Click here to switch to the map view.

The map label for this gene is emrB [C]

Identifier: 93005837

GI number: 93005837

Start: 1207506

End: 1209122

Strand: Reverse

Name: emrB [C]

Synonym: Pcryo_1009

Alternate gene names: 93005837

Gene position: 1209122-1207506 (Counterclockwise)

Preceding gene: 93005838

Following gene: 93005836

Centisome position: 39.52

GC content: 44.96

Gene sequence:

>1617_bases
ATGAGTACCGACTATCAGTTTAAGCCTCATGAACAGCCGTTTATGCTGGGCTCTCCTGCCACACCCGATCATCCTACTTA
TCGGAAAGTATTTTACTTACTAATCGGTATTTTTATCGGTATTACTGCCAGTTTTCAAAACGGTCTATTAGTCGCCAACC
TCTCTCAAATTCAAGGTGAGATGGGCTTAACCCCTGTTGAGGGTGGCTGGATATCAGTCGCTTACAATATGACCAATGCC
TGTATCACGGTACTGCTCTATAAAATTCGCCAACAGTTTGGTATGTCGTTATTTAGCAAAATCACCCTATTCTTTTTGCT
CTCAGCGACCAGTATGCAGTGGTTAGTCAGTAGTCATCTATTGAGCTCAACCACCGGAATTAGCATTGATCCTTATTATT
TAGAGCTGATTGCCCGTGGCTTTAGCGGCGTGGTTGCGAGTGCCATGACGGTATTGTCTATCTTTTATTGTTTGCAAGGC
ATGCCAGCAGCTCGGCGTATTAGTGGACTGATTTTGGGCTTTGGCTTGGTACAGTTTGGGGTGCCTTTATCTCGCATCAT
CTCGCCTTATCTTGCCGCCGATGGTCAACTTGAAGGCTTGTTTTTATTCCAAGTAGGCTTAGCTTTGATATGCTTTGGCT
TAATTAACCTTCTTGAGCTGCCACGCGGTAATATGGAAAGAGTCTTTGAAAAGCTGGATATTGTCAGCTTTGTTTTTTTT
GCGACTGGTCTTGCAGCATTGGCAGTGTTTTTGGTACAAGGGCGTATTTTATGGTGGACGACTCCTTGGCTCAGTTATCC
ACTGATTATTTCCGTCGTCACCATTTCTATTGCGTTGTGGATTGAAACCCATCGTAAAAATCCAATGCTACAAGTACGTT
GGATGCGCAGCCGGACGATTATCGCCTTTATGATAACGGGCGCTGTGATGCGTATCTTGCTGTCGGAGCAAAGCGTTGGC
GCGGCAGGGTTATTGGCTAACCTCGGTTATGGCAATGATCAGCTGATTGTGTTCTATGCCATTATTTTAGCCGCTAGTGC
GCTGGCATTGGTGCTTAGTATTTTTACGACCAATGCGATGGACCTGCGTCGACCGGTTATTTTTGCCGTGGCATTGATTG
CGATTGGTGCATGGATAGATACGGGTGTGTCACTGAATTCTACACCTGTCATGTTTTATTTTAGTCAGTTTATCATTGCG
TTTGCTGCCGTATATTTTATGGGACCGATGGTATTTGAAGGGATGTTTCGTGCCATTGCTAATGGACCTGCCTATATTAT
TAGCTTCTCGGTGATTTTTGGTATTTCGCAAACGGTTGGCGGTTTAGCAGGTGCCGCCGGTATTCAAGCCTTTACCACTA
TTCGCACGCAGATGCACTATGCAGATATGGTCAGCTCGATGACTGCTGGCAACCCTGCTCAAATGACCCAAATGCTGCAA
GGGATTCAGCGCCAAGCGACCGTTGCCGCTTATGATGATTTATTCTTTTTAATGGCAGTGAGCGCTACGATTACCGCGAT
CTATTTATTAATGGTGTATTTCTATTATCTGTATCATAAGCGCAACCCACTTGGTAAAGAGCTTGCCGCGTTAGCAGAAA
TGATGGGCAAAAAATAG

Upstream 100 bases:

>100_bases
TGGGCTATTTTTTCTTATTAGCGCTGATCAGACACCGCCTGATAACTGGGAGCGTTATCATGAATTTACATTATCCGTCG
TTACCGATGATAGATAGCCC

Downstream 100 bases:

>100_bases
CAGATAGTGCAAATGCTATTGTGTATTCTATAGCGCCTATTCTCCCTTATTATTATTGTAACGTTATCTATTATGTTTAT
AAAATCCTTTAGGAGTGCGT

Product: MFS drug efflux transporter (RmrB)

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Facilitator Superfamily Protein; Transport Protein Transmembrane; Facilitator Superfamily Transporter; MFS Drug Efflux Transporter RmrB; Transporter Facilitator Family; Multidrug Resistance Protein B; Transmembrane Efflux Pump Protein; Tat Pathway Signal Sequence Domain Protein; MFS Drug Efflux Transporter; MFS Permease; LOW QUALITY PROTEIN MFS Drug Efflux Transporter; Efflux Protein; Facilitator Superfamily Transporter Protein; MFS Family Transporter; HlyD Family Protein; Facilitator Family Transporter; Facilitator Superfamily Permease

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MSTDYQFKPHEQPFMLGSPATPDHPTYRKVFYLLIGIFIGITASFQNGLLVANLSQIQGEMGLTPVEGGWISVAYNMTNA
CITVLLYKIRQQFGMSLFSKITLFFLLSATSMQWLVSSHLLSSTTGISIDPYYLELIARGFSGVVASAMTVLSIFYCLQG
MPAARRISGLILGFGLVQFGVPLSRIISPYLAADGQLEGLFLFQVGLALICFGLINLLELPRGNMERVFEKLDIVSFVFF
ATGLAALAVFLVQGRILWWTTPWLSYPLIISVVTISIALWIETHRKNPMLQVRWMRSRTIIAFMITGAVMRILLSEQSVG
AAGLLANLGYGNDQLIVFYAIILAASALALVLSIFTTNAMDLRRPVIFAVALIAIGAWIDTGVSLNSTPVMFYFSQFIIA
FAAVYFMGPMVFEGMFRAIANGPAYIISFSVIFGISQTVGGLAGAAGIQAFTTIRTQMHYADMVSSMTAGNPAQMTQMLQ
GIQRQATVAAYDDLFFLMAVSATITAIYLLMVYFYYLYHKRNPLGKELAALAEMMGKK

Sequences:

>Translated_538_residues
MSTDYQFKPHEQPFMLGSPATPDHPTYRKVFYLLIGIFIGITASFQNGLLVANLSQIQGEMGLTPVEGGWISVAYNMTNA
CITVLLYKIRQQFGMSLFSKITLFFLLSATSMQWLVSSHLLSSTTGISIDPYYLELIARGFSGVVASAMTVLSIFYCLQG
MPAARRISGLILGFGLVQFGVPLSRIISPYLAADGQLEGLFLFQVGLALICFGLINLLELPRGNMERVFEKLDIVSFVFF
ATGLAALAVFLVQGRILWWTTPWLSYPLIISVVTISIALWIETHRKNPMLQVRWMRSRTIIAFMITGAVMRILLSEQSVG
AAGLLANLGYGNDQLIVFYAIILAASALALVLSIFTTNAMDLRRPVIFAVALIAIGAWIDTGVSLNSTPVMFYFSQFIIA
FAAVYFMGPMVFEGMFRAIANGPAYIISFSVIFGISQTVGGLAGAAGIQAFTTIRTQMHYADMVSSMTAGNPAQMTQMLQ
GIQRQATVAAYDDLFFLMAVSATITAIYLLMVYFYYLYHKRNPLGKELAALAEMMGKK
>Mature_537_residues
STDYQFKPHEQPFMLGSPATPDHPTYRKVFYLLIGIFIGITASFQNGLLVANLSQIQGEMGLTPVEGGWISVAYNMTNAC
ITVLLYKIRQQFGMSLFSKITLFFLLSATSMQWLVSSHLLSSTTGISIDPYYLELIARGFSGVVASAMTVLSIFYCLQGM
PAARRISGLILGFGLVQFGVPLSRIISPYLAADGQLEGLFLFQVGLALICFGLINLLELPRGNMERVFEKLDIVSFVFFA
TGLAALAVFLVQGRILWWTTPWLSYPLIISVVTISIALWIETHRKNPMLQVRWMRSRTIIAFMITGAVMRILLSEQSVGA
AGLLANLGYGNDQLIVFYAIILAASALALVLSIFTTNAMDLRRPVIFAVALIAIGAWIDTGVSLNSTPVMFYFSQFIIAF
AAVYFMGPMVFEGMFRAIANGPAYIISFSVIFGISQTVGGLAGAAGIQAFTTIRTQMHYADMVSSMTAGNPAQMTQMLQG
IQRQATVAAYDDLFFLMAVSATITAIYLLMVYFYYLYHKRNPLGKELAALAEMMGKK

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 59132; Mature: 59001

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDYQFKPHEQPFMLGSPATPDHPTYRKVFYLLIGIFIGITASFQNGLLVANLSQIQGE
CCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCC
MGLTPVEGGWISVAYNMTNACITVLLYKIRQQFGMSLFSKITLFFLLSATSMQWLVSSHL
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSTTGISIDPYYLELIARGFSGVVASAMTVLSIFYCLQGMPAARRISGLILGFGLVQFG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
VPLSRIISPYLAADGQLEGLFLFQVGLALICFGLINLLELPRGNMERVFEKLDIVSFVFF
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ATGLAALAVFLVQGRILWWTTPWLSYPLIISVVTISIALWIETHRKNPMLQVRWMRSRTI
HHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHH
IAFMITGAVMRILLSEQSVGAAGLLANLGYGNDQLIVFYAIILAASALALVLSIFTTNAM
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLRRPVIFAVALIAIGAWIDTGVSLNSTPVMFYFSQFIIAFAAVYFMGPMVFEGMFRAIA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NGPAYIISFSVIFGISQTVGGLAGAAGIQAFTTIRTQMHYADMVSSMTAGNPAQMTQMLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GIQRQATVAAYDDLFFLMAVSATITAIYLLMVYFYYLYHKRNPLGKELAALAEMMGKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
STDYQFKPHEQPFMLGSPATPDHPTYRKVFYLLIGIFIGITASFQNGLLVANLSQIQGE
CCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCC
MGLTPVEGGWISVAYNMTNACITVLLYKIRQQFGMSLFSKITLFFLLSATSMQWLVSSHL
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSTTGISIDPYYLELIARGFSGVVASAMTVLSIFYCLQGMPAARRISGLILGFGLVQFG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
VPLSRIISPYLAADGQLEGLFLFQVGLALICFGLINLLELPRGNMERVFEKLDIVSFVFF
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ATGLAALAVFLVQGRILWWTTPWLSYPLIISVVTISIALWIETHRKNPMLQVRWMRSRTI
HHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHH
IAFMITGAVMRILLSEQSVGAAGLLANLGYGNDQLIVFYAIILAASALALVLSIFTTNAM
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLRRPVIFAVALIAIGAWIDTGVSLNSTPVMFYFSQFIIAFAAVYFMGPMVFEGMFRAIA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NGPAYIISFSVIFGISQTVGGLAGAAGIQAFTTIRTQMHYADMVSSMTAGNPAQMTQMLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GIQRQATVAAYDDLFFLMAVSATITAIYLLMVYFYYLYHKRNPLGKELAALAEMMGKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA