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The map label for this gene is mltA [H]

Identifier: 92115392

GI number: 92115392

Start: 3653368

End: 3654492

Strand: Direct

Name: mltA [H]

Synonym: Csal_3277

Alternate gene names: 92115392

Gene position: 3653368-3654492 (Clockwise)

Preceding gene: 92115391

Following gene: 92115393

Centisome position: 98.83

GC content: 68.62

Gene sequence:

>1125_bases
TTGCTCACGTTCCTGTCGCCACGTATCGCCGACGCCTTCCAGCGGGTGCGCCGGCTCGGTCATGCGCTGTGGTTGCTGCC
TGTCTCATTGCTGGCCGCCTGCAGTACGCAAGCGCCGTCGCCCGGCCCCGGCGCACCGCCTCCCGCGACCGCAGAACACA
TGCGTCCCGCCGCCTGGCAGTCGCTGCCCGGCTGGTCGGACGATCACGTCATCGCCGCCTGGAGCGCCTTTCTCGCCAGC
TGCGAGCGTCTGACCGGGAAAGCGCAATGGCGCGATGTCTGCCACGACGCGGTGACCGTCGACCCTCTCGATGAAGTCGC
CATCACGCGCTTTTTCGAGACACGTTTCCAGCCTTACCGCCTGGTCAACGACGACGGCTCCACCACGGGCACGATCACCG
GCTACTACGAACCCATCCTGAACGGCTCGCGTACACGGCACGGGCCCTACCAGACCCCGCTCTACCGCTTTCCCGACGCC
TGGCAGGCGGCACCGCAACGCGTGCGTGCCTCGCAGCGGGAACTGTTGCAAAGCGGAGCCCTGCGCGGCCAGGAGCTGGT
CTGGGTCGACGATCCCGTCGAGGCGGCGTTCCTGCAGATCCAGGGGTCGGGGCGTGTCCGTCTGGACGACGGCAGCACCA
TGCGCGTGGCCTTTGCGGGCACCAACAACCAACCCTTTCGCTCCTTCAACCGTGCCCTGATCGAGCGCGGCGAAATCGAC
GCCTCCCAGGCGACGCTGCCCGGCGTGCGCGCCTGGGCCAGGCGCCATCCCGAGCGGGTCGAGGAGATGCTCACCGTCAA
TCCGCGCATGGTCTTCTTTCGAGAACTGGGCAGCGACCATGGCGCGCACCAAGGCCCCATCGGCGCCCTCGGTGTGCCGC
TGACGTCCGAACGCAGCCTGGCGGTGGACCCCTCGCAGGTACCGCTGGGCGCACCGGTATTCCTGTCGACGACGGAGCCT
GCCTCCGCGCAGCCCCTGCAGCGCCTCATGGTGGCCCAGGACACCGGCAGCGCCATCCAGGGCACGGTGCGCGCGGATTT
CTACTGGGGGCACGGCGACACCGCCGGCGAACGCGCCGGACGCATGAAGCAACCCGGTCAGATGTGGGTGCTGATGCCCA
AATGA

Upstream 100 bases:

>100_bases
AGCGCACCACGCCACTGGCACGAAGCGCCGCGGCAAGGCATCATCGCTGACGACACCCGGCGGGTGTTTGCCATCGGATT
CGAATGTCGAGGTGCCTTGC

Downstream 100 bases:

>100_bases
CGACACGTCCCCGACCGGGCGTCGGGAAAAAGCGCCAGGGAGGATGACCCATGCACGATCAACCCCAGGCGACGGCGCCA
CTGGCCGTCGTGACCGGCGC

Product: MltA

Products: Muramic Acid Residue [C]

Alternate protein names: Mlt38; Murein hydrolase A [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MLTFLSPRIADAFQRVRRLGHALWLLPVSLLAACSTQAPSPGPGAPPPATAEHMRPAAWQSLPGWSDDHVIAAWSAFLAS
CERLTGKAQWRDVCHDAVTVDPLDEVAITRFFETRFQPYRLVNDDGSTTGTITGYYEPILNGSRTRHGPYQTPLYRFPDA
WQAAPQRVRASQRELLQSGALRGQELVWVDDPVEAAFLQIQGSGRVRLDDGSTMRVAFAGTNNQPFRSFNRALIERGEID
ASQATLPGVRAWARRHPERVEEMLTVNPRMVFFRELGSDHGAHQGPIGALGVPLTSERSLAVDPSQVPLGAPVFLSTTEP
ASAQPLQRLMVAQDTGSAIQGTVRADFYWGHGDTAGERAGRMKQPGQMWVLMPK

Sequences:

>Translated_374_residues
MLTFLSPRIADAFQRVRRLGHALWLLPVSLLAACSTQAPSPGPGAPPPATAEHMRPAAWQSLPGWSDDHVIAAWSAFLAS
CERLTGKAQWRDVCHDAVTVDPLDEVAITRFFETRFQPYRLVNDDGSTTGTITGYYEPILNGSRTRHGPYQTPLYRFPDA
WQAAPQRVRASQRELLQSGALRGQELVWVDDPVEAAFLQIQGSGRVRLDDGSTMRVAFAGTNNQPFRSFNRALIERGEID
ASQATLPGVRAWARRHPERVEEMLTVNPRMVFFRELGSDHGAHQGPIGALGVPLTSERSLAVDPSQVPLGAPVFLSTTEP
ASAQPLQRLMVAQDTGSAIQGTVRADFYWGHGDTAGERAGRMKQPGQMWVLMPK
>Mature_374_residues
MLTFLSPRIADAFQRVRRLGHALWLLPVSLLAACSTQAPSPGPGAPPPATAEHMRPAAWQSLPGWSDDHVIAAWSAFLAS
CERLTGKAQWRDVCHDAVTVDPLDEVAITRFFETRFQPYRLVNDDGSTTGTITGYYEPILNGSRTRHGPYQTPLYRFPDA
WQAAPQRVRASQRELLQSGALRGQELVWVDDPVEAAFLQIQGSGRVRLDDGSTMRVAFAGTNNQPFRSFNRALIERGEID
ASQATLPGVRAWARRHPERVEEMLTVNPRMVFFRELGSDHGAHQGPIGALGVPLTSERSLAVDPSQVPLGAPVFLSTTEP
ASAQPLQRLMVAQDTGSAIQGTVRADFYWGHGDTAGERAGRMKQPGQMWVLMPK

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=249, Percent_Identity=34.9397590361446, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 41123; Mature: 41123

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFLSPRIADAFQRVRRLGHALWLLPVSLLAACSTQAPSPGPGAPPPATAEHMRPAAWQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHH
SLPGWSDDHVIAAWSAFLASCERLTGKAQWRDVCHDAVTVDPLDEVAITRFFETRFQPYR
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEE
LVNDDGSTTGTITGYYEPILNGSRTRHGPYQTPLYRFPDAWQAAPQRVRASQRELLQSGA
EECCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
LRGQELVWVDDPVEAAFLQIQGSGRVRLDDGSTMRVAFAGTNNQPFRSFNRALIERGEID
CCCCEEEEECCCCCEEEEEEECCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCC
ASQATLPGVRAWARRHPERVEEMLTVNPRMVFFRELGSDHGAHQGPIGALGVPLTSERSL
CCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCE
AVDPSQVPLGAPVFLSTTEPASAQPLQRLMVAQDTGSAIQGTVRADFYWGHGDTAGERAG
EECCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHCCEEEEEEEECCCCCHHHHCC
RMKQPGQMWVLMPK
CCCCCCCEEEEECC
>Mature Secondary Structure
MLTFLSPRIADAFQRVRRLGHALWLLPVSLLAACSTQAPSPGPGAPPPATAEHMRPAAWQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHH
SLPGWSDDHVIAAWSAFLASCERLTGKAQWRDVCHDAVTVDPLDEVAITRFFETRFQPYR
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEE
LVNDDGSTTGTITGYYEPILNGSRTRHGPYQTPLYRFPDAWQAAPQRVRASQRELLQSGA
EECCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
LRGQELVWVDDPVEAAFLQIQGSGRVRLDDGSTMRVAFAGTNNQPFRSFNRALIERGEID
CCCCEEEEECCCCCEEEEEEECCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCC
ASQATLPGVRAWARRHPERVEEMLTVNPRMVFFRELGSDHGAHQGPIGALGVPLTSERSL
CCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCE
AVDPSQVPLGAPVFLSTTEPASAQPLQRLMVAQDTGSAIQGTVRADFYWGHGDTAGERAG
EECCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHCCEEEEEEEECCCCCHHHHCC
RMKQPGQMWVLMPK
CCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]