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The map label for this gene is yiaY [H]

Identifier: 93006254

GI number: 93006254

Start: 1754899

End: 1756224

Strand: Reverse

Name: yiaY [H]

Synonym: Pcryo_1428

Alternate gene names: 93006254

Gene position: 1756224-1754899 (Counterclockwise)

Preceding gene: 93006255

Following gene: 93006253

Centisome position: 57.4

GC content: 44.42

Gene sequence:

>1326_bases
ATGAAAAAACAAAATAGTATTGCTAAATTAGTAAGTAATAAGTTAGTAAGTACCGATGGATTACAGCATGCTGGCTATTT
AGCCGTTGCCAAGACACGCGCCAAAGTACTAAAAGCCTTTGCTTATGTTATCCCGATTAGAAGACCGATGTTATTCGTCG
GCGAAAGCTCTTGTGATGAGCTATGCGACATGCTTATTAATGAAGGTAGCACCAATGTCTTTATCGTCACTGATGCGGTA
TTGAATAAGCTTGGTATACCTGCAAAAGTCACTGATTATCTAGATAGCAAAAATATCCGCTATAAAGTCTATGACGGTAT
TACGCCAGACCCTACTTTTAAAGTGGTTGAAGAAGGGCTACGCATCTCCGTTGATGCTAAATGCGATTCTATTATTGCTA
TCGGCGGCGGCTCTGTGATTGATGCAGCTAAAATGATTGCTATGTCACAAGGTAACAACTGCAAGCCGCAGCAACTTATC
GGCATTCTTAAAGCACGAAAGCCTTCTGTACCGCTGTACTGTGTGCCTACAACTGCGGGTACTGGTTCGGAAGCGACACT
TGGTGCAGTTGTATCAGATGATAAAACCCATCAAAAAGCACTATCTATCGACCCAAGAATGGTGCCATTAGCCGCCGCTA
TTGACCCAGTTATTATGAAAGGGATGCCGGCTCATATCACAGCGGATACGGGTATCGATGTGTTGACCCACGCCTTAGAA
GCTTGGATGAGTGCTAATGCGAGCGTCGAGACCGACTATTATGCGGCTTCTGCGGTGAAGTCAGTTATGCAGAATCTGCC
AGTAGTATATAAAGACGGCGGCAATCTCAAAGCCAGAGAAGCAATGGGTATTGCCGCTCACTACGGCGGTATTGCCTTTA
ATAAAGCGGGCCTTGGCTATGTCCATGCCATCGCTCATCAGCTTGGTGCGTATTATAGTATTCCGCATGGTCGCGCCAAT
GCCATCGTGTTACCTTATGTACTTGATGTCAATCGTCAAGCAAGCAAAAAGAGACTAGCAGATCTGGCTAGAAAAACGGG
TATGGTTAAGGATGGTCAAGCCGGCAAGAGTGATGCTGTGATTGCAGATAATCTGATTGCGCAAGTTCGCGAATTGATCG
CTACTTTAAATATTGATCCAACGGTTAAAGGTATGAAAACCACTGACTTTGATAGCATTGCTAAAGCCGCAGCTAAAGAA
GTCAGCGATACTTATGCGGTGCCAACGTATCTGTCAGCATCTGAAATCAAGAGCATTTTAACGAAGATTCAGCAAGCCAG
TGATGAGCATGCCGATACTGATGTTAAGAGCGATAAAGTTGCATAG

Upstream 100 bases:

>100_bases
ACCTAGTCCTATGTATATTATTTGAACCTTGATTTATTCGGTTAGTTCAAACGGTCATTATTACCATTAAAAGCATCATT
AAAAAAGGATTTTTATACCC

Downstream 100 bases:

>100_bases
ATGATTTGCTAAATGAATAACCTAGTCATGAATTAATAGAAAGCTTATTATCGAAAGGTAATAAGCTTTTTTTATGGCCA
TTCATTAAATATGGTGTATA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKKQNSIAKLVSNKLVSTDGLQHAGYLAVAKTRAKVLKAFAYVIPIRRPMLFVGESSCDELCDMLINEGSTNVFIVTDAV
LNKLGIPAKVTDYLDSKNIRYKVYDGITPDPTFKVVEEGLRISVDAKCDSIIAIGGGSVIDAAKMIAMSQGNNCKPQQLI
GILKARKPSVPLYCVPTTAGTGSEATLGAVVSDDKTHQKALSIDPRMVPLAAAIDPVIMKGMPAHITADTGIDVLTHALE
AWMSANASVETDYYAASAVKSVMQNLPVVYKDGGNLKAREAMGIAAHYGGIAFNKAGLGYVHAIAHQLGAYYSIPHGRAN
AIVLPYVLDVNRQASKKRLADLARKTGMVKDGQAGKSDAVIADNLIAQVRELIATLNIDPTVKGMKTTDFDSIAKAAAKE
VSDTYAVPTYLSASEIKSILTKIQQASDEHADTDVKSDKVA

Sequences:

>Translated_441_residues
MKKQNSIAKLVSNKLVSTDGLQHAGYLAVAKTRAKVLKAFAYVIPIRRPMLFVGESSCDELCDMLINEGSTNVFIVTDAV
LNKLGIPAKVTDYLDSKNIRYKVYDGITPDPTFKVVEEGLRISVDAKCDSIIAIGGGSVIDAAKMIAMSQGNNCKPQQLI
GILKARKPSVPLYCVPTTAGTGSEATLGAVVSDDKTHQKALSIDPRMVPLAAAIDPVIMKGMPAHITADTGIDVLTHALE
AWMSANASVETDYYAASAVKSVMQNLPVVYKDGGNLKAREAMGIAAHYGGIAFNKAGLGYVHAIAHQLGAYYSIPHGRAN
AIVLPYVLDVNRQASKKRLADLARKTGMVKDGQAGKSDAVIADNLIAQVRELIATLNIDPTVKGMKTTDFDSIAKAAAKE
VSDTYAVPTYLSASEIKSILTKIQQASDEHADTDVKSDKVA
>Mature_441_residues
MKKQNSIAKLVSNKLVSTDGLQHAGYLAVAKTRAKVLKAFAYVIPIRRPMLFVGESSCDELCDMLINEGSTNVFIVTDAV
LNKLGIPAKVTDYLDSKNIRYKVYDGITPDPTFKVVEEGLRISVDAKCDSIIAIGGGSVIDAAKMIAMSQGNNCKPQQLI
GILKARKPSVPLYCVPTTAGTGSEATLGAVVSDDKTHQKALSIDPRMVPLAAAIDPVIMKGMPAHITADTGIDVLTHALE
AWMSANASVETDYYAASAVKSVMQNLPVVYKDGGNLKAREAMGIAAHYGGIAFNKAGLGYVHAIAHQLGAYYSIPHGRAN
AIVLPYVLDVNRQASKKRLADLARKTGMVKDGQAGKSDAVIADNLIAQVRELIATLNIDPTVKGMKTTDFDSIAKAAAKE
VSDTYAVPTYLSASEIKSILTKIQQASDEHADTDVKSDKVA

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=356, Percent_Identity=28.0898876404494, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI48994951, Length=369, Percent_Identity=39.2953929539295, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1789163, Length=357, Percent_Identity=35.5742296918768, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI87082107, Length=383, Percent_Identity=32.8981723237598, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787493, Length=390, Percent_Identity=33.5897435897436, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789386, Length=309, Percent_Identity=26.8608414239482, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=386, Percent_Identity=25.6476683937824, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321181, Length=385, Percent_Identity=34.2857142857143, Blast_Score=223, Evalue=7e-59,
Organism=Drosophila melanogaster, GI24657991, Length=405, Percent_Identity=24.6913580246914, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 46934; Mature: 46934

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQNSIAKLVSNKLVSTDGLQHAGYLAVAKTRAKVLKAFAYVIPIRRPMLFVGESSCDE
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LCDMLINEGSTNVFIVTDAVLNKLGIPAKVTDYLDSKNIRYKVYDGITPDPTFKVVEEGL
HHHHHHCCCCCEEEEEEHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCC
RISVDAKCDSIIAIGGGSVIDAAKMIAMSQGNNCKPQQLIGILKARKPSVPLYCVPTTAG
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCC
TGSEATLGAVVSDDKTHQKALSIDPRMVPLAAAIDPVIMKGMPAHITADTGIDVLTHALE
CCCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHH
AWMSANASVETDYYAASAVKSVMQNLPVVYKDGGNLKAREAMGIAAHYGGIAFNKAGLGY
HHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHCCCEEECCCCCHH
VHAIAHQLGAYYSIPHGRANAIVLPYVLDVNRQASKKRLADLARKTGMVKDGQAGKSDAV
HHHHHHHHCCEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCH
IADNLIAQVRELIATLNIDPTVKGMKTTDFDSIAKAAAKEVSDTYAVPTYLSASEIKSIL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TKIQQASDEHADTDVKSDKVA
HHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKQNSIAKLVSNKLVSTDGLQHAGYLAVAKTRAKVLKAFAYVIPIRRPMLFVGESSCDE
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LCDMLINEGSTNVFIVTDAVLNKLGIPAKVTDYLDSKNIRYKVYDGITPDPTFKVVEEGL
HHHHHHCCCCCEEEEEEHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCC
RISVDAKCDSIIAIGGGSVIDAAKMIAMSQGNNCKPQQLIGILKARKPSVPLYCVPTTAG
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCC
TGSEATLGAVVSDDKTHQKALSIDPRMVPLAAAIDPVIMKGMPAHITADTGIDVLTHALE
CCCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHH
AWMSANASVETDYYAASAVKSVMQNLPVVYKDGGNLKAREAMGIAAHYGGIAFNKAGLGY
HHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHCCCEEECCCCCHH
VHAIAHQLGAYYSIPHGRANAIVLPYVLDVNRQASKKRLADLARKTGMVKDGQAGKSDAV
HHHHHHHHCCEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCH
IADNLIAQVRELIATLNIDPTVKGMKTTDFDSIAKAAAKEVSDTYAVPTYLSASEIKSIL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TKIQQASDEHADTDVKSDKVA
HHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]