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The map label for this gene is hexR [H]

Identifier: 92114860

GI number: 92114860

Start: 3075037

End: 3075897

Strand: Direct

Name: hexR [H]

Synonym: Csal_2742

Alternate gene names: 92114860

Gene position: 3075037-3075897 (Clockwise)

Preceding gene: 92114852

Following gene: 92114861

Centisome position: 83.18

GC content: 65.04

Gene sequence:

>861_bases
ATGCCAGCCTTCGACTTGATCGACCGTATCCGCTCACGCCTGGACGAGCTCAATCGTTCCGAACGCAAAGTGGCCGACGT
GATTCTCAATGATCCCGCCGCCGCCACCGGCATGAGCATCGCCACGCTGGCACAGGCGGCCGCGGTCAGCGAGCCCACGG
TCAACCGCTTCTGCCGTAACTTCGACGCCAAGGGATACCCCGATTTCAAGATCAAGCTGGCTCAAAGCCTAGCCGGGGGC
ACGCCCTATGTCAGCCGTAGCGTGGAACGCGACGACGATGCCTCGAGCTACGGGGACAAGATATTCGGCGCGACCATCGC
CGCCCTCGACGACGCCCGGCGCGCGCTGGATGCCAAACGCGTCGAACGTGCCGTCGATTACCTGATTCAGGCCAAGCAGA
TCAGCTTCTTCGGTCTGGGCGCCTCGGGCCCCGTCGCTCAGGACGCGCAGCACAAGTTCTTTCGCTTCAACCTGCCCGTC
ACCGCCTACGAAGACGTGCTGATGCAGCGCATGGTGGCCGCCGCCACGCATACCGGCGACGTCATCGTCATCGTCTCGTA
CACCGGGCGCACCCGGGAACTGGTCGAGATCGCCCGTGTCGCCCGCGACAATGGCGCCATCGTGCTGGGCATCACCGCGC
CCGACTCGCCGCTCGCCCACGAGTGCACGGAAACCCTCGAGGTCATCACGCCGGAGGATACCGACGTCTACATGCCGATG
ACCTCGCGCATGATCCACCTGGCCCTGATCGACGTGCTGGCGACCGGGGTCACGCTGCGTCGCGGCGAGGATTTCCTGCC
GCATCTCAAGAAGATCAAGGACAGCCTGCAGGCCACGCGCTTCCCGGCGCGCGAGGACTGA

Upstream 100 bases:

>100_bases
GTTACTTGACTAGGTCGTGTTCGAAAGGGCGGCAAACGCAGCCCGCCTTCGCACACGGCCCCGCTTCGACCCCCTTGGCA
GACAGAGACGCCCATTACGC

Downstream 100 bases:

>100_bases
AACGCGTCCCCATCAACGCCGGCTCTATCAAGGAGTATGCCCATGCGCTGGCTCGTCGCCTGCCTGTTGTTCGTCGTCAG
CACGGCCGTCCTGGCCGACA

Product: DNA-binding transcriptional regulator HexR

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPAFDLIDRIRSRLDELNRSERKVADVILNDPAAATGMSIATLAQAAAVSEPTVNRFCRNFDAKGYPDFKIKLAQSLAGG
TPYVSRSVERDDDASSYGDKIFGATIAALDDARRALDAKRVERAVDYLIQAKQISFFGLGASGPVAQDAQHKFFRFNLPV
TAYEDVLMQRMVAAATHTGDVIVIVSYTGRTRELVEIARVARDNGAIVLGITAPDSPLAHECTETLEVITPEDTDVYMPM
TSRMIHLALIDVLATGVTLRRGEDFLPHLKKIKDSLQATRFPARED

Sequences:

>Translated_286_residues
MPAFDLIDRIRSRLDELNRSERKVADVILNDPAAATGMSIATLAQAAAVSEPTVNRFCRNFDAKGYPDFKIKLAQSLAGG
TPYVSRSVERDDDASSYGDKIFGATIAALDDARRALDAKRVERAVDYLIQAKQISFFGLGASGPVAQDAQHKFFRFNLPV
TAYEDVLMQRMVAAATHTGDVIVIVSYTGRTRELVEIARVARDNGAIVLGITAPDSPLAHECTETLEVITPEDTDVYMPM
TSRMIHLALIDVLATGVTLRRGEDFLPHLKKIKDSLQATRFPARED
>Mature_285_residues
PAFDLIDRIRSRLDELNRSERKVADVILNDPAAATGMSIATLAQAAAVSEPTVNRFCRNFDAKGYPDFKIKLAQSLAGGT
PYVSRSVERDDDASSYGDKIFGATIAALDDARRALDAKRVERAVDYLIQAKQISFFGLGASGPVAQDAQHKFFRFNLPVT
AYEDVLMQRMVAAATHTGDVIVIVSYTGRTRELVEIARVARDNGAIVLGITAPDSPLAHECTETLEVITPEDTDVYMPMT
SRMIHLALIDVLATGVTLRRGEDFLPHLKKIKDSLQATRFPARED

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=278, Percent_Identity=53.5971223021583, Blast_Score=318, Evalue=2e-88,
Organism=Escherichia coli, GI87082369, Length=249, Percent_Identity=23.2931726907631, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788767, Length=259, Percent_Identity=24.7104247104247, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082130, Length=235, Percent_Identity=30.6382978723404, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31385; Mature: 31254

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFDLIDRIRSRLDELNRSERKVADVILNDPAAATGMSIATLAQAAAVSEPTVNRFCRN
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHCCCHHHHHHHHC
FDAKGYPDFKIKLAQSLAGGTPYVSRSVERDDDASSYGDKIFGATIAALDDARRALDAKR
CCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
VERAVDYLIQAKQISFFGLGASGPVAQDAQHKFFRFNLPVTAYEDVLMQRMVAAATHTGD
HHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCC
VIVIVSYTGRTRELVEIARVARDNGAIVLGITAPDSPLAHECTETLEVITPEDTDVYMPM
EEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHEECCCCCEEECCH
TSRMIHLALIDVLATGVTLRRGEDFLPHLKKIKDSLQATRFPARED
HHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PAFDLIDRIRSRLDELNRSERKVADVILNDPAAATGMSIATLAQAAAVSEPTVNRFCRN
CHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHCCCHHHHHHHHC
FDAKGYPDFKIKLAQSLAGGTPYVSRSVERDDDASSYGDKIFGATIAALDDARRALDAKR
CCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
VERAVDYLIQAKQISFFGLGASGPVAQDAQHKFFRFNLPVTAYEDVLMQRMVAAATHTGD
HHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCC
VIVIVSYTGRTRELVEIARVARDNGAIVLGITAPDSPLAHECTETLEVITPEDTDVYMPM
EEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHEECCCCCEEECCH
TSRMIHLALIDVLATGVTLRRGEDFLPHLKKIKDSLQATRFPARED
HHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]