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The map label for this gene is yceE [C]

Identifier: 93006105

GI number: 93006105

Start: 1549683

End: 1550996

Strand: Reverse

Name: yceE [C]

Synonym: Pcryo_1277

Alternate gene names: 93006105

Gene position: 1550996-1549683 (Counterclockwise)

Preceding gene: 93006106

Following gene: 93006104

Centisome position: 50.69

GC content: 44.22

Gene sequence:

>1314_bases
ATGAGCTATCGAATTATGGTGGCAATCGTCTTATGTTGTCACTACCTGTCCGCGTTTTCTGCGTTAGGTATGCCTTTGTT
TTTACCAATCATGCTCCAAGAGCTAAATGCGCCATTGCAATCAGGCTGGGTTGGTTTGCTGTTTATATTACCGACTCTCA
TGACTGCCATCGCTGCCAGATACTGGGGACGTTTTGCCGATACATATGGTCGCAAAACATCCTTGTTGCGAGCGGAGTTG
GGGTTGGCAGTGGGGTTTTTAATATGCGGATTTTCTCAGTCTTTATGGCAGCTCGTCATAGGGCTGAGCGTTCAGGGGCT
TTTTGGTGGGACAATGGCTGCCTCAAACGCCTATTTAGCCACCAGTATCACTGATAAAAACGCCTTAAAACAGGTGTTAA
ATTTCACTCAATTCTCAGCACGACTTGCCCTGATTACGGCCCCGATTGGGCTGGGTTTTTTGGTACACCATTACGAGGTG
TTAAGTTTGTATCGCGTGCTTGCCATCCTGCCGCTCTTAGCATTACTACTCAGCTTTTTGTTAAAGAAAGACATTATCAA
AGCAGGCAATATCGGCACAACCGCAAATACTACCGAATTGCCAAAAGCATCTACAAAAACCAAAACCAAAACCAAAACCA
AAACCAAAACCAACAACAGTAACAGTAACAGTAACAGTAACAGTAACAGTAACAGTAACAAAGCTAAAAGCGATAAAAAG
AAGACTCAGCACTCAGTGCAAGCAATAACGGGCACAGCTTTTTTCGCCAATCCTTATCTGTTTATATCGGTGCTGCAGTT
TTTCTTGGCCTTTTGTATGGTAGCGACTTTCCCCTATTTTTTGCCATTTGCCAAAACTTTTGAGCTGAGCACCTCTCAAA
TAGGACAGTTATATGCCATGCCTCATGTCATGTATCTGATCTGTCAGCTGCTCTATGGACGTATCAGCCAACGCCTGCCA
GCAATGTCCTTAAGCCTTGGCTTTACGGTATTAGCAAGTGCGGTTTTGCTGCATTTGACGGATTATCTTCCCCTGATTTG
GTTGGCTAGGATGTTATTTGGCGTTGGTATGTTTATGTGTTATCAAAGCCTGCATGCGCAAATGGCGGATACCAATCAGT
CTAAGCATAGCGGCAAAATATTCTCTCGCTATGATGCGCTAGCAAAATGGGGCGGCGTGCTAGCAGGATTGTCGGTCACT
TTATTTGTACCGATGTTTGGTTTGCTCTCTCCGTTTGTTCTCTCAGCAATGATGGCAGTTATCGCGATAATAACCATCAA
AATGTATCAAGCAAAACAGCGCAAGATTGTGTAA

Upstream 100 bases:

>100_bases
TGTCAAAAGAGCAGTCTGGCGCGAGCGATATCAATAAGTTCTATGGCAAATCAGCACCCAACACCTTAAAACTTATGCAG
CAACACAAGCAGGACTCCTA

Downstream 100 bases:

>100_bases
AGAGCACTACAGACAACAATCACTCTAAAAGCATCTAAAAAAGACTTCACTTATGAAACCAAACTATTCACTATCGAACA
ATACGATGCCAAATTTTCTA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: Facilitator Superfamily Protein; Multi-Drug Efflux Pump Homolog PvsC; Efflux Protein; Multidrug Resistance Protein; Vibrioferrin Membrane-Spanning Transport Protein PvsC; Transporter MFS Superfamily; Multidrug Resistance Efflux Pump

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSYRIMVAIVLCCHYLSAFSALGMPLFLPIMLQELNAPLQSGWVGLLFILPTLMTAIAARYWGRFADTYGRKTSLLRAEL
GLAVGFLICGFSQSLWQLVIGLSVQGLFGGTMAASNAYLATSITDKNALKQVLNFTQFSARLALITAPIGLGFLVHHYEV
LSLYRVLAILPLLALLLSFLLKKDIIKAGNIGTTANTTELPKASTKTKTKTKTKTKTNNSNSNSNSNSNSNSNKAKSDKK
KTQHSVQAITGTAFFANPYLFISVLQFFLAFCMVATFPYFLPFAKTFELSTSQIGQLYAMPHVMYLICQLLYGRISQRLP
AMSLSLGFTVLASAVLLHLTDYLPLIWLARMLFGVGMFMCYQSLHAQMADTNQSKHSGKIFSRYDALAKWGGVLAGLSVT
LFVPMFGLLSPFVLSAMMAVIAIITIKMYQAKQRKIV

Sequences:

>Translated_437_residues
MSYRIMVAIVLCCHYLSAFSALGMPLFLPIMLQELNAPLQSGWVGLLFILPTLMTAIAARYWGRFADTYGRKTSLLRAEL
GLAVGFLICGFSQSLWQLVIGLSVQGLFGGTMAASNAYLATSITDKNALKQVLNFTQFSARLALITAPIGLGFLVHHYEV
LSLYRVLAILPLLALLLSFLLKKDIIKAGNIGTTANTTELPKASTKTKTKTKTKTKTNNSNSNSNSNSNSNSNKAKSDKK
KTQHSVQAITGTAFFANPYLFISVLQFFLAFCMVATFPYFLPFAKTFELSTSQIGQLYAMPHVMYLICQLLYGRISQRLP
AMSLSLGFTVLASAVLLHLTDYLPLIWLARMLFGVGMFMCYQSLHAQMADTNQSKHSGKIFSRYDALAKWGGVLAGLSVT
LFVPMFGLLSPFVLSAMMAVIAIITIKMYQAKQRKIV
>Mature_436_residues
SYRIMVAIVLCCHYLSAFSALGMPLFLPIMLQELNAPLQSGWVGLLFILPTLMTAIAARYWGRFADTYGRKTSLLRAELG
LAVGFLICGFSQSLWQLVIGLSVQGLFGGTMAASNAYLATSITDKNALKQVLNFTQFSARLALITAPIGLGFLVHHYEVL
SLYRVLAILPLLALLLSFLLKKDIIKAGNIGTTANTTELPKASTKTKTKTKTKTKTNNSNSNSNSNSNSNSNKAKSDKKK
TQHSVQAITGTAFFANPYLFISVLQFFLAFCMVATFPYFLPFAKTFELSTSQIGQLYAMPHVMYLICQLLYGRISQRLPA
MSLSLGFTVLASAVLLHLTDYLPLIWLARMLFGVGMFMCYQSLHAQMADTNQSKHSGKIFSRYDALAKWGGVLAGLSVTL
FVPMFGLLSPFVLSAMMAVIAIITIKMYQAKQRKIV

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787291, Length=184, Percent_Identity=28.2608695652174, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48061; Mature: 47930

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRIMVAIVLCCHYLSAFSALGMPLFLPIMLQELNAPLQSGWVGLLFILPTLMTAIAAR
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YWGRFADTYGRKTSLLRAELGLAVGFLICGFSQSLWQLVIGLSVQGLFGGTMAASNAYLA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHCCCCEEE
TSITDKNALKQVLNFTQFSARLALITAPIGLGFLVHHYEVLSLYRVLAILPLLALLLSFL
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKDIIKAGNIGTTANTTELPKASTKTKTKTKTKTKTNNSNSNSNSNSNSNSNKAKSDKK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
KTQHSVQAITGTAFFANPYLFISVLQFFLAFCMVATFPYFLPFAKTFELSTSQIGQLYAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PHVMYLICQLLYGRISQRLPAMSLSLGFTVLASAVLLHLTDYLPLIWLARMLFGVGMFMC
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQSLHAQMADTNQSKHSGKIFSRYDALAKWGGVLAGLSVTLFVPMFGLLSPFVLSAMMAV
HHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIITIKMYQAKQRKIV
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYRIMVAIVLCCHYLSAFSALGMPLFLPIMLQELNAPLQSGWVGLLFILPTLMTAIAAR
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YWGRFADTYGRKTSLLRAELGLAVGFLICGFSQSLWQLVIGLSVQGLFGGTMAASNAYLA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHCCCCEEE
TSITDKNALKQVLNFTQFSARLALITAPIGLGFLVHHYEVLSLYRVLAILPLLALLLSFL
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKDIIKAGNIGTTANTTELPKASTKTKTKTKTKTKTNNSNSNSNSNSNSNSNKAKSDKK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
KTQHSVQAITGTAFFANPYLFISVLQFFLAFCMVATFPYFLPFAKTFELSTSQIGQLYAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PHVMYLICQLLYGRISQRLPAMSLSLGFTVLASAVLLHLTDYLPLIWLARMLFGVGMFMC
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQSLHAQMADTNQSKHSGKIFSRYDALAKWGGVLAGLSVTLFVPMFGLLSPFVLSAMMAV
HHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIITIKMYQAKQRKIV
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA