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The map label for this gene is phoR [H]

Identifier: 92115369

GI number: 92115369

Start: 3627481

End: 3628800

Strand: Direct

Name: phoR [H]

Synonym: Csal_3254

Alternate gene names: 92115369

Gene position: 3627481-3628800 (Clockwise)

Preceding gene: 92115368

Following gene: 92115378

Centisome position: 98.13

GC content: 66.14

Gene sequence:

>1320_bases
GTGCACTATTGGACCAACGAACTGTGGCGACTGGCGTACCTGGTCGTCGGACTCGGTGCCCTGGGCTGGCTGCTCGGCGA
GCCCGGCTGGGGGCTGGCCGCCGGCCTGGGCCTCTACGTGTATCTGCATCTGCGCCATTTGCGTGCCCTGTACGTCTGGC
TGACCCAGCACCCCCACGAGACACCCCCCGTCGGGGCCGGCGTCTGGGGCGATCTGTTCGACCGCCTCTACAAGTATCAG
AAGACGCAGCGCCAATCCCAGGCACGCCTGCGCGACATCATCCGGCGCGTGCAGGACTCCTGCGAGGCGATGCGCGATGC
CGTGGTCATGCTCGACGGCCATGGCGATCTGGAGTGGTGGAACACCGCCGCCACGCAGATGCTCGGCTTTCAATCGCCCC
ACGACCGCGGCCAGCACATCACCAACTTCCTGCGGGACCCGCGCTTCGTGGCCTACTTCAACGCCCGCGATTACCGCGAA
CCGCTCACCCTGGCATCGCCCTTGCGCGATGACGTGACGCTGCAGTATCAAATCACGTTGTTCGGCGACAACGAGCGCCT
GGTCATGGCCCGCGACATCTCGCGACTGCATCGCCTGGAAGAAATGCGGCGCGACTTCGTCGCCAACGTTTCCCACGAAC
TGCGCACGCCGCTCACCGTGCTCACCGGCTATCTGGAAACCTACCTCGACAACGCCGATCAATTACCGCCCCGCTGGCAA
CGGGGTCTCGGACAGATGCAGGAGCAGTCGCAACGCATGCAGCGACTGGTCGAGGATCTGCTGTTGCTGTCGAAGCTGGA
AACCGACCAGACCCGTGACGATCCAGTACCGCTGGACATGGCCGCGCTGCTGGCGAACATTCGCGACGATGCCGCCGCGC
TCTGCAACGGCAGTCATGACGTGCGCCTGGAAATCGACGACGACCGCCATCTGCTGGGCGCCGATGGCGAGATACGCAGC
GCCGTTTCCAACCTGGTCTTCAACGCCGTGCGATACACGCCGTCGGGCAGCACCGTCACGTTGCGCTGGAAAGCCTGGAA
GGAGGGTGCCGCGGTCGAGGTCGAGGACGACGGCGAAGGGATCGACCCGGTACACCTGCCACGCCTCACCGAGCGTTTCT
ACCGCGTCGACAAGGGGCGCAGCGCCGCCAACGGCGGCACCGGCCTGGGCCTGGCCATCGTCAAGCACGTCCTGCTGCGC
CACGACGCGCACCTCGATATCGACAGCCACCCCGGCCAGGGTGCGCTCTTTCGTTGCGTGTTTCCCGCCGCACGGCTGAA
TGCCGCCCCTGCCGAACGCCGTGCCGTGGGCGGCGACTAG

Upstream 100 bases:

>100_bases
GCACATCCGCCGCCTGCGCAAGGCGCTCGGCGAGGCCCATCAGCATCTCATCCAGACGGTACGCGGCACCGGTTATCGCT
TCTCCGCCAAGGACTAGCGC

Downstream 100 bases:

>100_bases
TCTTGTAGGTGCGGCATCGCCCGCTTCTGGAAAGGCGCTCGGCTCCCTCCGTCACGGTCGGATGGAGAAAAAAGCGGCGG
GAGAAAAAGCGGCGGGAGAA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MHYWTNELWRLAYLVVGLGALGWLLGEPGWGLAAGLGLYVYLHLRHLRALYVWLTQHPHETPPVGAGVWGDLFDRLYKYQ
KTQRQSQARLRDIIRRVQDSCEAMRDAVVMLDGHGDLEWWNTAATQMLGFQSPHDRGQHITNFLRDPRFVAYFNARDYRE
PLTLASPLRDDVTLQYQITLFGDNERLVMARDISRLHRLEEMRRDFVANVSHELRTPLTVLTGYLETYLDNADQLPPRWQ
RGLGQMQEQSQRMQRLVEDLLLLSKLETDQTRDDPVPLDMAALLANIRDDAAALCNGSHDVRLEIDDDRHLLGADGEIRS
AVSNLVFNAVRYTPSGSTVTLRWKAWKEGAAVEVEDDGEGIDPVHLPRLTERFYRVDKGRSAANGGTGLGLAIVKHVLLR
HDAHLDIDSHPGQGALFRCVFPAARLNAAPAERRAVGGD

Sequences:

>Translated_439_residues
MHYWTNELWRLAYLVVGLGALGWLLGEPGWGLAAGLGLYVYLHLRHLRALYVWLTQHPHETPPVGAGVWGDLFDRLYKYQ
KTQRQSQARLRDIIRRVQDSCEAMRDAVVMLDGHGDLEWWNTAATQMLGFQSPHDRGQHITNFLRDPRFVAYFNARDYRE
PLTLASPLRDDVTLQYQITLFGDNERLVMARDISRLHRLEEMRRDFVANVSHELRTPLTVLTGYLETYLDNADQLPPRWQ
RGLGQMQEQSQRMQRLVEDLLLLSKLETDQTRDDPVPLDMAALLANIRDDAAALCNGSHDVRLEIDDDRHLLGADGEIRS
AVSNLVFNAVRYTPSGSTVTLRWKAWKEGAAVEVEDDGEGIDPVHLPRLTERFYRVDKGRSAANGGTGLGLAIVKHVLLR
HDAHLDIDSHPGQGALFRCVFPAARLNAAPAERRAVGGD
>Mature_439_residues
MHYWTNELWRLAYLVVGLGALGWLLGEPGWGLAAGLGLYVYLHLRHLRALYVWLTQHPHETPPVGAGVWGDLFDRLYKYQ
KTQRQSQARLRDIIRRVQDSCEAMRDAVVMLDGHGDLEWWNTAATQMLGFQSPHDRGQHITNFLRDPRFVAYFNARDYRE
PLTLASPLRDDVTLQYQITLFGDNERLVMARDISRLHRLEEMRRDFVANVSHELRTPLTVLTGYLETYLDNADQLPPRWQ
RGLGQMQEQSQRMQRLVEDLLLLSKLETDQTRDDPVPLDMAALLANIRDDAAALCNGSHDVRLEIDDDRHLLGADGEIRS
AVSNLVFNAVRYTPSGSTVTLRWKAWKEGAAVEVEDDGEGIDPVHLPRLTERFYRVDKGRSAANGGTGLGLAIVKHVLLR
HDAHLDIDSHPGQGALFRCVFPAARLNAAPAERRAVGGD

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=402, Percent_Identity=41.2935323383085, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=29.4117647058824, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=31.4159292035398, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=28.7610619469027, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=29.2035398230088, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788549, Length=347, Percent_Identity=23.6311239193084, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=28.5140562248996, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789403, Length=219, Percent_Identity=31.0502283105023, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=25.3275109170306, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=225, Percent_Identity=30.2222222222222, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790861, Length=195, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790551, Length=226, Percent_Identity=29.2035398230088, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789808, Length=247, Percent_Identity=29.1497975708502, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788279, Length=248, Percent_Identity=22.5806451612903, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49786; Mature: 49786

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYWTNELWRLAYLVVGLGALGWLLGEPGWGLAAGLGLYVYLHLRHLRALYVWLTQHPHE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TPPVGAGVWGDLFDRLYKYQKTQRQSQARLRDIIRRVQDSCEAMRDAVVMLDGHGDLEWW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHH
NTAATQMLGFQSPHDRGQHITNFLRDPRFVAYFNARDYREPLTLASPLRDDVTLQYQITL
HHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEE
FGDNERLVMARDISRLHRLEEMRRDFVANVSHELRTPLTVLTGYLETYLDNADQLPPRWQ
EECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHH
RGLGQMQEQSQRMQRLVEDLLLLSKLETDQTRDDPVPLDMAALLANIRDDAAALCNGSHD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCE
VRLEIDDDRHLLGADGEIRSAVSNLVFNAVRYTPSGSTVTLRWKAWKEGAAVEVEDDGEG
EEEEECCCCEEECCCHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCCCEEEECCCCCC
IDPVHLPRLTERFYRVDKGRSAANGGTGLGLAIVKHVLLRHDAHLDIDSHPGQGALFRCV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
FPAARLNAAPAERRAVGGD
CCHHHCCCCCHHCCCCCCC
>Mature Secondary Structure
MHYWTNELWRLAYLVVGLGALGWLLGEPGWGLAAGLGLYVYLHLRHLRALYVWLTQHPHE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TPPVGAGVWGDLFDRLYKYQKTQRQSQARLRDIIRRVQDSCEAMRDAVVMLDGHGDLEWW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHH
NTAATQMLGFQSPHDRGQHITNFLRDPRFVAYFNARDYREPLTLASPLRDDVTLQYQITL
HHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEE
FGDNERLVMARDISRLHRLEEMRRDFVANVSHELRTPLTVLTGYLETYLDNADQLPPRWQ
EECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHH
RGLGQMQEQSQRMQRLVEDLLLLSKLETDQTRDDPVPLDMAALLANIRDDAAALCNGSHD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCE
VRLEIDDDRHLLGADGEIRSAVSNLVFNAVRYTPSGSTVTLRWKAWKEGAAVEVEDDGEG
EEEEECCCCEEECCCHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCCCEEEECCCCCC
IDPVHLPRLTERFYRVDKGRSAANGGTGLGLAIVKHVLLRHDAHLDIDSHPGQGALFRCV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
FPAARLNAAPAERRAVGGD
CCHHHCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043; 2115874 [H]