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The map label for this gene is dacC [H]

Identifier: 92113673

GI number: 92113673

Start: 1761908

End: 1762987

Strand: Direct

Name: dacC [H]

Synonym: Csal_1549

Alternate gene names: 92113673

Gene position: 1761908-1762987 (Clockwise)

Preceding gene: 92113672

Following gene: 92113674

Centisome position: 47.66

GC content: 62.96

Gene sequence:

>1080_bases
ATGGTACCGTCCGCGCCGGAGCTGGCGGCGTCGGCATGGGTATTGATGGACGCCGATAGCGGCAAGATCCTGGTCGAGCA
CAATGCCGACAAGGAACTGCCGCCGGCCAGTCTCACCAAGATGATGACGGCCTATATCGTCGAGCGCGAAATCGATGCCG
GCAACATCAGTGGCGACGACGAGGCCACGATCAGCGAAAACGCCTGGCGGACCGGCGGCTCGCGGATGTTTCTCAATCCG
GGCAGCAAGGTGAGCATCGACAATCTGCTCCGGGGCGTGGTGATCCAGTCGGGTAACGATGCCAGCGTGGCGCTGGCCGA
GCATATCGCGGGCAGCGAGGACGCCTTTGCCGATCTCATGAATCAGCAGGCGGCGCGGATGAAGCTCGAGCACACGCATT
TCATGAACCCCACCGGGCTGCCCCACGAGGAACACTACTCCTCGGCGCACGATCTGGCGGTCATCGCTCAGCACATCATC
AAGGACTACCCCGACCATTACGAGGTCTATTCCGAAAAGTACTTCACCTGGAACGACATTCGCCAGCCGAACCGCAACCG
CCTGCTATGGCGCGACCCGAACGTCGATGGCTTGAAGACGGGGCACACCGAGGCCGCCGGCTATTGCCTGGTCGCGTCCG
CCAAGAAGGACGGTACGCGCCTGGTGGCCGTGGTCATGGGAACCGACTCCGATGAAGCGCGGGCCCAGGAAACCCAGAAG
CTGCTGAGCTACGGGTTCCGCTTCTTCGAGACGCAACGTCTCTACGAAAGCGGCGCCGTGCTCAATACGCCCCGCATCTG
GGGAGGCGAGAAGGACGAATTGCGTCTGGGCGTCGCCGACGATGTCTACTTGACCGTGCCCCGTGGGCGCAGCGACGAGC
TGAGCGCTCAGCTCGACATTCGCGAAACCATCGAGGCGCCGGTGAGCGCGGGCGATCGCCTGGGAACCTTGAAGATCGTG
CTGGACGGCGAGGTGCTCGACGAGCGGCCGCTGGTGGCACTGGAGTCGATCGACGAGGGCGGCTTCTTCAAGCGGATCTG
GGATAGCGTGCTGCAGTTCGTGAACGGCTTCTTTGACTGA

Upstream 100 bases:

>100_bases
ACTGTTACGCGTTGTTCTACTGGTCACGCTATGTATCGGCGTCCTCGCGCCAACGGCACATGCCCAGAATCCACCGGAAC
CGTCGCCGGTGCCATCTTCC

Downstream 100 bases:

>100_bases
TCCGGCGGTGGAGGGTGGCGTCGGGTCGGCGCCGCCCTTGGTCGTCGCGGTAAGGTTGAGTAGAATACTCGGACATATCA
TGCCGAGCCCATACGAGGCC

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MVPSAPELAASAWVLMDADSGKILVEHNADKELPPASLTKMMTAYIVEREIDAGNISGDDEATISENAWRTGGSRMFLNP
GSKVSIDNLLRGVVIQSGNDASVALAEHIAGSEDAFADLMNQQAARMKLEHTHFMNPTGLPHEEHYSSAHDLAVIAQHII
KDYPDHYEVYSEKYFTWNDIRQPNRNRLLWRDPNVDGLKTGHTEAAGYCLVASAKKDGTRLVAVVMGTDSDEARAQETQK
LLSYGFRFFETQRLYESGAVLNTPRIWGGEKDELRLGVADDVYLTVPRGRSDELSAQLDIRETIEAPVSAGDRLGTLKIV
LDGEVLDERPLVALESIDEGGFFKRIWDSVLQFVNGFFD

Sequences:

>Translated_359_residues
MVPSAPELAASAWVLMDADSGKILVEHNADKELPPASLTKMMTAYIVEREIDAGNISGDDEATISENAWRTGGSRMFLNP
GSKVSIDNLLRGVVIQSGNDASVALAEHIAGSEDAFADLMNQQAARMKLEHTHFMNPTGLPHEEHYSSAHDLAVIAQHII
KDYPDHYEVYSEKYFTWNDIRQPNRNRLLWRDPNVDGLKTGHTEAAGYCLVASAKKDGTRLVAVVMGTDSDEARAQETQK
LLSYGFRFFETQRLYESGAVLNTPRIWGGEKDELRLGVADDVYLTVPRGRSDELSAQLDIRETIEAPVSAGDRLGTLKIV
LDGEVLDERPLVALESIDEGGFFKRIWDSVLQFVNGFFD
>Mature_359_residues
MVPSAPELAASAWVLMDADSGKILVEHNADKELPPASLTKMMTAYIVEREIDAGNISGDDEATISENAWRTGGSRMFLNP
GSKVSIDNLLRGVVIQSGNDASVALAEHIAGSEDAFADLMNQQAARMKLEHTHFMNPTGLPHEEHYSSAHDLAVIAQHII
KDYPDHYEVYSEKYFTWNDIRQPNRNRLLWRDPNVDGLKTGHTEAAGYCLVASAKKDGTRLVAVVMGTDSDEARAQETQK
LLSYGFRFFETQRLYESGAVLNTPRIWGGEKDELRLGVADDVYLTVPRGRSDELSAQLDIRETIEAPVSAGDRLGTLKIV
LDGEVLDERPLVALESIDEGGFFKRIWDSVLQFVNGFFD

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=362, Percent_Identity=45.3038674033149, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1786851, Length=358, Percent_Identity=46.0893854748603, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI87082022, Length=355, Percent_Identity=43.6619718309859, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI87082054, Length=238, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 39769; Mature: 39769

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPSAPELAASAWVLMDADSGKILVEHNADKELPPASLTKMMTAYIVEREIDAGNISGDD
CCCCCCCHHHCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
EATISENAWRTGGSRMFLNPGSKVSIDNLLRGVVIQSGNDASVALAEHIAGSEDAFADLM
CCEECCCCCCCCCCEEEECCCCCEEHHHHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHH
NQQAARMKLEHTHFMNPTGLPHEEHYSSAHDLAVIAQHIIKDYPDHYEVYSEKYFTWNDI
HHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEHHHC
RQPNRNRLLWRDPNVDGLKTGHTEAAGYCLVASAKKDGTRLVAVVMGTDSDEARAQETQK
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHH
LLSYGFRFFETQRLYESGAVLNTPRIWGGEKDELRLGVADDVYLTVPRGRSDELSAQLDI
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCEEECH
RETIEAPVSAGDRLGTLKIVLDGEVLDERPLVALESIDEGGFFKRIWDSVLQFVNGFFD
HHHHHCHHCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVPSAPELAASAWVLMDADSGKILVEHNADKELPPASLTKMMTAYIVEREIDAGNISGDD
CCCCCCCHHHCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
EATISENAWRTGGSRMFLNPGSKVSIDNLLRGVVIQSGNDASVALAEHIAGSEDAFADLM
CCEECCCCCCCCCCEEEECCCCCEEHHHHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHH
NQQAARMKLEHTHFMNPTGLPHEEHYSSAHDLAVIAQHIIKDYPDHYEVYSEKYFTWNDI
HHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEHHHC
RQPNRNRLLWRDPNVDGLKTGHTEAAGYCLVASAKKDGTRLVAVVMGTDSDEARAQETQK
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHH
LLSYGFRFFETQRLYESGAVLNTPRIWGGEKDELRLGVADDVYLTVPRGRSDELSAQLDI
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCEEECH
RETIEAPVSAGDRLGTLKIVLDGEVLDERPLVALESIDEGGFFKRIWDSVLQFVNGFFD
HHHHHCHHCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]