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The map label for this gene is siaT [H]

Identifier: 92115094

GI number: 92115094

Start: 3315950

End: 3317230

Strand: Direct

Name: siaT [H]

Synonym: Csal_2978

Alternate gene names: 92115094

Gene position: 3315950-3317230 (Clockwise)

Preceding gene: 92115093

Following gene: 92115095

Centisome position: 89.7

GC content: 64.01

Gene sequence:

>1281_bases
ATGGAAGTCTTCATTCTCTTCAGCGTATTCATCGTGCTGCTGCTGATCGGCATCCCCATCGCCTTTTCCCTGGGCATCGC
CTCGCTCTCCTATCTCCTGCTCGCGGACATCTCGCTGACCATCATCCCGCAGCGAATGTACGGCGGCATCGACACGTTCG
TGCTGCTGTGCATCCCCGGCTTCGTGCTGGCCGGCAACCTGATGAACGTCGGCAACATCACCGACCATATCGTGCGTTTC
TCGAACGCGCTGGTGGGGCACATCCGTGGCGGCCTGGGGCTGGCCAACGTGGGGGGCTCGATGATCTTCGGCGGGATCTC
CGGCACCGCCGTGGCCGACGCGGCGAGCATCGGCTCGGTGATGATCCCCGGCATGTCCCGCGCCGGGTACGACAAGCCCT
TCGCCGCCGCGGTGACCGCCGCCTCCTCGACGGTGGGCCCGATCATCCCGCCCAGCGTGCCGATGATCATCGCCGGCTCG
CTGTCCGGCGTCTCGGTGGGACGCATGTTCCTGGCCGGCGCCATCCCCGGCCTGCTGCTGGGCCTGGCGATGATGATCAC
CGTGTACATCCTGGCGGTGAAACGCGGGTACCCGCGCGAGAAACGCTCCACGTTCCGGCAACTGGTGCTGGAAGGACGCA
GTGCCTTCTGGGCATTGCTGATGACCTTCATCATTCTCTACGGGATCGTCGGCGGCGTTTTCACCCCCACCGAAGCCTCG
ATCGTCGCCAGCCTGTATGCCCTGGTGATCGGCATGTTCGTCTACAAGGGCATCACCTGGCGCAATCTGCCGCAGATCGT
CATCGACACCGTCCTGACCTCGGGGTCGCTGATGATCCTGGTCGGCCTGGCCAATCTGTTCGGCTGGATCCTCACCAGCC
AGCAGATTCCGCAGATGATCGCCGACCAGATCCTGGCCATCAGCGACAACCCGCTGGTCGTGATCCTGATCCTCAATCTG
ATCCTGCTGGTGGTGGGTACCTTCATGGAAACCATCGCTGCCCTGATCATCCTGTTCCCGGCGCTGCTGGGCGTCGCCAC
CGGGGTCGGCATGGATCCCGTGCACTTCGGCCTGATGGCGGTGCTCAACCTGATGATCGGACTGACCACACCGCCGCTCG
GGGTCTGCCTGTTCGTGGTCGCCGGCATCGGCAAGCTGCCCATGCTGCGCGTGGCCCGTGCCATCGTGCCGTTTCTGATC
TGCAATCTCGTGGTGCTGCTGCTGGTCGCATACATCCCCGCCCTGTCACTCTGGCTACCCAACCTGCTGCTCGGGGAGTG
A

Upstream 100 bases:

>100_bases
TTCTCTTTGGCTTGACCGCCCTCTATGCGGTGATCGGCGTCATCGAAGCCGGCGTGGCGATCAAGCGCGATGCATCCGCC
CAGCGTCCGGAGCCTCACTG

Downstream 100 bases:

>100_bases
TCGTTCATGACACCGACATCGATACCCAGCGTCCATGCGCCAGCCGAGGTGGGCATCGTGCATCTCGGCCTGGGCGCCTT
CCACCGCGCCCACCAGGCGG

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MEVFILFSVFIVLLLIGIPIAFSLGIASLSYLLLADISLTIIPQRMYGGIDTFVLLCIPGFVLAGNLMNVGNITDHIVRF
SNALVGHIRGGLGLANVGGSMIFGGISGTAVADAASIGSVMIPGMSRAGYDKPFAAAVTAASSTVGPIIPPSVPMIIAGS
LSGVSVGRMFLAGAIPGLLLGLAMMITVYILAVKRGYPREKRSTFRQLVLEGRSAFWALLMTFIILYGIVGGVFTPTEAS
IVASLYALVIGMFVYKGITWRNLPQIVIDTVLTSGSLMILVGLANLFGWILTSQQIPQMIADQILAISDNPLVVILILNL
ILLVVGTFMETIAALIILFPALLGVATGVGMDPVHFGLMAVLNLMIGLTTPPLGVCLFVVAGIGKLPMLRVARAIVPFLI
CNLVVLLLVAYIPALSLWLPNLLLGE

Sequences:

>Translated_426_residues
MEVFILFSVFIVLLLIGIPIAFSLGIASLSYLLLADISLTIIPQRMYGGIDTFVLLCIPGFVLAGNLMNVGNITDHIVRF
SNALVGHIRGGLGLANVGGSMIFGGISGTAVADAASIGSVMIPGMSRAGYDKPFAAAVTAASSTVGPIIPPSVPMIIAGS
LSGVSVGRMFLAGAIPGLLLGLAMMITVYILAVKRGYPREKRSTFRQLVLEGRSAFWALLMTFIILYGIVGGVFTPTEAS
IVASLYALVIGMFVYKGITWRNLPQIVIDTVLTSGSLMILVGLANLFGWILTSQQIPQMIADQILAISDNPLVVILILNL
ILLVVGTFMETIAALIILFPALLGVATGVGMDPVHFGLMAVLNLMIGLTTPPLGVCLFVVAGIGKLPMLRVARAIVPFLI
CNLVVLLLVAYIPALSLWLPNLLLGE
>Mature_426_residues
MEVFILFSVFIVLLLIGIPIAFSLGIASLSYLLLADISLTIIPQRMYGGIDTFVLLCIPGFVLAGNLMNVGNITDHIVRF
SNALVGHIRGGLGLANVGGSMIFGGISGTAVADAASIGSVMIPGMSRAGYDKPFAAAVTAASSTVGPIIPPSVPMIIAGS
LSGVSVGRMFLAGAIPGLLLGLAMMITVYILAVKRGYPREKRSTFRQLVLEGRSAFWALLMTFIILYGIVGGVFTPTEAS
IVASLYALVIGMFVYKGITWRNLPQIVIDTVLTSGSLMILVGLANLFGWILTSQQIPQMIADQILAISDNPLVVILILNL
ILLVVGTFMETIAALIILFPALLGVATGVGMDPVHFGLMAVLNLMIGLTTPPLGVCLFVVAGIGKLPMLRVARAIVPFLI
CNLVVLLLVAYIPALSLWLPNLLLGE

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=403, Percent_Identity=36.4764267990074, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44816; Mature: 44816

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00457 NA_SOLUT_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVFILFSVFIVLLLIGIPIAFSLGIASLSYLLLADISLTIIPQRMYGGIDTFVLLCIPG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCHHHHHHHHHHH
FVLAGNLMNVGNITDHIVRFSNALVGHIRGGLGLANVGGSMIFGGISGTAVADAASIGSV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEECCCCCHHHHHHHHHCCE
MIPGMSRAGYDKPFAAAVTAASSTVGPIIPPSVPMIIAGSLSGVSVGRMFLAGAIPGLLL
ECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
GLAMMITVYILAVKRGYPREKRSTFRQLVLEGRSAFWALLMTFIILYGIVGGVFTPTEAS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IVASLYALVIGMFVYKGITWRNLPQIVIDTVLTSGSLMILVGLANLFGWILTSQQIPQMI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADQILAISDNPLVVILILNLILLVVGTFMETIAALIILFPALLGVATGVGMDPVHFGLMA
HHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VLNLMIGLTTPPLGVCLFVVAGIGKLPMLRVARAIVPFLICNLVVLLLVAYIPALSLWLP
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLLGE
HHHCCC
>Mature Secondary Structure
MEVFILFSVFIVLLLIGIPIAFSLGIASLSYLLLADISLTIIPQRMYGGIDTFVLLCIPG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCHHHHHHHHHHH
FVLAGNLMNVGNITDHIVRFSNALVGHIRGGLGLANVGGSMIFGGISGTAVADAASIGSV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEECCCCCHHHHHHHHHCCE
MIPGMSRAGYDKPFAAAVTAASSTVGPIIPPSVPMIIAGSLSGVSVGRMFLAGAIPGLLL
ECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
GLAMMITVYILAVKRGYPREKRSTFRQLVLEGRSAFWALLMTFIILYGIVGGVFTPTEAS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IVASLYALVIGMFVYKGITWRNLPQIVIDTVLTSGSLMILVGLANLFGWILTSQQIPQMI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADQILAISDNPLVVILILNLILLVVGTFMETIAALIILFPALLGVATGVGMDPVHFGLMA
HHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VLNLMIGLTTPPLGVCLFVVAGIGKLPMLRVARAIVPFLICNLVVLLLVAYIPALSLWLP
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLLGE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]