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The map label for this gene is aspS [H]

Identifier: 93006011

GI number: 93006011

Start: 1430984

End: 1432810

Strand: Reverse

Name: aspS [H]

Synonym: Pcryo_1183

Alternate gene names: 93006011

Gene position: 1432810-1430984 (Counterclockwise)

Preceding gene: 93006017

Following gene: 93006010

Centisome position: 46.83

GC content: 44.66

Gene sequence:

>1827_bases
ATGACGCATAGCGAATACCGAGACGAATATTGCGGAGCCGTAACCGAAAGCTTAATTGAGCAAACCATTAGTGTCGTAGG
CTGGGTACATCGTCGTCGCGATCACGGTGGCGTGATTTTCTTAGACATGCGTGACCGCGCTGGTATCTTGCAGGTCGTTG
TCGATCCTGATACCCCAGAAGCGTTCGCTATTGCTGATGCGGTACGTCCTGAATATGTAATAAAAATCACAGGTCGTGTC
CGTCAACGCTACGCGGGCACTGAAAACGCAAATATGACCAGTGGTCATATCGAGCTGTTGGCCAAAGAAATTGAAGTGCT
GGCAAAATCTGAAACCCCGCCATTCCCATTGAATGATGAGAAAAGTACGGTATCAGAAGATCTACGTCTCAAATATCGCT
ATCTTGATATGCGCCGTCCACAAATGCAAGATCGTATGGTATTCCGTGCTAAAGCTACCTCAGCGATTCGTCGTTATTTA
GATGACCATGGCTTTTTAGATGTAGAAACCCCTATCTTGACTCGTGCAACGCCAGAAGGTGCTCGTGATTATCTTGTGCC
TTCACGTACGCGTCCGGGTAACTTCTTTGCCTTACCGCAGTCGCCACAGCTGTTTAAACAGTTATTGATGGTCGCAGGTT
TTGACCGCTATTATCAAATCGCTAAGTGCTTCCGTGATGAAGATTTACGTGCGGATCGTCAGCCTGAATTTACCCAAGTC
GATATTGAGACTTCTTTCTTAAATGAAGAAGAAATCATGAATATCAACGAAGGTCTGATTAAGCATGTCTTTAAGACGAT
GATGGACGTTGAATTTGAACAGTTCCCACGTATGACTTATGCTGAAGCCATGCGTGATTATGCCTCAGACAAGCCTGACC
TACGTATTCCGCTTAAATTGATTGACGTTGCAGACTTAATGAAAGACGTTGATTTTAAAGTGTTTGCCGGTCCTGCTAAC
GATCCTAAAGGTCGTGTTGCTGCCCTACGTATACCAGGCGGTGCTTCATTAAGCCGTAAACAAATCGATGCGTATACCAA
ATTCGTTAGTATCTATGGTGCACGTGGTTTGGCTTATATTAAAGTCAACGATGCCAGCAACATCAATAACGGCGTGGATA
AAGAATCTGGTCTACAGTCTCCTATCATTAAGAATATGACTGATGATGTATTGGTAAGCCTGATTGAGCGTACTGGTGCA
GAAAGCAACGATATTATCTTCTTTGGTGCGGATAAAGCCAGTGTGGTCAATGATGCCATCGGCGCCCTACGTCAAAAGAT
TGGTTTAGATTTAGAAATGACCACTTGTGAGTGGGCACCACTTTGGGTAACTGACTTTCCGATGTTTGAAGAAACTGAAG
ATGGTCGCTGGACCTCAATGCATCATCCATTTACTAAGCCAAAAGGTTCGGTTGAAGAATTAAAAACCAATCCTGAATCT
GCCCTTTCTATCGCTTATGATATGGTATTAAACGGTACTGAAGTGGGTGGTGGTAGTTTACGTATCAATACACTTGAGAT
GCAAACAGCCGTATTTGAAGCATTGGGTATTGATGATCAGGAAGCAGAAGACAAATTTGGCTTCTTGCTTGATGCGTTAA
AATTTGGTGCGCCGCCACATGGTGGCTTGGCATTTGGTTTGGACCGCTTAATCATGCTTATGGTAGGCGCAAGCTCTATC
CGTGACGTGATTGCCTTCCCAAAAACCAAAACTGCTGAATGTCCATTGACGCAAGCACCGGCTGAGGTGAATACTAAGCA
GCTACGTGAGCTTGGTATCCGTGTCCGTGAAAAAGTACAAGCTGACACCAGTAAGTCTGCTGAATAA

Upstream 100 bases:

>100_bases
TTTGCGCTTCTTTTAACTAAACTAGTTATTATCTAAAAGAAGCGCAACGATGGCTGCATTATTGTATTTCGAATTGGGCT
GACAACTGGATAATTATATT

Downstream 100 bases:

>100_bases
ATAGTCTGATCATGCGAAGCTATTTTTTACAGTGCCTGTTATGTGATTCATTACTGTGTGAATGGTCATGAATCCGTATC
ATATTTTCAAAATCGTGCCA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MTHSEYRDEYCGAVTESLIEQTISVVGWVHRRRDHGGVIFLDMRDRAGILQVVVDPDTPEAFAIADAVRPEYVIKITGRV
RQRYAGTENANMTSGHIELLAKEIEVLAKSETPPFPLNDEKSTVSEDLRLKYRYLDMRRPQMQDRMVFRAKATSAIRRYL
DDHGFLDVETPILTRATPEGARDYLVPSRTRPGNFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQV
DIETSFLNEEEIMNINEGLIKHVFKTMMDVEFEQFPRMTYAEAMRDYASDKPDLRIPLKLIDVADLMKDVDFKVFAGPAN
DPKGRVAALRIPGGASLSRKQIDAYTKFVSIYGARGLAYIKVNDASNINNGVDKESGLQSPIIKNMTDDVLVSLIERTGA
ESNDIIFFGADKASVVNDAIGALRQKIGLDLEMTTCEWAPLWVTDFPMFEETEDGRWTSMHHPFTKPKGSVEELKTNPES
ALSIAYDMVLNGTEVGGGSLRINTLEMQTAVFEALGIDDQEAEDKFGFLLDALKFGAPPHGGLAFGLDRLIMLMVGASSI
RDVIAFPKTKTAECPLTQAPAEVNTKQLRELGIRVREKVQADTSKSAE

Sequences:

>Translated_608_residues
MTHSEYRDEYCGAVTESLIEQTISVVGWVHRRRDHGGVIFLDMRDRAGILQVVVDPDTPEAFAIADAVRPEYVIKITGRV
RQRYAGTENANMTSGHIELLAKEIEVLAKSETPPFPLNDEKSTVSEDLRLKYRYLDMRRPQMQDRMVFRAKATSAIRRYL
DDHGFLDVETPILTRATPEGARDYLVPSRTRPGNFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQV
DIETSFLNEEEIMNINEGLIKHVFKTMMDVEFEQFPRMTYAEAMRDYASDKPDLRIPLKLIDVADLMKDVDFKVFAGPAN
DPKGRVAALRIPGGASLSRKQIDAYTKFVSIYGARGLAYIKVNDASNINNGVDKESGLQSPIIKNMTDDVLVSLIERTGA
ESNDIIFFGADKASVVNDAIGALRQKIGLDLEMTTCEWAPLWVTDFPMFEETEDGRWTSMHHPFTKPKGSVEELKTNPES
ALSIAYDMVLNGTEVGGGSLRINTLEMQTAVFEALGIDDQEAEDKFGFLLDALKFGAPPHGGLAFGLDRLIMLMVGASSI
RDVIAFPKTKTAECPLTQAPAEVNTKQLRELGIRVREKVQADTSKSAE
>Mature_607_residues
THSEYRDEYCGAVTESLIEQTISVVGWVHRRRDHGGVIFLDMRDRAGILQVVVDPDTPEAFAIADAVRPEYVIKITGRVR
QRYAGTENANMTSGHIELLAKEIEVLAKSETPPFPLNDEKSTVSEDLRLKYRYLDMRRPQMQDRMVFRAKATSAIRRYLD
DHGFLDVETPILTRATPEGARDYLVPSRTRPGNFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQVD
IETSFLNEEEIMNINEGLIKHVFKTMMDVEFEQFPRMTYAEAMRDYASDKPDLRIPLKLIDVADLMKDVDFKVFAGPAND
PKGRVAALRIPGGASLSRKQIDAYTKFVSIYGARGLAYIKVNDASNINNGVDKESGLQSPIIKNMTDDVLVSLIERTGAE
SNDIIFFGADKASVVNDAIGALRQKIGLDLEMTTCEWAPLWVTDFPMFEETEDGRWTSMHHPFTKPKGSVEELKTNPESA
LSIAYDMVLNGTEVGGGSLRINTLEMQTAVFEALGIDDQEAEDKFGFLLDALKFGAPPHGGLAFGLDRLIMLMVGASSIR
DVIAFPKTKTAECPLTQAPAEVNTKQLRELGIRVREKVQADTSKSAE

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=614, Percent_Identity=38.4364820846906, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI5031815, Length=260, Percent_Identity=27.3076923076923, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI194272210, Length=260, Percent_Identity=27.3076923076923, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI45439306, Length=302, Percent_Identity=26.4900662251656, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI226491502, Length=263, Percent_Identity=27.3764258555133, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI4758762, Length=260, Percent_Identity=26.5384615384615, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1788173, Length=596, Percent_Identity=57.2147651006711, Blast_Score=713, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=294, Percent_Identity=25.1700680272109, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789256, Length=312, Percent_Identity=23.3974358974359, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082379, Length=179, Percent_Identity=30.1675977653631, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32566633, Length=620, Percent_Identity=34.3548387096774, Blast_Score=317, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI71994340, Length=264, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17535925, Length=264, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17535927, Length=264, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17551876, Length=269, Percent_Identity=25.2788104089219, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71984122, Length=288, Percent_Identity=26.3888888888889, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325153, Length=635, Percent_Identity=32.9133858267717, Blast_Score=286, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6320242, Length=265, Percent_Identity=24.5283018867925, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=241, Percent_Identity=28.6307053941909, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6321807, Length=250, Percent_Identity=26, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324256, Length=163, Percent_Identity=28.2208588957055, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584738, Length=622, Percent_Identity=35.5305466237942, Blast_Score=336, Evalue=3e-92,
Organism=Drosophila melanogaster, GI17136276, Length=280, Percent_Identity=26.7857142857143, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640849, Length=259, Percent_Identity=27.4131274131274, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24640851, Length=259, Percent_Identity=27.4131274131274, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19922416, Length=310, Percent_Identity=25.4838709677419, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 68177; Mature: 68046

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSEYRDEYCGAVTESLIEQTISVVGWVHRRRDHGGVIFLDMRDRAGILQVVVDPDTPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCC
AFAIADAVRPEYVIKITGRVRQRYAGTENANMTSGHIELLAKEIEVLAKSETPPFPLNDE
CEEHHHHCCCCEEEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
KSTVSEDLRLKYRYLDMRRPQMQDRMVFRAKATSAIRRYLDDHGFLDVETPILTRATPEG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCC
ARDYLVPSRTRPGNFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQV
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEE
DIETSFLNEEEIMNINEGLIKHVFKTMMDVEFEQFPRMTYAEAMRDYASDKPDLRIPLKL
EEEHHHCCHHHHHCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHH
IDVADLMKDVDFKVFAGPANDPKGRVAALRIPGGASLSRKQIDAYTKFVSIYGARGLAYI
HHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
KVNDASNINNGVDKESGLQSPIIKNMTDDVLVSLIERTGAESNDIIFFGADKASVVNDAI
EECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
GALRQKIGLDLEMTTCEWAPLWVTDFPMFEETEDGRWTSMHHPFTKPKGSVEELKTNPES
HHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHHCCHHH
ALSIAYDMVLNGTEVGGGSLRINTLEMQTAVFEALGIDDQEAEDKFGFLLDALKFGAPPH
HHHHHHHHHCCCCEECCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
GGLAFGLDRLIMLMVGASSIRDVIAFPKTKTAECPLTQAPAEVNTKQLRELGIRVREKVQ
CCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ADTSKSAE
HCCCCCCC
>Mature Secondary Structure 
THSEYRDEYCGAVTESLIEQTISVVGWVHRRRDHGGVIFLDMRDRAGILQVVVDPDTPE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCC
AFAIADAVRPEYVIKITGRVRQRYAGTENANMTSGHIELLAKEIEVLAKSETPPFPLNDE
CEEHHHHCCCCEEEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
KSTVSEDLRLKYRYLDMRRPQMQDRMVFRAKATSAIRRYLDDHGFLDVETPILTRATPEG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCC
ARDYLVPSRTRPGNFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQV
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEE
DIETSFLNEEEIMNINEGLIKHVFKTMMDVEFEQFPRMTYAEAMRDYASDKPDLRIPLKL
EEEHHHCCHHHHHCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHH
IDVADLMKDVDFKVFAGPANDPKGRVAALRIPGGASLSRKQIDAYTKFVSIYGARGLAYI
HHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
KVNDASNINNGVDKESGLQSPIIKNMTDDVLVSLIERTGAESNDIIFFGADKASVVNDAI
EECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
GALRQKIGLDLEMTTCEWAPLWVTDFPMFEETEDGRWTSMHHPFTKPKGSVEELKTNPES
HHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHHCCHHH
ALSIAYDMVLNGTEVGGGSLRINTLEMQTAVFEALGIDDQEAEDKFGFLLDALKFGAPPH
HHHHHHHHHCCCCEECCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
GGLAFGLDRLIMLMVGASSIRDVIAFPKTKTAECPLTQAPAEVNTKQLRELGIRVREKVQ
CCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ADTSKSAE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA