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The map label for this gene is yhdY [H]

Identifier: 93006272

GI number: 93006272

Start: 1778049

End: 1779995

Strand: Reverse

Name: yhdY [H]

Synonym: Pcryo_1446

Alternate gene names: 93006272

Gene position: 1779995-1778049 (Counterclockwise)

Preceding gene: 93006281

Following gene: 93006266

Centisome position: 58.17

GC content: 41.86

Gene sequence:

>1947_bases
ATGAGGTTTGTTTTGTTTATTAAACATCGTCTGAATACCACTACCGTGCCATCTTTATCGATGTCATTGATGAAATTACC
ATTAATCGTGATAACACTACTCGTTGCTATGGCACTTAGTATCCTCTCGCAGCCTAGTGCGTTGGCAGCTGAGACGAGCA
TACTGGGTGTGGGTGGGACTAAGACTGAGGAAGGGGATGGCACATCGATACCTGATTCATTCGGACGCGATACGCCTCGG
CATACGGTGCAAGGATTTATTGCAGCATTGGGTGAAAATGATTATTTGCTGGCGAGTAATTACTTAAATCTATCTAAATC
TGATAATCCCACAACCATTGTACGACAGTTCAAGCAAGCCCTCGATGCAGGTGGTCGTTTTCAGGCTGATCTACAGATTA
ATAATACGCCTGAAGGCAATTTGACCGATCAGCTACCGCCAAGCCAAGAAAATGTAGGTGTCATCAAAGTCAGTGATGCC
AGCATTCCTCTATTACTTGAAAGAGTGGTGTCAAAAGAAGGTGAGCAATATTGGCAGTTTTCTACCGATACACTCAGCTC
AATACCAGAGGCGATAGAGAACTATGAGCCGACTTTGGTTTCTCGTTATACCATTGACTCGTTGGAAGGCAAAAAGCTTT
TTGGTTATCAGTTGGCTGATTTGGTAGCCGCTTTAATGATTACTATCAGTAGTTTTTTGTTCACGTACATCGCAGTATGG
CTATTGTATCATTTATTAGAAATCACTTACCCTCGTGTCCGTGATGTACCGCTACCATTGCCAGATAAAGTGATATTGCC
GCTAGCGGTGGTGATTATGGCGCTGATTTTATCTGAGGTGATGGTTTATGCGGGCGTGTCAGTGACCCTGCGCGAGCCTG
TCAACCGTTTCGCCGAGATTGCTTCGTGGGTGGCGATAACGTGGTTGTTATTACGCATTATCGATGCATTATTTACCCGT
GCAGTGAACTTAAGCTATAAGAAAAACTATACTGAACGGGTCTCAATTTTGGGGCTACTACGCAAAGTCGTCAAAGCACT
GCTATTGATATTTGCAGTCATTGTCACTTTTGGTAACTTGGGCTTTGACTTAACGACGGGTATTGCGGCACTAGGTGTCG
GTGGTTTAGCGTTAGCATTAGGTGCGCAAAAGACCATCGAAAACTTAGTCGGTAGTGTGGTAGTAGTGGCAGATTCGCCC
GTACGTATCGGTGATTATTGCAAGTTTGGTACCTATGAAGGTACTGTTATTGATATTGGTATTCGCTCATCGCGCGTGCG
TACTTTGACTCGCACTATCGTCACAGTACCTAATGGTGATTTTTCATCGATGCAAATTGAAAACTTTACCTCGCGTGATA
TGTTCCGCTTTTTGCATCAGCTATATATCAAGCGTACCGCTGATATCGATGTTGTGTTTAAAATGGTCAAGCACTTGGAT
ACGTTTTTGGATGAGCATGAATTAACCAATCAAGAATGGAACCAAGTCAATATCTTAGAGTTGCGTCAAGATTGTTATAT
TATTCAATTGCAAGCCTATATCAATGCCACTGGTATCATCGAATTCTATGAAAAACAAGATGTGTTATTTGTTGATCTAT
TAATGCAAGTTAGAAAGTATGATGTAGAGCATGCCCTGCCAACACAGCAGCTGATTGTTAAGCAACCAGAGCTTCAGGCT
GAATTAGATCATGAAAGTAAAGAAGGCGAGACGGTTGACAAGAAAGCTGATAAAAAAAATGCTGCTGCTGATAAGCCTGA
AGCCGTTAATTTAAGCAAAGATGTGGATACTATTGATGATGAGCAGACCGCAGATAAACCCAAAGATGGCTTAAAAAAGG
ATATGATCGACAATAGATACAAACGCATTCATAAAAATCGTGGGTATAATTTAGCAAAACTAAAGTTCAAGCAGGTTAAA
AAGAGCTTTAGATTCCCTAAGATATGA

