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The map label for this gene is accD

Identifier: 92113389

GI number: 92113389

Start: 1441586

End: 1442518

Strand: Direct

Name: accD

Synonym: Csal_1263

Alternate gene names: 92113389

Gene position: 1441586-1442518 (Clockwise)

Preceding gene: 92113388

Following gene: 92113390

Centisome position: 39.0

GC content: 62.92

Gene sequence:

>933_bases
ATGAGCTGGCTAGACAAAATCGTGCCGTCAATGAGCCGTACCCAGCGAGCCGATCGCCGGAAAAGCGTGCCGGATGGCCT
GTGGCGTAAGTGCCCCAATTGCGAGGCGGTGCTCTATCTCCCCGAGCTGGAGCGCCACCAGAGCGTGTGCCCGAAATGCG
ATCACCATCTGCGCCTGACGGCCCGCAAGCGTCTCAACTGGTTTCTGGATACGGAAGGCCGCGAGGAAATCGCCGCCGAC
CTGCAGCCGGTCGACCGGCTCAAGTTCCGCGATTCCAAGAAATACAAGGATCGCCTCGCGGCGGCCCAGAAAGAGACCGA
CGAAAACGACGCCTTGATCGCCATGCGTGGCAAGCTCGATGGTCTGCCTGTCGTGGCGGTGGCCTTCGAGTTCAGTTTCA
TGGGCGGCTCGATGGGGGCCGTGGTGGGCGAAAAGTTCGTGCGTGCCGCGACCCAGGCCCGTGAAGAGGGCGTTCCGCTG
GTATGTTTCGCGGCCTCCGGCGGCGCGCGCATGCAGGAAGCCCTGTTCTCGCTGATGCAGATGGCCAAGACCTCCGCCGC
GCTGGAAAAGCTCAAGCAGGAAGGCGTGCCTTATATCTCGGTGCTCACCGATCCAGTGTTCGGTGGGGTGTCCGCCTCGC
TGGCCATGCTGGGTGATATCAATGTCGCAGAGCCCAACGCCCTGATCGGTTTCGCCGGGCCGCGCGTCATCGAGCAGACC
GTGCGTGAACAGCTGCCGGAAGGCTTCCAGCGCAGCGAGTTCCTGCTTGAGCACGGTACGGTGGACATGATCGTTCATCG
CCACGACATGCGCGAGCGCCTGGGTAGCGTCATGCGCAAGTTGACACACCAGCCGCATCAGGATCGTGATGCCGAGCCCG
ACGACACGGCATCGCAATCGACACTGGACGAGTTCTCCCAGGCCGATCACTGA

Upstream 100 bases:

>100_bases
CCGCTGATGCCCTACGGCATTCGCCAACGACTATTCGCTGCATGGGGCCACGGATGTGGCTTCATGCGTCAGACAAGCAA
CACGGAAGCGTCTCAGAACC

Downstream 100 bases:

>100_bases
ATGACTGCCGCGACCTCCCTGCAGGCCTGGCTGGCGCGCCTCGAACGCCAGCATCCCGTGGCGATCGACCTGGGCTTGGA
ACGCGTGGCCGAGGTCGCGC

Product: acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSWLDKIVPSMSRTQRADRRKSVPDGLWRKCPNCEAVLYLPELERHQSVCPKCDHHLRLTARKRLNWFLDTEGREEIAAD
LQPVDRLKFRDSKKYKDRLAAAQKETDENDALIAMRGKLDGLPVVAVAFEFSFMGGSMGAVVGEKFVRAATQAREEGVPL
VCFAASGGARMQEALFSLMQMAKTSAALEKLKQEGVPYISVLTDPVFGGVSASLAMLGDINVAEPNALIGFAGPRVIEQT
VREQLPEGFQRSEFLLEHGTVDMIVHRHDMRERLGSVMRKLTHQPHQDRDAEPDDTASQSTLDEFSQADH

Sequences:

>Translated_310_residues
MSWLDKIVPSMSRTQRADRRKSVPDGLWRKCPNCEAVLYLPELERHQSVCPKCDHHLRLTARKRLNWFLDTEGREEIAAD
LQPVDRLKFRDSKKYKDRLAAAQKETDENDALIAMRGKLDGLPVVAVAFEFSFMGGSMGAVVGEKFVRAATQAREEGVPL
VCFAASGGARMQEALFSLMQMAKTSAALEKLKQEGVPYISVLTDPVFGGVSASLAMLGDINVAEPNALIGFAGPRVIEQT
VREQLPEGFQRSEFLLEHGTVDMIVHRHDMRERLGSVMRKLTHQPHQDRDAEPDDTASQSTLDEFSQADH
>Mature_309_residues
SWLDKIVPSMSRTQRADRRKSVPDGLWRKCPNCEAVLYLPELERHQSVCPKCDHHLRLTARKRLNWFLDTEGREEIAADL
QPVDRLKFRDSKKYKDRLAAAQKETDENDALIAMRGKLDGLPVVAVAFEFSFMGGSMGAVVGEKFVRAATQAREEGVPLV
CFAASGGARMQEALFSLMQMAKTSAALEKLKQEGVPYISVLTDPVFGGVSASLAMLGDINVAEPNALIGFAGPRVIEQTV
REQLPEGFQRSEFLLEHGTVDMIVHRHDMRERLGSVMRKLTHQPHQDRDAEPDDTASQSTLDEFSQADH

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=211, Percent_Identity=27.0142180094787, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788655, Length=291, Percent_Identity=64.2611683848797, Blast_Score=394, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI25147359, Length=246, Percent_Identity=25.609756097561, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=246, Percent_Identity=25.609756097561, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_CHRSD (Q1QY40)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573317.1
- ProteinModelPortal:   Q1QY40
- SMR:   Q1QY40
- STRING:   Q1QY40
- GeneID:   4027584
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1263
- NMPDR:   fig|290398.4.peg.1253
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- BioCyc:   CSAL290398:CSAL_1263-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 34632; Mature: 34501

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50989 COA_CT_CTER; PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLDKIVPSMSRTQRADRRKSVPDGLWRKCPNCEAVLYLPELERHQSVCPKCDHHLRLT
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEECCCHHHHHCCCCCCCCHHHHH
ARKRLNWFLDTEGREEIAADLQPVDRLKFRDSKKYKDRLAAAQKETDENDALIAMRGKLD
HHHHHHHEECCCCHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
GLPVVAVAFEFSFMGGSMGAVVGEKFVRAATQAREEGVPLVCFAASGGARMQEALFSLMQ
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
MAKTSAALEKLKQEGVPYISVLTDPVFGGVSASLAMLGDINVAEPNALIGFAGPRVIEQT
HHHHHHHHHHHHHCCCCEEEEHHCHHHCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHH
VREQLPEGFQRSEFLLEHGTVDMIVHRHDMRERLGSVMRKLTHQPHQDRDAEPDDTASQS
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
TLDEFSQADH
HHHHHHHCCC
>Mature Secondary Structure 
SWLDKIVPSMSRTQRADRRKSVPDGLWRKCPNCEAVLYLPELERHQSVCPKCDHHLRLT
CHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEECCCHHHHHCCCCCCCCHHHHH
ARKRLNWFLDTEGREEIAADLQPVDRLKFRDSKKYKDRLAAAQKETDENDALIAMRGKLD
HHHHHHHEECCCCHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
GLPVVAVAFEFSFMGGSMGAVVGEKFVRAATQAREEGVPLVCFAASGGARMQEALFSLMQ
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
MAKTSAALEKLKQEGVPYISVLTDPVFGGVSASLAMLGDINVAEPNALIGFAGPRVIEQT
HHHHHHHHHHHHHCCCCEEEEHHCHHHCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHH
VREQLPEGFQRSEFLLEHGTVDMIVHRHDMRERLGSVMRKLTHQPHQDRDAEPDDTASQS
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
TLDEFSQADH
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA