCAAGATTATGTGTCAAAAGTTAAATTGAGTAAAAATGACATTCAAGCATATTATG
ATGCCAATAAAGACACGCTAAAGAGCGCTGCTATGGTCGATTTGGCTTACTTGCAGCTTAGCCCTCAGACCATCCAAGTA
AACGAGGTCACTAAAGAGGACTTACAGCAGCAGTACGAAGCCTATAAGCAAAGCCTTGCCGTCGTCGATGAGCGTAAGAT
CAGCCAAATCTTATTAACTGGTAGCGATGCCAAAGCACGTGCTGATAAAATTAAAGCGCGTCTTGCCAAAGGTGAAGCCT
TTGCGAAGGTTGCTAAAGCTGAGTCAGATGATCCATCCGGCGAAACAGGCGGCGATATCGGACGCTTTAATCCCTCAGTA
TTTGGCAATGACGCTGCAGCAGTAGAAAAAGCGTTAGAAGGTTTGAGTGTAGGCGATATCAGCGTACCGGTGAAGACCAG
CTTTGGTTATCAGATATTTACGGTGACTGAAGATAATGGTAACAAGATACCAAGCCTTGAGAGTATGCGTGATGATTTGA
TAGCCAAAGCAAAAGAGTACAAGCGTCAAGAAATCTACGCTGACAAAGTAACGGCGATTAACGATTTAGCCGCAGATGGG
TTTAGTATTGAAGATATTGCTCAGCAAGAAAATGTGTCATTAAAACGTCTTAAAGATTATCGCAAAGAGAACAATAAATC
TGTCCTTGCCCAGCCAGCGGTGATTAAACAAGCGTTTGATGAGTTTACCATTCAAGACCAAGCGGTCACCGCTGGTATCG
AAGTTGGTAATGGCACAGTATGGGTACAGCCAAGTAACTATCGTCCTACCAAAACATTGTCCTTAACTGCTGCGACGCCT
AGAATCACGCAGTTATTACGTCAGCAAAAGGCTAGTGAATTGGCATTAAATGATGCGAAAAAACTTGCGGCTGGTATTAA
GACTACCGCTGATATCAATAAGCAAGGGGTAACATTCCAAGCGCTTGGTGAGATCAATCGTCAGACTACGCAGCTGACAG
AAAAAGAGCGCGGCTTAGCGTTTAGTAAGCAAGCACCTGAGAACGGTGTGGTTGCCGTAGCAAGTAAAACAGAAATGGGC
GCAACGGTATTGGTTGGTGACCGTATCAAAACAGAGCAGCAATCACCATTATCTGCCGCCCAAAGAGCGCAAACGGCAGC
GATTATCCGTGATAATTTAGGCCAAGATCAGCTACAAGATTACTTAGACTATTTGCGTTTGGTGTATAAGGTTGAGATTA
ATAAAGCCAATATGGAAAATGCTCAAGGGCGATAA

Upstream 100 bases:

>100_bases
TTTACCATTTTCTTACCATTGCCAGCTTGTAGAGCGTTGATATTATTAATAGTATTACAATGGTTTTTCATCAATATAGG
TTAATAAAGCAGAGATAACT

Downstream 100 bases:

>100_bases
GTACTTTGTGCGCTATCCATTTTAAATAAAGCTATTTTTAACCATTAAAAAAGCCACTGTAATCATACAGTGGCTTTTTT
TATTCAAGGGTAAGCATTTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MDKLRDFLKSWPGRILLILCLSPLALLGVESYFGGNVDPNQIAQVGEASIGLSEYQTAVNNRRTELLDQVDDASLLNEDV
LHEQVLKGLIDRTLLEQQAGKLGMTVSDDTINRLLRQEEIFKGADGEFSNDQFASFLRQRNMTKNQLFDEFRNQLSLDQL
NASIVGTAAYPMKAVSQLINLQLEARNIWLHRFNWQDYVSKVKLSKNDIQAYYDANKDTLKSAAMVDLAYLQLSPQTIQV
NEVTKEDLQQQYEAYKQSLAVVDERKISQILLTGSDAKARADKIKARLAKGEAFAKVAKAESDDPSGETGGDIGRFNPSV
FGNDAAAVEKALEGLSVGDISVPVKTSFGYQIFTVTEDNGNKIPSLESMRDDLIAKAKEYKRQEIYADKVTAINDLAADG
FSIEDIAQQENVSLKRLKDYRKENNKSVLAQPAVIKQAFDEFTIQDQAVTAGIEVGNGTVWVQPSNYRPTKTLSLTAATP
RITQLLRQQKASELALNDAKKLAAGIKTTADINKQGVTFQALGEINRQTTQLTEKERGLAFSKQAPENGVVAVASKTEMG
ATVLVGDRIKTEQQSPLSAAQRAQTAAIIRDNLGQDQLQDYLDYLRLVYKVEINKANMENAQGR

Sequences:

>Translated_624_residues
MDKLRDFLKSWPGRILLILCLSPLALLGVESYFGGNVDPNQIAQVGEASIGLSEYQTAVNNRRTELLDQVDDASLLNEDV
LHEQVLKGLIDRTLLEQQAGKLGMTVSDDTINRLLRQEEIFKGADGEFSNDQFASFLRQRNMTKNQLFDEFRNQLSLDQL
NASIVGTAAYPMKAVSQLINLQLEARNIWLHRFNWQDYVSKVKLSKNDIQAYYDANKDTLKSAAMVDLAYLQLSPQTIQV
NEVTKEDLQQQYEAYKQSLAVVDERKISQILLTGSDAKARADKIKARLAKGEAFAKVAKAESDDPSGETGGDIGRFNPSV
FGNDAAAVEKALEGLSVGDISVPVKTSFGYQIFTVTEDNGNKIPSLESMRDDLIAKAKEYKRQEIYADKVTAINDLAADG
FSIEDIAQQENVSLKRLKDYRKENNKSVLAQPAVIKQAFDEFTIQDQAVTAGIEVGNGTVWVQPSNYRPTKTLSLTAATP
RITQLLRQQKASELALNDAKKLAAGIKTTADINKQGVTFQALGEINRQTTQLTEKERGLAFSKQAPENGVVAVASKTEMG
ATVLVGDRIKTEQQSPLSAAQRAQTAAIIRDNLGQDQLQDYLDYLRLVYKVEINKANMENAQGR
>Mature_624_residues
MDKLRDFLKSWPGRILLILCLSPLALLGVESYFGGNVDPNQIAQVGEASIGLSEYQTAVNNRRTELLDQVDDASLLNEDV
LHEQVLKGLIDRTLLEQQAGKLGMTVSDDTINRLLRQEEIFKGADGEFSNDQFASFLRQRNMTKNQLFDEFRNQLSLDQL
NASIVGTAAYPMKAVSQLINLQLEARNIWLHRFNWQDYVSKVKLSKNDIQAYYDANKDTLKSAAMVDLAYLQLSPQTIQV
NEVTKEDLQQQYEAYKQSLAVVDERKISQILLTGSDAKARADKIKARLAKGEAFAKVAKAESDDPSGETGGDIGRFNPSV
FGNDAAAVEKALEGLSVGDISVPVKTSFGYQIFTVTEDNGNKIPSLESMRDDLIAKAKEYKRQEIYADKVTAINDLAADG
FSIEDIAQQENVSLKRLKDYRKENNKSVLAQPAVIKQAFDEFTIQDQAVTAGIEVGNGTVWVQPSNYRPTKTLSLTAATP
RITQLLRQQKASELALNDAKKLAAGIKTTADINKQGVTFQALGEINRQTTQLTEKERGLAFSKQAPENGVVAVASKTEMG
ATVLVGDRIKTEQQSPLSAAQRAQTAAIIRDNLGQDQLQDYLDYLRLVYKVEINKANMENAQGR

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=526, Percent_Identity=26.2357414448669, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69085; Mature: 69085

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLRDFLKSWPGRILLILCLSPLALLGVESYFGGNVDPNQIAQVGEASIGLSEYQTAVN
CHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHH
NRRTELLDQVDDASLLNEDVLHEQVLKGLIDRTLLEQQAGKLGMTVSDDTINRLLRQEEI
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHH
FKGADGEFSNDQFASFLRQRNMTKNQLFDEFRNQLSLDQLNASIVGTAAYPMKAVSQLIN
HCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHCCCEEECCHHHHHHHHHHHC
LQLEARNIWLHRFNWQDYVSKVKLSKNDIQAYYDANKDTLKSAAMVDLAYLQLSPQTIQV
CEEEEEEEEEEECCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCEEEE
NEVTKEDLQQQYEAYKQSLAVVDERKISQILLTGSDAKARADKIKARLAKGEAFAKVAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHHHHC
ESDDPSGETGGDIGRFNPSVFGNDAAAVEKALEGLSVGDISVPVKTSFGYQIFTVTEDNG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEECCCC
NKIPSLESMRDDLIAKAKEYKRQEIYADKVTAINDLAADGFSIEDIAQQENVSLKRLKDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
RKENNKSVLAQPAVIKQAFDEFTIQDQAVTAGIEVGNGTVWVQPSNYRPTKTLSLTAATP
HHCCCCEEECCHHHHHHHHHHHCCCCHHEEEEEEECCCEEEEECCCCCCCCEEEEECCCH
RITQLLRQQKASELALNDAKKLAAGIKTTADINKQGVTFQALGEINRQTTQLTEKERGLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCE
FSKQAPENGVVAVASKTEMGATVLVGDRIKTEQQSPLSAAQRAQTAAIIRDNLGQDQLQD
ECCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
YLDYLRLVYKVEINKANMENAQGR
HHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure
MDKLRDFLKSWPGRILLILCLSPLALLGVESYFGGNVDPNQIAQVGEASIGLSEYQTAVN
CHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHH
NRRTELLDQVDDASLLNEDVLHEQVLKGLIDRTLLEQQAGKLGMTVSDDTINRLLRQEEI
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHH
FKGADGEFSNDQFASFLRQRNMTKNQLFDEFRNQLSLDQLNASIVGTAAYPMKAVSQLIN
HCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHCCCEEECCHHHHHHHHHHHC
LQLEARNIWLHRFNWQDYVSKVKLSKNDIQAYYDANKDTLKSAAMVDLAYLQLSPQTIQV
CEEEEEEEEEEECCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCEEEE
NEVTKEDLQQQYEAYKQSLAVVDERKISQILLTGSDAKARADKIKARLAKGEAFAKVAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHHHHC
ESDDPSGETGGDIGRFNPSVFGNDAAAVEKALEGLSVGDISVPVKTSFGYQIFTVTEDNG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEECCCC
NKIPSLESMRDDLIAKAKEYKRQEIYADKVTAINDLAADGFSIEDIAQQENVSLKRLKDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
RKENNKSVLAQPAVIKQAFDEFTIQDQAVTAGIEVGNGTVWVQPSNYRPTKTLSLTAATP
HHCCCCEEECCHHHHHHHHHHHCCCCHHEEEEEEECCCEEEEECCCCCCCCEEEEECCCH
RITQLLRQQKASELALNDAKKLAAGIKTTADINKQGVTFQALGEINRQTTQLTEKERGLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCE
FSKQAPENGVVAVASKTEMGATVLVGDRIKTEQQSPLSAAQRAQTAAIIRDNLGQDQLQD
ECCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
YLDYLRLVYKVEINKANMENAQGR
HHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]