Click here to switch to the map view.

The map label for this gene is ppa1 [H]

Identifier: 92114402

GI number: 92114402

Start: 2570427

End: 2570957

Strand: Direct

Name: ppa1 [H]

Synonym: Csal_2281

Alternate gene names: 92114402

Gene position: 2570427-2570957 (Clockwise)

Preceding gene: 92114400

Following gene: 92114404

Centisome position: 69.53

GC content: 60.83

Gene sequence:

>531_bases
ATGAGTTTCAAAAACATTCCCGCTGGCAAGGATCTTCCCAACGACGTCTATGTGGCGATCGAGATCCCCGCCAACCACGC
GCCGATCAAGTACGAGATCGACAAGGACATGGATGCGCTGGTCGTCGACCGCTTCATGGCCACGCCGATGTTCTATCCGG
CCAATTACGGTTTCATCAACAACACCCTGGCCGACGACGGCGACCCGCTCGACGCCCTGGTGGTGACCCCTTATCCGGTA
CAGGCCGGCAGCGTGATTCGCGCCCGTCCGGTCGGCGTGCTCAACATGTCCGACGAAGCCGGCGAGGACGCCAAGCTGGT
CTGCGTGCCGCACTCCAAGCTGAGCGCACTTTACGACGACGTGCAGGAAGTCACCGACCTCCCCGAGCTGCTGCGCCAGC
AAATCGCGCATTTCTTCGAGAACTACAAGGATCTCGAGAAAGGCAAGTGGGTGAAGATCGACTCCTGGGATGGCGCCGAC
GCCGCGCGCAAGGCCATCGAAAAAGCCGCGGCCGCCTACACCAAAGCGTAA

Upstream 100 bases:

>100_bases
TCTGCGCCTCTCGTCGATTGGTAAACGCCGGACGCTACTCGTATAATTCCGGGGATTTTCCCCCGCTGGTGTTCAACCTG
CAAACCGCAAGGACTCGACG

Downstream 100 bases:

>100_bases
ACGCCGCGTCTCGCTTCCAGGCAGGCACCACGCCCCGTGTCGCATGCGACACGGGGCGTACTTTTATGCGGCATACGGCC
TGTCCAACACGCCTGCAGGG

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase 1; PPase 1 [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSFKNIPAGKDLPNDVYVAIEIPANHAPIKYEIDKDMDALVVDRFMATPMFYPANYGFINNTLADDGDPLDALVVTPYPV
QAGSVIRARPVGVLNMSDEAGEDAKLVCVPHSKLSALYDDVQEVTDLPELLRQQIAHFFENYKDLEKGKWVKIDSWDGAD
AARKAIEKAAAAYTKA

Sequences:

>Translated_176_residues
MSFKNIPAGKDLPNDVYVAIEIPANHAPIKYEIDKDMDALVVDRFMATPMFYPANYGFINNTLADDGDPLDALVVTPYPV
QAGSVIRARPVGVLNMSDEAGEDAKLVCVPHSKLSALYDDVQEVTDLPELLRQQIAHFFENYKDLEKGKWVKIDSWDGAD
AARKAIEKAAAAYTKA
>Mature_175_residues
SFKNIPAGKDLPNDVYVAIEIPANHAPIKYEIDKDMDALVVDRFMATPMFYPANYGFINNTLADDGDPLDALVVTPYPVQ
AGSVIRARPVGVLNMSDEAGEDAKLVCVPHSKLSALYDDVQEVTDLPELLRQQIAHFFENYKDLEKGKWVKIDSWDGADA
ARKAIEKAAAAYTKA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=166, Percent_Identity=71.6867469879518, Blast_Score=254, Evalue=3e-69,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19416; Mature: 19285

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKNIPAGKDLPNDVYVAIEIPANHAPIKYEIDKDMDALVVDRFMATPMFYPANYGFIN
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
NTLADDGDPLDALVVTPYPVQAGSVIRARPVGVLNMSDEAGEDAKLVCVPHSKLSALYDD
CCCCCCCCCCCEEEECCCCCCCCCEEEECCCEEEECCCCCCCCCEEEEECCHHHHHHHHH
VQEVTDLPELLRQQIAHFFENYKDLEKGKWVKIDSWDGADAARKAIEKAAAAYTKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFKNIPAGKDLPNDVYVAIEIPANHAPIKYEIDKDMDALVVDRFMATPMFYPANYGFIN
CCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
NTLADDGDPLDALVVTPYPVQAGSVIRARPVGVLNMSDEAGEDAKLVCVPHSKLSALYDD
CCCCCCCCCCCEEEECCCCCCCCCEEEECCCEEEECCCCCCCCCEEEEECCHHHHHHHHH
VQEVTDLPELLRQQIAHFFENYKDLEKGKWVKIDSWDGADAARKAIEKAAAAYTKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]