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The map label for this gene is argF

Identifier: 92114252

GI number: 92114252

Start: 2398216

End: 2399133

Strand: Direct

Name: argF

Synonym: Csal_2130

Alternate gene names: 92114252

Gene position: 2398216-2399133 (Clockwise)

Preceding gene: 92114250

Following gene: 92114253

Centisome position: 64.88

GC content: 63.51

Gene sequence:

>918_bases
ATGGCCACACGCCATTTCTTGACCTTACTCGATCTGACACCCGAGGAGCTTAGCCACCTCATTCAGCGTGCGATCACCAT
CAAGAACCGCCTCAAGGCACAAGGGCCGACCTACACGCCCTTCAGCAACCGCACGCTGGCGATGTTTTTCGAGAAGTCCT
CGACGCGTACCCGGGTCTCCTTCGAGACCGCCATGGCGCACTTCGGCGGCCATGCGCTGTTCCTCTCTCCACGGGACACG
CAACTGGGACGCGGCGAACCGATCGGCGACACCGCCCGCGTGCTCGCCGAGATGGTGGACATCGTCATGATTCGCACCTT
CTCGCATGCCGGGCTCGAGGAATATGCCGCCGCCAGCGCGGTTCCCGTGATCAATGCCCTGACGGACGATTACCATCCAT
GCCAGCTGCTGGCCGATGTCATGACCTGGACCGAATGCCGTGGCTCGGTCAAGGGCAAGACGGCGGTGTGGATCGGCGAC
GGCAACAACATGTGCCATTCCTGGATCAACGCGGCACGGCAGTTCGATTTTCGGCTGCGGGTGTGCTGCCCGCCCGGCTA
CGAGCCGGATGCCGACATCGTGGCCGCGGCCGGCGAACGCGTGGAAATCCTTCACGACCCACGGCAAGCGGTGCAGGGCG
CGGATCTCGTCACCACCGACGTCTGGGCCTCGATGGGTCAGGAAGAGGAGCAGGCCCGGCGCGAGCGGGATTTCGCCGGC
TTTCAGGTCACCGAGAAGCTGCTCGATCATGCCGCCGATAACGTGCTGTTCCTGCATTGCCTGCCCGCCCACCGTGGCGA
GGAAATCAGCACCACGTTACTCGACGACCCACGCGCCGCGGTATGGCAGGAAGCCGGCAACCGCCTGCACGCCCAGAAAG
CCCTGATCGAATTCCTGCTGCTGGGCAAAGTCGAATAA

Upstream 100 bases:

>100_bases
CGAGGCCGGGTGCGCGAGGACGAGCCCCGATCGCGGCCCGTCGCGCCCCGTTTCTTTTCGTTGGCGAGTGCCGTCGATTT
CATCTGCAAGGAGCGTCGCC

Downstream 100 bases:

>100_bases
CGTCAAGACCGAGACCGGCCAGAACGATGCCCGCCATCTTTCTGGCAACAATCTGGCCGGTTCAAGCCCTCCACAAGCGC
CGTCTTCGGCCTGTAGTCGG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MATRHFLTLLDLTPEELSHLIQRAITIKNRLKAQGPTYTPFSNRTLAMFFEKSSTRTRVSFETAMAHFGGHALFLSPRDT
QLGRGEPIGDTARVLAEMVDIVMIRTFSHAGLEEYAAASAVPVINALTDDYHPCQLLADVMTWTECRGSVKGKTAVWIGD
GNNMCHSWINAARQFDFRLRVCCPPGYEPDADIVAAAGERVEILHDPRQAVQGADLVTTDVWASMGQEEEQARRERDFAG
FQVTEKLLDHAADNVLFLHCLPAHRGEEISTTLLDDPRAAVWQEAGNRLHAQKALIEFLLLGKVE

Sequences:

>Translated_305_residues
MATRHFLTLLDLTPEELSHLIQRAITIKNRLKAQGPTYTPFSNRTLAMFFEKSSTRTRVSFETAMAHFGGHALFLSPRDT
QLGRGEPIGDTARVLAEMVDIVMIRTFSHAGLEEYAAASAVPVINALTDDYHPCQLLADVMTWTECRGSVKGKTAVWIGD
GNNMCHSWINAARQFDFRLRVCCPPGYEPDADIVAAAGERVEILHDPRQAVQGADLVTTDVWASMGQEEEQARRERDFAG
FQVTEKLLDHAADNVLFLHCLPAHRGEEISTTLLDDPRAAVWQEAGNRLHAQKALIEFLLLGKVE
>Mature_304_residues
ATRHFLTLLDLTPEELSHLIQRAITIKNRLKAQGPTYTPFSNRTLAMFFEKSSTRTRVSFETAMAHFGGHALFLSPRDTQ
LGRGEPIGDTARVLAEMVDIVMIRTFSHAGLEEYAAASAVPVINALTDDYHPCQLLADVMTWTECRGSVKGKTAVWIGDG
NNMCHSWINAARQFDFRLRVCCPPGYEPDADIVAAAGERVEILHDPRQAVQGADLVTTDVWASMGQEEEQARRERDFAGF
QVTEKLLDHAADNVLFLHCLPAHRGEEISTTLLDDPRAAVWQEAGNRLHAQKALIEFLLLGKVE

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=292, Percent_Identity=42.1232876712329, Blast_Score=243, Evalue=1e-64,
Organism=Homo sapiens, GI18105007, Length=308, Percent_Identity=27.9220779220779, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=35.8895705521472, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1786469, Length=326, Percent_Identity=35.5828220858896, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI2367364, Length=309, Percent_Identity=28.8025889967638, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994908, Length=352, Percent_Identity=24.1477272727273, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=323, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=321, Percent_Identity=34.5794392523364, Blast_Score=201, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6322331, Length=265, Percent_Identity=28.6792452830189, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24642586, Length=316, Percent_Identity=25.9493670886076, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): OTC_CHRSD (Q1QVM7)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574180.1
- ProteinModelPortal:   Q1QVM7
- SMR:   Q1QVM7
- STRING:   Q1QVM7
- GeneID:   4026466
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2130
- NMPDR:   fig|290398.4.peg.2264
- eggNOG:   COG0078
- HOGENOM:   HBG579429
- OMA:   CVVTDTW
- ProtClustDB:   PRK00779
- BioCyc:   CSAL290398:CSAL_2130-MONOMER
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 33953; Mature: 33822

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 105-105 BINDING 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRHFLTLLDLTPEELSHLIQRAITIKNRLKAQGPTYTPFSNRTLAMFFEKSSTRTRVS
CCCHHEEHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEH
FETAMAHFGGHALFLSPRDTQLGRGEPIGDTARVLAEMVDIVMIRTFSHAGLEEYAAASA
HHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VPVINALTDDYHPCQLLADVMTWTECRGSVKGKTAVWIGDGNNMCHSWINAARQFDFRLR
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEE
VCCPPGYEPDADIVAAAGERVEILHDPRQAVQGADLVTTDVWASMGQEEEQARRERDFAG
EECCCCCCCCCCHHHHCCCEEEEHCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCC
FQVTEKLLDHAADNVLFLHCLPAHRGEEISTTLLDDPRAAVWQEAGNRLHAQKALIEFLL
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHH
LGKVE
HCCCC
>Mature Secondary Structure 
ATRHFLTLLDLTPEELSHLIQRAITIKNRLKAQGPTYTPFSNRTLAMFFEKSSTRTRVS
CCHHEEHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEH
FETAMAHFGGHALFLSPRDTQLGRGEPIGDTARVLAEMVDIVMIRTFSHAGLEEYAAASA
HHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VPVINALTDDYHPCQLLADVMTWTECRGSVKGKTAVWIGDGNNMCHSWINAARQFDFRLR
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEE
VCCPPGYEPDADIVAAAGERVEILHDPRQAVQGADLVTTDVWASMGQEEEQARRERDFAG
EECCCCCCCCCCHHHHCCCEEEEHCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCC
FQVTEKLLDHAADNVLFLHCLPAHRGEEISTTLLDDPRAAVWQEAGNRLHAQKALIEFLL
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHH
LGKVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA