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The map label for this gene is moaB [H]

Identifier: 92114042

GI number: 92114042

Start: 2180021

End: 2180545

Strand: Direct

Name: moaB [H]

Synonym: Csal_1919

Alternate gene names: 92114042

Gene position: 2180021-2180545 (Clockwise)

Preceding gene: 92114041

Following gene: 92114043

Centisome position: 58.97

GC content: 64.19

Gene sequence:

>525_bases
ATGAGCGAGGCCGCCTTCATTCCTCTCAAGATCGCGGTGCTGACCGTCTCCGACACCCGCACCGCCGCGACCGACCGCTC
CGGTGACGCCCTGGTCGAACGCCTCGAGCGCGACGGCCACACGCTGGTCGAAAAGCGCATCGTCGCGGATGACGTCTATC
GTATCCGCGCGGTCGTTGCCCAATGGATTGCCGATGAGGATGTGCAAGTCATCGTCACCACCGGTGGCACGGGCTTCACC
GGGCGCGACTCCACGCCCGAAGCGATCGAGGTCCTGCTCGACAAGCACATCGAAGGCTTCGGCGAACTGTTTCGCCATCT
CTCGTGGCAGGAAATCGGCAGTTCCACGGTGCAAAGCCGTTGCCTGGGAGGCCTGGCCAACGCCACCGTGGTGTTCTGCC
TCCCGGGATCCACGGGGGCGTGCCGTACCGCCTGGGACGGCATCCTTCACGAACAGCTCGACAGCCGTCACAAGCCCTGC
AACTTCGCCAATCTCGTGATTCCCGGAAGAGGTCAGCATGGCTGA

Upstream 100 bases:

>100_bases
TGCCCTACAGCGAATGGAAAGCGCTCTACCAGGCCCCTGCCACGCCCGAGCAGCTCGCGGCCCTGGAAGCCCGCCAACAG
CGCAAGAAGGACACCCAGGC

Downstream 100 bases:

>100_bases
GCTGCAAAGCGTCGAACGTGCGCTGTCGGCACTGCTGGACGGCGTGAGCCCGAGCGAGCCCGAATGGATCGACTGCACGC
AAGCCGCCGGCCGCGTCCTG

Product: molybdopterin binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSEAAFIPLKIAVLTVSDTRTAATDRSGDALVERLERDGHTLVEKRIVADDVYRIRAVVAQWIADEDVQVIVTTGGTGFT
GRDSTPEAIEVLLDKHIEGFGELFRHLSWQEIGSSTVQSRCLGGLANATVVFCLPGSTGACRTAWDGILHEQLDSRHKPC
NFANLVIPGRGQHG

Sequences:

>Translated_174_residues
MSEAAFIPLKIAVLTVSDTRTAATDRSGDALVERLERDGHTLVEKRIVADDVYRIRAVVAQWIADEDVQVIVTTGGTGFT
GRDSTPEAIEVLLDKHIEGFGELFRHLSWQEIGSSTVQSRCLGGLANATVVFCLPGSTGACRTAWDGILHEQLDSRHKPC
NFANLVIPGRGQHG
>Mature_173_residues
SEAAFIPLKIAVLTVSDTRTAATDRSGDALVERLERDGHTLVEKRIVADDVYRIRAVVAQWIADEDVQVIVTTGGTGFTG
RDSTPEAIEVLLDKHIEGFGELFRHLSWQEIGSSTVQSRCLGGLANATVVFCLPGSTGACRTAWDGILHEQLDSRHKPCN
FANLVIPGRGQHG

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=148, Percent_Identity=33.1081081081081, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI66932975, Length=148, Percent_Identity=33.1081081081081, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1787000, Length=157, Percent_Identity=54.140127388535, Blast_Score=182, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17564954, Length=145, Percent_Identity=36.551724137931, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17136978, Length=145, Percent_Identity=35.8620689655172, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24638841, Length=145, Percent_Identity=35.8620689655172, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18852; Mature: 18721

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAAFIPLKIAVLTVSDTRTAATDRSGDALVERLERDGHTLVEKRIVADDVYRIRAVVA
CCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
QWIADEDVQVIVTTGGTGFTGRDSTPEAIEVLLDKHIEGFGELFRHLSWQEIGSSTVQSR
HHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
CLGGLANATVVFCLPGSTGACRTAWDGILHEQLDSRHKPCNFANLVIPGRGQHG
HHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SEAAFIPLKIAVLTVSDTRTAATDRSGDALVERLERDGHTLVEKRIVADDVYRIRAVVA
CCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
QWIADEDVQVIVTTGGTGFTGRDSTPEAIEVLLDKHIEGFGELFRHLSWQEIGSSTVQSR
HHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
CLGGLANATVVFCLPGSTGACRTAWDGILHEQLDSRHKPCNFANLVIPGRGQHG
HHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]