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The map label for this gene is atoS [H]

Identifier: 92114208

GI number: 92114208

Start: 2354130

End: 2356229

Strand: Direct

Name: atoS [H]

Synonym: Csal_2086

Alternate gene names: 92114208

Gene position: 2354130-2356229 (Clockwise)

Preceding gene: 92114207

Following gene: 92114209

Centisome position: 63.68

GC content: 67.81

Gene sequence:

>2100_bases
ATGAACGGCCTGCGCCGCTGGTTGCGCGCCTCGATCCGTCGCCGCCTGCTATGGCTGGCCTTCGCGCCGCTGGTCCTGCT
GGCATTGGCGCTCGCCGGGCTCACCGCCTACTGGACCTCCACGTACAACGACCGCCAGCTGTACATGAAAGTTCGTGCCG
ACCTGGCCGTCGCCTCACGCGTGCTAGACAGCTTGAGTCAGCAACAGCAGGCACGCCTGGAAGAACTCGCGCGCAGTCAT
GCCCTGGCCTCGTCGCTGCAAGGGGATGGCACGCAATCGCTCGATGCCCTGCTCGATGAAACCCAGCGTGCGATGCAACT
GGACTGGCTCCGCGTGGTTTCCCCCGACATGCTCGATGGCGACCCGCAGTTGCAACGCCGCCTGCAACCGCCCGATGACG
GCAGCGGCATTTCCGGTCTGGACGTGCTCAGTGCCTCACGGCTCGAGACACTGGCACCGGGTCTGGCCGAGCGCGCACGC
CTGCCGCTGCGCGAGACTCCGCAGGCAGTCCCGAGCGAACGACGGCATGAAACGCGCGGCATGGTGCTGCGCACGCTGAC
GCCCTTGCGTGACGCCCAGGGCCATCTGCGCCTGCTGCTGGACGGCGGCCGCCTGCTCAATGGCGACGCCGGGCCGGTCG
ACGAGATTCGCGACCTGGTCTACGGACCCGGCACGCTGCCCGAGGGCACCACGGGCAGCGTGACCCTGTTTCTCGACGAT
GTGCGCATCGCTACCAACGTGCGCCTGGCCAACGGCGAGCGCGCCCTGGGCACTCGCGTCTCGCAGCCCGTCAGCGAGCA
GGTGCTGGCGCGCGGCGAACGCTTCATCGACAACGCCTTCGTGGTCAGCGGGTGGTACGTGGCGGCCTATGCGCCCCTTG
CCTCGCTGACCGGTCAACGCATCGGCATGATCTACGCCGGCTTCCCCCTGACGCCGTACCAGCGTCTGTACCGCGAAACG
CTGCTCCAGATCGGCGGCGTCCTGGCCGTGATCATGCTGATCTCCGGCTTGATGGTGATTCGCGGCGTGGATACCCTCGC
CAGCCCCGTGCGCCGGATGCACCGCGTGATTCACGGCATCCGTGAAGGCCGTCAGTTGCGTATCGGGCATCTCGACAGCC
AGGACGAACTGGCCGAGCTGGCGCAGGAATTCGATGCCATGCTCGACCGGCTGGACGAACACCAGCATGCCCTGGAACGC
GCCGCCCAGACGCTCGAGCGTCGCGTTCAGAGCCGCACGCACTCGCTGACCGAAAAAACCCGCGCGCTCGAGGAGCACGT
GGCCTTGCTCAAGCAGGCACGGGCCAGCCTCATGACCCAGGAAAAGCTCGCGGCCCTGGGCGAATTGACCGCCGGCATCG
CGCACGAGATCAACAATCCCGCGGCGGTGATACTCGGGCACGTGGAACTCATTGCCGATACGCTGGGGCCCGACGTGGCC
CCGGTACGCGACGAGGTGGACACCATCATCGCGCAGGTCGAACGCATCCGCGCGCTGATCGACAATCTGCTGCAATACTC
GCGCGCCGGCGGCGGTCAGGAACCGGCGTTCCGCGCCGAGGACATCAATGCCATCGCCGCGGACACCGAAGTCCTCGTCC
GCCACGCGCTCGACAAGCATGGTCACCGGCTGGTGAGCGCCCTGCATGCCACGCGGCCGGTCGAATGTCATCGTGGTCAG
CTGCAGCAAGTGTTGATCAACCTGCTGCTCAACGCCGCCCAGGCCAGCACCGCGCCGGTGACCATTCACCTCGTCACGCG
CGACAGCGTGCGCGAGGTGCCGGGACGCGGCGACCTCGACGGCGTGGAAATCCGCGTCGCCGATCCGGGACCGGGCATGT
CCAAGGCAGTCCGCCAGCGCATCTTCGACCCGTTCTTCACCACCCGCGAGGCCGGCTCCGGCCTGGGCCTGGCGATCAGT
GCCGGCATCGTGCGTCGCAGCGGGGGAGACATAGGTGTCGCCTCGAGGCCGGGCCGCGGCACGATCTTCCATGTCTGGCT
GCCATGCCGGGCAGCACCCAGCGGCGCAGAGGAGGCCACGACCCGCAAGTTGCTCGACTCTCTCAGCGATGCCACCGCGC
CGTCGTCACGCGGCAGTTAA

Upstream 100 bases:

>100_bases
TGGACGCGCACGCCAACAACAAGTCCAGTGCCGCTCGCGCGCTCGGCGTGTCGCGCAAGACGCTCGATCGCAAGCTCACC
GCCTGGCAAGACCTCGACGC

Downstream 100 bases:

>100_bases
GCTTGGCGCGCCGACCCGCTATCATGGCCCGCAACGTCTCACAGCATGCCAAGGAACCTTCATGAGTGGATTCGACGTCG
GTGCACGTCTCAAGCAGTTG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MNGLRRWLRASIRRRLLWLAFAPLVLLALALAGLTAYWTSTYNDRQLYMKVRADLAVASRVLDSLSQQQQARLEELARSH
ALASSLQGDGTQSLDALLDETQRAMQLDWLRVVSPDMLDGDPQLQRRLQPPDDGSGISGLDVLSASRLETLAPGLAERAR
LPLRETPQAVPSERRHETRGMVLRTLTPLRDAQGHLRLLLDGGRLLNGDAGPVDEIRDLVYGPGTLPEGTTGSVTLFLDD
VRIATNVRLANGERALGTRVSQPVSEQVLARGERFIDNAFVVSGWYVAAYAPLASLTGQRIGMIYAGFPLTPYQRLYRET
LLQIGGVLAVIMLISGLMVIRGVDTLASPVRRMHRVIHGIREGRQLRIGHLDSQDELAELAQEFDAMLDRLDEHQHALER
AAQTLERRVQSRTHSLTEKTRALEEHVALLKQARASLMTQEKLAALGELTAGIAHEINNPAAVILGHVELIADTLGPDVA
PVRDEVDTIIAQVERIRALIDNLLQYSRAGGGQEPAFRAEDINAIAADTEVLVRHALDKHGHRLVSALHATRPVECHRGQ
LQQVLINLLLNAAQASTAPVTIHLVTRDSVREVPGRGDLDGVEIRVADPGPGMSKAVRQRIFDPFFTTREAGSGLGLAIS
AGIVRRSGGDIGVASRPGRGTIFHVWLPCRAAPSGAEEATTRKLLDSLSDATAPSSRGS

Sequences:

>Translated_699_residues
MNGLRRWLRASIRRRLLWLAFAPLVLLALALAGLTAYWTSTYNDRQLYMKVRADLAVASRVLDSLSQQQQARLEELARSH
ALASSLQGDGTQSLDALLDETQRAMQLDWLRVVSPDMLDGDPQLQRRLQPPDDGSGISGLDVLSASRLETLAPGLAERAR
LPLRETPQAVPSERRHETRGMVLRTLTPLRDAQGHLRLLLDGGRLLNGDAGPVDEIRDLVYGPGTLPEGTTGSVTLFLDD
VRIATNVRLANGERALGTRVSQPVSEQVLARGERFIDNAFVVSGWYVAAYAPLASLTGQRIGMIYAGFPLTPYQRLYRET
LLQIGGVLAVIMLISGLMVIRGVDTLASPVRRMHRVIHGIREGRQLRIGHLDSQDELAELAQEFDAMLDRLDEHQHALER
AAQTLERRVQSRTHSLTEKTRALEEHVALLKQARASLMTQEKLAALGELTAGIAHEINNPAAVILGHVELIADTLGPDVA
PVRDEVDTIIAQVERIRALIDNLLQYSRAGGGQEPAFRAEDINAIAADTEVLVRHALDKHGHRLVSALHATRPVECHRGQ
LQQVLINLLLNAAQASTAPVTIHLVTRDSVREVPGRGDLDGVEIRVADPGPGMSKAVRQRIFDPFFTTREAGSGLGLAIS
AGIVRRSGGDIGVASRPGRGTIFHVWLPCRAAPSGAEEATTRKLLDSLSDATAPSSRGS
>Mature_699_residues
MNGLRRWLRASIRRRLLWLAFAPLVLLALALAGLTAYWTSTYNDRQLYMKVRADLAVASRVLDSLSQQQQARLEELARSH
ALASSLQGDGTQSLDALLDETQRAMQLDWLRVVSPDMLDGDPQLQRRLQPPDDGSGISGLDVLSASRLETLAPGLAERAR
LPLRETPQAVPSERRHETRGMVLRTLTPLRDAQGHLRLLLDGGRLLNGDAGPVDEIRDLVYGPGTLPEGTTGSVTLFLDD
VRIATNVRLANGERALGTRVSQPVSEQVLARGERFIDNAFVVSGWYVAAYAPLASLTGQRIGMIYAGFPLTPYQRLYRET
LLQIGGVLAVIMLISGLMVIRGVDTLASPVRRMHRVIHGIREGRQLRIGHLDSQDELAELAQEFDAMLDRLDEHQHALER
AAQTLERRVQSRTHSLTEKTRALEEHVALLKQARASLMTQEKLAALGELTAGIAHEINNPAAVILGHVELIADTLGPDVA
PVRDEVDTIIAQVERIRALIDNLLQYSRAGGGQEPAFRAEDINAIAADTEVLVRHALDKHGHRLVSALHATRPVECHRGQ
LQQVLINLLLNAAQASTAPVTIHLVTRDSVREVPGRGDLDGVEIRVADPGPGMSKAVRQRIFDPFFTTREAGSGLGLAIS
AGIVRRSGGDIGVASRPGRGTIFHVWLPCRAAPSGAEEATTRKLLDSLSDATAPSSRGS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=34.136546184739, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1790300, Length=274, Percent_Identity=31.7518248175182, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=447, Percent_Identity=23.9373601789709, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081816, Length=365, Percent_Identity=27.3972602739726, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=29.7397769516729, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=281, Percent_Identity=27.7580071174377, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788393, Length=332, Percent_Identity=26.2048192771084, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=24.1803278688525, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76208; Mature: 76208

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLRRWLRASIRRRLLWLAFAPLVLLALALAGLTAYWTSTYNDRQLYMKVRADLAVASR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VLDSLSQQQQARLEELARSHALASSLQGDGTQSLDALLDETQRAMQLDWLRVVSPDMLDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DPQLQRRLQPPDDGSGISGLDVLSASRLETLAPGLAERARLPLRETPQAVPSERRHETRG
CHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
MVLRTLTPLRDAQGHLRLLLDGGRLLNGDAGPVDEIRDLVYGPGTLPEGTTGSVTLFLDD
HHHHHHHHHHCCCCCEEEEEECCEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEC
VRIATNVRLANGERALGTRVSQPVSEQVLARGERFIDNAFVVSGWYVAAYAPLASLTGQR
EEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCC
IGMIYAGFPLTPYQRLYRETLLQIGGVLAVIMLISGLMVIRGVDTLASPVRRMHRVIHGI
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGRQLRIGHLDSQDELAELAQEFDAMLDRLDEHQHALERAAQTLERRVQSRTHSLTEKT
HCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALEEHVALLKQARASLMTQEKLAALGELTAGIAHEINNPAAVILGHVELIADTLGPDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PVRDEVDTIIAQVERIRALIDNLLQYSRAGGGQEPAFRAEDINAIAADTEVLVRHALDKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHH
GHRLVSALHATRPVECHRGQLQQVLINLLLNAAQASTAPVTIHLVTRDSVREVPGRGDLD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHCCCCCCCC
GVEIRVADPGPGMSKAVRQRIFDPFFTTREAGSGLGLAISAGIVRRSGGDIGVASRPGRG
CEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCCCCCCCC
TIFHVWLPCRAAPSGAEEATTRKLLDSLSDATAPSSRGS
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNGLRRWLRASIRRRLLWLAFAPLVLLALALAGLTAYWTSTYNDRQLYMKVRADLAVASR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VLDSLSQQQQARLEELARSHALASSLQGDGTQSLDALLDETQRAMQLDWLRVVSPDMLDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DPQLQRRLQPPDDGSGISGLDVLSASRLETLAPGLAERARLPLRETPQAVPSERRHETRG
CHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
MVLRTLTPLRDAQGHLRLLLDGGRLLNGDAGPVDEIRDLVYGPGTLPEGTTGSVTLFLDD
HHHHHHHHHHCCCCCEEEEEECCEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEC
VRIATNVRLANGERALGTRVSQPVSEQVLARGERFIDNAFVVSGWYVAAYAPLASLTGQR
EEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCC
IGMIYAGFPLTPYQRLYRETLLQIGGVLAVIMLISGLMVIRGVDTLASPVRRMHRVIHGI
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGRQLRIGHLDSQDELAELAQEFDAMLDRLDEHQHALERAAQTLERRVQSRTHSLTEKT
HCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALEEHVALLKQARASLMTQEKLAALGELTAGIAHEINNPAAVILGHVELIADTLGPDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PVRDEVDTIIAQVERIRALIDNLLQYSRAGGGQEPAFRAEDINAIAADTEVLVRHALDKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHH
GHRLVSALHATRPVECHRGQLQQVLINLLLNAAQASTAPVTIHLVTRDSVREVPGRGDLD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHCCCCCCCC
GVEIRVADPGPGMSKAVRQRIFDPFFTTREAGSGLGLAISAGIVRRSGGDIGVASRPGRG
CEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCCCCCCCC
TIFHVWLPCRAAPSGAEEATTRKLLDSLSDATAPSSRGS
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]