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The map label for this gene is guaA [H]

Identifier: 92113309

GI number: 92113309

Start: 1355027

End: 1355758

Strand: Direct

Name: guaA [H]

Synonym: Csal_1182

Alternate gene names: 92113309

Gene position: 1355027-1355758 (Clockwise)

Preceding gene: 92113308

Following gene: 92113313

Centisome position: 36.66

GC content: 61.34

Gene sequence:

>732_bases
ATGACACTGAAGATCGGCATACTGGCCACCGGCACGACGCCGGACAATCTGATCGACCAGTATGGCTCCTACGCCGACAT
GTTCGTTCGTCTGTTCGAACAGGCCGGCTATGGCTTTACCTTCACTACCTACGATGTGCGCGACGACGTCTTTCCCGAGT
CAGCCGATGCCTGCGATGCCTGGATCATCACCGGCTCGAAGTTCAGCGTCTGCGACAAGTCGCCATGGATGGCACGGTTG
AAAGACCTGATTCTCGACATCTATGACACCGGCGGCCCGATCGTGGGCATTTGCTTCGGCCACCAGATCGTGGCGGAAGC
CTTCGGCGCCGACGTCGATCGGTATCCGCAAGGCTGGGGCGTGGGATTGCATACCTACCGACTGGAGAAGAACGTAGCGG
AGCTGAGCGCCCTGGATGGCCGATTCACGCTGAATGCAGTGCATCAGGATCAGGTGCTGAGCAAACCGGAGCAGGCTGAC
GTCATCGCCTCTTCGTCGTTCTGCCCGTTTGCGGCCCTCCAGTACGACGATCGCATCCTGACCCTGCAGGCGCATCCAGA
GTTCGACGTGGCGTTCGAAACGCGGTTGCTTCAGTCACGTCGTGATGCCCCGATTCCGTCGAGCGCGACCGATCCGGCGC
TGGTCGCGCTCGACGAGGCGTCGGCGCAGACGGACTCGCTGCAGGTCGCCCACTGGATGGCCGAGTTCCTGCAGCAGGGT
CGACGTCGTTGA

Upstream 100 bases:

>100_bases
GAGCGCATCTCCGATGTTGAATATGAGGCCTATCTGGGATTGCTCTGATCCCGGCCAGGCCTGAAAAATTCACGGCGCGG
CCGTGAGCGAGGAATCCGTC

Downstream 100 bases:

>100_bases
GCGTGCCCACGCGTTGTCTGAACGCCCGGCTTGCCCATACCGCGCTTGATGCGACCATCCGGGATCAAGCGGGCCATGTC
GCGATAGCCCGATGATCCCG

Product: glutamine amidotransferase class-I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTLKIGILATGTTPDNLIDQYGSYADMFVRLFEQAGYGFTFTTYDVRDDVFPESADACDAWIITGSKFSVCDKSPWMARL
KDLILDIYDTGGPIVGICFGHQIVAEAFGADVDRYPQGWGVGLHTYRLEKNVAELSALDGRFTLNAVHQDQVLSKPEQAD
VIASSSFCPFAALQYDDRILTLQAHPEFDVAFETRLLQSRRDAPIPSSATDPALVALDEASAQTDSLQVAHWMAEFLQQG
RRR

Sequences:

>Translated_243_residues
MTLKIGILATGTTPDNLIDQYGSYADMFVRLFEQAGYGFTFTTYDVRDDVFPESADACDAWIITGSKFSVCDKSPWMARL
KDLILDIYDTGGPIVGICFGHQIVAEAFGADVDRYPQGWGVGLHTYRLEKNVAELSALDGRFTLNAVHQDQVLSKPEQAD
VIASSSFCPFAALQYDDRILTLQAHPEFDVAFETRLLQSRRDAPIPSSATDPALVALDEASAQTDSLQVAHWMAEFLQQG
RRR
>Mature_242_residues
TLKIGILATGTTPDNLIDQYGSYADMFVRLFEQAGYGFTFTTYDVRDDVFPESADACDAWIITGSKFSVCDKSPWMARLK
DLILDIYDTGGPIVGICFGHQIVAEAFGADVDRYPQGWGVGLHTYRLEKNVAELSALDGRFTLNAVHQDQVLSKPEQADV
IASSSFCPFAALQYDDRILTLQAHPEFDVAFETRLLQSRRDAPIPSSATDPALVALDEASAQTDSLQVAHWMAEFLQQGR
RR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323155, Length=218, Percent_Identity=33.0275229357798, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 26911; Mature: 26780

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKIGILATGTTPDNLIDQYGSYADMFVRLFEQAGYGFTFTTYDVRDDVFPESADACDA
CEEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCE
WIITGSKFSVCDKSPWMARLKDLILDIYDTGGPIVGICFGHQIVAEAFGADVDRYPQGWG
EEEECCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHCCCCCC
VGLHTYRLEKNVAELSALDGRFTLNAVHQDQVLSKPEQADVIASSSFCPFAALQYDDRIL
CCEEEEEHHHHHHHHHHCCCCEEEEECCHHHHHCCCCHHHEEECCCCCCEEEEECCCEEE
TLQAHPEFDVAFETRLLQSRRDAPIPSSATDPALVALDEASAQTDSLQVAHWMAEFLQQG
EEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
RRR
CCC
>Mature Secondary Structure 
TLKIGILATGTTPDNLIDQYGSYADMFVRLFEQAGYGFTFTTYDVRDDVFPESADACDA
EEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCE
WIITGSKFSVCDKSPWMARLKDLILDIYDTGGPIVGICFGHQIVAEAFGADVDRYPQGWG
EEEECCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHCCCCCC
VGLHTYRLEKNVAELSALDGRFTLNAVHQDQVLSKPEQADVIASSSFCPFAALQYDDRIL
CCEEEEEHHHHHHHHHHCCCCEEEEECCHHHHHCCCCHHHEEECCCCCCEEEEECCCEEE
TLQAHPEFDVAFETRLLQSRRDAPIPSSATDPALVALDEASAQTDSLQVAHWMAEFLQQG
EEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
RRR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]