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The map label for this gene is ureC

Identifier: 93005710

GI number: 93005710

Start: 1044046

End: 1045749

Strand: Direct

Name: ureC

Synonym: Pcryo_0882

Alternate gene names: 93005710

Gene position: 1044046-1045749 (Clockwise)

Preceding gene: 93005709

Following gene: 93005711

Centisome position: 34.12

GC content: 48.3

Gene sequence:

>1704_bases
ATGAAAATATCTCGCGACGCCTATGCCAATATGTATGGTCCGACCGTTGGCGATCGCATCCGTTTGGGTGATACCGAGCT
TTGGATCGAGATTGAAAAGGACCATACCCATTATGGTGAAGAGGTAGTATTCGGTGGCGGTAAAGTGATTCGTGATGGTA
TGGGACAAAGCCAATTGTGCTCAGACTCAGTGATGGATACTGTGATTACCAACGTGATTATTATTGATTGGTGGGGCATC
GTAAAAGCCGATGTTGGCTTAAAAGACGGGCGCATTGTCGCTATTGGTAAAGCCGGCAACCCTGATACGCAGCCGGATGT
TGATATTATCATTGGCGCAGGTACTGAGATTATCGCTGGTGAAAACCAAATATTGACCGCAGGCGCGGTAGATACTCACG
TTCACTATATCTGCCCGCAGCAAGTAGATGAGGCGTTAATGAGCGGTTTAACCACGATGATTGGTGGCGGTACTGGACCT
GCAACTGGCTCAGTCGCTACCACCAACACGCCTGGACCGTGGCACATTGGCAAAATGATGCAAGCCGTGGATGACCTGCC
TATTAACATCGGATTTTTGGGTAAAGGCAGTGCCAGTACGCCTGCAGCACTTGAAGAGCAAGTCAAAGCTGGCGTTATGA
GTTTAAAAGTTCATGAAGATTGGGCGGCAACGCCAGCAACGATTGGTAATGCGCTTGATGTTGCTGACCGTTACGATATT
CAGGTAGCGCTACATGCTGATAGTTTAAATGAGTCAGGCTTTGTTAAAGATACGCTAGAGGCCTTTAAAGATCGCTGTAT
CCATTCGTATCATACTGAAGGTGCGGGTGGTGGTCATGCGCCAGATATTATTGTCGCTTGTGGTCAGCCAAATGTTTTAC
CGTCATCGACCAATCCAACACGCCCGTACACCATCAACACTGTTGACGAGCATCTAGACATGCTGATGGAGTGTCATCAC
TTAGACCCAAATATTCCTGAAGATGTGGCCTTTGCTGATTCGCGTATCCGCCGTGAGACCATTGCTGCAGAAGATATTTT
GCATGATCTTGGTGCCATTTCAATGATTTCATCGGACTCTCAAGCCATGGGCCGTATTGGTGAAGTGGTCTGCCGTACGT
GGCAAACCGCGCACAAAATGCGCCTGCAACGTGGTCTGCTACCAGAAGATCAAGAGCGCGGTACTGATAACTTCCGAGTG
AAACGTTATATTGCCAAATATACTATCAACCCTGCCATCACCCATGGTGTATCACATGAAGTGGGCTCGGTAGAGATTGG
CAAAATGGCAGACTTGGTACTATGGCGTCCTAAGTTTTTTGGTGTTAAGCCCTCCATTATCTTAAAAGGCGGCATGATTG
CTGGTGCCGCAATGGGTGATCCTAACGCCGCAATTTCGACCCCGCAGCCAGTGCATTACCGCCGTATGTTTGGCGCGCTA
GGACGTGCAGTTTCTGCTACTCGCGTTACCTTTGTTAGCCAAGCTGCGATGGACACGGGACTTGAAGAAAAACTGGGGCT
AAGAAGCCGATTGGTCGCTTGTAAAAACGTTCGTAGCATGCGCAAAAAAGACATGAAGCTGAACGATTACTGCCCGAACA
TTACGGTAGATCCAGAAACTTATGAAGTTCGTGTAGACGGTGTGCTTTTAACGTGTGAGCCGCTCTCTGAATTACCATTG
GCGCAGCTTTATCATCTGTTCTAG

Upstream 100 bases:

>100_bases
AGGTGTCGTTGCTGCCTTATGCCGGATTGCGCCGCATCTTTGGCTTTAGAGGTGAGGTGATGGGTGCGCTAGATGACAAT
TCAGATTCAGGAGAAACACG

Downstream 100 bases:

>100_bases
ACCAATTGTTTTAAATCGTTTGTAAGGATAATAATATGCTTGAATTAATAAAAAGAATGGACGGCAATACTTCGGTCGAC
ATTTATGACACCTTGACCTT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha 1

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MKISRDAYANMYGPTVGDRIRLGDTELWIEIEKDHTHYGEEVVFGGGKVIRDGMGQSQLCSDSVMDTVITNVIIIDWWGI
VKADVGLKDGRIVAIGKAGNPDTQPDVDIIIGAGTEIIAGENQILTAGAVDTHVHYICPQQVDEALMSGLTTMIGGGTGP
ATGSVATTNTPGPWHIGKMMQAVDDLPINIGFLGKGSASTPAALEEQVKAGVMSLKVHEDWAATPATIGNALDVADRYDI
QVALHADSLNESGFVKDTLEAFKDRCIHSYHTEGAGGGHAPDIIVACGQPNVLPSSTNPTRPYTINTVDEHLDMLMECHH
LDPNIPEDVAFADSRIRRETIAAEDILHDLGAISMISSDSQAMGRIGEVVCRTWQTAHKMRLQRGLLPEDQERGTDNFRV
KRYIAKYTINPAITHGVSHEVGSVEIGKMADLVLWRPKFFGVKPSIILKGGMIAGAAMGDPNAAISTPQPVHYRRMFGAL
GRAVSATRVTFVSQAAMDTGLEEKLGLRSRLVACKNVRSMRKKDMKLNDYCPNITVDPETYEVRVDGVLLTCEPLSELPL
AQLYHLF

Sequences:

>Translated_567_residues
MKISRDAYANMYGPTVGDRIRLGDTELWIEIEKDHTHYGEEVVFGGGKVIRDGMGQSQLCSDSVMDTVITNVIIIDWWGI
VKADVGLKDGRIVAIGKAGNPDTQPDVDIIIGAGTEIIAGENQILTAGAVDTHVHYICPQQVDEALMSGLTTMIGGGTGP
ATGSVATTNTPGPWHIGKMMQAVDDLPINIGFLGKGSASTPAALEEQVKAGVMSLKVHEDWAATPATIGNALDVADRYDI
QVALHADSLNESGFVKDTLEAFKDRCIHSYHTEGAGGGHAPDIIVACGQPNVLPSSTNPTRPYTINTVDEHLDMLMECHH
LDPNIPEDVAFADSRIRRETIAAEDILHDLGAISMISSDSQAMGRIGEVVCRTWQTAHKMRLQRGLLPEDQERGTDNFRV
KRYIAKYTINPAITHGVSHEVGSVEIGKMADLVLWRPKFFGVKPSIILKGGMIAGAAMGDPNAAISTPQPVHYRRMFGAL
GRAVSATRVTFVSQAAMDTGLEEKLGLRSRLVACKNVRSMRKKDMKLNDYCPNITVDPETYEVRVDGVLLTCEPLSELPL
AQLYHLF
>Mature_567_residues
MKISRDAYANMYGPTVGDRIRLGDTELWIEIEKDHTHYGEEVVFGGGKVIRDGMGQSQLCSDSVMDTVITNVIIIDWWGI
VKADVGLKDGRIVAIGKAGNPDTQPDVDIIIGAGTEIIAGENQILTAGAVDTHVHYICPQQVDEALMSGLTTMIGGGTGP
ATGSVATTNTPGPWHIGKMMQAVDDLPINIGFLGKGSASTPAALEEQVKAGVMSLKVHEDWAATPATIGNALDVADRYDI
QVALHADSLNESGFVKDTLEAFKDRCIHSYHTEGAGGGHAPDIIVACGQPNVLPSSTNPTRPYTINTVDEHLDMLMECHH
LDPNIPEDVAFADSRIRRETIAAEDILHDLGAISMISSDSQAMGRIGEVVCRTWQTAHKMRLQRGLLPEDQERGTDNFRV
KRYIAKYTINPAITHGVSHEVGSVEIGKMADLVLWRPKFFGVKPSIILKGGMIAGAAMGDPNAAISTPQPVHYRRMFGAL
GRAVSATRVTFVSQAAMDTGLEEKLGLRSRLVACKNVRSMRKKDMKLNDYCPNITVDPETYEVRVDGVLLTCEPLSELPL
AQLYHLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE11_PSYCK (Q1QCE0)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_580147.1
- ProteinModelPortal:   Q1QCE0
- SMR:   Q1QCE0
- STRING:   Q1QCE0
- GeneID:   4034021
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_0882
- NMPDR:   fig|335284.3.peg.243
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   VAHGIDH
- ProtClustDB:   PRK13207
- BioCyc:   PCRY335284:PCRYO_0882-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61412; Mature: 61412

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 319-319 BINDING 218-218

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISRDAYANMYGPTVGDRIRLGDTELWIEIEKDHTHYGEEVVFGGGKVIRDGMGQSQLC
CCCCCCHHHHHCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEECCCHHHHCCCCCHHHH
SDSVMDTVITNVIIIDWWGIVKADVGLKDGRIVAIGKAGNPDTQPDVDIIIGAGTEIIAG
HHHHHHHHHHHEEEEEECCCEEECCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEEEEC
ENQILTAGAVDTHVHYICPQQVDEALMSGLTTMIGGGTGPATGSVATTNTPGPWHIGKMM
CCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHH
QAVDDLPINIGFLGKGSASTPAALEEQVKAGVMSLKVHEDWAATPATIGNALDVADRYDI
HHHHCCCEEEEEECCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCHHCCCHHCCCCCCEE
QVALHADSLNESGFVKDTLEAFKDRCIHSYHTEGAGGGHAPDIIVACGQPNVLPSSTNPT
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
RPYTINTVDEHLDMLMECHHLDPNIPEDVAFADSRIRRETIAAEDILHDLGAISMISSDS
CCEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCH
QAMGRIGEVVCRTWQTAHKMRLQRGLLPEDQERGTDNFRVKRYIAKYTINPAITHGVSHE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHEECCHHHHCCCCCC
VGSVEIGKMADLVLWRPKFFGVKPSIILKGGMIAGAAMGDPNAAISTPQPVHYRRMFGAL
CCCEECCCHHHEEEECCHHCCCCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
GRAVSATRVTFVSQAAMDTGLEEKLGLRSRLVACKNVRSMRKKDMKLNDYCPNITVDPET
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEECCCE
YEVRVDGVLLTCEPLSELPLAQLYHLF
EEEEEEEEEEEECCHHHCCHHHHHHCC
>Mature Secondary Structure
MKISRDAYANMYGPTVGDRIRLGDTELWIEIEKDHTHYGEEVVFGGGKVIRDGMGQSQLC
CCCCCCHHHHHCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEECCCHHHHCCCCCHHHH
SDSVMDTVITNVIIIDWWGIVKADVGLKDGRIVAIGKAGNPDTQPDVDIIIGAGTEIIAG
HHHHHHHHHHHEEEEEECCCEEECCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEEEEC
ENQILTAGAVDTHVHYICPQQVDEALMSGLTTMIGGGTGPATGSVATTNTPGPWHIGKMM
CCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHH
QAVDDLPINIGFLGKGSASTPAALEEQVKAGVMSLKVHEDWAATPATIGNALDVADRYDI
HHHHCCCEEEEEECCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCHHCCCHHCCCCCCEE
QVALHADSLNESGFVKDTLEAFKDRCIHSYHTEGAGGGHAPDIIVACGQPNVLPSSTNPT
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
RPYTINTVDEHLDMLMECHHLDPNIPEDVAFADSRIRRETIAAEDILHDLGAISMISSDS
CCEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCH
QAMGRIGEVVCRTWQTAHKMRLQRGLLPEDQERGTDNFRVKRYIAKYTINPAITHGVSHE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHEECCHHHHCCCCCC
VGSVEIGKMADLVLWRPKFFGVKPSIILKGGMIAGAAMGDPNAAISTPQPVHYRRMFGAL
CCCEECCCHHHEEEECCHHCCCCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
GRAVSATRVTFVSQAAMDTGLEEKLGLRSRLVACKNVRSMRKKDMKLNDYCPNITVDPET
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEECCCE
YEVRVDGVLLTCEPLSELPLAQLYHLF
EEEEEEEEEEEECCHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA