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The map label for this gene is mdaB [H]

Identifier: 92114918

GI number: 92114918

Start: 3130425

End: 3131009

Strand: Direct

Name: mdaB [H]

Synonym: Csal_2801

Alternate gene names: 92114918

Gene position: 3130425-3131009 (Clockwise)

Preceding gene: 92114917

Following gene: 92114919

Centisome position: 84.68

GC content: 62.91

Gene sequence:

>585_bases
ATGAAGATTCTATTGATCAACGGCGCCAAGGCCTTCGCGCATTCCGGCGGCCGCTACAACGACACCCTGCACGACGTGGC
ACGCGGCGAACTCGCCGAACTCGGCCACGAGATCCGCGAGACCCGCATCGATGACGGCTACGACACCGATACCGAAGTCG
AGAAATTCCTGTGGGCCGACGTCATCGTCTACCAGATGCCCGGCTGGTGGATGGGCGCTCCCTGGACGGTCAAGCGCTAT
ATCGACGAAGTCTTCACCGCCGGCCACGGATCGCTTTATGCCAGCGACGGGCGCTCGCGCAAGGATCCCAGCCGTCAGTA
CGGCAGCGGCGGCCTGCTGCAGGGGCGGCGTTACATGCTCTCGCTGACCTGGAACGCGCCACTCGAGGCATTCGACGAGC
CCGGCAACTTCTTCGAGGGCCAGGGCGTCGACGGGGTATACTTCCCCTTCCATAAATCCCAGGAATTCGTGGGCCTGGCG
GCCATGCCGACCTTCATCGCCAACGATGTCATCAAGGCCCCCGACATCGATGGTCATGTCGATGCCTATCGCGCCCATCT
GCGCGAGCACTTTGCCAACGCCTGA

Upstream 100 bases:

>100_bases
CCTGCAAGAATGTTTTGCAATTACACCACTTTATCGCAAGGCAGCGACTCGGCAGACTGCCCCACCTTTGAAATCACGTT
CACACCGAGTCGAACCCTTC

Downstream 100 bases:

>100_bases
ACGCCGACGACGACTCGCCCCCGGCCGGCGCTCCACGGCGCCGGCTACAATGTAGCTCCCTGGTCCTGCCGGGCGTTTCA
GCCTTCAAGGCACGGCAAGC

Product: NAD(P)H dehydrogenase (quinone)

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKILLINGAKAFAHSGGRYNDTLHDVARGELAELGHEIRETRIDDGYDTDTEVEKFLWADVIVYQMPGWWMGAPWTVKRY
IDEVFTAGHGSLYASDGRSRKDPSRQYGSGGLLQGRRYMLSLTWNAPLEAFDEPGNFFEGQGVDGVYFPFHKSQEFVGLA
AMPTFIANDVIKAPDIDGHVDAYRAHLREHFANA

Sequences:

>Translated_194_residues
MKILLINGAKAFAHSGGRYNDTLHDVARGELAELGHEIRETRIDDGYDTDTEVEKFLWADVIVYQMPGWWMGAPWTVKRY
IDEVFTAGHGSLYASDGRSRKDPSRQYGSGGLLQGRRYMLSLTWNAPLEAFDEPGNFFEGQGVDGVYFPFHKSQEFVGLA
AMPTFIANDVIKAPDIDGHVDAYRAHLREHFANA
>Mature_194_residues
MKILLINGAKAFAHSGGRYNDTLHDVARGELAELGHEIRETRIDDGYDTDTEVEKFLWADVIVYQMPGWWMGAPWTVKRY
IDEVFTAGHGSLYASDGRSRKDPSRQYGSGGLLQGRRYMLSLTWNAPLEAFDEPGNFFEGQGVDGVYFPFHKSQEFVGLA
AMPTFIANDVIKAPDIDGHVDAYRAHLREHFANA

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=189, Percent_Identity=66.6666666666667, Blast_Score=281, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 21802; Mature: 21802

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLINGAKAFAHSGGRYNDTLHDVARGELAELGHEIRETRIDDGYDTDTEVEKFLWAD
CEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VIVYQMPGWWMGAPWTVKRYIDEVFTAGHGSLYASDGRSRKDPSRQYGSGGLLQGRRYML
HHEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHCCCCCCCCCCEEEE
SLTWNAPLEAFDEPGNFFEGQGVDGVYFPFHKSQEFVGLAAMPTFIANDVIKAPDIDGHV
EEEECCCHHHCCCCCCEECCCCCCCEECCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCHH
DAYRAHLREHFANA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKILLINGAKAFAHSGGRYNDTLHDVARGELAELGHEIRETRIDDGYDTDTEVEKFLWAD
CEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VIVYQMPGWWMGAPWTVKRYIDEVFTAGHGSLYASDGRSRKDPSRQYGSGGLLQGRRYML
HHEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHCCCCCCCCCCEEEE
SLTWNAPLEAFDEPGNFFEGQGVDGVYFPFHKSQEFVGLAAMPTFIANDVIKAPDIDGHV
EEEECCCHHHCCCCCCEECCCCCCCEECCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCHH
DAYRAHLREHFANA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]