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The map label for this gene is csiR [H]

Identifier: 92114119

GI number: 92114119

Start: 2255264

End: 2255944

Strand: Direct

Name: csiR [H]

Synonym: Csal_1997

Alternate gene names: 92114119

Gene position: 2255264-2255944 (Clockwise)

Preceding gene: 92114116

Following gene: 92114124

Centisome position: 61.01

GC content: 65.79

Gene sequence:

>681_bases
ATGACCAGCGCCAGTCCGCGCCCCAATCTCGCCATCACTGCCTACCGACAACTCAAGCGCGATATCATTCGCGGCGTCTA
CGCGCCCGGCGAAAAACTCCGCATGAGCCATCTCAAGGAACGCTACGCGCTTGGCGTTGGCCCGATGCGCGAGGCGTTGT
CGCAACTGGTCGGGGAGCGCCTGGTCACGGCGGTCAGCCAGCGGGGCTATCGCGTCGCCGAGATGTCGATCGAAGAGCTC
GAGTCACTCTACGATGCCCGTGCGGAACTGGAGGGACTGGTGCTGGAACTGGCCATCGCGCGCGGCGGCGACGACTGGGA
AGCCGGTATCGTCGCCAAGGCGCATGCCCTGGCCAAGGTGGCCGAGGTACACAGTGCCGAGGACATGCTCGATGTGTGGG
ACACGCGCCACCAGGCGTTTCATAGCGCCATCGCGGCCGGCTGCGACTCGCCGCACCTGTTGCAGGCACGCACCTGGTTA
TTCGATCAGGCCGAGCGCTATCGTCACCTGTGGCTGTGCCAGACGGTGTTCTCCGCGGAGGCACTGGACGCCAAGCGCCG
GGAGCACGCCGCACTCACCGACGCCATTCTCGCCCGCGACACGCCCACCGCCCGCGCGATGATGCGCGAACATCTGATGT
CACCGGTGCCGATCATCAAGGAGGTCATGCAGCAGCGGTGA

Upstream 100 bases:

>100_bases
ACGTCAAAATTAAACCGAAGCCTCGCACCTTATCCCACAACGTCTCCCCGGTCGTGGCCTTGTCCGGTATCATGCGAGGG
CATTTTCAGGGAATCGCGTC

Downstream 100 bases:

>100_bases
ACGACCAGGCACGATCGCAACGCGGCAAGGCATCGCGCCGGTGGGCGAACATCAACACGCTGCGCCCGTCGAGCCAGGTA
TCCAGGCGCTCGGCGATGAT

Product: DNA-binding transcriptional regulator CsiR

Products: NA

Alternate protein names: Carbon starvation induced regulator [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTSASPRPNLAITAYRQLKRDIIRGVYAPGEKLRMSHLKERYALGVGPMREALSQLVGERLVTAVSQRGYRVAEMSIEEL
ESLYDARAELEGLVLELAIARGGDDWEAGIVAKAHALAKVAEVHSAEDMLDVWDTRHQAFHSAIAAGCDSPHLLQARTWL
FDQAERYRHLWLCQTVFSAEALDAKRREHAALTDAILARDTPTARAMMREHLMSPVPIIKEVMQQR

Sequences:

>Translated_226_residues
MTSASPRPNLAITAYRQLKRDIIRGVYAPGEKLRMSHLKERYALGVGPMREALSQLVGERLVTAVSQRGYRVAEMSIEEL
ESLYDARAELEGLVLELAIARGGDDWEAGIVAKAHALAKVAEVHSAEDMLDVWDTRHQAFHSAIAAGCDSPHLLQARTWL
FDQAERYRHLWLCQTVFSAEALDAKRREHAALTDAILARDTPTARAMMREHLMSPVPIIKEVMQQR
>Mature_225_residues
TSASPRPNLAITAYRQLKRDIIRGVYAPGEKLRMSHLKERYALGVGPMREALSQLVGERLVTAVSQRGYRVAEMSIEELE
SLYDARAELEGLVLELAIARGGDDWEAGIVAKAHALAKVAEVHSAEDMLDVWDTRHQAFHSAIAAGCDSPHLLQARTWLF
DQAERYRHLWLCQTVFSAEALDAKRREHAALTDAILARDTPTARAMMREHLMSPVPIIKEVMQQR

Specific function: Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082149, Length=213, Percent_Identity=59.6244131455399, Blast_Score=263, Evalue=9e-72,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25364; Mature: 25233

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSASPRPNLAITAYRQLKRDIIRGVYAPGEKLRMSHLKERYALGVGPMREALSQLVGER
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LVTAVSQRGYRVAEMSIEELESLYDARAELEGLVLELAIARGGDDWEAGIVAKAHALAKV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AEVHSAEDMLDVWDTRHQAFHSAIAAGCDSPHLLQARTWLFDQAERYRHLWLCQTVFSAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDAKRREHAALTDAILARDTPTARAMMREHLMSPVPIIKEVMQQR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TSASPRPNLAITAYRQLKRDIIRGVYAPGEKLRMSHLKERYALGVGPMREALSQLVGER
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LVTAVSQRGYRVAEMSIEELESLYDARAELEGLVLELAIARGGDDWEAGIVAKAHALAKV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AEVHSAEDMLDVWDTRHQAFHSAIAAGCDSPHLLQARTWLFDQAERYRHLWLCQTVFSAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDAKRREHAALTDAILARDTPTARAMMREHLMSPVPIIKEVMQQR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8297211; 7984428 [H]