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The map label for this gene is tas [H]

Identifier: 92115160

GI number: 92115160

Start: 3389292

End: 3390323

Strand: Direct

Name: tas [H]

Synonym: Csal_3045

Alternate gene names: 92115160

Gene position: 3389292-3390323 (Clockwise)

Preceding gene: 92115157

Following gene: 92115161

Centisome position: 91.69

GC content: 64.63

Gene sequence:

>1032_bases
ATGCAGACACGTCCTCTCGGCCAGACCGGCATGCATGTCAGCCGACTTTGCCTCGGCACCATGACCTTTGGCGAGCAGAA
CAGCGAGGCCGAAGCACACGCTCAGCTCGATCGCGCCACGGCCGCGGGCATCAATTTCATCGACACCGCCGAAATGTACC
CCGTCCCGCCCAAGGCGGAAACGCAAGGGCGCACCGAGGCGTACATCGGGAGCTGGCTCAAGGCACGCGGCAAGCGCGAC
GACCTGATTCTCGCGACCAAGGCAGCAGGGCCGGGGCTCGACCATATACGGGGCGGACCGCGCCTGACCCGCGACCATCT
GCACCGCGCCGTCGACGACAGCCTGGCGCGACTGCAGACCGACTATATCGACCTGTACCAGCTTCACTGGCCCGACCGCA
ACGCCAACTTCTTCGGCAAGCTGGGTTATCAGCATGACGAGAGCGAGAACGCCACTCCCCTGGCCGAATCCCTCCAGGCC
TTGAAGGAGCTCGTCGACGCCGGCAAGATCCGCGCCATCGGCCTGTCCAACGAGACCCCCTGGGGCGTGATGCAGAGCCT
GCGACTCGCCGACACCCTGGGCGTGCCGCGCGTGGCCAGCGTGCAGAACCCCTACAACCTGCTCAACCGCAGCTTCGAGG
TGGGCCTGGCGGAAATCGCCCATCGCGAGGATGTCGGCTTGCTGGCTTATTCACCGCTGGCATTCGGCGCGCTGACCGGC
AAATATCTCGATGGCGCACGGCCGCCCCAGGGACGACTGACGTTGTTCGAACGCTTCCAGCGCTACACGTCGGACCTCGC
CGAGAAGGCGATCCACGCCTATGTCGATATCGCCCGGGAGCACGGACTCGATCCCGCCCAGATGGCACTGGCCTACGTCA
ATTCACGCTCGTTCTTGACCAGCAACATCATCGGCGCGACCACGCTCGACCAGCTAGAGTCCAATCTGGCCAGCGAGACA
CTGACGCTGGATGACAGCGTGCTGGAAGCCATCGAAAACGTGCACCGTCAGCACCCCAACCCCTGCCCCTGA

Upstream 100 bases:

>100_bases
GCCTACCCCCGGGACGACTCAACCCCCCGGTTTGCCGCCCGCATGCCGCCCCGCTACCATGCCGATTCCACCCATCTTGT
GAACCCGTGCGGAGACTCCG

Downstream 100 bases:

>100_bases
CGCACGTCGAGCGTGTCTATCGAAGCGATAGACACGCTGTCATCGGCCCCACCGGGACAGCTTGTTATACTGCTCGTAAC
GAGTCACACGATTTTGACGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MQTRPLGQTGMHVSRLCLGTMTFGEQNSEAEAHAQLDRATAAGINFIDTAEMYPVPPKAETQGRTEAYIGSWLKARGKRD
DLILATKAAGPGLDHIRGGPRLTRDHLHRAVDDSLARLQTDYIDLYQLHWPDRNANFFGKLGYQHDESENATPLAESLQA
LKELVDAGKIRAIGLSNETPWGVMQSLRLADTLGVPRVASVQNPYNLLNRSFEVGLAEIAHREDVGLLAYSPLAFGALTG
KYLDGARPPQGRLTLFERFQRYTSDLAEKAIHAYVDIAREHGLDPAQMALAYVNSRSFLTSNIIGATTLDQLESNLASET
LTLDDSVLEAIENVHRQHPNPCP

Sequences:

>Translated_343_residues
MQTRPLGQTGMHVSRLCLGTMTFGEQNSEAEAHAQLDRATAAGINFIDTAEMYPVPPKAETQGRTEAYIGSWLKARGKRD
DLILATKAAGPGLDHIRGGPRLTRDHLHRAVDDSLARLQTDYIDLYQLHWPDRNANFFGKLGYQHDESENATPLAESLQA
LKELVDAGKIRAIGLSNETPWGVMQSLRLADTLGVPRVASVQNPYNLLNRSFEVGLAEIAHREDVGLLAYSPLAFGALTG
KYLDGARPPQGRLTLFERFQRYTSDLAEKAIHAYVDIAREHGLDPAQMALAYVNSRSFLTSNIIGATTLDQLESNLASET
LTLDDSVLEAIENVHRQHPNPCP
>Mature_343_residues
MQTRPLGQTGMHVSRLCLGTMTFGEQNSEAEAHAQLDRATAAGINFIDTAEMYPVPPKAETQGRTEAYIGSWLKARGKRD
DLILATKAAGPGLDHIRGGPRLTRDHLHRAVDDSLARLQTDYIDLYQLHWPDRNANFFGKLGYQHDESENATPLAESLQA
LKELVDAGKIRAIGLSNETPWGVMQSLRLADTLGVPRVASVQNPYNLLNRSFEVGLAEIAHREDVGLLAYSPLAFGALTG
KYLDGARPPQGRLTLFERFQRYTSDLAEKAIHAYVDIAREHGLDPAQMALAYVNSRSFLTSNIIGATTLDQLESNLASET
LTLDDSVLEAIENVHRQHPNPCP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=350, Percent_Identity=29.7142857142857, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27436962, Length=350, Percent_Identity=29.7142857142857, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI27436966, Length=350, Percent_Identity=29.7142857142857, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI27436969, Length=352, Percent_Identity=28.6931818181818, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4504825, Length=349, Percent_Identity=28.6532951289398, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=27.8787878787879, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI223718702, Length=349, Percent_Identity=28.080229226361, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI41152114, Length=348, Percent_Identity=28.735632183908, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41327764, Length=345, Percent_Identity=28.4057971014493, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=57.2254335260116, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI87081735, Length=359, Percent_Identity=32.5905292479109, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789375, Length=344, Percent_Identity=31.6860465116279, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788070, Length=344, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787674, Length=331, Percent_Identity=27.4924471299094, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788081, Length=324, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=347, Percent_Identity=28.2420749279539, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=319, Percent_Identity=26.9592476489028, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319951, Length=349, Percent_Identity=25.7879656160458, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=377, Percent_Identity=24.6684350132626, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=271, Percent_Identity=25.4612546125461, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321052, Length=136, Percent_Identity=36.7647058823529, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37762; Mature: 37762

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTRPLGQTGMHVSRLCLGTMTFGEQNSEAEAHAQLDRATAAGINFIDTAEMYPVPPKAE
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TQGRTEAYIGSWLKARGKRDDLILATKAAGPGLDHIRGGPRLTRDHLHRAVDDSLARLQT
CCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQLHWPDRNANFFGKLGYQHDESENATPLAESLQALKELVDAGKIRAIGLSNETP
HHHHEEEEECCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
WGVMQSLRLADTLGVPRVASVQNPYNLLNRSFEVGLAEIAHREDVGLLAYSPLAFGALTG
HHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
KYLDGARPPQGRLTLFERFQRYTSDLAEKAIHAYVDIAREHGLDPAQMALAYVNSRSFLT
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
SNIIGATTLDQLESNLASETLTLDDSVLEAIENVHRQHPNPCP
HHCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQTRPLGQTGMHVSRLCLGTMTFGEQNSEAEAHAQLDRATAAGINFIDTAEMYPVPPKAE
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TQGRTEAYIGSWLKARGKRDDLILATKAAGPGLDHIRGGPRLTRDHLHRAVDDSLARLQT
CCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQLHWPDRNANFFGKLGYQHDESENATPLAESLQALKELVDAGKIRAIGLSNETP
HHHHEEEEECCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
WGVMQSLRLADTLGVPRVASVQNPYNLLNRSFEVGLAEIAHREDVGLLAYSPLAFGALTG
HHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
KYLDGARPPQGRLTLFERFQRYTSDLAEKAIHAYVDIAREHGLDPAQMALAYVNSRSFLT
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
SNIIGATTLDQLESNLASETLTLDDSVLEAIENVHRQHPNPCP
HHCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]