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The map label for this gene is apaH [H]

Identifier: 93006281

GI number: 93006281

Start: 1794967

End: 1795809

Strand: Reverse

Name: apaH [H]

Synonym: Pcryo_1455

Alternate gene names: 93006281

Gene position: 1795809-1794967 (Counterclockwise)

Preceding gene: 93006282

Following gene: 93006272

Centisome position: 58.69

GC content: 45.08

Gene sequence:

>843_bases
ATGAGTTATCGTCATCAGTATGTTATCGGTGATTTGCAAGGCTGCTATGCTGCGTATCTTCAGCTACTTAAAACATTGGA
TTTTGATCCAGAACAAGATAAATTATGGTTTGCAGGCGACTTAGTGGCACGTGGCGAGGACTCTTTAAATACCTTGCGTC
ATGTCAAAGATTTGTGTGAGCAAGGGGCAGCCGCGACTGTACTTGGCAATCATGATATCAATTTGCTAGCCGTATGGCGT
GGGGCGACGAAAATTAAGAAAAAAGATAAGACAGCACCGATTTTTGCAGCTGATGATTGTGATGAGTTGCTAGAGTGGCT
ACGTCATCAGCCATTATTGGTTTATCCTGATAAGCATACGGTGCTGGTGCATGCTGGTATTCCGCCGCATTGGAGTATTG
AAGACGCCGAAAAGTATGCACATCAGTTAGAGTCGCAGTTGCGAAGTCATTTAAAACAGCTTGATAGATTGTTGCCAAAT
CTCTATAGCAAGACGGCAGATAATTGGCATGCAGACATTCATGGATTTACGAAAATGCGAGCGATTGCCAATTATTTTAC
TCGCATGCGCTTATGTCAGCAGGATGGGCTGCTTGAATTTAGCTTTACATCAGGGCTAGATGAGCGCATGCCAGAGGATT
TTTTACCTTGGTTTGAATGGCAAGTGCCGCGCACTCGTAAGGTGTTATTTGGGCATTGGGCCGCGCTCAAAGGTGAAGTT
GATCTGCCTTATGCTCGTGCACTAGATGGTGGCTGTGTTTGGGGTAATCATTTGCTAGCCTATCGCTTAAGTGATGGCAA
GACCATCACGTCAAGTGCGCAGTGCTTGCCGATATCTTCTTAA

Upstream 100 bases:

>100_bases
CGCGTAAAGTAGAAGGCTGATTTATCAGTGCTATTCATACCGTAGATATCATTCATTGCTAAGTAGTATCTACAATATTC
ACAAGAAAGATTGAGAGCTT

Downstream 100 bases:

>100_bases
TTTTTTAGTGATTCCAAAAACCAATCAAGCCATCAAATTAACCCATTAACTGGGTAGATTTGGTGGCTTTTTTGGTTTAG
GTAGTGGCGTTTTGGCGTCG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSYRHQYVIGDLQGCYAAYLQLLKTLDFDPEQDKLWFAGDLVARGEDSLNTLRHVKDLCEQGAAATVLGNHDINLLAVWR
GATKIKKKDKTAPIFAADDCDELLEWLRHQPLLVYPDKHTVLVHAGIPPHWSIEDAEKYAHQLESQLRSHLKQLDRLLPN
LYSKTADNWHADIHGFTKMRAIANYFTRMRLCQQDGLLEFSFTSGLDERMPEDFLPWFEWQVPRTRKVLFGHWAALKGEV
DLPYARALDGGCVWGNHLLAYRLSDGKTITSSAQCLPISS

Sequences:

>Translated_280_residues
MSYRHQYVIGDLQGCYAAYLQLLKTLDFDPEQDKLWFAGDLVARGEDSLNTLRHVKDLCEQGAAATVLGNHDINLLAVWR
GATKIKKKDKTAPIFAADDCDELLEWLRHQPLLVYPDKHTVLVHAGIPPHWSIEDAEKYAHQLESQLRSHLKQLDRLLPN
LYSKTADNWHADIHGFTKMRAIANYFTRMRLCQQDGLLEFSFTSGLDERMPEDFLPWFEWQVPRTRKVLFGHWAALKGEV
DLPYARALDGGCVWGNHLLAYRLSDGKTITSSAQCLPISS
>Mature_279_residues
SYRHQYVIGDLQGCYAAYLQLLKTLDFDPEQDKLWFAGDLVARGEDSLNTLRHVKDLCEQGAAATVLGNHDINLLAVWRG
ATKIKKKDKTAPIFAADDCDELLEWLRHQPLLVYPDKHTVLVHAGIPPHWSIEDAEKYAHQLESQLRSHLKQLDRLLPNL
YSKTADNWHADIHGFTKMRAIANYFTRMRLCQQDGLLEFSFTSGLDERMPEDFLPWFEWQVPRTRKVLFGHWAALKGEVD
LPYARALDGGCVWGNHLLAYRLSDGKTITSSAQCLPISS

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=262, Percent_Identity=41.2213740458015, Blast_Score=197, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 32001; Mature: 31870

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRHQYVIGDLQGCYAAYLQLLKTLDFDPEQDKLWFAGDLVARGEDSLNTLRHVKDLCE
CCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHH
QGAAATVLGNHDINLLAVWRGATKIKKKDKTAPIFAADDCDELLEWLRHQPLLVYPDKHT
CCCEEEEECCCCCEEEEEECCCHHHHHCCCCCCEEECCCHHHHHHHHHCCCEEEECCCCE
VLVHAGIPPHWSIEDAEKYAHQLESQLRSHLKQLDRLLPNLYSKTADNWHADIHGFTKMR
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AIANYFTRMRLCQQDGLLEFSFTSGLDERMPEDFLPWFEWQVPRTRKVLFGHWAALKGEV
HHHHHHHHHHHHHHCCCEEEECCCCCHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
DLPYARALDGGCVWGNHLLAYRLSDGKTITSSAQCLPISS
CCCHHHHCCCCEEECCCEEEEEECCCCEECCCCCEEECCC
>Mature Secondary Structure 
SYRHQYVIGDLQGCYAAYLQLLKTLDFDPEQDKLWFAGDLVARGEDSLNTLRHVKDLCE
CCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHH
QGAAATVLGNHDINLLAVWRGATKIKKKDKTAPIFAADDCDELLEWLRHQPLLVYPDKHT
CCCEEEEECCCCCEEEEEECCCHHHHHCCCCCCEEECCCHHHHHHHHHCCCEEEECCCCE
VLVHAGIPPHWSIEDAEKYAHQLESQLRSHLKQLDRLLPNLYSKTADNWHADIHGFTKMR
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AIANYFTRMRLCQQDGLLEFSFTSGLDERMPEDFLPWFEWQVPRTRKVLFGHWAALKGEV
HHHHHHHHHHHHHHCCCEEEECCCCCHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
DLPYARALDGGCVWGNHLLAYRLSDGKTITSSAQCLPISS
CCCHHHHCCCCEEECCCEEEEEECCCCEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA