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The map label for this gene is kdsB

Identifier: 93005892

GI number: 93005892

Start: 1280293

End: 1281099

Strand: Direct

Name: kdsB

Synonym: Pcryo_1064

Alternate gene names: 93005892

Gene position: 1280293-1281099 (Clockwise)

Preceding gene: 93005891

Following gene: 93005893

Centisome position: 41.84

GC content: 43.99

Gene sequence:

>807_bases
ATGTCATCAGCCCTTATGCCCGTCAAAACTCATATCGTCATTCCTGCACGTTTAAAAAGTACGCGTTTACCTAACAAGCC
ATTATTAACCATTCATGGCAAGCCTATGATACTTTGGGTGGCTGAAAAAGCACGATTGGCGGATTTTGCCGATGATATGT
GTATTGCAACCGATGATGAATCGATTGCAAAAATTTGTCTAGATGCAGGTTTTGATGTGGTGATGACAAGCAGTGAACAT
GCTTCAGGCACGGACCGTTTGGCTGAAGTGGCTGCCATCAAAGGCTGGGCTGCCCATGATATAGTGGTTAATATGCAAGG
TGACGAACCACTAGTGCCGCCATTGTTGTTAGAGCAAGTTAAAACATTATTGGTACAAGATGCAGAGAGCGTCATGGCAA
CTTTATGTGAGCCAATCGAGGACTATGATACTTTTATGCGCCCATCCGTCGTTAAAGTGGTCAGTCAGACGTCCAATGAT
CAACAACGGGCGCTTTATTTTAGTCGCGCGCCGATTCCTTGTAATCGTGATGTGGTATTAACCAGTGAGAATAGTAAACA
GCCGCCAAAAAATGCCTATCGTCATCTAGGCTTATATGCTTATCGCGTCAGTTTGCTACAGCAATTTGTCCACTGCTCAC
AAACGCCGCTTGAAATACTGGAAAGCTTAGAGCAATTACGTGTGTTGGAAAATGGTGGACATATCGCCATTGCTAAAGCC
GCCTGCTCATTACCTGCAGGTGTCGATACGCAAGAAGATTTGGATCGTTTAAATGCCATGAGTTTGACAGATTTCCAAGA
TTATTAA

Upstream 100 bases:

>100_bases
ACAACAGCAATTGCAAACCTTGGACATCGATATAAGCATGAGAAAGCAATAATATAGCGTTTATCATATAAAGATTTAAA
AGGTTTTATAGGAACAGATT

Downstream 100 bases:

>100_bases
TGCGGAATAGCCTAAGCAATAAAAATACAGTTTCTATTGAAATAGTTTTAATTAAATTTTATAGCATTATTTTTATTCCA
AATTACTCTTAGAAATTATG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSSALMPVKTHIVIPARLKSTRLPNKPLLTIHGKPMILWVAEKARLADFADDMCIATDDESIAKICLDAGFDVVMTSSEH
ASGTDRLAEVAAIKGWAAHDIVVNMQGDEPLVPPLLLEQVKTLLVQDAESVMATLCEPIEDYDTFMRPSVVKVVSQTSND
QQRALYFSRAPIPCNRDVVLTSENSKQPPKNAYRHLGLYAYRVSLLQQFVHCSQTPLEILESLEQLRVLENGGHIAIAKA
ACSLPAGVDTQEDLDRLNAMSLTDFQDY

Sequences:

>Translated_268_residues
MSSALMPVKTHIVIPARLKSTRLPNKPLLTIHGKPMILWVAEKARLADFADDMCIATDDESIAKICLDAGFDVVMTSSEH
ASGTDRLAEVAAIKGWAAHDIVVNMQGDEPLVPPLLLEQVKTLLVQDAESVMATLCEPIEDYDTFMRPSVVKVVSQTSND
QQRALYFSRAPIPCNRDVVLTSENSKQPPKNAYRHLGLYAYRVSLLQQFVHCSQTPLEILESLEQLRVLENGGHIAIAKA
ACSLPAGVDTQEDLDRLNAMSLTDFQDY
>Mature_267_residues
SSALMPVKTHIVIPARLKSTRLPNKPLLTIHGKPMILWVAEKARLADFADDMCIATDDESIAKICLDAGFDVVMTSSEHA
SGTDRLAEVAAIKGWAAHDIVVNMQGDEPLVPPLLLEQVKTLLVQDAESVMATLCEPIEDYDTFMRPSVVKVVSQTSNDQ
QRALYFSRAPIPCNRDVVLTSENSKQPPKNAYRHLGLYAYRVSLLQQFVHCSQTPLEILESLEQLRVLENGGHIAIAKAA
CSLPAGVDTQEDLDRLNAMSLTDFQDY

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=248, Percent_Identity=44.3548387096774, Blast_Score=190, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_PSYCK (Q1QBV8)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_580329.1
- ProteinModelPortal:   Q1QBV8
- SMR:   Q1QBV8
- STRING:   Q1QBV8
- GeneID:   4035465
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_1064
- NMPDR:   fig|335284.3.peg.477
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- PhylomeDB:   Q1QBV8
- ProtClustDB:   PRK05450
- BioCyc:   PCRY335284:PCRYO_1064-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 29571; Mature: 29440

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSALMPVKTHIVIPARLKSTRLPNKPLLTIHGKPMILWVAEKARLADFADDMCIATDDE
CCCCCCEEEEEEEEECHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHCCCCEEECCCH
SIAKICLDAGFDVVMTSSEHASGTDRLAEVAAIKGWAAHDIVVNMQGDEPLVPPLLLEQV
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHH
KTLLVQDAESVMATLCEPIEDYDTFMRPSVVKVVSQTSNDQQRALYFSRAPIPCNRDVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHEEEEECCCCCCCCCEEE
TSENSKQPPKNAYRHLGLYAYRVSLLQQFVHCSQTPLEILESLEQLRVLENGGHIAIAKA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEE
ACSLPAGVDTQEDLDRLNAMSLTDFQDY
HHCCCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SSALMPVKTHIVIPARLKSTRLPNKPLLTIHGKPMILWVAEKARLADFADDMCIATDDE
CCCCCEEEEEEEEECHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHCCCCEEECCCH
SIAKICLDAGFDVVMTSSEHASGTDRLAEVAAIKGWAAHDIVVNMQGDEPLVPPLLLEQV
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHH
KTLLVQDAESVMATLCEPIEDYDTFMRPSVVKVVSQTSNDQQRALYFSRAPIPCNRDVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHEEEEECCCCCCCCCEEE
TSENSKQPPKNAYRHLGLYAYRVSLLQQFVHCSQTPLEILESLEQLRVLENGGHIAIAKA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEE
ACSLPAGVDTQEDLDRLNAMSLTDFQDY
HHCCCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA