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The map label for this gene is rhtC [H]

Identifier: 93004840

GI number: 93004840

Start: 10559

End: 11296

Strand: Reverse

Name: rhtC [H]

Synonym: Pcryo_0009

Alternate gene names: 93004840

Gene position: 11296-10559 (Counterclockwise)

Preceding gene: 93004842

Following gene: 93004839

Centisome position: 0.37

GC content: 44.99

Gene sequence:

>738_bases
ATGGAATTTTGGCACGGTTTTTTGCTTATCACCAGCGTCCATCTACTCGCTGCCGCCTCTCCAGGTCCTGATTTTGTTTT
GGTCTCGCAGCAAACTTTGGCAAAAGGTCGACGCACAGGTTTGATTTGTAGCCTTGGTATTACCTTGGGTCTTGCCGTAC
ACATTATTTATTCGGTGCTAGGACTGGCAACGCTGATTGCCCACTCGCAGCCATTATTGACCGCTATCAAATGGTTAGGC
GGTAGTTATCTTATTTATCTAGGATGGCAAGGCATTCAAGCCAAAGCTAAAAAGCCAGCTGACTTAGCCCTTTCCGCAGA
ACCAACAGATTCAGGCGCTCACGTTCCACAAGATACGCTTGCCAAGCAAAAGACGCTTATCACTCACACAGCGCTTTCTG
ATAAAGCTATTTCTAATAAAAAACTGTCTACTGATACTGAATCGACCACTGCCATTCTGCGCCGTGGCTTTTTTTGTAAT
GTGTTTAATCCAAAAGCACCAGTATATTTCGTCGCGATATTTACCCTCGTACTCTCACCCGATATACCGCTGTGGCAACT
GGCTATTTATGGCGTATGGATGATGGTCTTGCAGATGGCATGGTTTAGTACCGTGGTGATGTTACTGTCTATTCCTGCCG
TTCATCGTCGCTTTCAGCGTTTTGAACATTGGATCGACCGCGTATTGGGTACAGCGATGATAATATTGGGATTAAATCTT
ATTTTACGTAGTCGATAA

Upstream 100 bases:

>100_bases
TAACGCAAGCACCATATCAGCGGTGATATCAATATCAGTTGACCTCATTTACGCTAATGTGCAACTATTATCCAACTCAA
GACATGACTCAGAGCATTTT

Downstream 100 bases:

>100_bases
GACGCTAGTGACTCATGAAATCTGCTAAAATGGTGCATTATATTCAAACATCAAAGCCCGATACTATGACCAGTAAGCCT
ATGAACCGTCGCCCGACCGC

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MEFWHGFLLITSVHLLAAASPGPDFVLVSQQTLAKGRRTGLICSLGITLGLAVHIIYSVLGLATLIAHSQPLLTAIKWLG
GSYLIYLGWQGIQAKAKKPADLALSAEPTDSGAHVPQDTLAKQKTLITHTALSDKAISNKKLSTDTESTTAILRRGFFCN
VFNPKAPVYFVAIFTLVLSPDIPLWQLAIYGVWMMVLQMAWFSTVVMLLSIPAVHRRFQRFEHWIDRVLGTAMIILGLNL
ILRSR

Sequences:

>Translated_245_residues
MEFWHGFLLITSVHLLAAASPGPDFVLVSQQTLAKGRRTGLICSLGITLGLAVHIIYSVLGLATLIAHSQPLLTAIKWLG
GSYLIYLGWQGIQAKAKKPADLALSAEPTDSGAHVPQDTLAKQKTLITHTALSDKAISNKKLSTDTESTTAILRRGFFCN
VFNPKAPVYFVAIFTLVLSPDIPLWQLAIYGVWMMVLQMAWFSTVVMLLSIPAVHRRFQRFEHWIDRVLGTAMIILGLNL
ILRSR
>Mature_245_residues
MEFWHGFLLITSVHLLAAASPGPDFVLVSQQTLAKGRRTGLICSLGITLGLAVHIIYSVLGLATLIAHSQPLLTAIKWLG
GSYLIYLGWQGIQAKAKKPADLALSAEPTDSGAHVPQDTLAKQKTLITHTALSDKAISNKKLSTDTESTTAILRRGFFCN
VFNPKAPVYFVAIFTLVLSPDIPLWQLAIYGVWMMVLQMAWFSTVVMLLSIPAVHRRFQRFEHWIDRVLGTAMIILGLNL
ILRSR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=238, Percent_Identity=30.672268907563, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786522, Length=241, Percent_Identity=23.6514522821577, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 27017; Mature: 27017

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFWHGFLLITSVHLLAAASPGPDFVLVSQQTLAKGRRTGLICSLGITLGLAVHIIYSVL
CCHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHH
GLATLIAHSQPLLTAIKWLGGSYLIYLGWQGIQAKAKKPADLALSAEPTDSGAHVPQDTL
HHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHH
AKQKTLITHTALSDKAISNKKLSTDTESTTAILRRGFFCNVFNPKAPVYFVAIFTLVLSP
HHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCC
DIPLWQLAIYGVWMMVLQMAWFSTVVMLLSIPAVHRRFQRFEHWIDRVLGTAMIILGLNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRSR
HHCCC
>Mature Secondary Structure
MEFWHGFLLITSVHLLAAASPGPDFVLVSQQTLAKGRRTGLICSLGITLGLAVHIIYSVL
CCHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHH
GLATLIAHSQPLLTAIKWLGGSYLIYLGWQGIQAKAKKPADLALSAEPTDSGAHVPQDTL
HHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHH
AKQKTLITHTALSDKAISNKKLSTDTESTTAILRRGFFCNVFNPKAPVYFVAIFTLVLSP
HHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCC
DIPLWQLAIYGVWMMVLQMAWFSTVVMLLSIPAVHRRFQRFEHWIDRVLGTAMIILGLNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRSR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]