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The map label for this gene is sufC [H]

Identifier: 92113360

GI number: 92113360

Start: 1413169

End: 1413921

Strand: Direct

Name: sufC [H]

Synonym: Csal_1234

Alternate gene names: 92113360

Gene position: 1413169-1413921 (Clockwise)

Preceding gene: 92113359

Following gene: 92113361

Centisome position: 38.23

GC content: 59.63

Gene sequence:

>753_bases
ATGCTCGAAGTCAAAGATCTGCACGTCACGGTGGAAGGTTCGGAAATCCTCAAGGGGTTGAGTTTGACCATCAATCCCGG
TGAGGTGCATGCCCTCATGGGGCCCAACGGGGCGGGCAAGTCGACGCTGTCGGCGGTGATCGCGGGCAAGGACGGCTACG
AAGTCACCAGTGGTCAGATCCTGTTCGAAGGCCAGGACCTGCTGGAAATGGAAATCGAGGAGCGTGCCCTGGCCGGTATT
CTGCTGGGTTTCCAGTATCCGGTGGAAATCCCCGGGGTGAAAAACATCTACCTGCTCAAGGCCGCGCTCAATGCGCAGCG
TGAAGCGCGCGGCGAGAAAGAGCTGCCGGCCCCGGAATTCATGAAACTGGTGCGCGAGAAGCTGAGCTTCATGAAGATGG
ATGGCAGCTTCCTGCAGCGTGCGGTCAACGAAGGGTTTTCGGGCGGCGAGAAAAAGCGCAACGAGATCCTGCAGATGCTG
GTACTGCAACCCAAGCTGGCGATGCTCGACGAGATCGACTCGGGGCTCGACATCGATGCCATGAAGATCGTCGCCGAAGG
GGTCAACTCGCTGCGCAGCCAGGATCGCGCCATTCTCATGGTGACCCACTACCAGCGGCTGCTCGAACATATCGTGCCGG
ATCATGTGCACGTCCTGGTGGACGGGCGCATCGTCAAGTCCGGCGACAAGAACCTCGCCCACGAGCTCGAAACGCGGGGT
TATGAATGGGTGCTGGAGGAGTCTGTCGCATGA

Upstream 100 bases:

>100_bases
CCCTCGAAGGCGCCGTCGGGTAAGCATTCCGGCGCATCGTCAAGGTTTCAACCCATGTATCGGAGTCGCCCGGCGACTCG
AACGCAAGCAAGGTATCAAG

Downstream 100 bases:

>100_bases
GTGCAGCACACGCCTTTCTACAACGGCTCGGCGAGCGATTCAGCGACGAGCCGACCTGGGTGACGGCACGTCGTCAGGCC
GGTGCAGCGCGCTTCGAGGC

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLEVKDLHVTVEGSEILKGLSLTINPGEVHALMGPNGAGKSTLSAVIAGKDGYEVTSGQILFEGQDLLEMEIEERALAGI
LLGFQYPVEIPGVKNIYLLKAALNAQREARGEKELPAPEFMKLVREKLSFMKMDGSFLQRAVNEGFSGGEKKRNEILQML
VLQPKLAMLDEIDSGLDIDAMKIVAEGVNSLRSQDRAILMVTHYQRLLEHIVPDHVHVLVDGRIVKSGDKNLAHELETRG
YEWVLEESVA

Sequences:

>Translated_250_residues
MLEVKDLHVTVEGSEILKGLSLTINPGEVHALMGPNGAGKSTLSAVIAGKDGYEVTSGQILFEGQDLLEMEIEERALAGI
LLGFQYPVEIPGVKNIYLLKAALNAQREARGEKELPAPEFMKLVREKLSFMKMDGSFLQRAVNEGFSGGEKKRNEILQML
VLQPKLAMLDEIDSGLDIDAMKIVAEGVNSLRSQDRAILMVTHYQRLLEHIVPDHVHVLVDGRIVKSGDKNLAHELETRG
YEWVLEESVA
>Mature_250_residues
MLEVKDLHVTVEGSEILKGLSLTINPGEVHALMGPNGAGKSTLSAVIAGKDGYEVTSGQILFEGQDLLEMEIEERALAGI
LLGFQYPVEIPGVKNIYLLKAALNAQREARGEKELPAPEFMKLVREKLSFMKMDGSFLQRAVNEGFSGGEKKRNEILQML
VLQPKLAMLDEIDSGLDIDAMKIVAEGVNSLRSQDRAILMVTHYQRLLEHIVPDHVHVLVDGRIVKSGDKNLAHELETRG
YEWVLEESVA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=220, Percent_Identity=30, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI42741659, Length=218, Percent_Identity=28.8990825688073, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI9961252, Length=235, Percent_Identity=30.6382978723404, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI9961250, Length=235, Percent_Identity=30.6382978723404, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4505771, Length=235, Percent_Identity=30.6382978723404, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI21536378, Length=221, Percent_Identity=24.4343891402715, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787972, Length=247, Percent_Identity=59.919028340081, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1787370, Length=232, Percent_Identity=29.7413793103448, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081709, Length=230, Percent_Identity=27.3913043478261, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=245, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789864, Length=244, Percent_Identity=26.6393442622951, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786319, Length=207, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789672, Length=230, Percent_Identity=26.9565217391304, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788225, Length=239, Percent_Identity=27.1966527196653, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789891, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788761, Length=224, Percent_Identity=26.3392857142857, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789593, Length=209, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787500, Length=273, Percent_Identity=27.8388278388278, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787029, Length=237, Percent_Identity=27.0042194092827, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=228, Percent_Identity=27.1929824561404, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790525, Length=223, Percent_Identity=30.0448430493274, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1787792, Length=238, Percent_Identity=25.6302521008403, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=218, Percent_Identity=29.8165137614679, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17558664, Length=234, Percent_Identity=31.1965811965812, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17565938, Length=229, Percent_Identity=28.3842794759825, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193202349, Length=230, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=225, Percent_Identity=29.7777777777778, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17543740, Length=190, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=232, Percent_Identity=28.8793103448276, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=232, Percent_Identity=28.8793103448276, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17510237, Length=233, Percent_Identity=27.8969957081545, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=233, Percent_Identity=27.0386266094421, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=236, Percent_Identity=27.9661016949153, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=233, Percent_Identity=26.6094420600858, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=233, Percent_Identity=26.6094420600858, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=232, Percent_Identity=28.8793103448276, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324498, Length=201, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319856, Length=236, Percent_Identity=28.8135593220339, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85816269, Length=230, Percent_Identity=29.1304347826087, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580553, Length=230, Percent_Identity=29.1304347826087, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85724864, Length=230, Percent_Identity=29.1304347826087, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580555, Length=230, Percent_Identity=29.1304347826087, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27611; Mature: 27611

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVKDLHVTVEGSEILKGLSLTINPGEVHALMGPNGAGKSTLSAVIAGKDGYEVTSGQI
CCEEEEEEEEEEHHHHHCCCEEEECCCEEEEEECCCCCCHHHHHHEEECCCCCEECCCEE
LFEGQDLLEMEIEERALAGILLGFQYPVEIPGVKNIYLLKAALNAQREARGEKELPAPEF
EECCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEHHHHHHHHHHHCCCCCCCCHHH
MKLVREKLSFMKMDGSFLQRAVNEGFSGGEKKRNEILQMLVLQPKLAMLDEIDSGLDIDA
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHH
MKIVAEGVNSLRSQDRAILMVTHYQRLLEHIVPDHVHVLVDGRIVKSGDKNLAHELETRG
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHHHHHHCC
YEWVLEESVA
CEEECCCCCC
>Mature Secondary Structure
MLEVKDLHVTVEGSEILKGLSLTINPGEVHALMGPNGAGKSTLSAVIAGKDGYEVTSGQI
CCEEEEEEEEEEHHHHHCCCEEEECCCEEEEEECCCCCCHHHHHHEEECCCCCEECCCEE
LFEGQDLLEMEIEERALAGILLGFQYPVEIPGVKNIYLLKAALNAQREARGEKELPAPEF
EECCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEHHHHHHHHHHHCCCCCCCCHHH
MKLVREKLSFMKMDGSFLQRAVNEGFSGGEKKRNEILQMLVLQPKLAMLDEIDSGLDIDA
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHH
MKIVAEGVNSLRSQDRAILMVTHYQRLLEHIVPDHVHVLVDGRIVKSGDKNLAHELETRG
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHHHHHHCC
YEWVLEESVA
CEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]