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The map label for this gene is mmgC [H]

Identifier: 93006342

GI number: 93006342

Start: 1863130

End: 1864290

Strand: Reverse

Name: mmgC [H]

Synonym: Pcryo_1516

Alternate gene names: 93006342

Gene position: 1864290-1863130 (Counterclockwise)

Preceding gene: 93006343

Following gene: 93006341

Centisome position: 60.93

GC content: 47.29

Gene sequence:

>1161_bases
ATGGATTTTTCATTAACCGATGACCAAATTGCCTTTCGCCAAACTGCTAGACAGTTTGCCCAAAAAGAGCTTAAGCCCAA
CGCTGCTGAATGGGATCGCACTTCGCACTTCCCAATTGATGTGATTAAAAAATCAGGCGAGCTTGGCTTTTTAGGGTTAT
ATACCAACCCTGAGTATGATGGCTTGGGCTTGCCGCGTTTAGATTCTGCCATGGTTTTTGAAGAGCTAGCATGGGGTGAT
ACCGCGGTGGCTGCTTATATGAGTATTCATAATATGGCAGGCTGGATGATTGGTGAGTTTGGCAGTGATACATTGTGCAA
AAAATATTTGCCAAATATGGTCAGTGGTGAATGGCTTGGCAGCTACTGCTTAACAGAACCTAATGCCGGTTCTGATGCCG
CATCATTACGTACCAAAGCCGATAAGCAAGGCGAGTATTATGTGCTGAACGGTGAAAAAACCTTTATTTCAGGGGCCGGC
TCAACCGATGTGTTGGTCGTTATGGCGCGTACGGGCGCTGCAGGACCAAAGGGGATTTCAGCATTCGTGGTTGATGCCGA
TAGTGCTGGTATTGAATACGGCAAAAACGAGCATAAAATGGGCTGGAAAGCACAGCCAACACGGACGATAAGCTTTAAAG
ATGTCAAAGTGCCAGTAGAGAACCTCATCGGCGAAGAAGGTCAAGGCTTTCGTATCGCTATGAAAGGGTTAGATGGCGGT
CGAATTAATATTGGTATCTGTGCAGTAGGAACAGCGCAAGCAGCGCTTGAGACAGCGACCAATTACGTGCAAGAGCGCAG
TCAGTTTGGCAGCCCGATTGCCAGCTTACAGTCGGTACAGTTTAAGCTTGCTGATATGTTGACTCAAACCATCACGGCAC
GGCAAATGCTGTATTTAGCGGCGAGCAAAGTCGACAATAACGATGCGCAAGCCTCTACTTATTGTGCGATGGCAAAGCGT
TTATCGACCGATCTTTGTTTTGATGTCGCTAACGAAGCTCTGCAACTACACGGTGGTTACGGCTATCTCAATGAGTATCC
GCTTGAGCGTCATGTGCGAGATTTGCGTGTGCATCAGATTTTGGAAGGCACCAATGAGATTATGCGCGTGATTGTCTCGC
GTCAGCTATTACAAGACGATGCATTGAGCCAACTGCGCTAA

Upstream 100 bases:

>100_bases
GGCAAGTCGCGGTGTCAATACGACTATTTCAATTTAACGCTGAATCACCTATATTTGCACTGACGACTTAATATACCCTA
TTCAGCACAAGGATGACCCC

Downstream 100 bases:

>100_bases
CCTATTTATATGAATAAAATGATTTTATGATAAGGATGTTTGATCATGACGGATTATACCAACTTAAAACTATCGATTGA
TGGTCATACTGCGACATTAA

Product: butyryl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDFSLTDDQIAFRQTARQFAQKELKPNAAEWDRTSHFPIDVIKKSGELGFLGLYTNPEYDGLGLPRLDSAMVFEELAWGD
TAVAAYMSIHNMAGWMIGEFGSDTLCKKYLPNMVSGEWLGSYCLTEPNAGSDAASLRTKADKQGEYYVLNGEKTFISGAG
STDVLVVMARTGAAGPKGISAFVVDADSAGIEYGKNEHKMGWKAQPTRTISFKDVKVPVENLIGEEGQGFRIAMKGLDGG
RINIGICAVGTAQAALETATNYVQERSQFGSPIASLQSVQFKLADMLTQTITARQMLYLAASKVDNNDAQASTYCAMAKR
LSTDLCFDVANEALQLHGGYGYLNEYPLERHVRDLRVHQILEGTNEIMRVIVSRQLLQDDALSQLR

Sequences:

>Translated_386_residues
MDFSLTDDQIAFRQTARQFAQKELKPNAAEWDRTSHFPIDVIKKSGELGFLGLYTNPEYDGLGLPRLDSAMVFEELAWGD
TAVAAYMSIHNMAGWMIGEFGSDTLCKKYLPNMVSGEWLGSYCLTEPNAGSDAASLRTKADKQGEYYVLNGEKTFISGAG
STDVLVVMARTGAAGPKGISAFVVDADSAGIEYGKNEHKMGWKAQPTRTISFKDVKVPVENLIGEEGQGFRIAMKGLDGG
RINIGICAVGTAQAALETATNYVQERSQFGSPIASLQSVQFKLADMLTQTITARQMLYLAASKVDNNDAQASTYCAMAKR
LSTDLCFDVANEALQLHGGYGYLNEYPLERHVRDLRVHQILEGTNEIMRVIVSRQLLQDDALSQLR
>Mature_386_residues
MDFSLTDDQIAFRQTARQFAQKELKPNAAEWDRTSHFPIDVIKKSGELGFLGLYTNPEYDGLGLPRLDSAMVFEELAWGD
TAVAAYMSIHNMAGWMIGEFGSDTLCKKYLPNMVSGEWLGSYCLTEPNAGSDAASLRTKADKQGEYYVLNGEKTFISGAG
STDVLVVMARTGAAGPKGISAFVVDADSAGIEYGKNEHKMGWKAQPTRTISFKDVKVPVENLIGEEGQGFRIAMKGLDGG
RINIGICAVGTAQAALETATNYVQERSQFGSPIASLQSVQFKLADMLTQTITARQMLYLAASKVDNNDAQASTYCAMAKR
LSTDLCFDVANEALQLHGGYGYLNEYPLERHVRDLRVHQILEGTNEIMRVIVSRQLLQDDALSQLR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=51.7333333333333, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=38.2585751978892, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=38.2585751978892, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI4557233, Length=368, Percent_Identity=39.945652173913, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI4501857, Length=372, Percent_Identity=36.0215053763441, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=34.1333333333333, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=35.4330708661417, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI4557235, Length=342, Percent_Identity=36.8421052631579, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI76496475, Length=342, Percent_Identity=36.8421052631579, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=35.4838709677419, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI21361497, Length=361, Percent_Identity=34.0720221606648, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=32.1052631578947, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI7669494, Length=359, Percent_Identity=32.3119777158774, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI48976061, Length=374, Percent_Identity=26.2032085561497, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI211971008, Length=374, Percent_Identity=26.2032085561497, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI38505218, Length=337, Percent_Identity=27.0029673590504, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=31.6753926701571, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=28.7206266318538, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI87082384, Length=259, Percent_Identity=26.6409266409266, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081702, Length=260, Percent_Identity=25.3846153846154, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=49.5956873315364, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534899, Length=385, Percent_Identity=38.4415584415584, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=38.0577427821522, Blast_Score=277, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=35.9580052493438, Blast_Score=264, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=35.3403141361257, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=34.5714285714286, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=32.8767123287671, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=32.8767123287671, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=32.010582010582, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=310, Percent_Identity=33.5483870967742, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=272, Percent_Identity=35.6617647058824, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI71982178, Length=269, Percent_Identity=33.457249070632, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=28.6096256684492, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17505929, Length=365, Percent_Identity=28.7671232876712, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=35.0649350649351, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=26.969696969697, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=233, Percent_Identity=26.6094420600858, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=335, Percent_Identity=25.3731343283582, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=335, Percent_Identity=25.3731343283582, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=37.3684210526316, Blast_Score=268, Evalue=5e-72,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=37.7952755905512, Blast_Score=250, Evalue=9e-67,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=36.0313315926893, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=36.604774535809, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=34.5646437994723, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=35.3623188405797, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=32.0209973753281, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24652780, Length=318, Percent_Identity=23.8993710691824, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42289; Mature: 42289

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLTDDQIAFRQTARQFAQKELKPNAAEWDRTSHFPIDVIKKSGELGFLGLYTNPEYD
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCC
GLGLPRLDSAMVFEELAWGDTAVAAYMSIHNMAGWMIGEFGSDTLCKKYLPNMVSGEWLG
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHC
SYCLTEPNAGSDAASLRTKADKQGEYYVLNGEKTFISGAGSTDVLVVMARTGAAGPKGIS
HHHCCCCCCCCCHHHHHHCCCCCCCEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCE
AFVVDADSAGIEYGKNEHKMGWKAQPTRTISFKDVKVPVENLIGEEGQGFRIAMKGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCCCCCCEEEEEECCCCC
RINIGICAVGTAQAALETATNYVQERSQFGSPIASLQSVQFKLADMLTQTITARQMLYLA
EEEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKVDNNDAQASTYCAMAKRLSTDLCFDVANEALQLHGGYGYLNEYPLERHVRDLRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHH
LEGTNEIMRVIVSRQLLQDDALSQLR
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFSLTDDQIAFRQTARQFAQKELKPNAAEWDRTSHFPIDVIKKSGELGFLGLYTNPEYD
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCC
GLGLPRLDSAMVFEELAWGDTAVAAYMSIHNMAGWMIGEFGSDTLCKKYLPNMVSGEWLG
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHC
SYCLTEPNAGSDAASLRTKADKQGEYYVLNGEKTFISGAGSTDVLVVMARTGAAGPKGIS
HHHCCCCCCCCCHHHHHHCCCCCCCEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCE
AFVVDADSAGIEYGKNEHKMGWKAQPTRTISFKDVKVPVENLIGEEGQGFRIAMKGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCCCCCCEEEEEECCCCC
RINIGICAVGTAQAALETATNYVQERSQFGSPIASLQSVQFKLADMLTQTITARQMLYLA
EEEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKVDNNDAQASTYCAMAKRLSTDLCFDVANEALQLHGGYGYLNEYPLERHVRDLRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHH
LEGTNEIMRVIVSRQLLQDDALSQLR
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]