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The map label for this gene is mmgC [H]

Identifier: 93005645

GI number: 93005645

Start: 962420

End: 963604

Strand: Direct

Name: mmgC [H]

Synonym: Pcryo_0815

Alternate gene names: 93005645

Gene position: 962420-963604 (Clockwise)

Preceding gene: 93005640

Following gene: 93005646

Centisome position: 31.45

GC content: 47.59

Gene sequence:

>1185_bases
ATGGCAACTTCTAGCAGCCCACGTTTTGATTGGGAAGATCCATTTTTATTACGTGACCAGCTTACAGATGAAGAGCGCAT
GGTAACGGACAGTGCGCGTCAGTTTTTTCAAAAAGAGCTGATGCCGGGTATCATTCAGGCCAATCGTAATGAACATTTTG
ACCGCGATATCATGCGTCAGATGGGCGAGATGGGTCTTCTTGGTGTGACGATCGACGGTTATGGTTGTGCTGGCATGTCA
AGCGTGGCTTATGGTTTGATTGCGAAAGAAGTGGAAGCGGTGGATTCGGGCTATCGTTCAGCGATGAGCGTGCAGTCAAG
CTTGGTCATGCATCCGATACATGCCTATGGTACAGAAGAGCAGAAAGAAAAATATCTGCCAAAACTGGCAACTGGGGAAT
ATGTCGGCTGCTTTGGTCTTACAGAGCCGGATTCGGGTTCAGATCCTTCATCAATGTCAACGCGCGCGCGCGCAGTGGCA
GGCGGTTATGAGCTGACTGGTAATAAAATGTGGATTACCAATAGCCCGATTTCTGATGTATTTGTCGTTTGGGCAAAAGA
TGATGCCGGTGACATTTGTGGTTTTATCTTAGATAAAGGTATGAAAGGGCTGTCCGCACCGAAAATCGAAGGCAAGTTCT
CATTGCGTGCGTCTGTCACGGGTGAGATTGTCATGGACAAAGTGTTTGTCCCTGAAGCCAATGCTTTCCCAGATATTCGT
GGTCTAAAAGGTCCGTTTGGTTGCCTAAATAAAGCCCGTTATGGTATCGCTTGGGGTTCAATGGGTGCGGCTGAATTCTG
CTGGAAAGCGGCTCGTCAGTACACCCTTGACCGTAAGCAGTTTGGTCGTCCGCTAGCCGCGACACAGTTGGTACAGCTAA
AACTTGCCAATATGCAAACGGAAATCACACTAGGTCTACAAGCAGCATTGCGTGTTGGCCGTTTGATGGATGAGGACAAT
GCGGCGCCTGAAATGATTTCACTGATTAAGCGTAATAACTGCGGCAAAGCGCTAGAGATTGCCCGTATTGCCCGTGATAT
GCATGGCGGCAATGGTATCTCTGATGAGTTTCATATTATTCGTCATGTGATGAATTTAGAAGCGGTCAATACTTATGAAG
GTACCCATGATATTCATGCGCTCATCTTAGGTCGCGCGCAGACTGGGATTCAGGCATTTTATTAA

Upstream 100 bases:

>100_bases
GTTTCGCATAGCGGAATTTTGAAGTCAATAGTAAATTTAGCCAAAGCATCATATTCACCATTAATCGTCGGTCAGGATGA
CTGACAACAAGGAGCACCAC

Downstream 100 bases:

>100_bases
GCGTTATTAGCTAATAAGTATTAGCTAATTTCCCGACCATTAACGTACGTTACTGTTGTGCTTCTTACGAAGCACCTGAT
AAGCAGTAGCGTGCGTTTTT

Product: glutaryl-CoA dehydrogenase

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MATSSSPRFDWEDPFLLRDQLTDEERMVTDSARQFFQKELMPGIIQANRNEHFDRDIMRQMGEMGLLGVTIDGYGCAGMS
SVAYGLIAKEVEAVDSGYRSAMSVQSSLVMHPIHAYGTEEQKEKYLPKLATGEYVGCFGLTEPDSGSDPSSMSTRARAVA
GGYELTGNKMWITNSPISDVFVVWAKDDAGDICGFILDKGMKGLSAPKIEGKFSLRASVTGEIVMDKVFVPEANAFPDIR
GLKGPFGCLNKARYGIAWGSMGAAEFCWKAARQYTLDRKQFGRPLAATQLVQLKLANMQTEITLGLQAALRVGRLMDEDN
AAPEMISLIKRNNCGKALEIARIARDMHGGNGISDEFHIIRHVMNLEAVNTYEGTHDIHALILGRAQTGIQAFY

Sequences:

>Translated_394_residues
MATSSSPRFDWEDPFLLRDQLTDEERMVTDSARQFFQKELMPGIIQANRNEHFDRDIMRQMGEMGLLGVTIDGYGCAGMS
SVAYGLIAKEVEAVDSGYRSAMSVQSSLVMHPIHAYGTEEQKEKYLPKLATGEYVGCFGLTEPDSGSDPSSMSTRARAVA
GGYELTGNKMWITNSPISDVFVVWAKDDAGDICGFILDKGMKGLSAPKIEGKFSLRASVTGEIVMDKVFVPEANAFPDIR
GLKGPFGCLNKARYGIAWGSMGAAEFCWKAARQYTLDRKQFGRPLAATQLVQLKLANMQTEITLGLQAALRVGRLMDEDN
AAPEMISLIKRNNCGKALEIARIARDMHGGNGISDEFHIIRHVMNLEAVNTYEGTHDIHALILGRAQTGIQAFY
>Mature_393_residues
ATSSSPRFDWEDPFLLRDQLTDEERMVTDSARQFFQKELMPGIIQANRNEHFDRDIMRQMGEMGLLGVTIDGYGCAGMSS
VAYGLIAKEVEAVDSGYRSAMSVQSSLVMHPIHAYGTEEQKEKYLPKLATGEYVGCFGLTEPDSGSDPSSMSTRARAVAG
GYELTGNKMWITNSPISDVFVVWAKDDAGDICGFILDKGMKGLSAPKIEGKFSLRASVTGEIVMDKVFVPEANAFPDIRG
LKGPFGCLNKARYGIAWGSMGAAEFCWKAARQYTLDRKQFGRPLAATQLVQLKLANMQTEITLGLQAALRVGRLMDEDNA
APEMISLIKRNNCGKALEIARIARDMHGGNGISDEFHIIRHVMNLEAVNTYEGTHDIHALILGRAQTGIQAFY

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=395, Percent_Identity=69.3670886075949, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI7669494, Length=375, Percent_Identity=68, Blast_Score=541, Evalue=1e-154,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=30.3191489361702, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=30.958904109589, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=29.8387096774194, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI226958414, Length=345, Percent_Identity=30.4347826086957, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=29.4117647058824, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=28.90625, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=28.90625, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=27.4666666666667, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=27.4666666666667, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=27.0557029177719, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI21361497, Length=350, Percent_Identity=28, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=24.331550802139, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=25.7894736842105, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081702, Length=373, Percent_Identity=24.6648793565684, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534353, Length=387, Percent_Identity=62.5322997416021, Blast_Score=510, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=31.3984168865435, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17508101, Length=391, Percent_Identity=29.923273657289, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=28.2666666666667, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=28.5333333333333, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71985184, Length=386, Percent_Identity=28.2383419689119, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=28.2191780821918, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=246, Percent_Identity=35.3658536585366, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=368, Percent_Identity=26.9021739130435, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=296, Percent_Identity=30.0675675675676, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=30.4029304029304, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=223, Percent_Identity=32.7354260089686, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=406, Percent_Identity=22.6600985221675, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551932, Length=278, Percent_Identity=23.7410071942446, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920834, Length=396, Percent_Identity=61.6161616161616, Blast_Score=511, Evalue=1e-145,
Organism=Drosophila melanogaster, GI24666513, Length=368, Percent_Identity=32.0652173913043, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=29.7297297297297, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=31.283422459893, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=29.3010752688172, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=30.1587301587302, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281363737, Length=401, Percent_Identity=29.6758104738155, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43317; Mature: 43186

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSSSPRFDWEDPFLLRDQLTDEERMVTDSARQFFQKELMPGIIQANRNEHFDRDIMRQ
CCCCCCCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHH
MGEMGLLGVTIDGYGCAGMSSVAYGLIAKEVEAVDSGYRSAMSVQSSLVMHPIHAYGTEE
HHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHH
QKEKYLPKLATGEYVGCFGLTEPDSGSDPSSMSTRARAVAGGYELTGNKMWITNSPISDV
HHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEECCCEEEEECCCCCCE
FVVWAKDDAGDICGFILDKGMKGLSAPKIEGKFSLRASVTGEIVMDKVFVPEANAFPDIR
EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHEEEEECCCCCCCCCCC
GLKGPFGCLNKARYGIAWGSMGAAEFCWKAARQYTLDRKQFGRPLAATQLVQLKLANMQT
CCCCCHHHHHHHHCCEEECCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCC
EITLGLQAALRVGRLMDEDNAAPEMISLIKRNNCGKALEIARIARDMHGGNGISDEFHII
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
RHVMNLEAVNTYEGTHDIHALILGRAQTGIQAFY
HHHHHHHHEECCCCCHHEEHHEEECHHCCHHHCC
>Mature Secondary Structure 
ATSSSPRFDWEDPFLLRDQLTDEERMVTDSARQFFQKELMPGIIQANRNEHFDRDIMRQ
CCCCCCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHH
MGEMGLLGVTIDGYGCAGMSSVAYGLIAKEVEAVDSGYRSAMSVQSSLVMHPIHAYGTEE
HHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHH
QKEKYLPKLATGEYVGCFGLTEPDSGSDPSSMSTRARAVAGGYELTGNKMWITNSPISDV
HHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEECCCEEEEECCCCCCE
FVVWAKDDAGDICGFILDKGMKGLSAPKIEGKFSLRASVTGEIVMDKVFVPEANAFPDIR
EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHEEEEECCCCCCCCCCC
GLKGPFGCLNKARYGIAWGSMGAAEFCWKAARQYTLDRKQFGRPLAATQLVQLKLANMQT
CCCCCHHHHHHHHCCEEECCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCC
EITLGLQAALRVGRLMDEDNAAPEMISLIKRNNCGKALEIARIARDMHGGNGISDEFHII
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
RHVMNLEAVNTYEGTHDIHALILGRAQTGIQAFY
HHHHHHHHEECCCCCHHEEHHEEECHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]