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The map label for this gene is sdhB [H]

Identifier: 92113342

GI number: 92113342

Start: 1391207

End: 1391917

Strand: Direct

Name: sdhB [H]

Synonym: Csal_1216

Alternate gene names: 92113342

Gene position: 1391207-1391917 (Clockwise)

Preceding gene: 92113341

Following gene: 92113343

Centisome position: 37.63

GC content: 61.04

Gene sequence:

>711_bases
ATGTCCACGCTTCAGGTATCTATCTACCGCTACAACCCGGAAACCGACTCCGCGCCCTACATGCAGGAGTTCCAACTGGA
CACCCAGGGTCGCGATATCATGGTTCTCAATGCGCTTGAGATGATCAAGCAGCAGGACAGTTCCATGGCGTATCGTCGCA
GCTGCCGTGAAGGGGTTTGCGGTTCCGATGGCATGAACATGAACGGCAAGAACGGTCTGGCATGCATCACGCCGCTGTCC
GAGGTGGTCAAGGACAACAAGCTGGTGCTGCGTCCGTTGCCGGGCCTGCCGGTCATTCGTGACTTGGTGGTCGACATGGG
GGTGTTCTACAAGCAGTACGAGAGCATCCAGCCTTACCTGCAGAACGACACCAACCCGCCGGCCACGGAACGCCTGCAGT
CGCCGGAGGAGCGCGACAAGCTCGACGGTCTCTACGAGTGCATCCTGTGCGCCTGCTGCTCGACTGCGTGCCCGTCGTTC
TGGTGGAACCCGGACAAGTTCGTGGGGCCGGCCGGGTTGCTGCAGGCATATCGCTTCCTCGCCGATTCGCGCGACACCGC
CACGAGCGAGCGTCTGGCGCGGCTCGAGGACCCGTTCAGCCTGTTCCGCTGCCGCGGCATCATGAACTGCGTGGCGGTTT
GCCCCAAAGGGCTTAACCCGACACGGGCGATCGGCAAGATTCGCGAGATGTTACTGTCCAATGCCACTTAA

Upstream 100 bases:

>100_bases
CCGGTCGAAAAGCGCCTGGGACAGCGTGATGTGAACTTTGCGCCGAAGACCGTCGATACCTTCGAGCCGAAAATCCGCAC
TTACTAAGGGGTTGTCCAAG

Downstream 100 bases:

>100_bases
ATCGCGCCGCTTGGCTTGTTATCATTGGCAACAAGCCGCTTCCTGCGACAAGGCGTCGCAGGAAGCCGGTCCCGCGACCG
TTGCAGCCGGTGCCTCGTGC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSTLQVSIYRYNPETDSAPYMQEFQLDTQGRDIMVLNALEMIKQQDSSMAYRRSCREGVCGSDGMNMNGKNGLACITPLS
EVVKDNKLVLRPLPGLPVIRDLVVDMGVFYKQYESIQPYLQNDTNPPATERLQSPEERDKLDGLYECILCACCSTACPSF
WWNPDKFVGPAGLLQAYRFLADSRDTATSERLARLEDPFSLFRCRGIMNCVAVCPKGLNPTRAIGKIREMLLSNAT

Sequences:

>Translated_236_residues
MSTLQVSIYRYNPETDSAPYMQEFQLDTQGRDIMVLNALEMIKQQDSSMAYRRSCREGVCGSDGMNMNGKNGLACITPLS
EVVKDNKLVLRPLPGLPVIRDLVVDMGVFYKQYESIQPYLQNDTNPPATERLQSPEERDKLDGLYECILCACCSTACPSF
WWNPDKFVGPAGLLQAYRFLADSRDTATSERLARLEDPFSLFRCRGIMNCVAVCPKGLNPTRAIGKIREMLLSNAT
>Mature_235_residues
STLQVSIYRYNPETDSAPYMQEFQLDTQGRDIMVLNALEMIKQQDSSMAYRRSCREGVCGSDGMNMNGKNGLACITPLSE
VVKDNKLVLRPLPGLPVIRDLVVDMGVFYKQYESIQPYLQNDTNPPATERLQSPEERDKLDGLYECILCACCSTACPSFW
WNPDKFVGPAGLLQAYRFLADSRDTATSERLARLEDPFSLFRCRGIMNCVAVCPKGLNPTRAIGKIREMLLSNAT

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=237, Percent_Identity=53.5864978902954, Blast_Score=259, Evalue=2e-69,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=71.1206896551724, Blast_Score=349, Evalue=9e-98,
Organism=Escherichia coli, GI1790596, Length=232, Percent_Identity=36.6379310344828, Blast_Score=144, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=229, Percent_Identity=53.7117903930131, Blast_Score=253, Evalue=8e-68,
Organism=Saccharomyces cerevisiae, GI6322987, Length=227, Percent_Identity=54.625550660793, Blast_Score=253, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=52.3605150214592, Blast_Score=255, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24643156, Length=230, Percent_Identity=50.4347826086956, Blast_Score=233, Evalue=8e-62,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26502; Mature: 26371

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLQVSIYRYNPETDSAPYMQEFQLDTQGRDIMVLNALEMIKQQDSSMAYRRSCREGVC
CCCEEEEEEEECCCCCCCCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC
GSDGMNMNGKNGLACITPLSEVVKDNKLVLRPLPGLPVIRDLVVDMGVFYKQYESIQPYL
CCCCCCCCCCCCEEEEHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHH
QNDTNPPATERLQSPEERDKLDGLYECILCACCSTACPSFWWNPDKFVGPAGLLQAYRFL
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHH
ADSRDTATSERLARLEDPFSLFRCRGIMNCVAVCPKGLNPTRAIGKIREMLLSNAT
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STLQVSIYRYNPETDSAPYMQEFQLDTQGRDIMVLNALEMIKQQDSSMAYRRSCREGVC
CCEEEEEEEECCCCCCCCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC
GSDGMNMNGKNGLACITPLSEVVKDNKLVLRPLPGLPVIRDLVVDMGVFYKQYESIQPYL
CCCCCCCCCCCCEEEEHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHH
QNDTNPPATERLQSPEERDKLDGLYECILCACCSTACPSFWWNPDKFVGPAGLLQAYRFL
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHH
ADSRDTATSERLARLEDPFSLFRCRGIMNCVAVCPKGLNPTRAIGKIREMLLSNAT
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]