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The map label for this gene is sdaA [H]

Identifier: 92113110

GI number: 92113110

Start: 1101688

End: 1103067

Strand: Direct

Name: sdaA [H]

Synonym: Csal_0982

Alternate gene names: 92113110

Gene position: 1101688-1103067 (Clockwise)

Preceding gene: 92113107

Following gene: 92113111

Centisome position: 29.8

GC content: 64.93

Gene sequence:

>1380_bases
ATGGCGATCAGTGTGTTCGATCTGTTCAAGGTGGGGATTGGCCCGTCCAGTTCGCATACCGTGGGTCCCATGCGTGCCGC
TCACGATTTCGTCGAGGCATTGCGTGCCCGCGATGCGTTGTCGCGCGTGACTCGCGTCGAGGTTCATCTTCACGGATCGC
TCTGCGCCACCGGCGTAGGCCATGGTACGGACCGTGCGGTGATCATGGGGCTCATGGGCGAGCGTCCCGAGAGTATCGAC
CCCGACATCGTGCCCGCCTGCATCGAGGAACTGCACGAATCGCAGACCCTGCTGCTGGGCGGCCTGGTGCCGATCTCATT
TCCCTGGTCGCGGGACATGCAATGGCACGAGGACTCGCTCGACTATCATCCCAATGCGCTGCGCCTGATCGCGCATGCGC
ACGACGGGGAGTGCTATCGCAATACCTATTATTCGGTCGGCGGCGGCTTCGTCATCGACGAGGCCCAGGCCGCCAATGGC
GCGCTGGACACCGACACCACGACGTTGCCCTATGACTTTGCGACGGCGGATGAGTTGCTGTCGCTGTGCCGCACCCATGG
ATTGCGCATTTCCGAGCTGATGCTCGAGAACGAGAAAGCCTGGCGCGACGAGGCCAGCGTCCGCGATGCGCTGTGGCATA
TCTGGGAGGCGATGAAAGCCTGCGTCGACAACGGCCTGCGGCACGATGGCGTCCTGCCCGGCGGGCTCAACGTCAAGCGC
CGTGCCAGTGCGCTGCATCGGCGTCTGCAAGCGGCCAAGGACGACACCAGCGTGATCGCCTCGACATTTTCGGCCATGGA
CTGGGTCAACGTCTTCGCCCTGGCGGTCAACGAGGAAAACGCCGCCGGCGGGCGCATGGTCACCGCGCCGACCAACGGGG
CGGCGGGCATCGTGCCGGCGGTCTTGCACTATTACATGCGTTTCCAGCCCGGTGCCTGCCAGCGCGATGTCGTCGACTTC
CTGCTGGCGGCGGGAGCGATCGGCATTCTGTGCAAGAAGAATGCCTCGATTTCCGGCGCCGAGGTCGGCTGTCAGGGCGA
GGTCGGATCGGCCTGCGCGATGGCCGCCGCCGGACTGGCCGAGGTCATGGGCGGAACGCCCGCCCAGGTGGAGAACGCCG
CCGAGATCGGCCTCGAGCACAACCTGGGATTGACCTGCGACCCCATCGGGGGCCTGGTGCAGGTCCCTTGCATCGAACGC
AATGCCATCGCCTCGGTGAAGGCGATAAACGCCGCGCAGATGGCGCTTGGCGGCGATGGCGAGCACTTCGTTTCTCTCGA
CCGGGTCATCCGCACCATGCGCGATACAGGGCGTGACATGCAGGACAAGTACAAGGAGACCTCGCGCGGCGGCCTGGCGG
TCAATGCCATCGAATGCTGA

Upstream 100 bases:

>100_bases
GTTGCCCGGCACTCGGGCTGGCTTCAAGCTAGAGTCAATGTCAGCGAATGGCAAGTTCGTTTAGAAATTTTGATGCATGA
CCACCCCGAGGGATCACGTT

Downstream 100 bases:

>100_bases
AGCCTGCTTGCTCGATCAACCCTTTGGGACGCCGCTCGGCGTCCTTTTTTTTGTTTCGGGATCGCGCCGTCGCGCCTTGT
ATGGTTTTATTTCGTCGGAA

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAISVFDLFKVGIGPSSSHTVGPMRAAHDFVEALRARDALSRVTRVEVHLHGSLCATGVGHGTDRAVIMGLMGERPESID
PDIVPACIEELHESQTLLLGGLVPISFPWSRDMQWHEDSLDYHPNALRLIAHAHDGECYRNTYYSVGGGFVIDEAQAANG
ALDTDTTTLPYDFATADELLSLCRTHGLRISELMLENEKAWRDEASVRDALWHIWEAMKACVDNGLRHDGVLPGGLNVKR
RASALHRRLQAAKDDTSVIASTFSAMDWVNVFALAVNEENAAGGRMVTAPTNGAAGIVPAVLHYYMRFQPGACQRDVVDF
LLAAGAIGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEVMGGTPAQVENAAEIGLEHNLGLTCDPIGGLVQVPCIER
NAIASVKAINAAQMALGGDGEHFVSLDRVIRTMRDTGRDMQDKYKETSRGGLAVNAIEC

Sequences:

>Translated_459_residues
MAISVFDLFKVGIGPSSSHTVGPMRAAHDFVEALRARDALSRVTRVEVHLHGSLCATGVGHGTDRAVIMGLMGERPESID
PDIVPACIEELHESQTLLLGGLVPISFPWSRDMQWHEDSLDYHPNALRLIAHAHDGECYRNTYYSVGGGFVIDEAQAANG
ALDTDTTTLPYDFATADELLSLCRTHGLRISELMLENEKAWRDEASVRDALWHIWEAMKACVDNGLRHDGVLPGGLNVKR
RASALHRRLQAAKDDTSVIASTFSAMDWVNVFALAVNEENAAGGRMVTAPTNGAAGIVPAVLHYYMRFQPGACQRDVVDF
LLAAGAIGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEVMGGTPAQVENAAEIGLEHNLGLTCDPIGGLVQVPCIER
NAIASVKAINAAQMALGGDGEHFVSLDRVIRTMRDTGRDMQDKYKETSRGGLAVNAIEC
>Mature_458_residues
AISVFDLFKVGIGPSSSHTVGPMRAAHDFVEALRARDALSRVTRVEVHLHGSLCATGVGHGTDRAVIMGLMGERPESIDP
DIVPACIEELHESQTLLLGGLVPISFPWSRDMQWHEDSLDYHPNALRLIAHAHDGECYRNTYYSVGGGFVIDEAQAANGA
LDTDTTTLPYDFATADELLSLCRTHGLRISELMLENEKAWRDEASVRDALWHIWEAMKACVDNGLRHDGVLPGGLNVKRR
ASALHRRLQAAKDDTSVIASTFSAMDWVNVFALAVNEENAAGGRMVTAPTNGAAGIVPAVLHYYMRFQPGACQRDVVDFL
LAAGAIGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEVMGGTPAQVENAAEIGLEHNLGLTCDPIGGLVQVPCIERN
AIASVKAINAAQMALGGDGEHFVSLDRVIRTMRDTGRDMQDKYKETSRGGLAVNAIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=458, Percent_Identity=54.8034934497817, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1789161, Length=458, Percent_Identity=53.4934497816594, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=52.2975929978118, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49052; Mature: 48921

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISVFDLFKVGIGPSSSHTVGPMRAAHDFVEALRARDALSRVTRVEVHLHGSLCATGVG
CEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHCCCCC
HGTDRAVIMGLMGERPESIDPDIVPACIEELHESQTLLLGGLVPISFPWSRDMQWHEDSL
CCCCHHHHEEHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCEECCCCCCCCCCCCCCC
DYHPNALRLIAHAHDGECYRNTYYSVGGGFVIDEAQAANGALDTDTTTLPYDFATADELL
CCCCCCEEEEEECCCCCHHHCCEEECCCCEEEECCHHCCCCCCCCCCCCCCCCCCHHHHH
SLCRTHGLRISELMLENEKAWRDEASVRDALWHIWEAMKACVDNGLRHDGVLPGGLNVKR
HHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RASALHRRLQAAKDDTSVIASTFSAMDWVNVFALAVNEENAAGGRMVTAPTNGAAGIVPA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCHHHHH
VLHYYMRFQPGACQRDVVDFLLAAGAIGILCKKNASISGAEVGCQGEVGSACAMAAAGLA
HHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
EVMGGTPAQVENAAEIGLEHNLGLTCDPIGGLVQVPCIERNAIASVKAINAAQMALGGDG
HHHCCCCHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCC
EHFVSLDRVIRTMRDTGRDMQDKYKETSRGGLAVNAIEC
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
AISVFDLFKVGIGPSSSHTVGPMRAAHDFVEALRARDALSRVTRVEVHLHGSLCATGVG
EEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHCCCCC
HGTDRAVIMGLMGERPESIDPDIVPACIEELHESQTLLLGGLVPISFPWSRDMQWHEDSL
CCCCHHHHEEHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCEECCCCCCCCCCCCCCC
DYHPNALRLIAHAHDGECYRNTYYSVGGGFVIDEAQAANGALDTDTTTLPYDFATADELL
CCCCCCEEEEEECCCCCHHHCCEEECCCCEEEECCHHCCCCCCCCCCCCCCCCCCHHHHH
SLCRTHGLRISELMLENEKAWRDEASVRDALWHIWEAMKACVDNGLRHDGVLPGGLNVKR
HHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RASALHRRLQAAKDDTSVIASTFSAMDWVNVFALAVNEENAAGGRMVTAPTNGAAGIVPA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCHHHHH
VLHYYMRFQPGACQRDVVDFLLAAGAIGILCKKNASISGAEVGCQGEVGSACAMAAAGLA
HHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
EVMGGTPAQVENAAEIGLEHNLGLTCDPIGGLVQVPCIERNAIASVKAINAAQMALGGDG
HHHCCCCHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCC
EHFVSLDRVIRTMRDTGRDMQDKYKETSRGGLAVNAIEC
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]