Click here to switch to the map view.

The map label for this gene is dapA [H]

Identifier: 93006045

GI number: 93006045

Start: 1475444

End: 1476325

Strand: Reverse

Name: dapA [H]

Synonym: Pcryo_1217

Alternate gene names: 93006045

Gene position: 1476325-1475444 (Counterclockwise)

Preceding gene: 93006046

Following gene: 93006044

Centisome position: 48.25

GC content: 47.17

Gene sequence:

>882_bases
ATGAACATAAATGGAATTTTAGTCCCAATCGTCACCCCTTTTGACAATAACGGCGACGTTGATGCGCAAAAATTAACGAC
ACTGGTCGAAGCCTTTATCGACAAAGGCGTAGCCGGTATCGTCGCTTGCGGTACCACAGGGGAATACTATACGTTTTCGG
CAGCGGAGCGCGAGCTGGTATTAACCACTATCGCTGAAGCCGCAAAAAATAAAGGCGCTGAGAATAAAGTCACTCTGATT
GCTGGTATCAACAGCTTATCGACTGACCACTCTATTGAGCTTGCCGCACAAGCCAAAGCCTTAGGTTATGACGGCCTGAT
GCTGTCTGCCACCCCTTATAGCTTACCTGAGCAAGATGGCATCATCGCTCACTTCGAAAAAGTCGCGGATGCTAGTGAGC
TGCCGATTATTATGTACAACTTCCCTGCTCGTGTTGGCGTTGCCATTGAATTTGACACCGTCGCTCATCTAGCTAAGCAC
CCTAACATCGTCGGCGTAAAAGAAAGCAGCGGCGACTTTAGTCATGCGCTACGCATGCTGCAAGCTAATTTTGATGACTT
TGAGGTGGTTTGTGGCTGTGATGATCAGCCGGTTGATTTCTTCTTTTGGGGTGCAAAAAGCTGGATTGCAGGCGCAGCCA
ACGTTTTCCCAGCAGAGCAAGTTTCATTATTTAATGCCACTCAGCAAGGGGACTGGGATAAAGCCAAGCAAATTATGAGC
GAGATTTATCCTGCTATTCATTCTATGGAATCTGGCAACTACAACCAGAAAGCCAAAGCGGGCTGCTTAAAAGGCAGCAT
GGATGTTGGCTCAGTGCGTGTGCCATTAACTGATATGCCAGCAGACGAAAAAGCAGAGTTTTTAGCATTATTGGCTAAAT
AG

Upstream 100 bases:

>100_bases
CTTATTAAACGTTTATGAACTAAGCAAAAACCAACCGATTCAGCATTGAATCATCACCCGTTAAATCACCAACAATATCA
ACCCCAATAAGGATAGTCTC

Downstream 100 bases:

>100_bases
CACTCAGCTCAGCTTAGTAAAAACAATGTTAAGGATAACCAATGCTAAATTTGATGCCGTATTCAAATCTCGAATCAATG
GCATCAAACTTAGCAGATAA

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNINGILVPIVTPFDNNGDVDAQKLTTLVEAFIDKGVAGIVACGTTGEYYTFSAAERELVLTTIAEAAKNKGAENKVTLI
AGINSLSTDHSIELAAQAKALGYDGLMLSATPYSLPEQDGIIAHFEKVADASELPIIMYNFPARVGVAIEFDTVAHLAKH
PNIVGVKESSGDFSHALRMLQANFDDFEVVCGCDDQPVDFFFWGAKSWIAGAANVFPAEQVSLFNATQQGDWDKAKQIMS
EIYPAIHSMESGNYNQKAKAGCLKGSMDVGSVRVPLTDMPADEKAEFLALLAK

Sequences:

>Translated_293_residues
MNINGILVPIVTPFDNNGDVDAQKLTTLVEAFIDKGVAGIVACGTTGEYYTFSAAERELVLTTIAEAAKNKGAENKVTLI
AGINSLSTDHSIELAAQAKALGYDGLMLSATPYSLPEQDGIIAHFEKVADASELPIIMYNFPARVGVAIEFDTVAHLAKH
PNIVGVKESSGDFSHALRMLQANFDDFEVVCGCDDQPVDFFFWGAKSWIAGAANVFPAEQVSLFNATQQGDWDKAKQIMS
EIYPAIHSMESGNYNQKAKAGCLKGSMDVGSVRVPLTDMPADEKAEFLALLAK
>Mature_293_residues
MNINGILVPIVTPFDNNGDVDAQKLTTLVEAFIDKGVAGIVACGTTGEYYTFSAAERELVLTTIAEAAKNKGAENKVTLI
AGINSLSTDHSIELAAQAKALGYDGLMLSATPYSLPEQDGIIAHFEKVADASELPIIMYNFPARVGVAIEFDTVAHLAKH
PNIVGVKESSGDFSHALRMLQANFDDFEVVCGCDDQPVDFFFWGAKSWIAGAANVFPAEQVSLFNATQQGDWDKAKQIMS
EIYPAIHSMESGNYNQKAKAGCLKGSMDVGSVRVPLTDMPADEKAEFLALLAK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=297, Percent_Identity=29.2929292929293, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI13540533, Length=240, Percent_Identity=27.5, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1788823, Length=277, Percent_Identity=29.9638989169675, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789620, Length=294, Percent_Identity=29.9319727891156, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082415, Length=254, Percent_Identity=29.1338582677165, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786463, Length=289, Percent_Identity=28.3737024221453, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31429; Mature: 31429

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINGILVPIVTPFDNNGDVDAQKLTTLVEAFIDKGVAGIVACGTTGEYYTFSAAERELV
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCHHH
LTTIAEAAKNKGAENKVTLIAGINSLSTDHSIELAAQAKALGYDGLMLSATPYSLPEQDG
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEHHHHCCCCCEEEECCCCCCCCCCC
IIAHFEKVADASELPIIMYNFPARVGVAIEFDTVAHLAKHPNIVGVKESSGDFSHALRML
HHHHHHHHCCCCCCCEEEEECCCEEEEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
QANFDDFEVVCGCDDQPVDFFFWGAKSWIAGAANVFPAEQVSLFNATQQGDWDKAKQIMS
HCCCCCEEEEECCCCCCCEEEEECCHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHH
EIYPAIHSMESGNYNQKAKAGCLKGSMDVGSVRVPLTDMPADEKAEFLALLAK
HHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNINGILVPIVTPFDNNGDVDAQKLTTLVEAFIDKGVAGIVACGTTGEYYTFSAAERELV
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCHHH
LTTIAEAAKNKGAENKVTLIAGINSLSTDHSIELAAQAKALGYDGLMLSATPYSLPEQDG
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEHHHHCCCCCEEEECCCCCCCCCCC
IIAHFEKVADASELPIIMYNFPARVGVAIEFDTVAHLAKHPNIVGVKESSGDFSHALRML
HHHHHHHHCCCCCCCEEEEECCCEEEEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
QANFDDFEVVCGCDDQPVDFFFWGAKSWIAGAANVFPAEQVSLFNATQQGDWDKAKQIMS
HCCCCCEEEEECCCCCCCEEEEECCHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHH
EIYPAIHSMESGNYNQKAKAGCLKGSMDVGSVRVPLTDMPADEKAEFLALLAK
HHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA