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The map label for this gene is prpE [H]

Identifier: 92113434

GI number: 92113434

Start: 1491933

End: 1492940

Strand: Direct

Name: prpE [H]

Synonym: Csal_1308

Alternate gene names: 92113434

Gene position: 1491933-1492940 (Clockwise)

Preceding gene: 92113433

Following gene: 92113435

Centisome position: 40.36

GC content: 65.18

Gene sequence:

>1008_bases
ATGACATTGCCTCGCCACGACCTCGATGGCTACGACTTGATCGGCGATGTCCACGGCTGTGGCGCATCGCTGGCCGTGCT
GCTGGAGAAGCTCGGCTATCGCCTGCAGGCGGGGGTGTACCGCCATCCGCGCCGCCGGGTGATCTTTCTCGGCGACCTGA
TCGATCGCGGCCCACGCATTCGGCTGGCGCTGAGCATCGCCTGGAACATGGTAGAAGCGGGGCAGGCGGATATCGTGATG
GGCAATCACGAATACAATGCCTTGGCCTATTGTCGTCGTTCGCCCCCGGGCTGGTCGGGAGAGTGGCTGCGTGAGCATTC
GCCGCGCCACAACCGCATCATCAACGAAACGCTGGCGCAGTTCCGCGAACATCCCCAGGAGTGGGATGCCTACCTGGATT
GGTTCATGGCGATGCCGCTGTGCCTCGAGCGCGATGGGCTGCGCGTGGTCCACGCCTGCTGGGACAGCGAGTTGATCGCG
GCATATCGCGAGCAATGTCCCGACGGGCGCATGAGCGAGGCGTTCTTTTACGATTCGGCGCGCCCGGGCACGTTCGCGTT
TCGTGTCATGGACCGGCTCACGCGCGGGCCGCATCTGCCGCTGCCGTCGGGGCTCAAGATCCATTCCGGCGATGGCTTCA
CGCGCAGTTCGTTCCGCGCGCACTTCTGGGCCCGCGACCCGCAAACCTATGGCGACGTGGTCTTCCAGCCCGACAACCTG
CCCGGCGGCATCGAAAACCAGCCGCTGCGCGCGGAAGAGCGTCGGCGCTTGCCTTACTATGGCCCGGACGAGCCGCCCTT
GTTTATCGGCCATTATTGGTGCGAGGGCATCCCGGCGCTGCCGGCACCGAATATCGCCTGTCTCGATTACAGCGCAGTGA
AGTATGGGCGCCTGGTGGCCTACCGCTGGGATGGAGAGCGGCGCCTGGATGCCAACCGCTTCGTGTGGGTCGAAGTGTCT
CGCGACGAACCGGCGCGATCCCGCCCGGACGACATCGAGCTGGCGTAG

Upstream 100 bases:

>100_bases
CGCAAGCGCGAACGCCTGACCCTGATTCACCCACGCGGACACAACTACTTCGAGACCTGTCGCACCAAGCTCGGCTGGAG
CAGCCGGTTGGGAGAGTGAC

Downstream 100 bases:

>100_bases
GGCGTCTGGCAGGCATCGCGGAAAGATTGAAAAAATTTTCGCCGCATTGGGAACTCATTGCGGTGGGCGTCGTCAGAGTA
GGTGTTCCCTTGAATGATCC

Product: hypothetical protein

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTLPRHDLDGYDLIGDVHGCGASLAVLLEKLGYRLQAGVYRHPRRRVIFLGDLIDRGPRIRLALSIAWNMVEAGQADIVM
GNHEYNALAYCRRSPPGWSGEWLREHSPRHNRIINETLAQFREHPQEWDAYLDWFMAMPLCLERDGLRVVHACWDSELIA
AYREQCPDGRMSEAFFYDSARPGTFAFRVMDRLTRGPHLPLPSGLKIHSGDGFTRSSFRAHFWARDPQTYGDVVFQPDNL
PGGIENQPLRAEERRRLPYYGPDEPPLFIGHYWCEGIPALPAPNIACLDYSAVKYGRLVAYRWDGERRLDANRFVWVEVS
RDEPARSRPDDIELA

Sequences:

>Translated_335_residues
MTLPRHDLDGYDLIGDVHGCGASLAVLLEKLGYRLQAGVYRHPRRRVIFLGDLIDRGPRIRLALSIAWNMVEAGQADIVM
GNHEYNALAYCRRSPPGWSGEWLREHSPRHNRIINETLAQFREHPQEWDAYLDWFMAMPLCLERDGLRVVHACWDSELIA
AYREQCPDGRMSEAFFYDSARPGTFAFRVMDRLTRGPHLPLPSGLKIHSGDGFTRSSFRAHFWARDPQTYGDVVFQPDNL
PGGIENQPLRAEERRRLPYYGPDEPPLFIGHYWCEGIPALPAPNIACLDYSAVKYGRLVAYRWDGERRLDANRFVWVEVS
RDEPARSRPDDIELA
>Mature_334_residues
TLPRHDLDGYDLIGDVHGCGASLAVLLEKLGYRLQAGVYRHPRRRVIFLGDLIDRGPRIRLALSIAWNMVEAGQADIVMG
NHEYNALAYCRRSPPGWSGEWLREHSPRHNRIINETLAQFREHPQEWDAYLDWFMAMPLCLERDGLRVVHACWDSELIAA
YREQCPDGRMSEAFFYDSARPGTFAFRVMDRLTRGPHLPLPSGLKIHSGDGFTRSSFRAHFWARDPQTYGDVVFQPDNLP
GGIENQPLRAEERRRLPYYGPDEPPLFIGHYWCEGIPALPAPNIACLDYSAVKYGRLVAYRWDGERRLDANRFVWVEVSR
DEPARSRPDDIELA

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.17 [H]

Molecular weight: Translated: 38545; Mature: 38414

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPRHDLDGYDLIGDVHGCGASLAVLLEKLGYRLQAGVYRHPRRRVIFLGDLIDRGPRI
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCHHHCCHHCCCCCEEEEEEHHHCCCCCE
RLALSIAWNMVEAGQADIVMGNHEYNALAYCRRSPPGWSGEWLREHSPRHNRIINETLAQ
EEEEEEEHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHH
FREHPQEWDAYLDWFMAMPLCLERDGLRVVHACWDSELIAAYREQCPDGRMSEAFFYDSA
HHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCC
RPGTFAFRVMDRLTRGPHLPLPSGLKIHSGDGFTRSSFRAHFWARDPQTYGDVVFQPDNL
CCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCEEECCCCC
PGGIENQPLRAEERRRLPYYGPDEPPLFIGHYWCEGIPALPAPNIACLDYSAVKYGRLVA
CCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCEEEECHHHHHHCEEEE
YRWDGERRLDANRFVWVEVSRDEPARSRPDDIELA
EEECCCCEECCCEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLPRHDLDGYDLIGDVHGCGASLAVLLEKLGYRLQAGVYRHPRRRVIFLGDLIDRGPRI
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCHHHCCHHCCCCCEEEEEEHHHCCCCCE
RLALSIAWNMVEAGQADIVMGNHEYNALAYCRRSPPGWSGEWLREHSPRHNRIINETLAQ
EEEEEEEHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHH
FREHPQEWDAYLDWFMAMPLCLERDGLRVVHACWDSELIAAYREQCPDGRMSEAFFYDSA
HHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCC
RPGTFAFRVMDRLTRGPHLPLPSGLKIHSGDGFTRSSFRAHFWARDPQTYGDVVFQPDNL
CCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCEEECCCCC
PGGIENQPLRAEERRRLPYYGPDEPPLFIGHYWCEGIPALPAPNIACLDYSAVKYGRLVA
CCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCEEEECHHHHHHCEEEE
YRWDGERRLDANRFVWVEVSRDEPARSRPDDIELA
EEECCCCEECCCEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA