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The map label for this gene is cof [C]

Identifier: 92113354

GI number: 92113354

Start: 1407096

End: 1407896

Strand: Direct

Name: cof [C]

Synonym: Csal_1228

Alternate gene names: 92113354

Gene position: 1407096-1407896 (Clockwise)

Preceding gene: 92113353

Following gene: 92113358

Centisome position: 38.06

GC content: 64.42

Gene sequence:

>801_bases
ATGCAACCTCATTTGATCGTCACGGATCTGGACAACACGCTGCTCAATGCCGAGCACGATCTCGATGAATTGACCATCGA
GACCTTTCAGGCACTCGCCGCACGTGGACATCACCTGGCGTTGGCGTCTGGACGTCATTTTCACGATATCACGGCGTTCC
GCCGACGGCTGGGCGTGCCCGCGTACATCATGAGCACCAACGGGGCGCACCTCTACGGGCCCGACGACAGCCTTATCGCC
GAGCAGTGGGTGCCGGCCGAGCTGGTTCGGGCGTTGGTCGAGCTGCCGCGCGGTGCCGACATCCGGCTCAACCTGTATAC
CGGGGAGGAGTGGCTGATCGATGCGTCGGCGCCCGAGCTGAAGGCCTTGCACGCCCACACCGGATTCCACTATCGGGTGG
CCGATCTCGAGGCGCATGACGGCCGCGGCGTGGGCAAGGTGCTGTGCATCGGTGACCCCGAGGCCCTGGCAGCGCTGGAG
CAGAGCATCACCGAGACGCTGGGCACGCGGCTGCACATGACCTATTCGATGGCCCATTCGCTGGAGATCATGGCCGAGGG
TGTCAACAAGGGGGCCACGCTGGAACGGTTGCTGGCCCATCTCGGTCTCCCCGCCGCGCGGTGTCTGGCGTTCGGCGACA
ACCTCAACGATGCCGAGATGCTGGCGCTGGCCGGCCACGGGTTCGTCATGGAGAATGCGCATCCCGACCTGCCGCGTCGG
GTACCTGACGCCATCCGCATCGGTCACCATCATCCGAATGGCGTGGCCTGGCAGTTGCGCGATTTCTTTTCGCTGGCATG
A

Upstream 100 bases:

>100_bases
AATGCCTGCCGTGCACGCGGCCAGTATTCGACGGAACGATTCCCGGTGCCGATCCCACATGCGGTACTCTAGTCGCGTCG
AGGACCAATCAGGAAGCCGC

Downstream 100 bases:

>100_bases
GGTCTCGCCCGCGGTATCAATGCACGCTGATGACGCGGCAGGGCGCGGTATGCGAAACCTTGTGCGATACGCTGCCGACG
ACCAGACCGGCGATGTCGCT

Product: Cof protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MQPHLIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVPAYIMSTNGAHLYGPDDSLIA
EQWVPAELVRALVELPRGADIRLNLYTGEEWLIDASAPELKALHAHTGFHYRVADLEAHDGRGVGKVLCIGDPEALAALE
QSITETLGTRLHMTYSMAHSLEIMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLPRR
VPDAIRIGHHHPNGVAWQLRDFFSLA

Sequences:

>Translated_266_residues
MQPHLIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVPAYIMSTNGAHLYGPDDSLIA
EQWVPAELVRALVELPRGADIRLNLYTGEEWLIDASAPELKALHAHTGFHYRVADLEAHDGRGVGKVLCIGDPEALAALE
QSITETLGTRLHMTYSMAHSLEIMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLPRR
VPDAIRIGHHHPNGVAWQLRDFFSLA
>Mature_266_residues
MQPHLIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVPAYIMSTNGAHLYGPDDSLIA
EQWVPAELVRALVELPRGADIRLNLYTGEEWLIDASAPELKALHAHTGFHYRVADLEAHDGRGVGKVLCIGDPEALAALE
QSITETLGTRLHMTYSMAHSLEIMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLPRR
VPDAIRIGHHHPNGVAWQLRDFFSLA

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI48994981, Length=265, Percent_Identity=33.9622641509434, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI87081741, Length=248, Percent_Identity=32.258064516129, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI2367265, Length=277, Percent_Identity=25.6317689530686, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 29183; Mature: 29183

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPHLIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVP
CCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCC
AYIMSTNGAHLYGPDDSLIAEQWVPAELVRALVELPRGADIRLNLYTGEEWLIDASAPEL
EEEEECCCCEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCH
KALHAHTGFHYRVADLEAHDGRGVGKVLCIGDPEALAALEQSITETLGTRLHMTYSMAHS
HHHECCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEHHHHHH
LEIMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLPRR
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHEEEEECCCEEECCCCCCCCHH
VPDAIRIGHHHPNGVAWQLRDFFSLA
CCHHHCCCCCCCCCCEEHHHHHHHCC
>Mature Secondary Structure
MQPHLIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVP
CCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCC
AYIMSTNGAHLYGPDDSLIAEQWVPAELVRALVELPRGADIRLNLYTGEEWLIDASAPEL
EEEEECCCCEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCH
KALHAHTGFHYRVADLEAHDGRGVGKVLCIGDPEALAALEQSITETLGTRLHMTYSMAHS
HHHECCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEHHHHHH
LEIMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLPRR
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHEEEEECCCEEECCCCCCCCHH
VPDAIRIGHHHPNGVAWQLRDFFSLA
CCHHHCCCCCCCCCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]