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The map label for this gene is ychM [C]

Identifier: 92114116

GI number: 92114116

Start: 2251033

End: 2252784

Strand: Direct

Name: ychM [C]

Synonym: Csal_1994

Alternate gene names: 92114116

Gene position: 2251033-2252784 (Clockwise)

Preceding gene: 92114115

Following gene: 92114119

Centisome position: 60.89

GC content: 65.98

Gene sequence:

>1752_bases
ATGCTCAAGCGCTACCTGCCCATTCTCGAGTGGCTGCCGCGTTACGATCGTCAGACACTCTCGCAAGACCTGTTCGCCGC
CGTCATCGTGACGCTCATGGTCATTCCCCAGGCCCTGGCATATGCCCTGCTCGCGGGACTGCCGGCGGTAACCGGTCTGT
ATGCCAGCATGCTGCCGCTGGTGGCCTACACCGTCTTCGGCACCAGCCGCACCCTGGCGGTCGGGCCGATGGCGATCGTC
TCGCTGATGACCGCCGCGGCGCTGTCCGGCATCGTCGCCACGGGAACCGTCGCCTACAGCGAAGCCGCAGCAACGCTGGC
GTTTCTGTCCGGCGTCATGCTGATGCTGATGGGCATCTTTCGCTTGGGGTTCTTCGCCAACTTCCTGAGTCACCCCGTGA
TCTCGGGGTTGCTCAGCGCCTCCGGCGTGCTGATCGCCACCAGCCAATTGGGCAACCTGCTGGGCATTTCGATGTCCGGC
TTCACGCTGATCGACCAGCTGGCCGGGCTGGCCCTGCACTGGCGGGACTTCAGCATGCCCACGGCACTGATCGGCCTGGG
ATCGCTGGGTTTCTTGATGGTGATGCGTCGTGCGGGGCCGGTACTCAAGAGCTGGGGCCTCTCGGCCACGCTCAGCGGCT
TCATCGCCAAGGCCGGGCCGATCATCGCCGTCGTCGTCTCCACCCTGCTGGTATGGGCGTTCGATCTGGAAGCGCACGGC
GTGGCCGTGGTCGGCGAGATTCCCCGTCATCTGCCGCCGATCGCATTGCCCTCGCTGGATCCGAGCCTGCTGAGCACCCT
CTGGATGCCGGCGCTCCTGATCAGCCTGGTGGGCTTCATCGAATCAGTCTCGCTGGCGCAGATGCTCGCCGCCAAGCGCC
GACAGCGCATCTCGCCGGACCAGGAGCTGTTCGCGCTGGGAGGCAGCAACCTCGCCGCCGCGTTGAGCAGCAGCATGCCG
GTGACAGGCAGCCTGTCACGCACGGTGATCAACTTCGATGCCGGGGCACGCACGCCGGCGGCAGGCAGCTTCGCCGCGCT
GGGCGTGGCGCTGGTGACGCTCTATCTCACGCCGCTGATCCACTTTCTGCCCATCGCCACGCTGGCCGCCAGCATCATCG
TCTCGACCTTCACGCTGCTCGACGCGCGGGGCCTGAAGCGCACCTGGCGCTACTCGAAGCGTGACTTCGCCGCCATGCTG
GCCACCATCGTGCTGACGTTCGTGGTCGGGGTCGAGGCGGGCGTCATGGCCGGGGTCGGCTTGTCGCTGGCACTGTTCCT
GTACCGCACCAGCCGGCCGCACAGCGCGCTGGTGGGTCGCGTGCCCGGCACCGAGCACTTCCGCAACGTGGAACGCTACG
CCACCGAGAACGACCCGCACGTGGCCTTGCTGCGGGTCGACGAAAGCCTGTACTTCGCCAATGCGCGTTATCTGGAAGAT
ACCGTCTATGCCATGGTCGCCGAGCGTCCCGCGCTCAAGCACGTGGTCTTGATCGGCTCGGCGGTGAACCTGATCGACGC
CTCGGCGCTGGAAAGCCTCGAAGCCATCAATGCTCGCCTGGAGGACTCCCGAGTCAAGCTCCACCTGGCCGAGGTGAAGG
GACCGGTCATGGACCAGCTCAAGCAGAGCGACTTCCTCGAGCATCTCACCGGCGAGGTGTTTCTCAGCACCTACCACGCC
TGGGAAGCCCTGCGCGAGGAAGACACCGTAGTGACGCCGCTGGATGGCGACGACGCCTCCCGCCAGGATTAA

Upstream 100 bases:

>100_bases
GCATCGTGACGCTTTCTTGCGCGCTTTTTCGCGCATGGAACGGTTTCGATCACATGAACACTCGCTTACATCAATATTCG
CTCACCTAAACAGGACCCGG

Downstream 100 bases:

>100_bases
CGTCGACTCTCCAGGCGAGGCTAGGCCTCGACCTGGGCCCTCACCTGCTCGACGATATGCGCACCGATGGGAATCGCCGA
GGTGGCGGCGGGCGACGGCG

Product: sulfate permease

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MLKRYLPILEWLPRYDRQTLSQDLFAAVIVTLMVIPQALAYALLAGLPAVTGLYASMLPLVAYTVFGTSRTLAVGPMAIV
SLMTAAALSGIVATGTVAYSEAAATLAFLSGVMLMLMGIFRLGFFANFLSHPVISGLLSASGVLIATSQLGNLLGISMSG
FTLIDQLAGLALHWRDFSMPTALIGLGSLGFLMVMRRAGPVLKSWGLSATLSGFIAKAGPIIAVVVSTLLVWAFDLEAHG
VAVVGEIPRHLPPIALPSLDPSLLSTLWMPALLISLVGFIESVSLAQMLAAKRRQRISPDQELFALGGSNLAAALSSSMP
VTGSLSRTVINFDAGARTPAAGSFAALGVALVTLYLTPLIHFLPIATLAASIIVSTFTLLDARGLKRTWRYSKRDFAAML
ATIVLTFVVGVEAGVMAGVGLSLALFLYRTSRPHSALVGRVPGTEHFRNVERYATENDPHVALLRVDESLYFANARYLED
TVYAMVAERPALKHVVLIGSAVNLIDASALESLEAINARLEDSRVKLHLAEVKGPVMDQLKQSDFLEHLTGEVFLSTYHA
WEALREEDTVVTPLDGDDASRQD

Sequences:

>Translated_583_residues
MLKRYLPILEWLPRYDRQTLSQDLFAAVIVTLMVIPQALAYALLAGLPAVTGLYASMLPLVAYTVFGTSRTLAVGPMAIV
SLMTAAALSGIVATGTVAYSEAAATLAFLSGVMLMLMGIFRLGFFANFLSHPVISGLLSASGVLIATSQLGNLLGISMSG
FTLIDQLAGLALHWRDFSMPTALIGLGSLGFLMVMRRAGPVLKSWGLSATLSGFIAKAGPIIAVVVSTLLVWAFDLEAHG
VAVVGEIPRHLPPIALPSLDPSLLSTLWMPALLISLVGFIESVSLAQMLAAKRRQRISPDQELFALGGSNLAAALSSSMP
VTGSLSRTVINFDAGARTPAAGSFAALGVALVTLYLTPLIHFLPIATLAASIIVSTFTLLDARGLKRTWRYSKRDFAAML
ATIVLTFVVGVEAGVMAGVGLSLALFLYRTSRPHSALVGRVPGTEHFRNVERYATENDPHVALLRVDESLYFANARYLED
TVYAMVAERPALKHVVLIGSAVNLIDASALESLEAINARLEDSRVKLHLAEVKGPVMDQLKQSDFLEHLTGEVFLSTYHA
WEALREEDTVVTPLDGDDASRQD
>Mature_583_residues
MLKRYLPILEWLPRYDRQTLSQDLFAAVIVTLMVIPQALAYALLAGLPAVTGLYASMLPLVAYTVFGTSRTLAVGPMAIV
SLMTAAALSGIVATGTVAYSEAAATLAFLSGVMLMLMGIFRLGFFANFLSHPVISGLLSASGVLIATSQLGNLLGISMSG
FTLIDQLAGLALHWRDFSMPTALIGLGSLGFLMVMRRAGPVLKSWGLSATLSGFIAKAGPIIAVVVSTLLVWAFDLEAHG
VAVVGEIPRHLPPIALPSLDPSLLSTLWMPALLISLVGFIESVSLAQMLAAKRRQRISPDQELFALGGSNLAAALSSSMP
VTGSLSRTVINFDAGARTPAAGSFAALGVALVTLYLTPLIHFLPIATLAASIIVSTFTLLDARGLKRTWRYSKRDFAAML
ATIVLTFVVGVEAGVMAGVGLSLALFLYRTSRPHSALVGRVPGTEHFRNVERYATENDPHVALLRVDESLYFANARYLED
TVYAMVAERPALKHVVLIGSAVNLIDASALESLEAINARLEDSRVKLHLAEVKGPVMDQLKQSDFLEHLTGEVFLSTYHA
WEALREEDTVVTPLDGDDASRQD

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI39752683, Length=566, Percent_Identity=29.1519434628975, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI45827800, Length=566, Percent_Identity=29.1519434628975, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI94721253, Length=499, Percent_Identity=32.4649298597194, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI94721259, Length=499, Percent_Identity=32.4649298597194, Blast_Score=212, Evalue=9e-55,
Organism=Homo sapiens, GI94721255, Length=499, Percent_Identity=32.4649298597194, Blast_Score=212, Evalue=1e-54,
Organism=Homo sapiens, GI94721257, Length=499, Percent_Identity=32.4649298597194, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI262206105, Length=591, Percent_Identity=30.7952622673435, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI262206075, Length=591, Percent_Identity=30.7952622673435, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI262206069, Length=591, Percent_Identity=30.7952622673435, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI262206063, Length=591, Percent_Identity=30.7952622673435, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI269784651, Length=565, Percent_Identity=27.6106194690265, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI45827802, Length=463, Percent_Identity=30.8855291576674, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI100913030, Length=651, Percent_Identity=24.7311827956989, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI20336282, Length=535, Percent_Identity=25.7943925233645, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI16306483, Length=535, Percent_Identity=25.7943925233645, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI4505697, Length=518, Percent_Identity=26.8339768339768, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI47131207, Length=651, Percent_Identity=27.8033794162826, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI20336272, Length=651, Percent_Identity=27.8033794162826, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI4557535, Length=515, Percent_Identity=26.7961165048544, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI16418413, Length=521, Percent_Identity=27.063339731286, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI217272867, Length=521, Percent_Identity=27.063339731286, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI65506789, Length=571, Percent_Identity=27.84588441331, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI16418457, Length=514, Percent_Identity=25.6809338521401, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI301601599, Length=514, Percent_Identity=25.6809338521401, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI45827804, Length=268, Percent_Identity=30.2238805970149, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI301601602, Length=229, Percent_Identity=27.9475982532751, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87081859, Length=544, Percent_Identity=25.1838235294118, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI86564196, Length=621, Percent_Identity=25.9259259259259, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17551690, Length=565, Percent_Identity=27.0796460176991, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17562578, Length=644, Percent_Identity=28.416149068323, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17566848, Length=553, Percent_Identity=30.0180831826401, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI86565215, Length=563, Percent_Identity=27.886323268206, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI86564876, Length=584, Percent_Identity=25.6849315068493, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI193203292, Length=581, Percent_Identity=23.5800344234079, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI86565213, Length=269, Percent_Identity=29.368029739777, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI86565209, Length=237, Percent_Identity=27.8481012658228, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI86565211, Length=247, Percent_Identity=27.1255060728745, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323121, Length=509, Percent_Identity=28.6836935166994, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319771, Length=480, Percent_Identity=27.9166666666667, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6325260, Length=595, Percent_Identity=24.0336134453782, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24649801, Length=605, Percent_Identity=30.0826446280992, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI19922482, Length=528, Percent_Identity=28.030303030303, Blast_Score=219, Evalue=5e-57,
Organism=Drosophila melanogaster, GI85815873, Length=535, Percent_Identity=29.9065420560748, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24651449, Length=513, Percent_Identity=27.4853801169591, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24663084, Length=574, Percent_Identity=28.5714285714286, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI21357695, Length=574, Percent_Identity=28.5714285714286, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI21358633, Length=546, Percent_Identity=28.021978021978, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21355087, Length=583, Percent_Identity=26.0720411663808, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24647160, Length=583, Percent_Identity=26.0720411663808, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI21358229, Length=511, Percent_Identity=28.1800391389432, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24666186, Length=553, Percent_Identity=27.6672694394213, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 62272; Mature: 62272

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]