Upstream 100 bases:

>100_bases
CTATTTATCATTTTTTTATTCACTAGTGATATTTTTGACCATCATAATTGTTATTATAGGGCAGATTTTTCCCGTTTTTC
GTTATGCCATTCATAAAGCC

Downstream 100 bases:

>100_bases
AGCATTTAATAAGATAGCCTATTATAAAGGCACTGCTTTTCTATTATTTAGCCAGCCGTAATGTGACCATAGTAGTAAGC
TAGCAGCACTCCGATGTGGC

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MRFVLFIKHRLNTTTVPSLSMSLMKLPLIVITLLVAMALSILSQPSALAAETSILGVGGTKTEEGDGTSIPDSFGRDTPR
HTVQGFIAALGENDYLLASNYLNLSKSDNPTTIVRQFKQALDAGGRFQADLQINNTPEGNLTDQLPPSQENVGVIKVSDA
SIPLLLERVVSKEGEQYWQFSTDTLSSIPEAIENYEPTLVSRYTIDSLEGKKLFGYQLADLVAALMITISSFLFTYIAVW
LLYHLLEITYPRVRDVPLPLPDKVILPLAVVIMALILSEVMVYAGVSVTLREPVNRFAEIASWVAITWLLLRIIDALFTR
AVNLSYKKNYTERVSILGLLRKVVKALLLIFAVIVTFGNLGFDLTTGIAALGVGGLALALGAQKTIENLVGSVVVVADSP
VRIGDYCKFGTYEGTVIDIGIRSSRVRTLTRTIVTVPNGDFSSMQIENFTSRDMFRFLHQLYIKRTADIDVVFKMVKHLD
TFLDEHELTNQEWNQVNILELRQDCYIIQLQAYINATGIIEFYEKQDVLFVDLLMQVRKYDVEHALPTQQLIVKQPELQA
ELDHESKEGETVDKKADKKNAAADKPEAVNLSKDVDTIDDEQTADKPKDGLKKDMIDNRYKRIHKNRGYNLAKLKFKQVK
KSFRFPKI

Sequences:

>Translated_648_residues
MRFVLFIKHRLNTTTVPSLSMSLMKLPLIVITLLVAMALSILSQPSALAAETSILGVGGTKTEEGDGTSIPDSFGRDTPR
HTVQGFIAALGENDYLLASNYLNLSKSDNPTTIVRQFKQALDAGGRFQADLQINNTPEGNLTDQLPPSQENVGVIKVSDA
SIPLLLERVVSKEGEQYWQFSTDTLSSIPEAIENYEPTLVSRYTIDSLEGKKLFGYQLADLVAALMITISSFLFTYIAVW
LLYHLLEITYPRVRDVPLPLPDKVILPLAVVIMALILSEVMVYAGVSVTLREPVNRFAEIASWVAITWLLLRIIDALFTR
AVNLSYKKNYTERVSILGLLRKVVKALLLIFAVIVTFGNLGFDLTTGIAALGVGGLALALGAQKTIENLVGSVVVVADSP
VRIGDYCKFGTYEGTVIDIGIRSSRVRTLTRTIVTVPNGDFSSMQIENFTSRDMFRFLHQLYIKRTADIDVVFKMVKHLD
TFLDEHELTNQEWNQVNILELRQDCYIIQLQAYINATGIIEFYEKQDVLFVDLLMQVRKYDVEHALPTQQLIVKQPELQA
ELDHESKEGETVDKKADKKNAAADKPEAVNLSKDVDTIDDEQTADKPKDGLKKDMIDNRYKRIHKNRGYNLAKLKFKQVK
KSFRFPKI
>Mature_648_residues
MRFVLFIKHRLNTTTVPSLSMSLMKLPLIVITLLVAMALSILSQPSALAAETSILGVGGTKTEEGDGTSIPDSFGRDTPR
HTVQGFIAALGENDYLLASNYLNLSKSDNPTTIVRQFKQALDAGGRFQADLQINNTPEGNLTDQLPPSQENVGVIKVSDA
SIPLLLERVVSKEGEQYWQFSTDTLSSIPEAIENYEPTLVSRYTIDSLEGKKLFGYQLADLVAALMITISSFLFTYIAVW
LLYHLLEITYPRVRDVPLPLPDKVILPLAVVIMALILSEVMVYAGVSVTLREPVNRFAEIASWVAITWLLLRIIDALFTR
AVNLSYKKNYTERVSILGLLRKVVKALLLIFAVIVTFGNLGFDLTTGIAALGVGGLALALGAQKTIENLVGSVVVVADSP
VRIGDYCKFGTYEGTVIDIGIRSSRVRTLTRTIVTVPNGDFSSMQIENFTSRDMFRFLHQLYIKRTADIDVVFKMVKHLD
TFLDEHELTNQEWNQVNILELRQDCYIIQLQAYINATGIIEFYEKQDVLFVDLLMQVRKYDVEHALPTQQLIVKQPELQA
ELDHESKEGETVDKKADKKNAAADKPEAVNLSKDVDTIDDEQTADKPKDGLKKDMIDNRYKRIHKNRGYNLAKLKFKQVK
KSFRFPKI

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=184, Percent_Identity=29.8913043478261, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786670, Length=188, Percent_Identity=28.1914893617021, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787591, Length=219, Percent_Identity=22.8310502283105, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 72556; Mature: 72556

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS01246 UPF0003

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVLFIKHRLNTTTVPSLSMSLMKLPLIVITLLVAMALSILSQPSALAAETSILGVGGT
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEECCCC
KTEEGDGTSIPDSFGRDTPRHTVQGFIAALGENDYLLASNYLNLSKSDNPTTIVRQFKQA
CCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LDAGGRFQADLQINNTPEGNLTDQLPPSQENVGVIKVSDASIPLLLERVVSKEGEQYWQF
HCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHEE
STDTLSSIPEAIENYEPTLVSRYTIDSLEGKKLFGYQLADLVAALMITISSFLFTYIAVW
CHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYHLLEITYPRVRDVPLPLPDKVILPLAVVIMALILSEVMVYAGVSVTLREPVNRFAEI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHH
ASWVAITWLLLRIIDALFTRAVNLSYKKNYTERVSILGLLRKVVKALLLIFAVIVTFGNL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFDLTTGIAALGVGGLALALGAQKTIENLVGSVVVVADSPVRIGDYCKFGTYEGTVIDIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEECCCEECCCCCCEEEEEE
IRSSRVRTLTRTIVTVPNGDFSSMQIENFTSRDMFRFLHQLYIKRTADIDVVFKMVKHLD
CCCHHHHHHHHHEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TFLDEHELTNQEWNQVNILELRQDCYIIQLQAYINATGIIEFYEKQDVLFVDLLMQVRKY
HHHHHHHCCCCCCCCEEHEECCCCEEEEEEEEHHCCCHHEEECCCCCHHHHHHHHHHHHH
DVEHALPTQQLIVKQPELQAELDHESKEGETVDKKADKKNAAADKPEAVNLSKDVDTIDD
HHHHCCCHHHHHHCCCCHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
EQTADKPKDGLKKDMIDNRYKRIHKNRGYNLAKLKFKQVKKSFRFPKI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRFVLFIKHRLNTTTVPSLSMSLMKLPLIVITLLVAMALSILSQPSALAAETSILGVGGT
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEECCCC
KTEEGDGTSIPDSFGRDTPRHTVQGFIAALGENDYLLASNYLNLSKSDNPTTIVRQFKQA
CCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
LDAGGRFQADLQINNTPEGNLTDQLPPSQENVGVIKVSDASIPLLLERVVSKEGEQYWQF
HCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHEE
STDTLSSIPEAIENYEPTLVSRYTIDSLEGKKLFGYQLADLVAALMITISSFLFTYIAVW
CHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYHLLEITYPRVRDVPLPLPDKVILPLAVVIMALILSEVMVYAGVSVTLREPVNRFAEI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHH
ASWVAITWLLLRIIDALFTRAVNLSYKKNYTERVSILGLLRKVVKALLLIFAVIVTFGNL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFDLTTGIAALGVGGLALALGAQKTIENLVGSVVVVADSPVRIGDYCKFGTYEGTVIDIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEECCCEECCCCCCEEEEEE
IRSSRVRTLTRTIVTVPNGDFSSMQIENFTSRDMFRFLHQLYIKRTADIDVVFKMVKHLD
CCCHHHHHHHHHEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TFLDEHELTNQEWNQVNILELRQDCYIIQLQAYINATGIIEFYEKQDVLFVDLLMQVRKY
HHHHHHHCCCCCCCCEEHEECCCCEEEEEEEEHHCCCHHEEECCCCCHHHHHHHHHHHHH
DVEHALPTQQLIVKQPELQAELDHESKEGETVDKKADKKNAAADKPEAVNLSKDVDTIDD
HHHHCCCHHHHHHCCCCHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
EQTADKPKDGLKKDMIDNRYKRIHKNRGYNLAKLKFKQVKKSFRFPKI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]