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The map label for this gene is moeA [H]

Identifier: 92114043

GI number: 92114043

Start: 2180538

End: 2181728

Strand: Direct

Name: moeA [H]

Synonym: Csal_1920

Alternate gene names: 92114043

Gene position: 2180538-2181728 (Clockwise)

Preceding gene: 92114042

Following gene: 92114049

Centisome position: 58.99

GC content: 69.1

Gene sequence:

>1191_bases
ATGGCTGAGCTGCAAAGCGTCGAACGTGCGCTGTCGGCACTGCTGGACGGCGTGAGCCCGAGCGAGCCCGAATGGATCGA
CTGCACGCAAGCCGCCGGCCGCGTCCTGGCGGAAACCGTCACCGCGCGTCTCGACGTGCCGCCGGCCGATAACAGCGCCA
TGGACGGCTATGCGCTGCGCCACGCCGATGCCGGCCAGGCCTTGCCGGTGAGCCAACGGGTCGCCGCCGGCCATGCCCCC
GAGCCGCTCGCCAGCGGTACCTGCGCACGCATCTTCACCGGCGGTGAAATACCGCCGGGCGCCGACACGGTGGTCATGCA
AGAACGCGTGACGATGCATGAGCAGCTGGCCATCATTCCCGACGATATCGAATGCGGTGACAACGTGCGTCGCCGCGGGC
GCGATGTACGAGCCAGCACCCCCTTGCTGGAGGCCGGCACACGCCTGGAGGCCGCGGCGCTGGGGCATCTGGCCGGACAA
GGCATTACCCAGGTCGCCGTCCACCGCCGCCCTCGCATCGCCCTGCTTTCCACCGGGGACGAGATCGTCGAGCCCGGCCA
GACGCTCGCACCGGGACAGATTCACAATTCGAATCGCCCCATGCTGTCGCGCCTGCTCGAGCGCTTCGGCGCCGACCTGG
TCATGCGCGAACACGTCGCCGACGACTTCGCGACCACCCAGCGCCTGTTGGGCGACGCCGCCGCCTGTGCGGATATCATC
GTCACCACCGGTGGCGTCAGCGTCGGCGAGGAAGACCACGTCAAGCACGCCCTGGAATCCCTGGGACGACTCGACCTCTG
GCAGCTGGCCATGCGCCCTGGCAAGCCGCTGGCCTTGGGGCGGATCGGCGAGACGCGGGTGGTGGGGCTCCCCGGCAATC
CCGTGTCGTGCTTCGTGGGCGCCTGGGTCTATCTGCGCCCGCTGATCGGCGCCTTTCTTGCCTGTCCGCGCATGGCCACG
CTGCCGCGACTCTGGGCGCGTGCCGACTTCGAGACGCGCACCCAGGCGCGTCGCCACTACATGCGCGTGGGGCTCGAGTT
CACACCCGAGGGCGTCATCGCGCATGCCTTCGCCGATCAGAACTCCGCCGTGCTGTCCTCGTGCCTCGAGGCGGATGCCC
TGGCCGTCATCCCCGAGCACACGACCGTGCGAGCAGGCGAGCAGGTGGAATGTCTATGGCTCACGGAGTGA

Upstream 100 bases:

>100_bases
GCGTGCCGTACCGCCTGGGACGGCATCCTTCACGAACAGCTCGACAGCCGTCACAAGCCCTGCAACTTCGCCAATCTCGT
GATTCCCGGAAGAGGTCAGC

Downstream 100 bases:

>100_bases
GAACGCATTCCCCCGATGATGACGGCACCGGAAAAGCCTCTTGCCAGGCTGTGAAAGAAACGCCAAGGCGACTGAAGGCG
AGATCTAGTCGGCGCTCAAT

Product: MoeA-like protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAELQSVERALSALLDGVSPSEPEWIDCTQAAGRVLAETVTARLDVPPADNSAMDGYALRHADAGQALPVSQRVAAGHAP
EPLASGTCARIFTGGEIPPGADTVVMQERVTMHEQLAIIPDDIECGDNVRRRGRDVRASTPLLEAGTRLEAAALGHLAGQ
GITQVAVHRRPRIALLSTGDEIVEPGQTLAPGQIHNSNRPMLSRLLERFGADLVMREHVADDFATTQRLLGDAAACADII
VTTGGVSVGEEDHVKHALESLGRLDLWQLAMRPGKPLALGRIGETRVVGLPGNPVSCFVGAWVYLRPLIGAFLACPRMAT
LPRLWARADFETRTQARRHYMRVGLEFTPEGVIAHAFADQNSAVLSSCLEADALAVIPEHTTVRAGEQVECLWLTE

Sequences:

>Translated_396_residues
MAELQSVERALSALLDGVSPSEPEWIDCTQAAGRVLAETVTARLDVPPADNSAMDGYALRHADAGQALPVSQRVAAGHAP
EPLASGTCARIFTGGEIPPGADTVVMQERVTMHEQLAIIPDDIECGDNVRRRGRDVRASTPLLEAGTRLEAAALGHLAGQ
GITQVAVHRRPRIALLSTGDEIVEPGQTLAPGQIHNSNRPMLSRLLERFGADLVMREHVADDFATTQRLLGDAAACADII
VTTGGVSVGEEDHVKHALESLGRLDLWQLAMRPGKPLALGRIGETRVVGLPGNPVSCFVGAWVYLRPLIGAFLACPRMAT
LPRLWARADFETRTQARRHYMRVGLEFTPEGVIAHAFADQNSAVLSSCLEADALAVIPEHTTVRAGEQVECLWLTE
>Mature_395_residues
AELQSVERALSALLDGVSPSEPEWIDCTQAAGRVLAETVTARLDVPPADNSAMDGYALRHADAGQALPVSQRVAAGHAPE
PLASGTCARIFTGGEIPPGADTVVMQERVTMHEQLAIIPDDIECGDNVRRRGRDVRASTPLLEAGTRLEAAALGHLAGQG
ITQVAVHRRPRIALLSTGDEIVEPGQTLAPGQIHNSNRPMLSRLLERFGADLVMREHVADDFATTQRLLGDAAACADIIV
TTGGVSVGEEDHVKHALESLGRLDLWQLAMRPGKPLALGRIGETRVVGLPGNPVSCFVGAWVYLRPLIGAFLACPRMATL
PRLWARADFETRTQARRHYMRVGLEFTPEGVIAHAFADQNSAVLSSCLEADALAVIPEHTTVRAGEQVECLWLTE

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=414, Percent_Identity=28.2608695652174, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI10880983, Length=414, Percent_Identity=28.2608695652174, Blast_Score=152, Evalue=6e-37,
Organism=Escherichia coli, GI1787049, Length=312, Percent_Identity=41.9871794871795, Blast_Score=234, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI25147659, Length=385, Percent_Identity=30.6493506493506, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17562606, Length=322, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI17136978, Length=369, Percent_Identity=29.5392953929539, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24638841, Length=369, Percent_Identity=29.5392953929539, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 42453; Mature: 42322

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01079 MOCF_BIOSYNTHESIS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELQSVERALSALLDGVSPSEPEWIDCTQAAGRVLAETVTARLDVPPADNSAMDGYALR
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
HADAGQALPVSQRVAAGHAPEPLASGTCARIFTGGEIPPGADTVVMQERVTMHEQLAIIP
ECCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHEECC
DDIECGDNVRRRGRDVRASTPLLEAGTRLEAAALGHLAGQGITQVAVHRRPRIALLSTGD
CCCCCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCH
EIVEPGQTLAPGQIHNSNRPMLSRLLERFGADLVMREHVADDFATTQRLLGDAAACADII
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTTGGVSVGEEDHVKHALESLGRLDLWQLAMRPGKPLALGRIGETRVVGLPGNPVSCFVG
EECCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCEEEECCCCEEEEECCCCCHHHHHH
AWVYLRPLIGAFLACPRMATLPRLWARADFETRTQARRHYMRVGLEFTPEGVIAHAFADQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCC
NSAVLSSCLEADALAVIPEHTTVRAGEQVECLWLTE
CHHHHHHHHCCCCEEEECCCCEECCCCCEEEEEECC
>Mature Secondary Structure 
AELQSVERALSALLDGVSPSEPEWIDCTQAAGRVLAETVTARLDVPPADNSAMDGYALR
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
HADAGQALPVSQRVAAGHAPEPLASGTCARIFTGGEIPPGADTVVMQERVTMHEQLAIIP
ECCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHEECC
DDIECGDNVRRRGRDVRASTPLLEAGTRLEAAALGHLAGQGITQVAVHRRPRIALLSTGD
CCCCCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCH
EIVEPGQTLAPGQIHNSNRPMLSRLLERFGADLVMREHVADDFATTQRLLGDAAACADII
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTTGGVSVGEEDHVKHALESLGRLDLWQLAMRPGKPLALGRIGETRVVGLPGNPVSCFVG
EECCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCEEEECCCCEEEEECCCCCHHHHHH
AWVYLRPLIGAFLACPRMATLPRLWARADFETRTQARRHYMRVGLEFTPEGVIAHAFADQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCC
NSAVLSSCLEADALAVIPEHTTVRAGEQVECLWLTE
CHHHHHHHHCCCCEEEECCCCEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]