Click here to switch to the map view.

The map label for this gene is panC

Identifier: 92115181

GI number: 92115181

Start: 3415228

End: 3416079

Strand: Direct

Name: panC

Synonym: Csal_3066

Alternate gene names: 92115181

Gene position: 3415228-3416079 (Clockwise)

Preceding gene: 92115180

Following gene: 92115182

Centisome position: 92.39

GC content: 66.78

Gene sequence:

>852_bases
ATGTTGACGCTGTCCGACATCGGCGAGCTGCGCAATCATCTGCATGCGGCGCGGCGTGATGCCAAGCGTATTGCGCTCGT
TCCCACCATGGGCAACCTGCACGCGGGCCATCTGGCCTTGGTCGACGCGGCGCGGCGCGACGCGGACGTGGTCGTCGCGA
CCATCTTCGTCAATCCGCTCCAGTTCGGCGCCAATGAAGACTTCGCGAGCTATCCGCGCACCCTCGAGGCGGATGCCCAG
GCACTCGCGTCGCACGGTTGCGATCTCGTGTTCACGCCGCGCACCGACGCCCTCTACCCGCACGGCCTCGAGGCACATAC
CCAGGTCAGCGTGCCCGACGTCTCGGAAGGACTGTGCGGCGCCAATCGTCCAGGGCACTTCACCGGCGTGGCCACGGTCG
TCAGCCTGCTTTTCAACCTGGTGCAGCCGGACGCGGCCTATTTCGGCCGCAAGGATTACCAGCAGTTCATGGTCATCCGT
AAACTGGTGGCGGATCTGCACTTCCCGATCGAGATCGTCGGTGTCCCCACGCAACGTGCCGAGGACGGCCTGGCACTGTC
GTCACGCAATGGCTACCTGAGTGCCGCGGAGCGCCAGCGTGCGCCGGCGCTCTACCGCACGCTATGCCAAGTGCATGACG
CACTGCGCGCCGGCGAGGCGCCGCCGACCGCCCTGCGTGACGGTCTGGCGGCCCTCGCCGAGCAGGGCTTCAAACCCGAT
TACCTGGAGCTGCGTCGCGCCCAGGATCTCGGCCCCATCGCCCCCGATACCCAGGAAGCGATCCTGCTGGTCGCCGCGCA
TCTCGGCACCACCCGCTTGATCGACAACCTTGCGGTCAGCTTGCCGCGTTGA

Upstream 100 bases:

>100_bases
AGAATTTTCTGGCGGGTCGTGACAGCATCCAGGCGGCGTTCGAAGCCTACCGCGATGCCGTCAAGACGCGTCAATTTCCC
GCCGAGGAGCATTGTTTCTG

Downstream 100 bases:

>100_bases
CCGTCGACGCGGCGTCACGACGAGGTTTTTCATGTACACCATCATGCTCAAGGCCAAACTGCACATGGCGCGCGTCACTC
ACGCAGTGCTCGACTACGAG

Product: pantothenate synthetase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLTLSDIGELRNHLHAARRDAKRIALVPTMGNLHAGHLALVDAARRDADVVVATIFVNPLQFGANEDFASYPRTLEADAQ
ALASHGCDLVFTPRTDALYPHGLEAHTQVSVPDVSEGLCGANRPGHFTGVATVVSLLFNLVQPDAAYFGRKDYQQFMVIR
KLVADLHFPIEIVGVPTQRAEDGLALSSRNGYLSAAERQRAPALYRTLCQVHDALRAGEAPPTALRDGLAALAEQGFKPD
YLELRRAQDLGPIAPDTQEAILLVAAHLGTTRLIDNLAVSLPR

Sequences:

>Translated_283_residues
MLTLSDIGELRNHLHAARRDAKRIALVPTMGNLHAGHLALVDAARRDADVVVATIFVNPLQFGANEDFASYPRTLEADAQ
ALASHGCDLVFTPRTDALYPHGLEAHTQVSVPDVSEGLCGANRPGHFTGVATVVSLLFNLVQPDAAYFGRKDYQQFMVIR
KLVADLHFPIEIVGVPTQRAEDGLALSSRNGYLSAAERQRAPALYRTLCQVHDALRAGEAPPTALRDGLAALAEQGFKPD
YLELRRAQDLGPIAPDTQEAILLVAAHLGTTRLIDNLAVSLPR
>Mature_283_residues
MLTLSDIGELRNHLHAARRDAKRIALVPTMGNLHAGHLALVDAARRDADVVVATIFVNPLQFGANEDFASYPRTLEADAQ
ALASHGCDLVFTPRTDALYPHGLEAHTQVSVPDVSEGLCGANRPGHFTGVATVVSLLFNLVQPDAAYFGRKDYQQFMVIR
KLVADLHFPIEIVGVPTQRAEDGLALSSRNGYLSAAERQRAPALYRTLCQVHDALRAGEAPPTALRDGLAALAEQGFKPD
YLELRRAQDLGPIAPDTQEAILLVAAHLGTTRLIDNLAVSLPR

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=282, Percent_Identity=53.1914893617021, Blast_Score=296, Evalue=7e-82,
Organism=Saccharomyces cerevisiae, GI6322046, Length=304, Percent_Identity=33.8815789473684, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_CHRSD (Q1QSZ8)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_575109.1
- ProteinModelPortal:   Q1QSZ8
- SMR:   Q1QSZ8
- STRING:   Q1QSZ8
- GeneID:   4028870
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_3066
- NMPDR:   fig|290398.4.peg.2448
- eggNOG:   COG0414
- HOGENOM:   HBG428839
- OMA:   RLIDNFT
- BioCyc:   CSAL290398:CSAL_3066-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 30602; Mature: 30602

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: ACT_SITE 37-37 BINDING 61-61 BINDING 61-61 BINDING 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLSDIGELRNHLHAARRDAKRIALVPTMGNLHAGHLALVDAARRDADVVVATIFVNPL
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEECHH
QFGANEDFASYPRTLEADAQALASHGCDLVFTPRTDALYPHGLEAHTQVSVPDVSEGLCG
HCCCCCCHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCEECCCCCCCCCCC
ANRPGHFTGVATVVSLLFNLVQPDAAYFGRKDYQQFMVIRKLVADLHFPIEIVGVPTQRA
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
EDGLALSSRNGYLSAAERQRAPALYRTLCQVHDALRAGEAPPTALRDGLAALAEQGFKPD
CCCCEEECCCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCH
YLELRRAQDLGPIAPDTQEAILLVAAHLGTTRLIDNLAVSLPR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLTLSDIGELRNHLHAARRDAKRIALVPTMGNLHAGHLALVDAARRDADVVVATIFVNPL
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEECHH
QFGANEDFASYPRTLEADAQALASHGCDLVFTPRTDALYPHGLEAHTQVSVPDVSEGLCG
HCCCCCCHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCEECCCCCCCCCCC
ANRPGHFTGVATVVSLLFNLVQPDAAYFGRKDYQQFMVIRKLVADLHFPIEIVGVPTQRA
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
EDGLALSSRNGYLSAAERQRAPALYRTLCQVHDALRAGEAPPTALRDGLAALAEQGFKPD
CCCCEEECCCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCH
YLELRRAQDLGPIAPDTQEAILLVAAHLGTTRLIDNLAVSLPR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA